+C Two-component system KO
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Two-Component System - Paenibacillus lentus
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C EIM92_19525 HAMP domain-containing histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C EIM92_06105 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C EIM92_19520 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C EIM92_18870 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C EIM92_09790 histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
C EIM92_14050 HAMP domain-containing protein K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
C EIM92_14045 DNA-binding response regulator K07775 resD; two-component system, OmpR family, response regulator ResD
B VicK-VicR (cell wall metabolism)
C EIM92_04905 walK; cell wall metabolism sensor histidine kinase WalK K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
C EIM92_04900 DNA-binding response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR
B MprB-MprA (maintenance of persistent infection)
C EIM92_20080 DNA-binding response regulator K07669 mprA; two-component system, OmpR family, response regulator MprA
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
C EIM92_05375 sensor histidine kinase K11629 bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]
C EIM92_05380 DNA-binding response regulator K11630 bceR; two-component system, OmpR family, bacitracin resistance response regulator BceR
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
C EIM92_14505 sensor histidine kinase K11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]
C EIM92_14500 DNA-binding response regulator K11634 yxdJ; two-component system, OmpR family, response regulator YxdJ
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
C EIM92_19805 DNA-binding response regulator K18349 vanRC; two-component system, OmpR family, response regulator VanR
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
C EIM92_00310 sensor histidine kinase K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
C EIM92_00305 DNA-binding response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR
B Unclassified
C EIM92_07910 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C EIM92_20075 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C EIM92_07915 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C EIM92_05050 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C EIM92_15535 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C EIM92_11210 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
C EIM92_14860 sensor histidine kinase K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
C EIM92_06540 histidine kinase K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
C EIM92_06545 DNA-binding response regulator K07692 degU; two-component system, NarL family, response regulator DegU
B DesK-DesR (membrane lipid fluidity regulation)
C EIM92_08950 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
C EIM92_21845 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
C EIM92_08955 DNA-binding response regulator K07693 desR; two-component system, NarL family, response regulator DesR
C EIM92_21840 DNA-binding response regulator K07693 desR; two-component system, NarL family, response regulator DesR
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
C EIM92_08480 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
C EIM92_20095 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
C EIM92_08485 DNA-binding response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR
C EIM92_20090 DNA-binding response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
C EIM92_09430 PAS domain-containing protein K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
C EIM92_09435 DNA-binding response regulator K07696 nreC; two-component system, NarL family, response regulator NreC
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C EIM92_09260 sensor histidine kinase K07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]
C EIM92_04205 PAS domain S-box protein K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C EIM92_04060 response regulator K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C EIM92_13685 spo0A; sporulation transcription factor Spo0A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
C EIM92_12195 dcuS; two-component system sensor histidine kinase DcuS K11614 yufL; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]
C EIM92_12200 response regulator K11615 malR; two-component system, CitB family, response regulator MalR
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C EIM92_17230 response regulator K02477 K02477; two-component system, LytTR family, response regulator
C EIM92_12895 response regulator K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C EIM92_17735 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C EIM92_17795 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C EIM92_17740 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C EIM92_18635 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
C EIM92_05765 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_11090 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_02590 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_02655 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_06740 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_11240 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_11290 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_09590 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_02695 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_02845 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_01930 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_11655 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_11765 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_10665 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_09100 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_09180 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_05420 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_05455 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_22095 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_02985 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_03055 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_11920 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_03290 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_07655 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_07775 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_07820 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_21310 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_13455 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_23410 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_11030 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_21540 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C EIM92_05770 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_11035 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_11095 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_15365 helix-turn-helix domain-containing protein K07720 yesN; two-component system, response regulator YesN
C EIM92_21545 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_02585 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_02650 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_06750 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_11245 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_11295 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_09585 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_23400 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_02690 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_01935 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_11650 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_11745 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_10670 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_09095 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_09185 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_13425 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_05415 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_05450 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_05460 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_22090 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_02990 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_03060 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_11925 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_03295 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_07660 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_07780 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_07825 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_21315 response regulator K07720 yesN; two-component system, response regulator YesN
C EIM92_02840 response regulator K07720 yesN; two-component system, response regulator YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C EIM92_08150 hybrid sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C EIM92_14915 response regulator K19694 chiS; two-component system, sensor histidine kinase ChiS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023