+C Two-component system KO #

  Two-Component System - Pseudomonas simiae PCL1751

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AOmpR family B PhoR-PhoB (phosphate starvation response) C PF1751_v1c54500 phoR; phosphate regulon sensor kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] C PF1751_v1c54490 phoB; phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB B SenX3-RegX3 (phosphate starvation response) B PhoQ-PhoP (magnesium transport) C PF1751_v1c42270 phoQ; sensor protein PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3] C PF1751_v1c42280 phoP; DNA-binding response regulator PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP B EnvZ-OmpR (osmotic stress response) C PF1751_v1c02290 envZ; osmolarity-sensing histidine-kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3] C PF1751_v1c02280 ompR; DNA-binding response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR B RstB-RstA C PF1751_v1c42310 sensor histidine kinase K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3] C PF1751_v1c42320 DNA-binding response regulator K07661 rstA; two-component system, OmpR family, response regulator RstA B CpxA-CpxR (envelope stress response) C PF1751_v1c43780 DNA-binding response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR B CssS-CssR (secretion stress response) B CreC-CreB (phosphate regulation) C PF1751_v1c50680 creC; sensor histidine kinase CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] C PF1751_v1c50690 creB; DNA-binding response regulator CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB B BaeS-BaeR (envelope stress response) C PF1751_v1c35690 sensor histidine kinase K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3] C PF1751_v1c35700 two-component system response regulator K07664 baeR; two-component system, OmpR family, response regulator BaeR B BasS-BasR (antimicrobial peptide resistance) B CusS-CusR (copper tolerance) C PF1751_v1c06590 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] C PF1751_v1c09160 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] C PF1751_v1c15600 copS; copper sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] C PF1751_v1c36790 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] C PF1751_v1c01880 transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR C PF1751_v1c06600 czcR; transcriptional activator protein CzcR K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR C PF1751_v1c09170 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR C PF1751_v1c15610 copR; DNA-binding copper response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR C PF1751_v1c36780 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR B QseC-QseB (quorum sensing) C PF1751_v1c26460 sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3] C PF1751_v1c38760 sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3] C PF1751_v1c26470 response regulator protein K07666 qseB; two-component system, OmpR family, response regulator QseB C PF1751_v1c38770 DNA-binding response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB B KdpD-KdpE (potassium transport) C PF1751_v1c16480 kdpD; two-component system sensor kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] C PF1751_v1c16490 kdpE; two-component system response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE B TorS-TorR (TMAO respiration) B ArcB-ArcA (anoxic redox control) B TctE-TctD (tricarboxylic acid transport) C PF1751_v1c13900 sensor histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3] C PF1751_v1c13890 tctD; DNA-binding response regulator K07774 tctD; two-component system, OmpR family, response regulator TctD B ResE-ResD (aerobic and anaerobic respiration) B VicK-VicR (cell wall metabolism) B MprB-MprA (maintenance of persistent infection) B MtrB-MtrA (osmotic stress response) B PrrB-PrrA (intracellular multiplication) B TrcS-TrcR B NrsS-NrsR (nickel tolerance) B ManS-ManR (manganese homeostasis) B NblS-NblR (photosynthesis) B SasA-RpaAB (circadian timing mediating) B SaeS-SaeR (staphylococcal virulence regulation) B BceS-BceR (bacitracin transport) B BraS-BraR (bacitracin transport) B GraS-GraR (cationic antimicrobial peptide transport) B YxdK-YxdJ (antimicrobial peptide response) B ChvG-ChvI (acidity sensing) B CiaH-CiaR B ParS-ParR (polymyxin-adaptive resistance) C PF1751_v1c29120 sensor protein RstB K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3] C PF1751_v1c29130 transcriptional regulatory protein RstA K18073 parR; two-component system, OmpR family, response regulator ParR B AdeS-AdeR C PF1751_v1c20320 sensor histidine kinase K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3] C PF1751_v1c20330 hypothetical protein K18144 adeR; two-component system, OmpR family, response regulator AdeR B VanS-VanR (VanB type vancomycin resistance) B VanS-VanR (VanE type vancomycin resistance) B VanS-VanR (actinomycete type vancomycin resistance) B ArlS-ArlR (virulence regulation) B Ihk-Irr (virulence regulation) B PfeS-PfeR (enterobactin-dependent iron acquisition) C PF1751_v1c31920 sensor histidine kinase K19609 pfeS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3] C PF1751_v1c31930 DNA-binding response regulator K19610 pfeR; two-component system, OmpR family, response regulator PfeR B NisK-NisR (lantibiotic biosynthesis) B Unclassified C PF1751_v1c23850 rpeA; sensor histidine kinase RpeA K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C PF1751_v1c35380 putative two-component system sensor kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C PF1751_v1c09750 hypothetical protein K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c12680 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c17970 DNA-binding response regulator, OmpR family K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c19420 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c22280 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c23840 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c31230 two component transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c35390 putative two-component system regulator K02483 K02483; two-component system, OmpR family, response regulator C PF1751_v1c44540 gltR; DNA-binding response regulator GltR K02483 K02483; two-component system, OmpR family, response regulator # ANarL family B NarX-NarL (nitrate respiration) C PF1751_v1c30690 narX; protein NarX K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3] C PF1751_v1c30700 narL; protein NarL K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL B NarQ-NarP (nitrate respiration) B UhpB-UhpA (hexose phosphates uptake) C PF1751_v1c34090 sensor histidine kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3] B FusK-FusR (virulence regulation) B RcsC-RcsD-RcsB (capsule synthesis) C PF1751_v1c33060 sensor histidine kinase/response regulator K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3] C PF1751_v1c33080 sensor histidine kinase/response regulator K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3] C PF1751_v1c09760 LuxR family DNA-binding response regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB C PF1751_v1c33090 LuxR family DNA-binding response regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB B BarA-UvrY (central carbon metabolism) C PF1751_v1c31940 gacS; sensor protein GacS K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3] C PF1751_v1c20180 gacA; response regulator GacA K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY C PF1751_v1c34080 LuxR family transcriptional regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY B ComP-ComA (competence) B EvgS-EvgA (acid and drug tolerance) C PF1751_v1c17060 sensory box histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] C PF1751_v1c20040 sensory box histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] C PF1751_v1c11080 LuxR family DNA-binding response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA C PF1751_v1c17070 LuxR family DNA-binding response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA C PF1751_v1c20030 LuxR family DNA-binding response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA B DegS-DegU (multicellular behavior control) B DesK-DesR (membrane lipid fluidity regulation) B VraS-VraR (cell-wall peptidoglycan synthesis) B LiaS-LiaR (cell wall stress response) B DevS-DevR (redox response) B NreB-NreC (dissimilatory nitrate/nitrite reduction) B YdfH-YdfI B SalK-SalR B PprA–PprB (biofilm formation) C PF1751_v1c05970 two-component system sensor kinase K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3] C PF1751_v1c06000 two component LuxR family transcriptional regulator K27077 pprB; two-component system, NarL family, response regulator PprB B Unclassified # ASpo family B KinABCDE-Spo0FA (sporulation control) # ACitB family B CitA-CitB (citrate fermentation) B CitS-CitT (magnesium-citrate transport) B DcuS-DcuR (C4-dicarboxylate metabolism) B DctS-DctR (C4-dicarboxylate transport) B MalK-MalR (malate transport) B Unclassified # ALytTR family B LysS-LysR B AlgZ-AlgR (alginate production) C PF1751_v1c53430 algR; DNA-binding response regulator AlgR K08083 algR; two-component system, LytTR family, response regulator AlgR B NatK-NatR (sodium extrusion) B AgrC-AgrA (exoprotein synthesis) B AgrC2-AgrA2 (virulence regulation) B ComD-ComE (competence) B BtsS-BtsR (pyruvate reutilization) B PyrS-PyrR (pyruvate reutilization) B Unclassified # ANtrC family B GlnL-GlnG (nitrogen regulation) C PF1751_v1c03180 glnL; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] C PF1751_v1c03170 glnG; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG B NtrY-NtrX (nitrogen regulation) B HydH-HydG (metal tolerance) C PF1751_v1c46880 cbrB; two-component response regulator CbrB K07713 zraR; two-component system, NtrC family, response regulator HydG B AtoS-AtoC (cPHB biosynthesis) B PilS-PilR (type 4 fimbriae synthesis) B GlrK-GlrR (amino sugar metabolism) B PgtB-PgtA (phosphoglycerate transport) B DctB-DctD (C4-dicarboxylate transport) C PF1751_v1c02540 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3] C PF1751_v1c44460 dctB; C4-dicarboxylate transport sensor protein DctB K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3] C PF1751_v1c02530 sigma-54 dependent DNA-binding response regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD C PF1751_v1c44470 dctD; C4-dicarboxylate transport transcriptional regulatory protein DctD K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD B KinB-AlgB (alginate production) C PF1751_v1c00880 kinB; alginate biosynthesis sensor protein KinB K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3] C PF1751_v1c00890 algB; alginate biosynthesis transcriptional regulatory protein K11384 algB; two-component system, NtrC family, response regulator AlgB B HupT-HupR (hydrogenase synthesis regulation) B Unclassified C PF1751_v1c10620 response regulator/sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] C PF1751_v1c10630 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] # ACheA family B CheA-CheYBV (chemotaxis) C PF1751_v1c39080 cheA; chemotaxis sensor histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] C PF1751_v1c39100 cheY; chemotaxis regulator CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C PF1751_v1c27090 cheB; chemotaxis response regulator CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] C PF1751_v1c39070 cheB; chemotaxis response regulator CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] C PF1751_v1c09240 chemotaxis protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV C PF1751_v1c38960 CheW-like domain protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV C PF1751_v1c42400 cheV; chemotaxis response regulator CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV B ChpA-ChpB/PilGH (chemosensory) C PF1751_v1c51670 chpA; sensor histidine kinase/response regulator ChpA K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator) C PF1751_v1c51710 pilG; type IV pilus response regulator PilG K02657 pilG; twitching motility two-component system response regulator PilG C PF1751_v1c51700 pilH; type IV pilus response regulator PilH K02658 pilH; twitching motility two-component system response regulator PilH B PixL-PixGH (positive phototaxis) B WspE-WspRF (chemosensory) C PF1751_v1c11720 wspE; chemotaxis sensor histidine kinase and response regulator WspE K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE C PF1751_v1c11740 wspR; chemotaxis response regulator WspR K11444 wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65] C PF1751_v1c11730 wspF; chemotaxis response regulator WspF K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61] B Cph1-Rcp1 (light response) C PF1751_v1c45730 bphP; bacteriophytochrome histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3] # ACell cycle family B PleC-PleD (cell fate control) B CckA-CtrA/CpdR (cell cycle control) C PF1751_v1c27070 response regulator K13589 cpdR; two-component system, cell cycle response regulator CpdR B Hk1-Rrp1 (glycerol uptake and utilization) # ALux family B LuxQN/CqsS-LuxU-LuxO (quorum sensing) # ALuxR family B DctS-DctR (C4-dicarboxylate transport) B TtrS-TtrR (tetrathionate respiration) B FixL-FixJ (nitrogen fixation) B SsrA-SsrB # AOther families B FlrB-FlrC (polar flagellar synthesis) C PF1751_v1c39350 fleS; sensory box histidine kinase FleS K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3] C PF1751_v1c39340 fleR; sigma-54 dependent DNA-binding response regulator FleR K10943 flrC; two-component system, response regulator FlrC B AauS-AauR (acidic amino acids utilization) C PF1751_v1c10870 two-component system, sensor kinase K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3] C PF1751_v1c10860 hypothetical protein K17061 aauR; two-component system, response regulator AauR B SLN1-YPD1-SSK1/SKN7 (osmosensing) B RpfC-RpfG (cell-to-cell signaling) B GlnK-GlnL (glutamine utilization) B HspS-HspR (hexose phosphates uptake) B YesM-YesN B CikA B RegB-RegA (redox response) C PF1751_v1c07990 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3] C PF1751_v1c08000 DNA-binding response regulator, Fis family K15012 regA; two-component system, response regulator RegA B FitF-FitH (insecticidal toxin regulation) B PhcS-PhcRQ B SagS-HptB-HsbR (swarming activity and biofilm formation) C PF1751_v1c17030 sensor histidine kinase/response regulator K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3] C PF1751_v1c17840 sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] C PF1751_v1c34160 sensor kinase protein RcsC K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3] C PF1751_v1c39250 Hpt domain-containing protein K20976 hptB; histidine phosphotransfer protein HptB C PF1751_v1c39260 response regulator K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator B PdtaS-PdtaR B NasS-NasT C PF1751_v1c41160 nasS; nitrate-binding protein NasS K22067 nasS; two-component system, oxyanion-binding sensor C PF1751_v1c41170 nasT; response regulator NasT K07183 nasT; two-component system, response regulator / RNA-binding antiterminator B Unclassified C PF1751_v1c48140 ladS; sensor histidine kinase/response regulator K20971 ladS; two-component system, sensor histidine kinase LadS C PF1751_v1c05720 retS; sensor histidine kinase/response regulator RetS K20972 retS; two-component system, sensor histidine kinase RetS ! #
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#Last updated: October 8, 2024