+F Repair protein KO
#
DNA Repair and Recombination Proteins - Paucimonas lemoignei
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D NCTC10937_04383 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E NCTC10937_01316 ung; uracil-DNA glycosylase Ung K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E NCTC10937_04791 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E NCTC10937_00417 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E NCTC10937_04212 nth; endonuclease III/Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E NCTC10937_02651 Uvs006 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D NCTC10937_01104 mutT; putative mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC10937_02448 rppH_2; mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC10937_01151 mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC10937_00184 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D NCTC10937_02723 ada; AraC family transcriptional regulator K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D NCTC10937_01572 ogt_2; transcriptional regulator Ada / DNA-O6-methylguanine--protein-cysteine S-methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D NCTC10937_04383 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D NCTC10937_02559 alkB; alkylated DNA repair protein AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E NCTC10937_01316 ung; uracil-DNA glycosylase Ung K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E NCTC10937_04791 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E NCTC10937_00417 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E NCTC10937_00009 tag_1; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E NCTC10937_00383 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E NCTC10937_04212 nth; endonuclease III/Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E NCTC10937_00189 crc; Crc K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E NCTC10937_02486 xthA_2; exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E NCTC10937_02295 xthA_1; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E NCTC10937_01414 recJ; RecJ exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E NCTC10937_03748 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E NCTC10937_00438 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E NCTC10937_00091 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E NCTC10937_04840 uvrA_2; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E NCTC10937_02733 uvrA_1; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E NCTC10937_03331 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E NCTC10937_02765 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E NCTC10937_05227 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E NCTC10937_00091 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E NCTC10937_03748 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E NCTC10937_00438 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F NCTC10937_04875 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F NCTC10937_04874 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F NCTC10937_04844 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F NCTC10937_00194 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F NCTC10937_01957 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E NCTC10937_01501 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E NCTC10937_00753 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E NCTC10937_01246 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E NCTC10937_01373 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E NCTC10937_04811 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E NCTC10937_01482 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E NCTC10937_00002 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E NCTC10937_04250 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E NCTC10937_04776 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E NCTC10937_01715 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E NCTC10937_00543 polC_1; exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NCTC10937_03659 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NCTC10937_04744 polC_2; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NCTC10937_03734 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E NCTC10937_03748 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E NCTC10937_00438 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E NCTC10937_05227 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E NCTC10937_02984 ssb_1; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E NCTC10937_04838 ssb_2; Ssb K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E NCTC10937_04707 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E NCTC10937_04708 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E NCTC10937_04706 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E NCTC10937_01503 recA; recombinase A K03553 recA; recombination protein RecA
E NCTC10937_01535 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E NCTC10937_01536 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E NCTC10937_01534 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E NCTC10937_00599 priA; primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E NCTC10937_01246 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E NCTC10937_01789 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E NCTC10937_01790 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E NCTC10937_01503 recA; recombinase A K03553 recA; recombination protein RecA
E NCTC10937_00917 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E NCTC10937_00003 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
E NCTC10937_00203 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E NCTC10937_01414 recJ; RecJ exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E NCTC10937_01122 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E NCTC10937_03731 recR; RecR protein K06187 recR; recombination protein RecR
E NCTC10937_04533 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E NCTC10937_01611 rdgC; recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E NCTC10937_01535 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E NCTC10937_01536 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E NCTC10937_01534 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E NCTC10937_01789 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E NCTC10937_01790 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E NCTC10937_01253 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E NCTC10937_01897 KU domain protein K10979 ku; DNA end-binding protein Ku
E NCTC10937_02207 ligD; ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F NCTC10937_03987 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F NCTC10937_00004 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F NCTC10937_01947 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F NCTC10937_02730 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F NCTC10937_05174 hupA; DNA-binding protein HU, alpha subunit K05787 hupA; DNA-binding protein HU-alpha
F NCTC10937_04255 hupN; DNA-binding protein HU form N K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F NCTC10937_01414 recJ; RecJ exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F NCTC10937_01122 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F NCTC10937_03731 recR; RecR protein K06187 recR; recombination protein RecR
F NCTC10937_03748 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F NCTC10937_00438 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F NCTC10937_00841 fis; Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F NCTC10937_02123 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F NCTC10937_03980 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F NCTC10937_01246 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F NCTC10937_00240 recQ_1; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F NCTC10937_01671 recQ_2; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F NCTC10937_02632 recQ_3; ATP-dependent DNA helicase domain-containing protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F NCTC10937_04840 uvrA_2; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F NCTC10937_02733 uvrA_1; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F NCTC10937_03331 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D NCTC10937_01523 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D NCTC10937_03015 umuC; DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D NCTC10937_03016 umuD_1; putative prophage repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D NCTC10937_03144 umuD_2; putative prophage repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D NCTC10937_01503 recA; recombinase A K03553 recA; recombination protein RecA
D NCTC10937_02664 lexA_2; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D NCTC10937_01951 lexA_1; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D NCTC10937_04533 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D NCTC10937_02842 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D NCTC10937_02665 cell division inhibitor SulA K14160 imuA; protein ImuA
D NCTC10937_02666 DNA repair nucleotidyltransferase K14161 imuB; protein ImuB
D NCTC10937_02667 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D NCTC10937_02984 ssb_1; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC10937_04838 ssb_2; Ssb K03111 ssb; single-strand DNA-binding protein
D NCTC10937_01504 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D NCTC10937_00180 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D NCTC10937_04185 dinG; ATP-dependent helicase, ATP-dependent DNA helicase DinG domain-containing protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D NCTC10937_04835 recQ_4; ATP-dependent DNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D NCTC10937_04204 helicase domain-containing protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D NCTC10937_01104 mutT; putative mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC10937_02448 rppH_2; mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC10937_01151 mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D NCTC10937_00184 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D NCTC10937_04067 nrdA; ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D NCTC10937_04069 nrdB; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024