+C Two-component system KO #

  Two-Component System - Paenibacillus lentus

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AOmpR family B PhoR-PhoB (phosphate starvation response) C EIM92_19525 HAMP domain-containing histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] C EIM92_06105 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP C EIM92_19520 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP C EIM92_18870 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP B SenX3-RegX3 (phosphate starvation response) B PhoQ-PhoP (magnesium transport) B EnvZ-OmpR (osmotic stress response) B RstB-RstA B CpxA-CpxR (envelope stress response) B CssS-CssR (secretion stress response) B CreC-CreB (phosphate regulation) B BaeS-BaeR (envelope stress response) B BasS-BasR (antimicrobial peptide resistance) B CusS-CusR (copper tolerance) B QseC-QseB (quorum sensing) B KdpD-KdpE (potassium transport) C EIM92_09790 histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] B TorS-TorR (TMAO respiration) B ArcB-ArcA (anoxic redox control) B TctE-TctD (tricarboxylic acid transport) B ResE-ResD (aerobic and anaerobic respiration) C EIM92_14050 HAMP domain-containing protein K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3] C EIM92_14045 DNA-binding response regulator K07775 resD; two-component system, OmpR family, response regulator ResD B VicK-VicR (cell wall metabolism) C EIM92_04905 walK; cell wall metabolism sensor histidine kinase WalK K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] C EIM92_04900 DNA-binding response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR B MprB-MprA (maintenance of persistent infection) C EIM92_20080 DNA-binding response regulator K07669 mprA; two-component system, OmpR family, response regulator MprA B MtrB-MtrA (osmotic stress response) B PrrB-PrrA (intracellular multiplication) B TrcS-TrcR B NrsS-NrsR (nickel tolerance) B ManS-ManR (manganese homeostasis) B NblS-NblR (photosynthesis) B SasA-RpaAB (circadian timing mediating) B SaeS-SaeR (staphylococcal virulence regulation) B BceS-BceR (bacitracin transport) C EIM92_05375 sensor histidine kinase K11629 bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3] C EIM92_05380 DNA-binding response regulator K11630 bceR; two-component system, OmpR family, bacitracin resistance response regulator BceR B BraS-BraR (bacitracin transport) B GraS-GraR (cationic antimicrobial peptide transport) B YxdK-YxdJ (antimicrobial peptide response) C EIM92_14505 sensor histidine kinase K11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3] C EIM92_14500 DNA-binding response regulator K11634 yxdJ; two-component system, OmpR family, response regulator YxdJ B ChvG-ChvI (acidity sensing) B CiaH-CiaR B ParS-ParR (polymyxin-adaptive resistance) B AdeS-AdeR B VanS-VanR (VanB type vancomycin resistance) B VanS-VanR (VanE type vancomycin resistance) C EIM92_19805 DNA-binding response regulator K18349 vanRC; two-component system, OmpR family, response regulator VanR B VanS-VanR (actinomycete type vancomycin resistance) B ArlS-ArlR (virulence regulation) B Ihk-Irr (virulence regulation) B PfeS-PfeR (enterobactin-dependent iron acquisition) B NisK-NisR (lantibiotic biosynthesis) C EIM92_00310 sensor histidine kinase K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] C EIM92_00305 DNA-binding response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR B Unclassified C EIM92_07910 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C EIM92_20075 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C EIM92_07915 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C EIM92_05050 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C EIM92_15535 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C EIM92_11210 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator # ANarL family B NarX-NarL (nitrate respiration) B NarQ-NarP (nitrate respiration) C EIM92_14860 sensor histidine kinase K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3] B UhpB-UhpA (hexose phosphates uptake) B FusK-FusR (virulence regulation) B RcsC-RcsD-RcsB (capsule synthesis) B BarA-UvrY (central carbon metabolism) B ComP-ComA (competence) B EvgS-EvgA (acid and drug tolerance) B DegS-DegU (multicellular behavior control) C EIM92_06540 histidine kinase K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3] C EIM92_06545 DNA-binding response regulator K07692 degU; two-component system, NarL family, response regulator DegU B DesK-DesR (membrane lipid fluidity regulation) C EIM92_08950 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] C EIM92_21845 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] C EIM92_08955 DNA-binding response regulator K07693 desR; two-component system, NarL family, response regulator DesR C EIM92_21840 DNA-binding response regulator K07693 desR; two-component system, NarL family, response regulator DesR B VraS-VraR (cell-wall peptidoglycan synthesis) B LiaS-LiaR (cell wall stress response) C EIM92_08480 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] C EIM92_20095 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] C EIM92_08485 DNA-binding response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR C EIM92_20090 DNA-binding response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR B DevS-DevR (redox response) B NreB-NreC (dissimilatory nitrate/nitrite reduction) C EIM92_09430 PAS domain-containing protein K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3] C EIM92_09435 DNA-binding response regulator K07696 nreC; two-component system, NarL family, response regulator NreC B YdfH-YdfI B SalK-SalR B PprA–PprB (biofilm formation) B Unclassified # ASpo family B KinABCDE-Spo0FA (sporulation control) C EIM92_09260 sensor histidine kinase K07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3] C EIM92_04205 PAS domain S-box protein K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3] C EIM92_04060 response regulator K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F C EIM92_13685 spo0A; sporulation transcription factor Spo0A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A # ACitB family B CitA-CitB (citrate fermentation) B CitS-CitT (magnesium-citrate transport) B DcuS-DcuR (C4-dicarboxylate metabolism) B DctS-DctR (C4-dicarboxylate transport) B MalK-MalR (malate transport) C EIM92_12195 dcuS; two-component system sensor histidine kinase DcuS K11614 yufL; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3] C EIM92_12200 response regulator K11615 malR; two-component system, CitB family, response regulator MalR B Unclassified # ALytTR family B LysS-LysR B AlgZ-AlgR (alginate production) B NatK-NatR (sodium extrusion) B AgrC-AgrA (exoprotein synthesis) B AgrC2-AgrA2 (virulence regulation) B ComD-ComE (competence) B Unclassified C EIM92_17230 response regulator K02477 K02477; two-component system, LytTR family, response regulator C EIM92_12895 response regulator K02477 K02477; two-component system, LytTR family, response regulator # ANtrC family B GlnL-GlnG (nitrogen regulation) B NtrY-NtrX (nitrogen regulation) B HydH-HydG (metal tolerance) B AtoS-AtoC (cPHB biosynthesis) B PilS-PilR (type 4 fimbriae synthesis) B GlrK-GlrR (amino sugar metabolism) B PgtB-PgtA (phosphoglycerate transport) B DctB-DctD (C4-dicarboxylate transport) B KinB-AlgB (alginate production) B HupT-HupR (hydrogenase synthesis regulation) B Unclassified # ACheA family B CheA-CheYBV (chemotaxis) C EIM92_17735 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] C EIM92_17795 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C EIM92_17740 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] C EIM92_18635 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] B ChpA-ChpB/PilGH (chemosensory) B PixL-PixGH (positive phototaxis) B WspE-WspRF (chemosensory) B Cph1-Rcp1 (light response) # ACell cycle family B PleC-PleD (cell fate control) B CckA-CtrA/CpdR (cell cycle control) B Hk1-Rrp1 (glycerol uptake and utilization) # ALux family B LuxQN/CqsS-LuxU-LuxO (quorum sensing) # ALuxR family B DctS-DctR (C4-dicarboxylate transport) B TtrS-TtrR (tetrathionate respiration) B FixL-FixJ (nitrogen fixation) B SsrA-SsrB # AOther families B FlrB-FlrC (polar flagellar synthesis) B AauS-AauR (acidic amino acids utilization) B SLN1-YPD1-SSK1/SKN7 (osmosensing) B RpfC-RpfG (cell-to-cell signaling) B GlnK-GlnL (glutamine utilization) B HspS-HspR (hexose phosphates uptake) B YesM-YesN C EIM92_05765 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_11090 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_02590 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_02655 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_06740 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_11240 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_11290 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_09590 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_02695 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_02845 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_01930 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_11655 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_11765 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_10665 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_09100 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_09180 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_05420 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_05455 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_22095 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_02985 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_03055 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_11920 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_03290 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_07655 HAMP domain-containing protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_07775 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_07820 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_21310 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_13455 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_23410 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_11030 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_21540 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C EIM92_05770 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_11035 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_11095 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_15365 helix-turn-helix domain-containing protein K07720 yesN; two-component system, response regulator YesN C EIM92_21545 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_02585 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_02650 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_06750 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_11245 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_11295 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_09585 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_23400 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_02690 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_01935 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_11650 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_11745 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_10670 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_09095 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_09185 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_13425 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_05415 DNA-binding response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_05450 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_05460 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_22090 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_02990 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_03060 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_11925 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_03295 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_07660 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_07780 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_07825 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_21315 response regulator K07720 yesN; two-component system, response regulator YesN C EIM92_02840 response regulator K07720 yesN; two-component system, response regulator YesN B CikA B RegB-RegA (redox response) B FitF-FitH (insecticidal toxin regulation) B PhcS-PhcRQ B SagS-HptB-HsbR (swarming activity and biofilm formation) C EIM92_08150 hybrid sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] B PdtaS-PdtaR B NasS-NasT B Unclassified C EIM92_14915 response regulator K19694 chiS; two-component system, sensor histidine kinase ChiS ! #
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#Last updated: December 14, 2023