+F Repair protein KO
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DNA Repair and Recombination Proteins - Pyrolobus fumarii
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Pyrfu_1595 methylated-DNA/protein-cysteinemethyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Pyrfu_1939 HhH-GPD family protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
E Pyrfu_0182 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
E Pyrfu_1903 Proliferating cell nuclear antigen, PCNA K04802 PCNA; proliferating cell nuclear antigen
E Pyrfu_1696 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
E Pyrfu_0109 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E Pyrfu_1977 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E Pyrfu_0780 helicase c2 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
E Pyrfu_1794 ERCC4 domain protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E Pyrfu_1303 ERCC4 domain protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E Pyrfu_1977 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
E Pyrfu_0182 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
E Pyrfu_1903 Proliferating cell nuclear antigen, PCNA K04802 PCNA; proliferating cell nuclear antigen
E Pyrfu_1696 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
E Pyrfu_1977 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
D Pyrfu_0182 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D Pyrfu_1903 Proliferating cell nuclear antigen, PCNA K04802 PCNA; proliferating cell nuclear antigen
D Pyrfu_1696 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Pyrfu_0774 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Pyrfu_0817 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Pyrfu_0634 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Pyrfu_1595 methylated-DNA/protein-cysteinemethyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Pyrfu_0137 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Pyrfu_1939 HhH-GPD family protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Pyrfu_0664 Xylose isomerase domain-containing protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E Pyrfu_0203 Deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Pyrfu_1608 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Pyrfu_1550 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Pyrfu_1551 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
E Pyrfu_0500 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Pyrfu_0974 DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
E Pyrfu_1726 Resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
E Pyrfu_1550 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Pyrfu_1551 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
E Pyrfu_1552 HerA-ATP synthase with barrel domain K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Pyrfu_1946 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Pyrfu_0303 DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Pyrfu_0966 DEAD/DEAH box helicase domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Pyrfu_1637 DEAD/DEAH box helicase domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Pyrfu_0774 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Pyrfu_0817 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Pyrfu_0634 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Pyrfu_0579 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D Pyrfu_1355 protein of unknown function DUF650 K22585 nreA; DNA repair protein NreA
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024