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Mitochondrial Biogenesis - Plasmodium falciparum Dd2
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
C Mitochondrial respiratory chain complex III
C Cytochrome c oxidase
D PFDG_00559 hypothetical protein similar to cytochrome c oxidase subunit II K02261 COX2; cytochrome c oxidase subunit 2
C F-type ATPase
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D PFDG_03655 hypothetical protein similar to DNA-dependent RNA polymerase K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
C Mitochondrial translation factors
D PFDG_00047 conserved hypothetical protein K02519 infB; translation initiation factor IF-2
D PFDG_03742 hypothetical protein K02519 infB; translation initiation factor IF-2
D PFDG_02308 hypothetical protein similar to elongation factor K02357 tsf; elongation factor Ts
D PFDG_03670 hypothetical protein K02358 tuf; elongation factor Tu
D PFDG_02476 hypothetical protein similar to small GTP-binding protein domain K02355 fusA; elongation factor G
D PFDG_02044 hypothetical protein K02355 fusA; elongation factor G
C RNase MRP
D PFDG_01575 hypothetical protein K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D PFDG_00794 hypothetical protein K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D PFDG_03980 conserved hypothetical protein K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
C Other mitochondrial DNA transcription and translation factors
D PFDG_02502 hypothetical protein K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D PFDG_01376 hypothetical protein similar to tyrosine-tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D PFDG_00036 hypothetical protein similar to leucine-tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PFDG_02921 hypothetical protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PFDG_01390 hypothetical protein K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D PFDG_03192 hypothetical protein similar to glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D PFDG_03614 conserved hypothetical protein K19828 MTG1; mitochondrial GTPase 1
D PFDG_01236 conserved hypothetical protein K23498 COXPD7; peptide chain release factor
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
C Mitochondrial DNA maintenance factors
C Other Mitochondrial DNA replication factors
D PFDG_00819 hypothetical protein K03111 ssb; single-strand DNA-binding protein
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D PFDG_02528 conserved hypothetical protein K09503 DNAJA2; DnaJ homolog subfamily A member 2
D PFDG_01460 heat shock protein 70 kDa K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
B Outer membrane
C Transporter outer membrane (TOM) complex
D PFDG_04063 hypothetical protein K11518 TOM40; mitochondrial import receptor subunit TOM40
D PFDG_04960 hypothetical protein similar to mitochondrial import receptor subunit K11518 TOM40; mitochondrial import receptor subunit TOM40
C TOB/SAM complex
C Porin
C ERMES complex
C Other outer membrane factor
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D PFDG_03909 hypothetical protein K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
C TIM8/13 complex
D PFDG_01630 hypothetical protein K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D PFDG_01093 hypothetical protein K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
C MICOS complex (yeast)
C TIM22 complex
D PFDG_02555 hypothetical protein similar to mitochondrial import inner membrane translocase subunit K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
C TIM23 complex
D PFDG_00584 mitochondrial import inner membrane translocase subunit tim-17 K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D PFDG_00133 conserved hypothetical protein K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
C Other inner membrane factors
D PFDG_04159 conserved hypothetical protein K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
B Matrix
C MMC/PAM proteins
D PFDG_03656 hypothetical protein similar to mitochondrial import inner membrane translocase K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D PFDG_01601 chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK
D PFDG_03687 chaperone K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Other matrix factors
D PFDG_02249 hypothetical protein similar to mitochondrial processing peptidase alpha subunit K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D PFDG_00526 hypothetical protein K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D PFDG_00671 chaperonin CPN60-2, mitochondrial precursor K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D PFDG_03869 hypothetical protein K04078 groES; chaperonin GroES
D PFDG_01232 DnaJ protein K03686 dnaJ; molecular chaperone DnaJ
D PFDG_03191 conserved hypothetical protein K17808 ZIM17; mitochondrial protein import protein ZIM17
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D PFDG_02476 hypothetical protein similar to small GTP-binding protein domain K02355 fusA; elongation factor G
D PFDG_02044 hypothetical protein K02355 fusA; elongation factor G
C Nuclear respiratory factors
C Coactivators
C Proteins involved in Fe-S cluster biogenesis
D PFDG_00130 hypothetical protein similar to cysteine desulphurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D PFDG_05261 predicted protein K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D PFDG_04145 iron sulfur cluster assembly protein 2, mitochondrial precursor K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D PFDG_02656 hypothetical protein similar to adrenodoxin reductase K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D PFDG_01601 chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK
D PFDG_02204 hypothetical protein K04082 hscB; molecular chaperone HscB
D PFDG_03847 hypothetical protein K07390 grxD; monothiol glutaredoxin
D PFDG_04331 predicted protein K22063 ISCA1; iron-sulfur cluster assembly 1
D PFDG_00059 hypothetical protein K22072 ISCA2; iron-sulfur cluster assembly 2
D PFDG_04210 hypothetical protein K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
C Other regulator of mitochondrial biogenesis
D PFDG_03587 conserved hypothetical protein K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D PFDG_03906 conserved hypothetical protein K26537 UXT; protein UXT
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
C Complex-II assembly factors
C Complex-III assembly factors
D PFDG_00238 hypothetical protein K08900 BCS1; mitochondrial chaperone BCS1
C Complex-IV assembly factors
D PFDG_01783 conserved hypothetical protein K18171 CMC1; COX assembly mitochondrial protein 1
D PFDG_00508 conserved hypothetical protein K18178 COA5; cytochrome c oxidase assembly factor 5
D PFDG_02623 hypothetical protein similar to cytochrome c oxidase assembly protein K02257 COX10; heme o synthase [EC:2.5.1.141]
D PFDG_00674 hypothetical protein K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D PFDG_00587 hypothetical protein similar to cytochrome c oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D PFDG_00695 hypothetical protein similar to copper chaperone COX17-1 K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D PFDG_00034 hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D PFDG_01855 hypothetical protein K07152 SCO1; protein SCO1
D PFDG_05056 conserved hypothetical protein K07152 SCO1; protein SCO1
C Complex-V assembly factors
D PFDG_01276 hypothetical protein K07555 ATPeAF1; ATP synthase mitochondrial F1 complex assembly factor 1
B Mitochondrial dynamics
C Fission and Fusion factors
D PFDG_03503 dynamin protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Actin cytoskeleton organization
D PFDG_00278 conserved hypothetical protein K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D PFDG_00662 mitochondrial prohibitin complex protein 2 K17081 PHB2; prohibitin 2
C Retention of mitochondria
D PFDG_03503 dynamin protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Morphogenesis factors
D PFDG_04196 conserved hypothetical protein K17408 DAP3; small subunit ribosomal protein S29
B Mitophagy factors
C Autophagy-related proteins
D PFDG_03807 predicted protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D PFDG_01805 hypothetical protein similar to autophagy 8i K08341 GABARAP; GABA(A) receptor-associated protein
D PFDG_03480 predicted protein K08336 ATG12; ubiquitin-like protein ATG12
C Parkin-dependent mechanism factors
D PFDG_03978 conserved hypothetical protein K19513 CLEC16A; protein CLEC16A
C Parkin-independent mechanism factors
D PFDG_01851 heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
C Other mitophagy factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024