+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Petromyzon marinus (sea lamprey)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 116952073 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 116953434 RNGTT; mRNA-capping enzyme K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 116950603 CDK7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 116939571 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 116945754 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 isoform X1 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 116955016 RAMAC; RNA guanine-N7 methyltransferase activating subunit K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 116942177 NCBP1; nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 116945855 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 116955776 cleavage and polyadenylation specificity factor subunit 6-like isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 116950102 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 isoform X1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 116955779 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 116954086 CPSF1; cleavage and polyadenylation specificity factor subunit 1 isoform X1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 116943243 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 116945104 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 116958099 CPSF4; cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 116942784 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 116946985 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 116949453 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 116939175 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 116939394 serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 116948470 serine/threonine-protein phosphatase PP1-beta catalytic subunit-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 116943378 serine/threonine-protein phosphatase PP1-beta catalytic subunit-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 116946987 RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like isoform X1 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 116950393 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 116957807 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 116956587 cleavage stimulation factor subunit 2-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 116944426 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 116953972 SYMPK; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 116956139 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 116939207 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 116952111 SNRPE; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 116947567 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 116940605 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 116953377 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 116940631 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 116943243 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 116945104 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 116956587 cleavage stimulation factor subunit 2-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 116953972 SYMPK; symplekin K06100 SYMPK; symplekin
E 116941399 SLBP; histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
D DRB sensitivity inducing factor (DSIF) complex
E 116950289 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 116943146 SUPT5H; transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 116945844 METTL3; N6-adenosine-methyltransferase catalytic subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 116937948 METTL14; N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 116951896 METTL4; N(6)-adenine-specific DNA methyltransferase METTL4 isoform X1 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 116950137 METTL16; RNA N6-adenosine-methyltransferase METTL16 isoform X1 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 116955635 pre-mRNA-splicing regulator WTAP-like K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 116944262 VIRMA; protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 116942410 RNA-binding protein 15-like K13190 RBM15; RNA-binding protein 15
E 116952685 E3 ubiquitin-protein ligase Hakai-like isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 116939711 PAPOLG; poly(A) polymerase gamma isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 116948266 poly(A) polymerase beta-like isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 116950695 TENT2; poly(A) RNA polymerase GLD2 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 116941000 speckle targeted PIP5K1A-regulated poly(A) polymerase-like K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 116948736 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 116946051 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 116946908 TAR DNA-binding protein 43-like isoform X1 K23600 TARDBP; TAR DNA-binding protein 43
E 116949611 TAR DNA-binding protein 43-like isoform X1 K23600 TARDBP; TAR DNA-binding protein 43
E 116950410 LOW QUALITY PROTEIN: TAR DNA-binding protein 43-like K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 116947552 KIN; DNA/RNA-binding protein KIN17 isoform X1 K13102 KIN; DNA/RNA-binding protein KIN17
D 116956962 METTL22; methyltransferase-like protein 22 isoform X1 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 116953435 terminal nucleotidyltransferase 5C-like K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 116938300 terminal nucleotidyltransferase 5C-like K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 116946901 SRRT; serrate RNA effector molecule homolog isoform X1 K27103 SRRT; serrate RNA effector molecule
D 116950451 serrate RNA effector molecule homolog isoform X1 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 116939093 RBM8A; RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 116943518 protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 116949667 ALYREF; THO complex subunit 4 isoform X1 K12881 THOC4; THO complex subunit 4
E 116955415 spliceosome RNA helicase Ddx39b K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 116953999 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 116952704 CCDC174; coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 116954760 CASC3; protein CASC3 isoform X1 K14323 CASC3; protein CASC3
E 116952987 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 116958180 histone deacetylase complex subunit SAP18-like K14324 SAP18; histone deacetylase complex subunit SAP18
E 116947218 PNN; pinin K13114 PNN; pinin
D TREX complex
E 116951603 THOC1; THO complex subunit 1 isoform X1 K12878 THOC1; THO complex subunit 1
E 116943559 THOC2; THO complex subunit 2 isoform X1 K12879 THOC2; THO complex subunit 2
E 116940746 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 116949667 ALYREF; THO complex subunit 4 isoform X1 K12881 THOC4; THO complex subunit 4
E 116950291 THOC5; THO complex subunit 5 homolog isoform X1 K13174 THOC5; THO complex subunit 5
E 116957777 THOC6; THO complex subunit 6 homolog K13175 THOC6; THO complex subunit 6
E 116942299 THOC7; THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 116952489 PCID2; PCI domain-containing protein 2 isoform X1 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 116955706 SEM1; LOW QUALITY PROTEIN: 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 116954133 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 116953493 CETN3; centrin-3 K16466 CETN3; centrin-3
D Nuclear pore complex
E 116942610 RAE1; mRNA export factor K14298 RAE1; mRNA export factor
E 116947460 protein SEC13 homolog isoform X1 K14004 SEC13; protein transport protein SEC13
E 116949326 SEC13; protein SEC13 homolog isoform X1 K14004 SEC13; protein transport protein SEC13
E 116940075 NUP37; nucleoporin Nup37 isoform X1 K14302 NUP37; nuclear pore complex protein Nup37
E 116955166 NUP85; nuclear pore complex protein Nup85 isoform X1 K14304 NUP85; nuclear pore complex protein Nup85
E 116958689 NUP43; nucleoporin Nup43 isoform X1 K14305 NUP43; nuclear pore complex protein Nup43
E 116940018 NUP50; nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 116943654 nuclear pore complex protein Nup54-like K14308 NUP54; nuclear pore complex protein Nup54
E 116937121 nuclear pore complex protein Nup54-like K14308 NUP54; nuclear pore complex protein Nup54
E 116953867 NUP62; nuclear pore glycoprotein p62 K14306 NUP62; nuclear pore complex protein Nup62
E 116954053 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 116946026 NUP93; nuclear pore complex protein Nup93 isoform X1 K14309 NUP93; nuclear pore complex protein Nup93
E 116943025 nuclear pore complex protein Nup98-Nup96-like K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 116943604 LOW QUALITY PROTEIN: nuclear pore complex protein Nup98-Nup96-like K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 116940559 NUP107; nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 116947786 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 116955351 NUP188; nucleoporin NUP188 homolog K14311 NUP188; nuclear pore complex protein Nup188
E 116942672 nuclear pore complex protein Nup153-like isoform X1 K14296 NUP153; nuclear pore complex protein Nup153
E 116943319 NUP155; nuclear pore complex protein Nup155 isoform X1 K14312 NUP155; nuclear pore complex protein Nup155
E 116944542 NUP160; nuclear pore complex protein Nup160 isoform X1 K14303 NUP160; nuclear pore complex protein Nup160
E 116948423 NUP35; nucleoporin NUP35 isoform X1 K14313 NUP35; nuclear pore complex protein Nup53
E 116940014 NUP205; nuclear pore complex protein Nup205 isoform X1 K14310 NUP205; nuclear pore complex protein Nup205
E 116947560 NUP210; nuclear pore membrane glycoprotein 210 isoform X1 K14314 NUP210; nuclear pore complex protein Nup210
E 116953275 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 116955791 NUP58; nucleoporin p58/p45 isoform X1 K14307 NUPL1; nucleoporin p58/p45
E 116947158 NUP42; nucleoporin NUP42 K14321 NUPL2; nucleoporin-like protein 2
E 116951960 NDC1; nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 116954043 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 116952562 RANBP2; E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 116944006 AAAS; aladin isoform X1 K14320 AAAS; aladin
E 116953493 CETN3; centrin-3 K16466 CETN3; centrin-3
E 116953116 GLE1; nucleoporin GLE1 isoform X1 K18723 GLE1; nucleoporin GLE1
E 116949273 nucleoporin GLE1-like K18723 GLE1; nucleoporin GLE1
E 116947809 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 116955651 NXT2; NTF2-related export protein 2 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 116950081 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 116939853 acidic leucine-rich nuclear phosphoprotein 32 family member B-like isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 116950592 acidic leucine-rich nuclear phosphoprotein 32 family member A-like K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 116948948 ELAV-like protein 2 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 116937852 protein doublesex-like K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 116937998 ELAV-like protein 1 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 116951932 ELAV-like protein 2 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 116942284 transitional endoplasmic reticulum ATPase-like K13525 VCP; transitional endoplasmic reticulum ATPase
E 116951885 transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 116943163 VCPKMT; protein-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 116939562 XPO1; exportin-1 K14290 XPO1; exportin-1
E 116953920 exportin-1-like isoform X1 K14290 XPO1; exportin-1
E 116940548 XPO7; exportin-7 isoform X1 K18460 XPO7; exportin-7
E 116951459 RANGAP1; ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
D eIF4F and regulatory proteins
E 116940357 eukaryotic translation initiation factor 4E-like isoform X1 K03259 EIF4E; translation initiation factor 4E
E 116956321 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 116950872 eukaryotic translation initiation factor 4E-like K03259 EIF4E; translation initiation factor 4E
E 116957175 eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 116946822 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 116944633 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 116940860 eukaryotic translation initiation factor 4B-like isoform X1 K03258 EIF4B; translation initiation factor 4B
E 116938585 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 116939172 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 116951091 eukaryotic translation initiation factor 4E-binding protein 2-like K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 116947387 protein angel homolog 2-like K18729 ANGEL; protein angel
E 116956327 fragile X mental retardation syndrome-related protein 1-like isoform X1 K15516 FMR; fragile X mental retardation protein
E 116952511 fragile X mental retardation syndrome-related protein 1-like isoform X1 K15516 FMR; fragile X mental retardation protein
E 116953336 cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 116955768 cytoplasmic FMR1-interacting protein 2-like K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 116953276 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 116940488 transforming acidic coiled-coil-containing protein 3-like isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 116953623 cytoplasmic polyadenylation element-binding protein 1-like isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116941242 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116941280 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116944423 putative ATP-dependent RNA helicase Pl10 isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 116947049 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 116939778 polyadenylate-binding protein 1A-like K13126 PABPC; polyadenylate-binding protein
E 103091841 PABPC1; polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 116945202 polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 116953187 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 116940054 deformed epidermal autoregulatory factor 1 homolog isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 116942841 MCTS1; malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 116939201 DENR; density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 116956933 LOW QUALITY PROTEIN: APOBEC1 complementation factor-like K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 116954738 PYM1; partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 116940940 heterogeneous nuclear ribonucleoprotein A3-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116938498 heterogeneous nuclear ribonucleoprotein A3 homolog 1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116944693 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116948672 heterogeneous nuclear ribonucleoprotein A2 homolog 1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116953524 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 116958452 RNA-binding protein Musashi homolog 2-like isoform X1 K14411 MSI; RNA-binding protein Musashi
E 116950974 HBS1L; HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 116958421 PELO; protein pelota homolog K06965 PELO; protein pelota
E 116952021 PABPN1; polyadenylate-binding protein 2 isoform X1 K14396 PABPN1; polyadenylate-binding protein 2
E 116938054 ATP-dependent RNA helicase DDX19A-like K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 116944918 XAB2; pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 116943941 SARNP; SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 116946648 regulator of chromosome condensation-like isoform X1 K11493 RCC1; regulator of chromosome condensation
E 116945273 regulator of chromosome condensation-like K11493 RCC1; regulator of chromosome condensation
E 116940327 transcriptional activator protein Pur-alpha-like K21772 PURA; transcriptional activator protein Pur-alpha
E 116945001 transcriptional activator protein Pur-alpha-like K21772 PURA; transcriptional activator protein Pur-alpha
E 116953977 POLDIP3; polymerase delta-interacting protein 3 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 116956891 LENG8; leukocyte receptor cluster member 8 isoform X1 K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E 116940533 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 116955090 eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like K03267 ERF3; peptide chain release factor subunit 3
E 116941882 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 116947573 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 116956754 regulator of nonsense transcripts 3A-like K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 116956907 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1 K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 116950968 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform-like K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 116948148 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 116941205 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 116948269 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 116944599 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha-like isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 116952530 uncharacterized protein LOC116952530 isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 116939403 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 116947244 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform-like K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 116947830 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform-like isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 116948376 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 116957018 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform-like K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 116943370 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 116946174 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 116939998 SMG5; protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 116950153 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 116958192 SMG7; protein SMG7 K14409 SMG7; protein SMG7
E 116950099 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 116956761 SMG9; protein SMG9 K18735 SMG9; protein SMG9
E 116947049 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 116958559 selenocysteine insertion sequence-binding protein 2-like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 116949449 DHX34; probable ATP-dependent RNA helicase DHX34 isoform X1 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 116956686 GTPBP1; GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 116942206 unconventional myosin-Va-like isoform X1 K10357 MYO5; myosin V
E 116947403 BICD1; protein bicaudal D homolog 1 K18739 BICD; protein bicaudal D
E 116949356 protein bicaudal D homolog 2-like isoform X1 K18739 BICD; protein bicaudal D
E 116951185 protein bicaudal D homolog 2-like isoform X1 K18739 BICD; protein bicaudal D
E 116943586 EXD1; piRNA biogenesis protein EXD1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 116946217 actin, cytoplasmic 2-like K05692 ACTB_G1; actin beta/gamma 1
E 116951639 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 116952989 glial fibrillary acidic protein-like K07606 VIM; vimentin
E 116940419 vimentin-like K07606 VIM; vimentin
E 116941127 vimentin-like K07606 VIM; vimentin
E 116950106 T-box transcription factor TBX5-like K10180 TBX6; T-box protein 6
E 116940621 NANOS1; nanos homolog 1 isoform X1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 116958189 far upstream element-binding protein 1-like isoform X1 K13210 FUBP; far upstream element-binding protein
E 116938997 far upstream element-binding protein 1-like isoform X1 K13210 FUBP; far upstream element-binding protein
E 116946621 elongation factor 1-alpha, somatic form K03231 EEF1A; elongation factor 1-alpha
E 116937796 elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 116945224 elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 103091835 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 116940311 HAX1; HCLS1-associated protein X-1 K16220 HAX1; HCLS1-associated protein X-1
E 116956255 arf-GAP domain and FG repeat-containing protein 1-like isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 116956712 arf-GAP domain and FG repeat-containing protein 1-like K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 116952502 arf-GAP domain and FG repeat-containing protein 1-like K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 116942673 double-stranded RNA-binding protein Staufen homolog 2-like isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 116944002 insulin-like growth factor 2 mRNA-binding protein 3 isoform X1 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 116938203 LOW QUALITY PROTEIN: polypyrimidine tract-binding protein 1-like K13218 PTBP1; polypyrimidine tract-binding protein 1
E 116953623 cytoplasmic polyadenylation element-binding protein 1-like isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116941242 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116941280 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 116956327 fragile X mental retardation syndrome-related protein 1-like isoform X1 K15516 FMR; fragile X mental retardation protein
E 116952511 fragile X mental retardation syndrome-related protein 1-like isoform X1 K15516 FMR; fragile X mental retardation protein
E 116953336 cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 116955768 cytoplasmic FMR1-interacting protein 2-like K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 116940775 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 116948558 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 116948723 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 116938552 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 116945580 caprin-1-like isoform X1 K18743 CAPRIN1; caprin-1
E 116939970 caprin-2-like isoform X1 K18744 CAPRIN2; caprin-2
E 116950390 YBX1; Y-box-binding protein 1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 116945882 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 116946559 protein argonaute-1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 116946611 protein argonaute-2-like isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 116945233 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 116940357 eukaryotic translation initiation factor 4E-like isoform X1 K03259 EIF4E; translation initiation factor 4E
E 116956321 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 116950872 eukaryotic translation initiation factor 4E-like K03259 EIF4E; translation initiation factor 4E
E 116941882 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 116944423 putative ATP-dependent RNA helicase Pl10 isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 116948195 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 116939299 RNA-binding protein MEX3B-like K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 116941890 RNA-binding protein MEX3B-like K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 116950721 LOW QUALITY PROTEIN: RNA-binding protein MEX3A-like K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 116946338 FASTK; fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 116945968 protein LSM14 homolog B-like isoform X1 K18749 LSM14; protein LSM14
E 116954216 protein LSM14 homolog B-like isoform X1 K18749 LSM14; protein LSM14
E 116950390 YBX1; Y-box-binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 116954178 Wilms tumor protein 1-interacting protein homolog K16682 AJUBA; LIM domain-containing protein
E 116955986 thyroid receptor-interacting protein 6-like K16682 AJUBA; LIM domain-containing protein
E 116944271 LIMD1; LIM domain-containing protein 1 isoform X1 K16682 AJUBA; LIM domain-containing protein
E 116957308 single-stranded DNA cytosine deaminase-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 116952208 MOV10; helicase MOV-10 isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 116946174 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 116939998 SMG5; protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 116950153 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 116958192 SMG7; protein SMG7 K14409 SMG7; protein SMG7
E 116939448 mRNA decay activator protein ZFP36L1-like K18753 ZFP36L; butyrate response factor
E 116947297 mRNA decay activator protein ZFP36L2-A-like K18753 ZFP36L; butyrate response factor
E 116947728 mRNA decay activator protein ZFP36L1-like K18753 ZFP36L; butyrate response factor
E 116953043 protein lin-28 homolog B-like isoform X1 K18754 LIN28; protein lin-28
E 116940405 HTT; huntingtin isoform X1 K04533 HD; huntingtin
E 116940198 BICC1; protein bicaudal C homolog 1 isoform X1 K18756 BICC1; protein bicaudal C
E 116940940 heterogeneous nuclear ribonucleoprotein A3-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116938498 heterogeneous nuclear ribonucleoprotein A3 homolog 1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116944693 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116948672 heterogeneous nuclear ribonucleoprotein A2 homolog 1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 116944602 cAMP-dependent protein kinase catalytic subunit alpha-like isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 116951840 cAMP-dependent protein kinase catalytic subunit alpha isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 116955653 la-related protein 1-like K18757 LARP1; la-related protein 1
E 116942898 LARP1B; la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 116950060 ataxin-2-like isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 116957636 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 116949354 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 116940733 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 116955365 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 116951278 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 116940902 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 116947586 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 116953662 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 116941004 U6 snRNA-associated Sm-like protein LSm7 isoform X1 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 116952264 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 116939785 kinesin light chain 1-like isoform X1 K10407 KLC; kinesin light chain
E 116947205 LOW QUALITY PROTEIN: kinesin light chain 1-like K10407 KLC; kinesin light chain
E 116953992 kinesin light chain 1-like isoform X1 K10407 KLC; kinesin light chain
E 116943222 KLC1; kinesin light chain 1 K10407 KLC; kinesin light chain
E 116942206 unconventional myosin-Va-like isoform X1 K10357 MYO5; myosin V
E 116947505 tubulin alpha chain, testis-specific-like K07374 TUBA; tubulin alpha
E 116947506 tubulin alpha-1A chain-like K07374 TUBA; tubulin alpha
E 116947507 tubulin alpha chain, testis-specific-like K07374 TUBA; tubulin alpha
E 116954703 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 116943764 tubulin alpha-1A chain-like K07374 TUBA; tubulin alpha
E 116937310 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 116938693 tubulin alpha-1A chain-like K07374 TUBA; tubulin alpha
E 116945539 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 116953623 cytoplasmic polyadenylation element-binding protein 1-like isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116941242 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116941280 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 116953276 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 116940488 transforming acidic coiled-coil-containing protein 3-like isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 116946186 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 116949497 trinucleotide repeat-containing gene 6A protein-like K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 116955066 trinucleotide repeat-containing gene 6C protein-like isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 116946018 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 116944376 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 116949522 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 116945663 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 116950956 CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 116942791 DIS3L2; DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 116948564 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 116943572 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 116947619 protein BTG1-like K14443 TOB; protein Tob/BTG
E 116956909 protein BTG4-like K14443 TOB; protein Tob/BTG
E 116951516 protein Tob1-like K14443 TOB; protein Tob/BTG
E 116952350 protein BTG1-like isoform X1 K14443 TOB; protein Tob/BTG
E 116958459 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 116955043 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 116945726 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 116947573 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 116956754 regulator of nonsense transcripts 3A-like K14328 UPF3; regulator of nonsense transcripts 3
E 116956033 E3 ubiquitin-protein ligase TRIM71-like isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 116944281 E3 ubiquitin-protein ligase TRIM71-like K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 116944871 RING finger protein nhl-1-like isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 116939768 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 116955962 ZAR1L; ZAR1-like protein isoform X1 K18762 ZAR1; zygote arrest protein 1
E 116941736 YTH domain-containing family protein 3-like K20102 YTHDF; YTH domain-containing family protein
E 116942559 LOW QUALITY PROTEIN: YTH domain-containing family protein 3-like K20102 YTHDF; YTH domain-containing family protein
E 116951284 YTH domain-containing family protein 3-like K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 116941202 nucleolysin TIA-1-like isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 116939778 polyadenylate-binding protein 1A-like K13126 PABPC; polyadenylate-binding protein
E 103091841 PABPC1; polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 116945202 polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 116942673 double-stranded RNA-binding protein Staufen homolog 2-like isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 116956327 fragile X mental retardation syndrome-related protein 1-like isoform X1 K15516 FMR; fragile X mental retardation protein
E 116952511 fragile X mental retardation syndrome-related protein 1-like isoform X1 K15516 FMR; fragile X mental retardation protein
E 116937608 ras GTPase-activating protein-binding protein 1-like isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 116940369 G3BP2; ras GTPase-activating protein-binding protein 2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 116952459 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 116951498 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 116957175 eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 116953999 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 116940860 eukaryotic translation initiation factor 4B-like isoform X1 K03258 EIF4B; translation initiation factor 4B
E 116938585 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 116946822 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 116944633 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 116953403 ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 116956558 ribosomal protein S6 kinase alpha-3-like isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 103091703 RACK1; receptor of activated protein C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 116957399 TNF receptor-associated factor 2-like isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 116957458 TNF receptor-associated factor 2-like isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 116947809 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 116949292 HDAC6; histone deacetylase 6 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 116948683 la-related protein 4-like isoform X1 K18763 LARP4; la-related protein 4
E 116949268 la-related protein 4-like isoform X1 K18763 LARP4; la-related protein 4
E 116938816 la-related protein 4-like isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 116949354 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 116957636 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 116948195 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 116955043 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 116945726 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 116958459 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 116940733 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 116955365 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 116951278 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 116940902 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 116947586 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 116953662 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 116941004 U6 snRNA-associated Sm-like protein LSm7 isoform X1 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 116952264 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 116945882 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 116953841 XRN2; 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 116957441 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 116955178 HELZ; probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 116941402 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 116953122 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 116946124 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 116944202 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 116953837 EXOSC5; exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 116956352 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 116944274 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 116942848 EXOSC8; exosome complex component RRP43 isoform X1 K12586 RRP43; exosome complex component RRP43
E 116942947 EXOSC9; exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 116938182 exosome complex exonuclease RRP44-like K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 116938439 exosome complex exonuclease RRP44-like K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 116940782 DIS3L; DIS3-like exonuclease 1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 116939016 exosome component 10-like isoform X1 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 116939031 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 116942156 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 116957012 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E 116944105 TENT4A; terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 116940220 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 116941950 MTREX; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
E 116948772 exosome RNA helicase MTR4-like K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 116953187 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 116950640 TTC37; tetratricopeptide repeat protein 37 isoform X1 K12600 SKI3; superkiller protein 3
E 116942032 WDR61; WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 116950956 CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 116946018 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 116944376 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 116949522 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 116945663 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 116938628 CNOT9; CCR4-NOT transcription complex subunit 9 isoform X1 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 116944287 CNOT10; CCR4-NOT transcription complex subunit 10 isoform X1 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 116948564 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 116943572 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 116953221 poly(A)-specific ribonuclease PARN-like K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 116943358 poly(A)-specific ribonuclease PNLDC1-like K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 116946861 DHX36; ATP-dependent DNA/RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 116947619 protein BTG1-like K14443 TOB; protein Tob/BTG
E 116956909 protein BTG4-like K14443 TOB; protein Tob/BTG
E 116951516 protein Tob1-like K14443 TOB; protein Tob/BTG
E 116952350 protein BTG1-like isoform X1 K14443 TOB; protein Tob/BTG
E 116944946 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 116940662 ERI1; 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 116957441 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 116952326 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 116955178 HELZ; probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 116940257 HELZ2; helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 116947845 NRDE2; nuclear exosome regulator NRDE2 isoform X1 K26109 NRDE2; nuclear exosome regulator NRDE2
E 116942167 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 116955576 endoribonuclease ZC3H12A-like K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 116937434 endoribonuclease ZC3H12A-like K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
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AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 116957850 DROSHA; ribonuclease 3 isoform X1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 116948070 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 116946993 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 116951700 alpha-enolase-like K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 116939020 alpha-enolase-like K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 116947840 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 116941058 ATP-dependent 6-phosphofructokinase, muscle type-like K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 116948704 ATP-dependent 6-phosphofructokinase, platelet type-like K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 116938804 ATP-dependent 6-phosphofructokinase, platelet type-like isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 116945286 ATP-dependent 6-phosphofructokinase, platelet type-like K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 116940560 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 116943987 HSPD1; LOW QUALITY PROTEIN: 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E 116943988 60 kDa heat shock protein, mitochondrial-like K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 116953122 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 116941402 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 116944202 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 116944274 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024