+C Two-component system KO
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Two-Component System - Pseudomonas fluorescens A506
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C PflA506_5322 phoR; phosphate regulon sensor kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C PflA506_5321 phoB; phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
C PflA506_4026 phoQ; sensor protein PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C PflA506_4027 phoP; DNA-binding response regulator PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
B EnvZ-OmpR (osmotic stress response)
C PflA506_0260 envZ; osmolarity sensor protein EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C PflA506_0259 ompR; DNA-binding response regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C PflA506_4030 sensor histidine kinase K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C PflA506_4031 DNA-binding response regulator K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C PflA506_4184 DNA-binding response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C PflA506_4937 creC; sensor histidine kinase CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C PflA506_4938 creB; DNA-binding response regulator CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C PflA506_0681 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PflA506_0939 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PflA506_1588 copS; copper sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PflA506_3480 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PflA506_0682 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C PflA506_0940 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C PflA506_1589 copR; DNA-binding copper response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C PflA506_3479 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
C PflA506_3685 sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C PflA506_3686 DNA-binding response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C PflA506_1726 kdpD; sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C PflA506_1727 kdpE; KDP operon transcriptional regulatory protein KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C PflA506_1394 sensor histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C PflA506_1393 DNA-binding response regulator K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
C PflA506_2548 sensor protein RstB, putative K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
C PflA506_2547 transcriptional regulatory protein RstA, putative K18073 parR; two-component system, OmpR family, response regulator ParR
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
C PflA506_3157 sensor histidine kinase K19609 pfeS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]
C PflA506_3158 DNA-binding response regulator K19610 pfeR; two-component system, OmpR family, response regulator PfeR
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C PflA506_2967 rpeA; sensor histidine kinase RpeA K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C PflA506_1872 DNA-binding response regulator, OmpR family K02483 K02483; two-component system, OmpR family, response regulator
C PflA506_2088 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C PflA506_2666 two component transcriptional regulatory protein K02483 K02483; two-component system, OmpR family, response regulator
C PflA506_2968 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C PflA506_3038 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C PflA506_4271 gltR; DNA-binding response regulator GltR K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
C PflA506_0384 DNA-binding response regulator, LuxR family K20264 fusR; two-component system, NarL family, response regulator FusR
B RcsC-RcsD-RcsB (capsule synthesis)
C PflA506_3426 sensor histidine kinase/response regulator K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C PflA506_3428 sensor histidine kinase/response regulator K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C PflA506_0997 DNA-binding response regulator, LuxR family K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C PflA506_3429 DNA-binding response regulator, LuxR family K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C PflA506_4311 DNA-binding response regulator, LuxR family K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
B BarA-UvrY (central carbon metabolism)
C PflA506_3159 gacS; sensor protein GacS K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C PflA506_2155 gacA; response regulator GacA K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C PflA506_1783 sensory box histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C PflA506_2147 sensor histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C PflA506_4312 sensory box histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C PflA506_1124 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
C PflA506_1784 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
C PflA506_2146 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
C PflA506_0616 pprA; two-component sensor histidine kinase PprA K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]
C PflA506_0619 pprB; two-component response regulator PprB K27077 pprB; two-component system, NarL family, response regulator PprB
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C PflA506_5220 algR; DNA-binding response regulator AlgR K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B BtsS-BtsR (pyruvate reutilization)
B PyrS-PyrR (pyruvate reutilization)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C PflA506_0330 glnL; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C PflA506_0329 glnG; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C PflA506_4531 cbrB; two-component response regulator CbrB K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C PflA506_0284 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C PflA506_4262 dctB; C4-dicarboxylate transport sensor protein DctB K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C PflA506_0283 sigma-54 dependent DNA-binding response regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C PflA506_4263 dctD; C4-dicarboxylate transport transcriptional regulatory protein DctD K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
C PflA506_0086 kinB; alginate biosynthesis sensor protein KinB K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
C PflA506_0087 algB; alginate biosynthesis transcriptional regulatory protein AlgB K11384 algB; two-component system, NtrC family, response regulator AlgB
B HupT-HupR (hydrogenase synthesis regulation)
C PflA506_2656 formyl transferase domain/enoyl-CoA hydratase/isomerase family protein K19640 hypX; putative two-component system protein, hydrogenase maturation factor HypX/HoxX
B Unclassified
C PflA506_1080 response regulator/sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C PflA506_1081 sensor histidine kinase, putative K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C PflA506_3717 cheA; chemotaxis sensor histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C PflA506_3719 cheY; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C PflA506_2707 protein-glutamate methylesterase, CheB family K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C PflA506_3716 cheB; chemotaxis response regulator/protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C PflA506_2177 methylesterase, CheB family/methyltransferase, CheR family/sensor histidine kinase/response regulator K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
C PflA506_0947 CheW-like domain protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C PflA506_3705 CheW-like domain protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C PflA506_4039 response regulator receiver domain/CheW-like domain protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
C PflA506_5046 chpA; sensor histidine kinase/response regulator ChpA, putative K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C PflA506_5050 pilG; type IV pilus response regulator PilG K02657 pilG; twitching motility two-component system response regulator PilG
C PflA506_5049 pilH; type IV pilus response regulator PilH K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
C PflA506_1188 sensor histidine kinase/response regulator K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
C PflA506_1190 response regulator/diguanylate cyclase domain protein K11444 wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65]
C PflA506_1189 response regulator domain/methylesterase, CheB family K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
B Cph1-Rcp1 (light response)
C PflA506_4411 bphP; bacteriophytochrome histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
C PflA506_2705 response regulator K13589 cpdR; two-component system, cell cycle response regulator CpdR
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C PflA506_3748 fleS; sensory box histidine kinase FleS K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C PflA506_3747 fleR; sigma-54 dependent DNA-binding response regulator FleR K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
C PflA506_1103 sensor histidine kinase K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
C PflA506_1102 sigma-54 dependent DNA-binding response regulator K17061 aauR; two-component system, response regulator AauR
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C PflA506_0820 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C PflA506_0821 DNA-binding response regulator, Fis family K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C PflA506_1780 sensor histidine kinase/response regulator K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
C PflA506_1859 sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
C PflA506_3738 HPt domain protein K20976 hptB; histidine phosphotransfer protein HptB
C PflA506_3739 response regulator K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator
B PdtaS-PdtaR
B NasS-NasT
C PflA506_3907 nasS; nitrate-binding protein NasS K22067 nasS; two-component system, oxyanion-binding sensor
C PflA506_3908 nasT; response regulator NasT K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
C PflA506_4684 ladS; sensor histidine kinase/response regulator K20971 ladS; two-component system, sensor histidine kinase LadS
C PflA506_0590 retS; sensor histidine kinase/response regulator RetS K20972 retS; two-component system, sensor histidine kinase RetS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 8, 2024