+C Two-component system KO
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Two-Component System - Paenibacillus larvae
%
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C ERIC2_c34180 phoR; alkaline phosphatase synthesis sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C ERIC2_c34170 phoP; alkaline phosphatase synthesis transcriptional regulatory protein PhoP K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C ERIC2_c03150 kdpD; sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
C ERIC2_c13200 resE1; sensor histidine kinase ResE K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
C ERIC2_c13190 resD2; transcriptional regulatory protein ResD K07775 resD; two-component system, OmpR family, response regulator ResD
B VicK-VicR (cell wall metabolism)
C ERIC2_c01600 yycG; sensor histidine kinase YycG K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
C ERIC2_c01590 walR; transcriptional regulatory protein WalR K07668 vicR; two-component system, OmpR family, response regulator VicR
B MprB-MprA (maintenance of persistent infection)
C ERIC2_c35150 mprA; response regulator MprA K07669 mprA; two-component system, OmpR family, response regulator MprA
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
C ERIC2_c37300 resE2; sensor histidine kinase ResE K18345 vanSB; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
C ERIC2_c06220 ykoH; sensor histidine kinase YkoH K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
C ERIC2_c06230 arlR; response regulator ArlR K18941 arlR; two-component system, OmpR family, response regulator ArlR
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C ERIC2_c35140 sensory transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C ERIC2_c17460 Two-component response regulator YkoH-like protein K02483 K02483; two-component system, OmpR family, response regulator
C ERIC2_c30600 yvcP; putative transcriptional regulatory protein YvcP K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
C ERIC2_c36310 response regulator receiver domain protein K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
C ERIC2_c34460 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein K07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
C ERIC2_c00900 degS; sensor protein DegS K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
C ERIC2_c00910 degU; transcriptional regulatory protein DegU K07692 degU; two-component system, NarL family, response regulator DegU
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
C ERIC2_c30670 liaS1; sensor histidine kinase LiaS K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
C ERIC2_c35180 liaS2; sensor histidine kinase LiaS K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
C ERIC2_c35170 liaR2; transcriptional regulatory protein LiaR K11618 liaR; two-component system, NarL family, response regulator LiaR
C ERIC2_c30660 liaR1; transcriptional regulatory protein LiaR K11618 liaR; two-component system, NarL family, response regulator LiaR
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
C ERIC2_c40670 nreB; oxygen sensor histidine kinase NreB K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
C ERIC2_c40660 nreC; oxygen regulatory protein NreC K07696 nreC; two-component system, NarL family, response regulator NreC
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C ERIC2_c06530 sporulation kinase K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
C ERIC2_c29390 kinE1; sporulation kinase E K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
C ERIC2_c34750 kinE2; sporulation kinase E K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C ERIC2_c38940 kinE3; sporulation kinase E K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C ERIC2_c03070 Two-component sensor histidine kinase-like protein K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C ERIC2_c39000 spo0F; sporulation initiation phosphotransferase F K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C ERIC2_c32740 spo0A; stage 0 sporulation protein A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
C ERIC2_c19820 dctR; putative C4-dicarboxylate response regulator DctR K11692 K11692; two-component system, CitB family, response regulator DctR
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
C ERIC2_c01780 lytS; sensor protein LytS K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
C ERIC2_c01770 lytT; sensory transduction protein LytT K07705 lytT; two-component system, LytTR family, response regulator LytT
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C ERIC2_c21460 cheA; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C ERIC2_c21560 cheY; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C ERIC2_c21470 cheB; chemotaxis response regulator protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
C ERIC2_c30550 HAMP domain protein K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C ERIC2_c30540 Two component transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN
C ERIC2_c17610 response regulator receiver domain protein K07720 yesN; two-component system, response regulator YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C ERIC2_c14270 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
C ERIC2_c10950 putative sensor histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
C ERIC2_c10940 response regulator-like protein K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023