+F Chromosome and associated proteins KO
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Chromosome and Associated Proteins - Pieris napi (green-veined white)
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AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
D 125048685 structural maintenance of chromosomes protein 1A K06636 SMC1; structural maintenance of chromosome 1
D 125058686 structural maintenance of chromosomes protein 3 K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
D 125049379 double-strand-break repair protein rad21 homolog isoform X1 K06670 SCC1; cohesin complex subunit SCC1
D 125048571 cohesin subunit SA-1 isoform X1 K06671 STAG1_2; cohesin complex subunit SA-1/2
C Adherin complex
D 125053144 nipped-B-like protein K06672 SCC2; cohesin loading factor subunit SCC2
D 125052211 MAU2 chromatid cohesion factor homolog K11266 MAU2; MAternally affected uncoordination
D 125059935 sister chromatid cohesion protein PDS5 homolog B isoform X1 K11267 PDS5; sister chromatid cohesion protein PDS5
C CTF18-RFC complex
D 125049970 chromosome transmission fidelity protein 8 homolog K11270 CTF8; chromosome transmission fidelity protein 8
D 125050563 sister chromatid cohesion protein DCC1 isoform X1 K11271 DSCC1; sister chromatid cohesion protein DCC1
D 125056486 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 125061796 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 125052480 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 125049089 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C Fork protection complex
D 125063636 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 125052913 TIMELESS-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Other sister chromatid cohesion factors
D 125053411 ATP-dependent DNA helicase DDX11 K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
D 125050267 WD repeat and HMG-box DNA-binding protein 1 K11274 WDHD1; chromosome transmission fidelity protein 4
D 125056385 N-alpha-acetyltransferase 11 K20791 NAA10_11; N-alpha-acetyltransferase 10/11 [EC:2.3.1.255]
D 125056677 N-alpha-acetyltransferase 15, NatA auxiliary subunit K20792 NAA15_16; N-alpha-acetyltransferase 15/16, NatA auxiliary subunit
D 125057085 probable N-acetyltransferase san K20793 NAA50; N-alpha-acetyltransferase 50 [EC:2.3.1.258 2.3.1.309]
B Meiosis-specific proteins
C Cohesin complex and associated proteins
D 125048685 structural maintenance of chromosomes protein 1A K06636 SMC1; structural maintenance of chromosome 1
D 125058686 structural maintenance of chromosomes protein 3 K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
D 125049480 protein wings apart-like K25163 WAPL; wings apart-like protein
C Synaptonemal complex
C DSB formation-related proteins
D 125053194 meiotic recombination protein SPO11 K10878 SPO11; meiotic recombination protein SPO11
C Others
D 125057393 meiotic recombination protein DMC1/LIM15 homolog K10872 DMC1; meiotic recombination protein DMC1
D 125052451 zip homologous protein 2 isoform X1 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
B Nucleosome assembly factors
C Histones
D 125061857 histone H2A K11251 H2A; histone H2A
D 125049936 histone H2A.V K11251 H2A; histone H2A
D 125061858 histone H2B K11252 H2B; histone H2B
D 125057887 histone H3.3A K11253 H3; histone H3
D 125061856 histone H3 K11253 H3; histone H3
D 125061859 histone H4 K11254 H4; histone H4
D 125062976 histone H4 K11254 H4; histone H4
D 125062977 histone H4 K11254 H4; histone H4
C Histone chaperones
D Nucleoplasmins
E 125054310 nucleoplasmin-like protein isoform X1 K11278 NPM3; nucleophosmin 3
D NAPs (Nucleosome assembly proteins)
E 125056386 nucleosome assembly protein 1-like 1 isoform X1 K11282 NAP1L4; nucleosome assembly protein 1-like 4
D CAF-1
E 125055099 chromatin assembly factor 1 subunit B K10751 CHAF1B; chromatin assembly factor 1 subunit B
E 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D FACT complex
E 125048986 FACT complex subunit Ssrp1 K09272 SSRP1; FACT complex subunit SSRP1/POB3
E 125049501 FACT complex subunit spt16 K25639 SUPT16H; FACT complex subunit SPT16
D Other Histone chaperones and regulators
E 125061121 histone chaperone asf1 K10753 ASF1; histone chaperone ASF1
E 125054974 codanin-1 isoform X1 K19531 CDAN1; codanin-1
E 125052926 CDAN1-interacting nuclease 1 isoform X1 K24865 CDIN1; CDAN1-interacting nuclease 1
E 125049328 protein HGV2 isoform X1 K11291 NASP; nuclear autoantigenic sperm protein
E 125048706 transcription elongation factor SPT6 K11292 SUPT6H; transcription elongation factor SPT6
E 125054709 protein HIRA homolog isoform X1 K11293 HIRA; protein HIRA/HIR1
C HMG (high mobility group) proteins
D 125056001 high mobility group protein HMGI-C K09283 HMGA2; high mobility group AT-hook protein 2
D 125058035 high mobility group protein DSP1-like isoform X1 K10802 HMGB1; high mobility group protein B1
D 125055081 HMG box-containing protein 4 K11298 HMGXB4; HMG domain-containing protein 4
B Histone modification proteins
C HATs (histone acetyltransferases)
D 125053806 histone acetyltransferase type B catalytic subunit K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
D 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
D 125059016 CREB-binding protein isoform X1 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D 125049948 transcription initiation factor TFIID subunit 1 K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
D 125057383 histone acetyltransferase Tip60 isoform X1 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D 125049587 histone acetyltransferase KAT8 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D 125051080 histone acetyltransferase KAT7 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
D 125062764 histone acetyltransferase KAT7-like isoform X1 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
D 125062666 circadian locomoter output cycles protein kaput isoform X1 K02223 CLOCK; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
D 125052408 N-alpha-acetyltransferase 40 K20794 NAA40; N-alpha-acetyltransferase 40 [EC:2.3.1.257]
D 125057176 N-alpha-acetyltransferase 60 K21121 NAA60; N-alpha-acetyltransferase 60 [EC:2.3.1.259]
C HAT complexes
D PCAF complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 125062394 transcription initiation protein SPT3 homolog K11313 SUPT3H; transcription initiation protein SPT3
E 125059694 transcriptional adapter 2A K11314 TADA2A; transcriptional adapter 2-alpha
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
E 125056549 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125049755 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125061891 transcription initiation factor TFIID subunit 6-like isoform X1 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 125060612 transcription initiation factor TFIID subunit 9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E 125058477 transcription initiation factor TFIID subunit 10-like K03134 TAF10; transcription initiation factor TFIID subunit 10
E 125051961 transcription initiation factor TFIID subunit 12 K03126 TAF12; transcription initiation factor TFIID subunit 12
D STAGA complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 125062394 transcription initiation protein SPT3 homolog K11313 SUPT3H; transcription initiation protein SPT3
E 125062256 uncharacterized protein LOC125062256 K11316 SUPT7L; STAGA complex 65 subunit gamma
E 125059351 transcriptional adapter 1-like K11317 TADA1; transcriptional adapter 1
E 125053069 transcriptional adapter 2B isoform X1 K15127 TADA2B; transcriptional adapter 2-beta
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
E 125056549 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125049755 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125061891 transcription initiation factor TFIID subunit 6-like isoform X1 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 125060612 transcription initiation factor TFIID subunit 9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E 125058477 transcription initiation factor TFIID subunit 10-like K03134 TAF10; transcription initiation factor TFIID subunit 10
E 125051961 transcription initiation factor TFIID subunit 12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E 125048642 splicing factor 3B subunit 3 isoform X1 K12830 SF3B3; splicing factor 3B subunit 3
D TFTC complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 125062394 transcription initiation protein SPT3 homolog K11313 SUPT3H; transcription initiation protein SPT3
E 125053069 transcriptional adapter 2B isoform X1 K15127 TADA2B; transcriptional adapter 2-beta
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
E 125061372 ataxin-7-like K11318 ATXN7; ataxin-7
E 125049488 transcription initiation factor TFIID subunit 2 K03128 TAF2; transcription initiation factor TFIID subunit 2
E 125056549 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125049755 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125061891 transcription initiation factor TFIID subunit 6-like isoform X1 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 125055438 transcription initiation factor TFIID subunit 7 K03132 TAF7; transcription initiation factor TFIID subunit 7
E 125060612 transcription initiation factor TFIID subunit 9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E 125058477 transcription initiation factor TFIID subunit 10-like K03134 TAF10; transcription initiation factor TFIID subunit 10
E 125051961 transcription initiation factor TFIID subunit 12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E 125048642 splicing factor 3B subunit 3 isoform X1 K12830 SF3B3; splicing factor 3B subunit 3
D TIP60 complex
E 125057383 histone acetyltransferase Tip60 isoform X1 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 125060927 inhibitor of growth protein 3 K11319 ING3; inhibitor of growth protein 3
E 125061365 bromodomain-containing protein 8-like isoform X1 K11321 BRD8; bromodomain-containing protein 8
E 125062301 uncharacterized protein LOC125062301 isoform X1 K11322 EPC; enhancer of polycomb-like protein
E 125052420 DNA methyltransferase 1-associated protein 1 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
E 125056033 ruvB-like helicase 1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
E 125061102 ruvB-like 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
E 125050565 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 125057293 actin-5C K05692 ACTB_G1; actin beta/gamma 1
E 125057294 actin, cytoplasmic A3a K05692 ACTB_G1; actin beta/gamma 1
E 125054835 YEATS domain-containing protein 4 K11341 YEATS4; YEATS domain-containing protein 4
E 125050202 MRG/MORF4L-binding protein K11343 MRGBP; MRG-binding protein
E 125050795 chromatin modification-related protein MEAF6 K11344 MEAF6; chromatin modification-related protein EAF6
D HBO1 complex
E 125051080 histone acetyltransferase KAT7 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
E 125062764 histone acetyltransferase KAT7-like isoform X1 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
E 125060905 inhibitor of growth protein 5 K11345 ING5; inhibitor of growth protein 5
E 125062207 PHD finger protein rhinoceros K22156 JADE3; protein Jade-3
E 125050795 chromatin modification-related protein MEAF6 K11344 MEAF6; chromatin modification-related protein EAF6
D MOZ/MORF complex
E 125060905 inhibitor of growth protein 5 K11345 ING5; inhibitor of growth protein 5
E 125053739 bromodomain-containing protein 1 isoform X1 K11348 BRPF1; bromodomain and PHD finger-containing protein 1
E 125050795 chromatin modification-related protein MEAF6 K11344 MEAF6; chromatin modification-related protein EAF6
D SAGA complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 125062394 transcription initiation protein SPT3 homolog K11313 SUPT3H; transcription initiation protein SPT3
E 125061160 transcription factor SPT20 homolog isoform X1 K21245 SUPT20H; transcription factor SPT20 homolog
E 125059694 transcriptional adapter 2A K11314 TADA2A; transcriptional adapter 2-alpha
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
E 125054701 SAGA-associated factor 11 homolog K11363 SGF11; SAGA-associated factor 11
E 125061919 SAGA-associated factor 29 K11364 SGF29; SAGA-associated factor 29
E 125056549 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125049755 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125061891 transcription initiation factor TFIID subunit 6-like isoform X1 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 125060612 transcription initiation factor TFIID subunit 9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E 125058477 transcription initiation factor TFIID subunit 10-like K03134 TAF10; transcription initiation factor TFIID subunit 10
E 125051961 transcription initiation factor TFIID subunit 12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E 125049474 ubiquitin carboxyl-terminal hydrolase nonstop K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E 125054009 chromodomain-helicase-DNA-binding protein 1 isoform X1 K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E 125056976 enhancer of yellow 2 transcription factor-like K11368 ENY2; enhancer of yellow 2 transcription factor
D SLIK complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 125062394 transcription initiation protein SPT3 homolog K11313 SUPT3H; transcription initiation protein SPT3
E 125059694 transcriptional adapter 2A K11314 TADA2A; transcriptional adapter 2-alpha
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
E 125054701 SAGA-associated factor 11 homolog K11363 SGF11; SAGA-associated factor 11
E 125061919 SAGA-associated factor 29 K11364 SGF29; SAGA-associated factor 29
E 125056549 transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125049755 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L K03130 TAF5; transcription initiation factor TFIID subunit 5
E 125061891 transcription initiation factor TFIID subunit 6-like isoform X1 K03131 TAF6; transcription initiation factor TFIID subunit 6
E 125060612 transcription initiation factor TFIID subunit 9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E 125058477 transcription initiation factor TFIID subunit 10-like K03134 TAF10; transcription initiation factor TFIID subunit 10
E 125051961 transcription initiation factor TFIID subunit 12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E 125049474 ubiquitin carboxyl-terminal hydrolase nonstop K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E 125054009 chromodomain-helicase-DNA-binding protein 1 isoform X1 K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
D ADA-HAT complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125059694 transcriptional adapter 2A K11314 TADA2A; transcriptional adapter 2-alpha
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
E 125061919 SAGA-associated factor 29 K11364 SGF29; SAGA-associated factor 29
D HAT-A2 complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125059694 transcriptional adapter 2A K11314 TADA2A; transcriptional adapter 2-alpha
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
D ATAC complex
E 125051800 histone acetyltransferase KAT2A isoform X1 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E 125059694 transcriptional adapter 2A K11314 TADA2A; transcriptional adapter 2-alpha
E 125060851 transcriptional adapter 3 K11315 TADA3; transcriptional adapter 3
E 125061919 SAGA-associated factor 29 K11364 SGF29; SAGA-associated factor 29
E 125055943 ZZ-type zinc finger-containing protein 3 K24536 ZZZ3; ZZ-type zinc finger-containing protein 3
E 125059692 cysteine-rich protein 2-binding protein K24537 KAT14; cysteine-rich protein 2-binding protein
E 125056982 protein Dr1 isoform X1 K21751 DR1; down-regulator of transcription 1
E 125055822 WD repeat-containing protein 5 K14963 WDR5; COMPASS component SWD3
D HATB complex
E 125053806 histone acetyltransferase type B catalytic subunit K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
E 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D NSL complex
E 125049587 histone acetyltransferase KAT8 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E 125055822 WD repeat-containing protein 5 K14963 WDR5; COMPASS component SWD3
E 125055917 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E 125062793 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit-like K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E 125055127 microspherule protein 1 K11674 MCRS1; microspherule protein 1
E 125056415 host cell factor 1-like K14966 HCFC1; host cell factor 1
D MSL complex
E 125049587 histone acetyltransferase KAT8 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E 125049178 E3 ubiquitin-protein ligase MSL2 K13164 MSL2; male-specific lethal 2
D NuA3 complex
D NuA4 complex
E 125057383 histone acetyltransferase Tip60 isoform X1 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
E 125054835 YEATS domain-containing protein 4 K11341 YEATS4; YEATS domain-containing protein 4
E 125052420 DNA methyltransferase 1-associated protein 1 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
E 125050565 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 125050795 chromatin modification-related protein MEAF6 K11344 MEAF6; chromatin modification-related protein EAF6
E 125062301 uncharacterized protein LOC125062301 isoform X1 K11322 EPC; enhancer of polycomb-like protein
E 125057293 actin-5C K05692 ACTB_G1; actin beta/gamma 1
E 125057294 actin, cytoplasmic A3a K05692 ACTB_G1; actin beta/gamma 1
D SAS complex
C HDACs (histone deacetylases)
D Class I HDACs
E 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E 125053994 histone deacetylase 3 K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
E 125054220 histone deacetylase 8-like isoform X1 K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
D Class II HDACs
E 125048925 histone deacetylase 7 isoform X1 K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
E 125059937 histone deacetylase 6 isoform X1 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D SIRTs (sirtuins, class III HDACs)
E 125049031 NAD-dependent protein deacetylase sirtuin-2-like isoform X1 K11412 SIRT2; NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
E 125053960 NAD-dependent protein deacylase Sirt4 K11414 SIRT4; NAD-dependent protein deacetylase/lipoamidase sirtuin 4 [EC:2.3.1.286 2.3.1.313]
E 125053329 NAD-dependent protein deacylase-like K11415 SIRT5; NAD-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
E 125050623 NAD-dependent protein deacetylase Sirt6 isoform X1 K11416 SIRT6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
E 125057816 NAD-dependent protein deacetylase sirtuin-7 K11417 SIRT7; NAD-dependent protein deacetylase sirtuin 7 [EC:2.3.1.286]
D Class IV HDACs
E 125051894 histone deacetylase 11 isoform X1 K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
C HDAC complexes
D Sin3A-HDAC complex
E 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
E 125054786 sin3 histone deacetylase corepressor complex component SDS3 K19201 SUDS3; Sin3 histone deacetylase corepressor complex component SDS3
E 125058038 histone deacetylase complex subunit SAP30 homolog K19202 SAP30; histone deacetylase complex subunit SAP30
E 125057008 histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 125051768 breast cancer metastasis-suppressor 1-like protein K19196 BRMS1; breast cancer metastasis-suppressor 1 and related proteins
E 125051584 inhibitor of growth protein 1 K19197 ING1; inhibitor of growth protein 1
D BRAF-HDAC complex
E 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E 125063026 lysine-specific histone demethylase 1A K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
E 125057682 uncharacterized protein LOC125057682 K24651 PHF21A; PHD finger protein 21A
E 125051600 zinc finger MYM-type protein 3 isoform X1 K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4
D REST complex
E 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E 125051754 REST corepressor 1 isoform X1 K26242 RCOR2_3; REST corepressor 2/3
E 125063026 lysine-specific histone demethylase 1A K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
E 125055757 ATP-dependent helicase brm K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D SHIP complex
E 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D MiDAC complex
E 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SMART complex
E 125053994 histone deacetylase 3 K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
E 125051092 MADS-box MEF2 type transcription factor MIG1 isoform X1 K15307 GPS2; G protein pathway suppressor 2
E 125061895 F-box-like/WD repeat-containing protein TBL1X K04508 TBL1; transducin (beta)-like 1
E 125062450 F-box-like/WD repeat-containing protein ebi isoform X1 K04508 TBL1; transducin (beta)-like 1
D Other HDAC associated proteins
E 125060628 DNA-binding protein RFXANK isoform X1 K21486 ANKRA2; ankyrin repeat family A protein 2
E 125050833 activating signal cointegrator 1 K23398 TRIP4; activating signal cointegrator 1
E 125053991 PHD finger protein 12 K26244 PHF12; transcriptional regulatory protein PHF12/RCO1
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
E 125050040 histone-lysine N-methyltransferase ash1 isoform X1 K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
E 125053543 histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
E 125048650 histone-lysine N-methyltransferase E(z) isoform X1 K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
E 125051581 histone-lysine N-methyltransferase trithorax K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
E 125063461 histone-lysine N-methyltransferase 2C-like isoform X1 K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
E 125060651 histone-lysine N-methyltransferase PRDM16-like isoform X1 K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
E 125060370 uncharacterized protein LOC125060370 K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
E 125053877 histone-lysine N-methyltransferase SETD1 isoform X1 K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E 125060208 SET domain-containing protein 4 K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
E 125054222 histone-lysine N-methyltransferase PR-Set7 K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
E 125054661 histone-lysine N-methyltransferase SETMAR-like K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
E 125062618 histone-lysine N-methyltransferase SETMAR-like K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
E 125063386 histone-lysine N-methyltransferase SMYD3 K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
E 125061082 histone-lysine N-methyltransferase Suv4-20 K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
D PRMTs (protein arginine metyltransferases)
E 125049739 protein arginine N-methyltransferase 1 K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
E 125056251 protein arginine N-methyltransferase 3 K11436 PRMT3; type I protein arginine methyltransferase [EC:2.1.1.319]
E 125050271 histone-arginine methyltransferase CARMER K05931 CARM1; type I protein arginine methyltransferase [EC:2.1.1.319]
E 125061938 probable protein arginine N-methyltransferase 6.1 K11437 PRMT6; type I protein arginine methyltransferase [EC:2.1.1.319]
E 125056257 protein arginine N-methyltransferase 5 K02516 PRMT5; type II protein arginine methyltransferase [EC:2.1.1.320]
E 125050929 protein arginine N-methyltransferase 9-like K19737 PRMT9; type II protein arginine methyltransferase [EC:2.1.1.320]
E 125057119 protein arginine N-methyltransferase 7 isoform X1 K11438 PRMT7; type III protein arginine methyltransferase [EC:2.1.1.321]
C HMT complexes
D COMPASS/SET1 complex
E 125053877 histone-lysine N-methyltransferase SETD1 isoform X1 K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E 125054636 CXXC-type zinc finger protein 1-like isoform X1 K14960 CXXC1; COMPASS component SPP1
E 125052564 retinoblastoma-binding protein 5 homolog K14961 RBBP5; COMPASS component SWD1
E 125056695 WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 125055822 WD repeat-containing protein 5 K14963 WDR5; COMPASS component SWD3
E 125052915 set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1 K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E 125056415 host cell factor 1-like K14966 HCFC1; host cell factor 1
D COMPASS/SET1 complex (yeast)
E 125053877 histone-lysine N-methyltransferase SETD1 isoform X1 K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E 125054636 CXXC-type zinc finger protein 1-like isoform X1 K14960 CXXC1; COMPASS component SPP1
E 125052564 retinoblastoma-binding protein 5 homolog K14961 RBBP5; COMPASS component SWD1
E 125056695 WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 125055822 WD repeat-containing protein 5 K14963 WDR5; COMPASS component SWD3
D MLL-HCF complex
E 125051581 histone-lysine N-methyltransferase trithorax K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
E 125052915 set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1 K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E 125052564 retinoblastoma-binding protein 5 homolog K14961 RBBP5; COMPASS component SWD1
E 125055822 WD repeat-containing protein 5 K14963 WDR5; COMPASS component SWD3
E 125056415 host cell factor 1-like K14966 HCFC1; host cell factor 1
E 125052604 menin isoform X1 K14970 MEN1; menin
D MLL3/MLL4 complex
E 125063461 histone-lysine N-methyltransferase 2C-like isoform X1 K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
E 125052915 set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1 K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E 125052564 retinoblastoma-binding protein 5 homolog K14961 RBBP5; COMPASS component SWD1
E 125055822 WD repeat-containing protein 5 K14963 WDR5; COMPASS component SWD3
E 125056397 PAX-interacting protein 1-like K14972 PAXIP1; PAX-interacting protein 1
E 125049773 lysine-specific demethylase 6A isoform X1 K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68]
D Dot1-containing complex
E 125053543 histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
C Histone demethylases
D 125063026 lysine-specific histone demethylase 1A K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
D 125053814 jmjC domain-containing histone demethylation protein 1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
D 125052488 lysine-specific demethylase 3A isoform X1 K15601 KDM3; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]
D 125058164 probable lysine-specific demethylase 4B K06709 KDM4; [histone H3]-trimethyl-L-lysine9/36 demethylase [EC:1.14.11.66 1.14.11.69]
D 125059045 lysine-specific demethylase lid-like K11446 KDM5; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]
D 125059716 lysine-specific demethylase lid-like K11446 KDM5; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]
D 125049773 lysine-specific demethylase 6A isoform X1 K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68]
D 125058447 bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 K16914 RIOX1; protein-L-histidine (3S)-3-hydroxylase / [histone H3]-trimethyl-L-lysine4/36 demethylase [EC:1.14.11.79 1.14.11.67 1.14.11.69]
D 125059657 bifunctional arginine demethylase and lysyl-hydroxylase PSR K11323 JMJD6; histone arginine demethylase JMJD6 [EC:1.14.11.-]
D 125059541 bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 isoform X1 K19219 JMJD7; peptidyl-lysine (3S)-dioxygenase / protease [EC:1.14.11.63 3.4.-.-]
D 125060502 DNA N6-methyl adenine demethylase isoform X1 K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
C Polycomb repressive complex (PRC) and associated proteins
D Canonical PRC1 (PRC1.2/1.4)
E 125051145 E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E 125053132 polycomb group protein Pc K11454 CBX7; chromobox protein 7
E PRC1.4 specific proteins
F 125063027 polycomb protein Scm isoform X1 K11461 SCMH1; polycomb protein SCMH1
F 125055366 polycomb protein Sfmbt isoform X1 K26269 SFMBT; scm-like with four MBT domains protein
D Noncanonical PRC1 (PRC1.1)
E 125051145 E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E 125053187 YY1-associated factor 2 K11468 YAF2; YY1-associated factor 2
E 125053814 jmjC domain-containing histone demethylation protein 1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 125061479 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Noncanonical PRC1 (PRC1.3/1.5)
E 125051145 E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E 125053548 polycomb group RING finger protein 3 K11488 PCGF3; polycomb group RING finger protein 3
E 125053187 YY1-associated factor 2 K11468 YAF2; YY1-associated factor 2
E 125063271 casein kinase II subunit beta-like K03115 CSNK2B; casein kinase II subunit beta
E 125063531 casein kinase II subunit beta isoform X1 K03115 CSNK2B; casein kinase II subunit beta
E 125050927 DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
D Noncanonical PRC1 (PRC1.6)
E 125051145 E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E 125053187 YY1-associated factor 2 K11468 YAF2; YY1-associated factor 2
E 125056417 transcription factor Dp-1 isoform X1 K04683 TFDP1; transcription factor Dp-1
E 125052968 protein max isoform X1 K04453 MAX; Max protein
E 125055822 WD repeat-containing protein 5 K14963 WDR5; COMPASS component SWD3
E 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D PRC2.1
E 125048650 histone-lysine N-methyltransferase E(z) isoform X1 K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
E 125057972 polycomb protein EED K11462 EED; polycomb protein EED
E 125057344 polycomb protein suz12-B K11463 SUZ12; polycomb protein SUZ12
E 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
E 125056027 polycomb protein Pcl isoform X1 K11485 MTF2; metal regulatory transcription factor 2
D PRC2.2
E 125048650 histone-lysine N-methyltransferase E(z) isoform X1 K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
E 125057972 polycomb protein EED K11462 EED; polycomb protein EED
E 125057344 polycomb protein suz12-B K11463 SUZ12; polycomb protein SUZ12
E 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D PR-DUB complex
E 125054180 ubiquitin carboxyl-terminal hydrolase calypso K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
E 125050882 polycomb protein Asx K11471 ASXL; additional sex combs-like protein
E 125055917 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E 125062793 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit-like K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E 125056415 host cell factor 1-like K14966 HCFC1; host cell factor 1
E 125055222 transcriptional repressor protein YY1-like isoform X1 K09201 YY; transcription factor YY
E 125058073 forkhead box protein K1 K09404 FOXK; forkhead box protein K
D Other PRC associated proteins
E 125051511 SAP30-binding protein K26267 SAP30BP; SAP30-binding protein
E 125048647 autism susceptibility gene 2 protein-like isoform X1 K26258 tay; tay bridge
C Sir proteins
C Other histone modification proteins
D 125058107 tudor domain-containing protein 3 K18404 TDRD3; tudor domain-containing protein 3
D 125062448 E3 ubiquitin-protein ligase UHRF1-like K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 125052701 barrier-to-autointegration factor K21870 BANF; barrier-to-autointegration factor
D 125053307 GATA zinc finger domain-containing protein 1 K23407 GATAD1; GATA zinc finger domain-containing protein 1
D 125059426 uncharacterized protein LOC125059426 isoform X1 K24550 BCAS3; breast carcinoma-amplified sequence 3
D 125050399 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
D 125058032 histone PARylation factor 1 K26250 HPF1; histone PARylation factor 1
D 125054240 protein UXT homolog K26537 UXT; protein UXT
D 125063615 PHD finger protein 14 isoform X1 K27397 PHF14; PHD finger protein 14
B Chromosome condensation proteins
C Condensin I
D 125049758 structural maintenance of chromosomes protein 2 K06674 SMC2; structural maintenance of chromosome 2
D 125052874 structural maintenance of chromosomes protein 4 K06675 SMC4; structural maintenance of chromosome 4
D 125057464 condensin complex subunit 2 K06676 BRRN1; condensin complex subunit 2
D 125053945 condensin complex subunit 1 isoform X1 K06677 YCS4; condensin complex subunit 1
D 125053934 condensin complex subunit 3 isoform X1 K06678 YCG1; condensin complex subunit 3
C Condensin II
D 125049758 structural maintenance of chromosomes protein 2 K06674 SMC2; structural maintenance of chromosome 2
D 125052874 structural maintenance of chromosomes protein 4 K06675 SMC4; structural maintenance of chromosome 4
C Other regulators of chromosome condensation
D 125057180 DNA topoisomerase 2 isoform X1 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
E 125053893 centromere protein S-like K11511 APITD1; centromere protein S
D CPC (chromosomal passenger complex)
E 125053708 aurora kinase B-like isoform X1 K11479 AURKB; aurora kinase B [EC:2.7.11.1]
E 125053709 aurora kinase B-like isoform X1 K11479 AURKB; aurora kinase B [EC:2.7.11.1]
D KMN network proteins
E MIS12 complex
E NDC80 complex
D Mis6 complex
D COMA complex
D NMS complex
E NDC80 complex
E MIND kinetochore complex
D MIS16-MIS18 complex
E 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D DASH complex
D CBF3 complex
E 125061479 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Others
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
E 125063067 mitotic spindle assembly checkpoint protein MAD1-like isoform X1 K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
E 125060236 mitotic spindle assembly checkpoint protein MAD2A K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
E 125053400 mitotic checkpoint serine/threonine-protein kinase BUB1 beta K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
E 125048739 mitotic checkpoint protein BUB3 K02180 BUB3; cell cycle arrest protein BUB3
D Motor proteins
E RZZ complex
F 125059522 centromere/kinetochore protein zw10 homolog K11578 ZW10; protein transport protein DSL1/ZW10
E Dynein complex
F 125050367 dynein heavy chain, cytoplasmic isoform X1 K10413 DYNC1H; dynein cytoplasmic 1 heavy chain
F 125061360 cytoplasmic dynein 2 heavy chain 1 K10414 DYNC2H; dynein cytoplasmic 2 heavy chain
F 125063179 cytoplasmic dynein 1 intermediate chain isoform X1 K10415 DYNC1I; dynein cytoplasmic 1 intermediate chain
F 125050789 cytoplasmic dynein 1 light intermediate chain 2 K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
E 125059607 kinesin-like protein Klp10A isoform X1 K10393 KIF2_24; kinesin family member 2/24
D Protein kinases
E 125053708 aurora kinase B-like isoform X1 K11479 AURKB; aurora kinase B [EC:2.7.11.1]
E 125053709 aurora kinase B-like isoform X1 K11479 AURKB; aurora kinase B [EC:2.7.11.1]
E 125054854 mitogen-activated protein kinase 1 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
E 125061728 serine/threonine-protein kinase polo K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D Others
E 125057318 pachytene checkpoint protein 2 homolog K22399 TRIP13; pachytene checkpoint protein 2
E 125055891 nuclear migration protein nudC K25866 NUDC; nuclear migration protein NudC
C Other centromeric chromatin formation proteins
D Shugoshin
D PP2A (protein phosphatase 2A)
E 125060622 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 125054405 serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 125063119 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 125059528 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 125061745 uncharacterized protein LOC125061745 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 125052873 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 125055385 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform-like K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
D 125053555 chromobox protein homolog 1-like K11585 CBX1; chromobox protein 1
D 125050839 chromobox protein homolog 1-like K11587 CBX5; chromobox protein 5
C MBPs (metylated DNA binding proteins)
D 125050199 methyl-CpG-binding domain protein 2 isoform X1 K11590 MBD2; methyl-CpG-binding domain protein 2
C Other heterochromatin formation proteins
D 125060237 transcriptional regulator ATRX homolog isoform X1 K10779 ATRX; transcriptional regulator ATRX
D 125053624 DNA (cytosine-5)-methyltransferase PliMCI-like isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 125062726 DNA (cytosine-5)-methyltransferase 1-like K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D 125049962 chromodomain-helicase-DNA-binding protein Mi-2 homolog isoform X1 K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
D 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D 125056554 homeotic protein spalt-major isoform X1 K19871 SALL; sal-like protein
B Gene silencing
C RISC (RNA-induced silencing complex)
D 125055228 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
D 125063334 piwi-like protein Siwi K02156 AUB; aubergine
D 125060860 piwi-like protein Ago3 K02156 AUB; aubergine
D 125061719 putative ATP-dependent RNA helicase Pl10 isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
C piRNA pathway
D 125063334 piwi-like protein Siwi K02156 AUB; aubergine
D 125060860 piwi-like protein Ago3 K02156 AUB; aubergine
D 125061616 ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 K18410 ASZ1; ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
D 125058593 ATP-dependent RNA helicase vasa isoform X1 K13982 DDX4; probable ATP-dependent RNA helicase DDX4 [EC:5.6.2.7]
D 125054413 probable RNA helicase armi isoform X1 K13983 MOV10L1; RNA helicase MOV10L1 [EC:5.6.2.5]
D 125057725 protein Gawky isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
D 125060195 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D 125052176 ATP-dependent RNA helicase me31b isoform X1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D 125048911 mitochondrial cardiolipin hydrolase-like K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
E 125055228 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
D RDRC (RNA-directed RNA polymerase complex)
D Other RNAi proteins
C microRNA pathway
D Microprocessor complex
E 125053749 microprocessor complex subunit DGCR8 isoform X1 K18419 DCGR8; microprocessor complex subunit DGCR8
E 125051563 ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RISC loading complex
E 125055228 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 125053723 interferon-inducible double-stranded RNA-dependent protein kinase activator A homolog isoform X1 K18420 TARBP2; RISC-loading complex subunit TARBP2
D Other miRNA pathway proteins
E 125058105 exportin-5 K14289 XPO5; exportin-5
E 125049872 RNA helicase Mov10l1-like isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
C Transposable elements
D 125058399 LOW QUALITY PROTEIN: putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125062025 LOW QUALITY PROTEIN: putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125050853 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125060454 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125061276 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125061460 putative nuclease HARBI1 isoform X1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125061608 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125062002 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125051667 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125058927 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125051094 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125050052 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125050810 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125054018 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125058367 putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125058388 LOW QUALITY PROTEIN: putative nuclease HARBI1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
D 125058528 putative nuclease HARBI1 isoform X1 K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
B Centrosome formation proteins
C Centriole proteins
D 125059928 centrosomal protein of 104 kDa K16458 CEP104; centrosomal protein CEP104
D 125060129 centrosomal protein of 164 kDa isoform X1 K16462 CEP164; centrosomal protein CEP164
D 125061164 caltractin-like K16465 CETN1; centrin-1
D 125058515 caltractin-like isoform X1 K10840 CETN2; centrin-2
D 125055674 poly [ADP-ribose] polymerase-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 125055672 poly [ADP-ribose] polymerase 1-like isoform X1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 125060869 group XIIA secretory phospholipase A2 K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
D 125058108 POC1 centriolar protein homolog A-like isoform X1 K16482 POC1; centriolar protein POC1
D 125052754 serologically defined colon cancer antigen 8 homolog K16488 SDCCAG8; serologically defined colon cancer antigen 8
D 125057180 DNA topoisomerase 2 isoform X1 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C Pericentriolar materials (PCM)
D Centriolar satellite
E 125063425 centrosomal protein of 290 kDa K16533 CEP290; centrosomal protein CEP290
E 125053273 centrosomal protein 20 K16535 FOPNL; lisH domain-containing protein FOPNL
E 125054427 protein hook K16536 HOOK3; protein HOOK3
E 125059635 partitioning defective protein 6 K06093 PARD6; partitioning defective protein 6
D Other PCM proteins
E 125063650 uncharacterized protein LOC125063650 K16547 NEDD1; protein NEDD1
E 125055199 LOW QUALITY PROTEIN: ornithine decarboxylase antizyme 1 K16548 OAZ1; ornithine decarboxylase antizyme 1
E 125058513 poly [ADP-ribose] polymerase tankyrase isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
C Cyclins
D 125057902 cyclin-A2-like K06627 CCNA; cyclin-A
D 125063228 G2/mitotic-specific cyclin-B2 K21770 CCNB2; G2/mitotic-specific cyclin-B2
D 125055717 G2/mitotic-specific cyclin-B3 isoform X1 K21771 CCNB3; G2/mitotic-specific cyclin-B3
D 125059556 G1/S-specific cyclin-E isoform X1 K06626 CCNE; G1/S-specific cyclin-E1
D 125052433 cyclin-Q K23964 CCNQ; cyclin-Q
C Kinases and associated factors
D 125054674 serine/threonine-protein kinase Aurora-2 K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D 125053977 cyclin-dependent kinase 1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
D 125049325 cyclin-dependent kinase 2-like isoform X1 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 125057027 casein kinase I K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
D 125052271 uncharacterized protein LOC125052271 isoform X1 K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
D 125051966 glycogen synthase kinase-3 beta-like isoform X1 K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
D 125048770 integrin-linked protein kinase K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
D 125061728 serine/threonine-protein kinase polo K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D 125053114 serine/threonine-protein kinase PLK4 K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
D 125055755 rho-associated protein kinase 2 isoform X1 K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]
D 125051824 serine/threonine-protein kinase SIK2 K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
D 125052544 cAMP-dependent protein kinase catalytic subunit 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
D 125061431 cAMP-dependent protein kinase catalytic subunit alpha-like K04345 PKA; protein kinase A [EC:2.7.11.11]
D 125061433 cAMP-dependent protein kinase catalytic subunit alpha-like K04345 PKA; protein kinase A [EC:2.7.11.11]
D 125061434 cAMP-dependent protein kinase catalytic subunit beta-like K04345 PKA; protein kinase A [EC:2.7.11.11]
D 125050890 cAMP-dependent protein kinase catalytic subunit 1-like K04345 PKA; protein kinase A [EC:2.7.11.11]
D Kinase anchoring protein
C Microtubules and associated factors
D gamma-tubulin ring complex
E 125059776 tubulin gamma-2 chain-like K10389 TUBG; tubulin gamma
E 125061232 gamma-tubulin complex component 2-like isoform X1 K16569 TUBGCP2; gamma-tubulin complex component 2
E 125061865 gamma-tubulin complex component 3-like K16570 TUBGCP3; gamma-tubulin complex component 3
E 125062130 gamma-tubulin complex component 4 isoform X1 K16571 TUBGCP4; gamma-tubulin complex component 4
E 125063650 uncharacterized protein LOC125063650 K16547 NEDD1; protein NEDD1
D Other tubulins
E 125056928 tubulin alpha chain-like isoform X1 K07374 TUBA; tubulin alpha
E 125057044 tubulin alpha chain K07374 TUBA; tubulin alpha
E 125062153 tubulin alpha chain-like K07374 TUBA; tubulin alpha
E 125062753 tubulin alpha-1 chain-like K07374 TUBA; tubulin alpha
E 125063188 tubulin alpha chain K07374 TUBA; tubulin alpha
E 125057033 tubulin beta chain K07375 TUBB; tubulin beta
E 125061298 tubulin beta chain-like K07375 TUBB; tubulin beta
E 125061308 tubulin beta chain-like K07375 TUBB; tubulin beta
E 125050041 tubulin beta-1 chain-like K07375 TUBB; tubulin beta
E 125050213 tubulin beta chain-like K07375 TUBB; tubulin beta
E 125050706 tubulin beta-1 chain K07375 TUBB; tubulin beta
E 125051415 tubulin beta chain-like K07375 TUBB; tubulin beta
E 125051416 tubulin beta-4B chain-like K07375 TUBB; tubulin beta
E 125051417 tubulin beta-4B chain K07375 TUBB; tubulin beta
D Dynactin complex
E 125058431 dynactin subunit 1 isoform X1 K04648 DCTN1; dynactin 1
E 125048822 dynactin subunit 2 K10424 DCTN2; dynactin 2
E 125060316 uncharacterized protein LOC125060316 K10425 DCTN3; dynactin 3
E 125063183 dynactin subunit 4 K10426 DCTN4; dynactin 4
E 125054238 dynactin subunit 5 K10427 DCTN5; dynactin 5
E 125052831 dynactin subunit 6 K10428 DCTN6; dynactin 6
E 125058519 alpha-centractin K16575 ACTR1; centractin
E 125051948 actin-related protein 10 K16576 ACTR10; actin-related protein 10
D BRISC complex
E 125052849 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
E 125056005 BRISC and BRCA1-A complex member 2-like isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
D Microtubule-associated proteins
E 125062170 CLIP-associating protein isoform X1 K16578 CLASP1_2; CLIP-associating protein 1/2
E 125059267 microtubule-associated protein RP/EB family member 1 isoform X1 K10436 MAPRE; microtubule-associated protein, RP/EB family
E 125049406 tubulin polymerization-promoting protein homolog isoform X1 K25867 TPPP; tubulin polymerization-promoting protein [EC:3.6.5.-]
E 125053965 GTP-binding protein 128up K06944 DRG1; developmentally-regulated GTP-binding protein 1 [EC:3.6.5.-]
E 125051151 developmentally-regulated GTP-binding protein 2 K27705 DRG2; developmentally-regulated GTP-binding protein 2 [EC:3.6.5.-]
C Augmin complex
C Centrosome duplication proteins
D Centriole replication proteins
E 125053761 calcium-binding protein E63-1 isoform X1 K02183 CALM; calmodulin
E 125062239 calmodulin isoform X1 K02183 CALM; calmodulin
E 125048588 calmodulin-like isoform X1 K02183 CALM; calmodulin
E 125061388 calmodulin-like protein 4 K02183 CALM; calmodulin
E 125051503 centrosomal protein of 97 kDa isoform X1 K16717 CEP97; centrosomal protein CEP97
E 125058515 caltractin-like isoform X1 K10840 CETN2; centrin-2
D Regulators of centriole replication
E 125052977 obg-like ATPase 1 K19788 OLA1; obg-like ATPase 1
E 125058741 F-box/WD repeat-containing protein 11 isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 125053114 serine/threonine-protein kinase PLK4 K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
E 125054757 GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 125052217 exportin-1 K14290 XPO1; exportin-1
D Other centrosome duplication proteins
E 125057779 ankyrin repeat domain-containing protein 17 isoform X1 K16726 ANKRD17; ankyrin repeat domain-containing protein 17
E 125053584 rho guanine nucleotide exchange factor 10-like protein isoform X1 K16727 ARHGEF10; Rho guanine nucleotide exchange factor 10
E 125055266 serine/threonine-protein kinase BRSK2 isoform X1 K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
E 125051103 cysteine and histidine-rich domain-containing protein morgana K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
E 125051663 protein crooked neck K12869 CRN; crooked neck
E 125052897 uncharacterized protein LOC125052897 K04402 GADD45; growth arrest and DNA-damage-inducible protein
E 125052971 golgin subfamily A member 1 isoform X1 K16731 GOLGA1; golgin subfamily A member 1
E 125061407 leishmanolysin-like peptidase isoform X1 K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
E 125052351 DNA replication licensing factor Mcm5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
E 125057081 origin recognition complex subunit 1 K02603 ORC1; origin recognition complex subunit 1
E 125063148 origin recognition complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
E 125051904 protein regulator of cytokinesis 1-like isoform X1 K16732 PRC1; Ase1/PRC1/MAP65 family protein
E 125048597 rac GTPase-activating protein 1-like K16733 RACGAP1; Rac GTPase-activating protein 1
E 125060831 enkurin domain-containing protein 1-like isoform X1 K27678 ENKD1; enkurin domain-containing protein 1
C Nde1-Su48 complex
D 125055127 microspherule protein 1 K11674 MCRS1; microspherule protein 1
C LINC complex
D 125050801 muscle-specific protein 300 kDa isoform X1 K19326 SYNE1; nesprin-1
C 3M complex
C Other centrosome associated proteins
D 125053798 fructose-bisphosphate aldolase-like isoform X1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D 125055742 fructose-bisphosphate aldolase isoform X1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D 125051003 alsin isoform X1 K04575 ALS2; amyotrophic lateral sclerosis 2 protein
D 125049971 adenomatous polyposis coli protein-like isoform X1 K02085 APC; adenomatosis polyposis coli protein
D 125054462 ADP-ribosylation factor-like protein 2 K07943 ARL2; ADP-ribosylation factor-like protein 2
D 125057905 protein abnormal spindle isoform X1 K16743 ASPM; abnormal spindle-like microcephaly-associated protein
D 125053594 bicaudal D-related protein homolog K16756 BICDL; BICD family-like cargo adapter
D 125051728 biogenesis of lysosome-related organelles complex 1 subunit 2 K16750 BLOC1S2; biogenesis of lysosome-related organelles complex 1 subunit 2
D 125050710 coiled-coil domain-containing protein 102A-like K16759 CCDC102; coiled-coil domain-containing protein 102
D 125062260 cdc42 homolog K04393 CDC42; cell division control protein 42
D 125054990 disks large 1 tumor suppressor protein isoform X1 K12076 DLG1; disks large protein 1
D 125053379 disks large homolog 2-like K12076 DLG1; disks large protein 1
D 125059265 exocyst complex component 7 isoform X1 K07195 EXOC7; exocyst complex component 7
D 125053519 flotillin-2 isoform X1 K07192 FLOT; flotillin
D 125062698 flotillin-1 isoform X1 K07192 FLOT; flotillin
D 125055751 probable E3 ubiquitin-protein ligase HERC2 isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D 125053736 DNA replication licensing factor Mcm2 isoform X1 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 125049461 DNA replication licensing factor Mcm3 isoform X1 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 125057065 paired box protein Pax-5 isoform X1 K15608 PAX2; paired box protein 2
D 125054562 ras-related protein Rab-8A-like isoform X1 K07901 RAB8A; Ras-related protein Rab-8A
D 125055643 uncharacterized protein LOC125055643 isoform X1 K21763 MAPKBP1; mitogen-activated protein kinase binding protein 1
D 125049866 fidgetin-like protein 1 isoform X1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D 125063358 putative methyltransferase C9orf114 K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
C Spindle formation proteins
D 125054674 serine/threonine-protein kinase Aurora-2 K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D 125051530 protein mini spindles K16803 CKAP5; cytoskeleton-associated protein 5
D 125059362 RNA transcription, translation and transport factor protein K15433 CGI99; RLL motif containing protein 1
D 125050507 exportin-2 K18423 CSE1; exportin-2 (importin alpha re-exporter)
D 125057589 guanylate kinase-associated protein mars K16804 DLGAP5; disks large-associated protein 5
D 125062621 G-protein-signaling modulator 2 K15837 GPSM2; G-protein signaling modulator 2
D 125059607 kinesin-like protein Klp10A isoform X1 K10393 KIF2_24; kinesin family member 2/24
D 125053765 kinesin-like protein Klp61F K10398 KIF11; kinesin family member 11
D 125055265 kinesin-like protein KIF23 K17387 KIF23; kinesin family member 23
D 125054711 protein claret segregational K10405 KIFC1; kinesin family member C1
D 125055054 importin subunit alpha-1-like K15043 KPNA2_7; importin subunit alpha-1/8
D 125063556 importin subunit alpha-7 K15042 KPNA5_6; importin subunit alpha-6/7
D 125056887 importin subunit beta-1 isoform X1 K14293 KPNB1; importin subunit beta-1
D 125059869 nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
D 125057945 nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
D 125049680 nuclear pore complex protein Nup160 homolog isoform X1 K14303 NUP160; nuclear pore complex protein Nup160
D 125063497 nuclear pore complex protein Nup205 K14310 NUP205; nuclear pore complex protein Nup205
D 125061718 Krueppel homolog 2 K20724 TMEM33; transmembrane protein 33
D 125052173 reticulon-1 isoform X1 K20721 RTN1; reticulon-1
D 125049018 lissencephaly-1 homolog K16794 PAFAH1B1; platelet-activating factor acetylhydrolase IB subunit alpha
D 125050503 protein Rae1 K14298 RAE1; mRNA export factor
D 125054757 GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
D 125054109 trichoplein keratin filament-binding protein K16811 TCHP; trichoplein keratin filament-binding protein
D 125053965 GTP-binding protein 128up K06944 DRG1; developmentally-regulated GTP-binding protein 1 [EC:3.6.5.-]
B Sister chromatid separation proteins
C Securin and associated proteins
C Separase
C APC/C complex
D 125051604 anaphase-promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
D 125056040 anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D 125056835 cell division cycle protein 27 homolog K03350 APC3; anaphase-promoting complex subunit 3
D 125061338 anaphase-promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
D 125056445 anaphase-promoting complex subunit 5 K03352 APC5; anaphase-promoting complex subunit 5
D 125055927 cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
D 125061418 anaphase-promoting complex subunit 10 isoform X1 K03357 APC10; anaphase-promoting complex subunit 10
D 125051047 anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
D 125055933 anaphase-promoting complex subunit 15-like K25228 APC15; anaphase-promoting complex subunit 15
D 125058943 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
C Aurora kinases
D 125054674 serine/threonine-protein kinase Aurora-2 K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D 125053708 aurora kinase B-like isoform X1 K11479 AURKB; aurora kinase B [EC:2.7.11.1]
D 125053709 aurora kinase B-like isoform X1 K11479 AURKB; aurora kinase B [EC:2.7.11.1]
D Regulators of Aurora kinases
E 125055802 LIM domain-containing protein jub K16682 AJUBA; LIM domain-containing protein
E 125052897 uncharacterized protein LOC125052897 K04402 GADD45; growth arrest and DNA-damage-inducible protein
E 125056382 breast cancer anti-estrogen resistance protein 1 isoform X1 K16832 NEDD9; enhancer of filamentation 1
E 125060595 protein phosphatase inhibitor 2-like K16833 PPP1R2; protein phosphatase inhibitor 2
C TACC proteins
C Polo kinases
D 125061728 serine/threonine-protein kinase polo K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D 125053114 serine/threonine-protein kinase PLK4 K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
C Early mitotic inhibitors
B Chromatin remodeling factors
C BAF complex
D 125055757 ATP-dependent helicase brm K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D 125053699 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A isoform X1 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D 125053730 SWI/SNF complex subunit SMARCC2 isoform X1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D 125054347 brahma-associated protein of 60 kDa K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D 125056413 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
D 125057293 actin-5C K05692 ACTB_G1; actin beta/gamma 1
D 125057294 actin, cytoplasmic A3a K05692 ACTB_G1; actin beta/gamma 1
D 125062224 actin-like protein 6A K11652 ACTL6B; actin-like protein 6B
D 125049898 B-cell CLL/lymphoma 7 protein family member A K25605 BCL7; B-cell CLL/lymphoma 7 protein
D 125053497 trithorax group protein osa isoform X1 K11653 ARID1; AT-rich interactive domain-containing protein 1
D 125050310 zinc finger protein ubi-d4 B isoform X1 K13196 DPF2; zinc finger protein ubi-d4
C PBAF complex
D 125055757 ATP-dependent helicase brm K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D 125053699 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A isoform X1 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D 125053730 SWI/SNF complex subunit SMARCC2 isoform X1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D 125054347 brahma-associated protein of 60 kDa K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D 125056413 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
D 125057293 actin-5C K05692 ACTB_G1; actin beta/gamma 1
D 125057294 actin, cytoplasmic A3a K05692 ACTB_G1; actin beta/gamma 1
D 125062224 actin-like protein 6A K11652 ACTL6B; actin-like protein 6B
D 125049898 B-cell CLL/lymphoma 7 protein family member A K25605 BCL7; B-cell CLL/lymphoma 7 protein
D 125063157 protein polybromo-1 isoform X1 K11757 PBRM1; protein polybromo-1
D 125059871 bromodomain-containing protein 7-like isoform X1 K11723 BRD7; bromodomain-containing protein 7
C GBAF(ncBAF) complex
D 125055757 ATP-dependent helicase brm K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D 125053730 SWI/SNF complex subunit SMARCC2 isoform X1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D 125054347 brahma-associated protein of 60 kDa K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D 125062224 actin-like protein 6A K11652 ACTL6B; actin-like protein 6B
D 125057293 actin-5C K05692 ACTB_G1; actin beta/gamma 1
D 125057294 actin, cytoplasmic A3a K05692 ACTB_G1; actin beta/gamma 1
D 125049898 B-cell CLL/lymphoma 7 protein family member A K25605 BCL7; B-cell CLL/lymphoma 7 protein
C CHRAC complex
D 125061148 chromatin-remodeling complex ATPase chain Iswi K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D 125059984 chromatin accessibility complex 16kD protein K11656 CHRAC1; chromatin accessibility complex protein 1
D 125052680 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C RSF complex
D 125061148 chromatin-remodeling complex ATPase chain Iswi K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C WICH complex
D 125061148 chromatin-remodeling complex ATPase chain Iswi K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C B-WICH complex
D 125061148 chromatin-remodeling complex ATPase chain Iswi K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D 125050344 protein DEK isoform X1 K17046 DEK; protein DEK
D 125057877 DNA excision repair protein ERCC-6-like K10841 ERCC6; DNA excision repair protein ERCC-6
D 125048787 unconventional myosin ID K10356 MYO1; myosin I
D 125048810 unconventional myosin IC isoform X1 K10356 MYO1; myosin I
D 125053550 myb-binding protein 1A-like protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 125052860 splicing factor 3B subunit 1 K12828 SF3B1; splicing factor 3B subunit 1
C NORC complex
D 125061148 chromatin-remodeling complex ATPase chain Iswi K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C BRF complex
D 125061148 chromatin-remodeling complex ATPase chain Iswi K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D 125057017 uncharacterized protein LOC125057017 isoform X1 K26167 BAZ2B; bromodomain adjacent to zinc finger domain protein 2B
C NuRD complex
D 125048758 histone deacetylase HDAC1 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D 125049962 chromodomain-helicase-DNA-binding protein Mi-2 homolog isoform X1 K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
D 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D 125054385 metastasis-associated protein MTA3 isoform X1 K11660 MTA; metastasis-associated protein MTA
C NuRF complex
D 125052925 nucleosome-remodeling factor subunit NURF301 isoform X1 K11728 BPTF; nucleosome-remodeling factor subunit BPTF
D 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D 125062177 chromatin complexes subunit BAP18-like isoform X1 K23406 BAP18; chromatin complexes subunit BAP18
D 125062178 chromatin complexes subunit BAP18-like isoform X1 K23406 BAP18; chromatin complexes subunit BAP18
D 125062179 chromatin complexes subunit BAP18-like isoform X1 K23406 BAP18; chromatin complexes subunit BAP18
D 125062180 chromatin complexes subunit BAP18-like isoform X1 K23406 BAP18; chromatin complexes subunit BAP18
D 125062182 chromatin complexes subunit BAP18-like isoform X1 K23406 BAP18; chromatin complexes subunit BAP18
D 125056598 uncharacterized protein LOC125056598 isoform X1 K23406 BAP18; chromatin complexes subunit BAP18
C NuRF complex (fruit fly)
D 125061148 chromatin-remodeling complex ATPase chain Iswi K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D 125052925 nucleosome-remodeling factor subunit NURF301 isoform X1 K11728 BPTF; nucleosome-remodeling factor subunit BPTF
D 125060838 chromatin assembly factor 1 p55 subunit K10752 RBBP4; histone-binding protein RBBP4
D 125053260 inorganic pyrophosphatase K11726 NURF38; nucleosome-remodeling factor 38 kDa subunit [EC:3.6.1.1]
C CERF complex
C SRCAP complex
D 125055526 actin-related protein 6 K11662 ACTR6; actin-related protein 6
D 125056033 ruvB-like helicase 1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D 125061102 ruvB-like 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D 125052420 DNA methyltransferase 1-associated protein 1 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
D 125054835 YEATS domain-containing protein 4 K11341 YEATS4; YEATS domain-containing protein 4
D 125060948 zinc finger HIT domain-containing protein 1 K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
C INO80 complex
D 125051720 chromatin-remodeling ATPase INO80 K11665 INO80; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D 125054893 INO80 complex subunit B K11666 INO80B; INO80 complex subunit B
D 125057881 INO80 complex subunit C K11667 INO80C; INO80 complex subunit C
D 125053591 uncharacterized protein LOC125053591 K11669 INO80E; INO80 complex subunit E
D 125056033 ruvB-like helicase 1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D 125061102 ruvB-like 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D 125060404 actin-related protein 5 K11672 ACTR5; actin-related protein 5
D 125050435 actin-related protein 8 K11673 ACTR8; actin-related protein 8
D 125055127 microspherule protein 1 K11674 MCRS1; microspherule protein 1
C INO80 complex (yeast)
D 125051720 chromatin-remodeling ATPase INO80 K11665 INO80; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D 125057881 INO80 complex subunit C K11667 INO80C; INO80 complex subunit C
D 125049557 HMG1/2-like protein K11680 NHP10; non-histone protein 10
D 125056033 ruvB-like helicase 1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D 125061102 ruvB-like 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D 125060404 actin-related protein 5 K11672 ACTR5; actin-related protein 5
D 125050435 actin-related protein 8 K11673 ACTR8; actin-related protein 8
C RSC complex
C SWI/SNF complex
D 125053699 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A isoform X1 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
C SWR1 complex
D 125057293 actin-5C K05692 ACTB_G1; actin beta/gamma 1
D 125057294 actin, cytoplasmic A3a K05692 ACTB_G1; actin beta/gamma 1
D 125056033 ruvB-like helicase 1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D 125061102 ruvB-like 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D 125055526 actin-related protein 6 K11662 ACTR6; actin-related protein 6
D 125054835 YEATS domain-containing protein 4 K11341 YEATS4; YEATS domain-containing protein 4
D 125060948 zinc finger HIT domain-containing protein 1 K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
D 125052420 DNA methyltransferase 1-associated protein 1 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
C ASTRA complex
D 125050856 transcription-associated protein 1 isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
D 125056033 ruvB-like helicase 1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D 125061102 ruvB-like 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
C Other chromatin remodeling factors
D 125062184 transcriptional repressor CTCFL-like isoform X1 K23195 CTCF; transcriptional repressor CTCF
D 125048976 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 homolog K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
D 125061841 ubinuclein-1 isoform X1 K17492 UBN; ubinuclein
D 125052493 PWWP domain-containing protein 2A-like K26100 PWWP2; PWWP domain-containing protein 2
D 125058514 protein strawberry notch-like isoform X1 K26273 SBNO; protein strawberry notch
D 125048714 high mobility group protein D K26796 HmgD_Z; high mobility group protein D/Z
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AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
C HU (heat unstable protein)
C IHF (integration host factor)
C Other nucleoid associated proteins
B Chromosome partitioning proteins
C MukBEF complex
C Condensin-like complex
C Divisome proteins
C Inhibitors of FtsZ assembly
C Other chromosome partitioning proteins
D 125048479 iron-sulfur protein NUBPL K03593 mrp; ATP-binding protein involved in chromosome partitioning
D 125059851 protein adenylyltransferase Fic K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 30, 2024