+D
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Transfer RNA Biogenesis - Pseudomonas protegens Pf-5
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D PFL_3322 ribonuclease T2 family protein K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D PFL_5656 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D PFL_2304 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D PFL_2049 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D PFL_1256 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D PFL_5321 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D PFL_5439 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PFL_4844 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D PFL_3913 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D PFL_0439 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D PFL_1138 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D PFL_4767 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D PFL_4506 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D PFL_1766 conserved hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D PFL_6184 thrS_2; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PFL_2111 thrS_1; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PFL_3876 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D PFL_3912 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D PFL_1063 valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D PFL_4953 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D PFL_2115 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D PFL_2116 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D PFL_5607 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D PFL_5087 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D PFL_0412 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D PFL_5616 histidine triad domain protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D PFL_5017 histidine triad domain protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D PFL_5849 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D PFL_1242 methyltransferase, YaeB/AF_0241 family K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D PFL_2071 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D PFL_0846 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D PFL_1203 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D PFL_4965 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D PFL_4152 aminotransferase, class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D PFL_0025 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D PFL_0565 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D PFL_6229 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D PFL_6226 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D PFL_2278 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D PFL_0298 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D PFL_6307 rnpB; Bacterial RNase P class A K01978 rnpB; M1 RNA
B 3'processing and CCA adding factors
C 3'processing factors
D PFL_4856 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D PFL_6059 rph; tRNA nucleotidyltransferase K00989 rph; ribonuclease PH [EC:2.7.7.56]
D PFL_1495 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D PFL_3322 ribonuclease T2 family protein K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D PFL_5656 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D PFL_2304 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D PFL_5848 RNA 2'-phosphotransferase, KptA family K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D PFL_5344 ATP-binding cassette protein, ChvD family K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D PFL_5439 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PFL_1256 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D PFL_5607 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D PFL_5087 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D PFL_6184 thrS_2; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PFL_2111 thrS_1; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PFL_5321 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D PFL_1138 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D PFL_4506 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D PFL_1766 conserved hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D PFL_1063 valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D PFL_4844 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D PFL_3876 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D PFL_4767 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D PFL_0014 glyQ; glycine--tRNA ligase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D PFL_0013 glyS; glycine--tRNA ligase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D PFL_3912 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D PFL_2049 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D PFL_3913 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D PFL_0439 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D PFL_2115 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D PFL_2116 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D PFL_4953 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D PFL_5271 gluQ; glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D PFL_0412 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D PFL_4866 ybaK; Cys-tRNA[Pro] and Cys-tRNA[Cys] deacylase YbaK K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D PFL_0151 putative YbaK/prolyl-tRNA synthetases associated domain protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
D PFL_5205 YbaK/prolyl-tRNA synthetase-associated domain protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D PFL_4928 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D PFL_1975 dusA; tRNA dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D PFL_0668 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D PFL_2059 dusC; tRNA-dihydrouridine synthase C K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D PFL_5432 miaB; tRNA-I(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D PFL_4926 cmoA; tRNA (cmo5U34)-methyltransferase CmoA K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D PFL_2762 methyltransferase domain protein K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D PFL_4927 cmoB; tRNA (mo5U34)-methyltransferase CmoB K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D PFL_0683 smtA; SmtA protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D PFL_5373 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D PFL_5849 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D PFL_1096 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D PFL_6229 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D PFL_4968 trmJ; tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D PFL_2370 conserved hypothetical protein K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]
D PFL_0375 RNA methyltransferase, TrmH family, group 2 K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D PFL_1242 methyltransferase, YaeB/AF_0241 family K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D PFL_2071 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D PFL_0846 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D PFL_1203 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D PFL_4382 rluA; ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D PFL_4223 RNA pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D PFL_3891 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D PFL_4463 ttcA; putative tRNA 2-thiocytidine biosynthesis protein TtcA K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D PFL_1931 tusA; sulfurtransferase TusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D PFL_1453 conserved hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D PFL_3871 tusB; sulfur relay protein TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D PFL_3870 tusC; sulfur relay protein TusC K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D PFL_3869 tusD; sulfur relay protein TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D PFL_3872 tusE; sulfurtransferase K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D PFL_4963 iscA; iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D PFL_4965 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D PFL_4152 aminotransferase, class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D PFL_1444 ygfZ; folate-binding protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D PFL_6226 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D PFL_0565 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D PFL_2636 miaE; tRNA-(ms[2]io[6]A)-hydroxylase K06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]
D PFL_4332 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D PFL_4975 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D PFL_4754 protein ExsB K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D PFL_5031 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D PFL_4019 queD; queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D PFL_4755 radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D PFL_1967 queF; queuine synthase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D PFL_0560 putative iron-sulfur cluster-binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D PFL_2278 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D PFL_2279 selU; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D PFL_4974 tgt; tRNA-guanine transglycosylase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D PFL_0387 thiI; thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D PFL_1193 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D PFL_1149 yeaZ; peptidase, M22 family K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D PFL_0025 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D PFL_5660 gcp; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D PFL_0562 ATPase, YjeE family K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D PFL_1167 ThiF family protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C PFL_0577 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C PFL_0848 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024