+F	Repair protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Pieris napi (green-veined white)</h2>
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A<b>Eukaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      125049988 DNA oxidative demethylase ALKBH2-like	K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33] 
D      125052049 activating signal cointegrator 1 complex subunit 3	K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] 
D      125059910 deoxyribodipyrimidine photo-lyase	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        125053986 single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        125057043 N-glycosylase/DNA lyase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
E        125058031 recombination repair protein 1-like	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
D      Long Patch-BER factors
E        DNA polymerase delta complex
F          125053005 DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
F          125049108 DNA polymerase delta subunit 2 isoform X1	K02328 POLD2; DNA polymerase delta subunit 2 
E        DNA polymerase epsilon complex
F          125054559 DNA polymerase epsilon catalytic subunit 1	K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] 
F          125053206 DNA polymerase epsilon subunit 2	K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 
F          125052680 DNA polymerase epsilon subunit 3	K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] 
F          125060169 DNA polymerase epsilon subunit 4	K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] 
E        125056951 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        125050617 flap endonuclease 1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] 
E        125050211 DNA ligase 1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
D      Short Patch-BER factors
E        125052784 DNA polymerase beta-like isoform X1	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
E        125060178 DNA ligase 3	K10776 LIG3; DNA ligase 3 [EC:6.5.1.1] 
D      Other BER factors
E        125058790 probable tyrosyl-DNA phosphodiesterase	K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] 
E        125057287 aprataxin	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
E        125048738 aprataxin and PNK-like factor isoform X1	K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] 
E        125048868 uncharacterized protein F21D5.5	K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
E        125058035 high mobility group protein DSP1-like isoform X1	K10802 HMGB1; high mobility group protein B1 
E        125055674 poly [ADP-ribose] polymerase-like	K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
E        125055672 poly [ADP-ribose] polymerase 1-like isoform X1	K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        XPC-HR23B-CETN2 complex
F          125052851 UV excision repair protein RAD23 homolog A	K10839 RAD23; UV excision repair protein RAD23 
F          125058515 caltractin-like isoform X1	K10840 CETN2; centrin-2 
E        Cul4-DDB2 complex
F          125061084 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          125059943 cullin-4A	K10609 CUL4; cullin 4 
F          125050459 DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
E        NER4 complex
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase II complex
F          125062562 DNA-directed RNA polymerase II subunit RPB1	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          125055801 DNA-directed RNA polymerase II subunit RPB2	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          125054416 DNA-directed RNA polymerase II subunit RPB3	K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 
F          125054187 DNA-directed RNA polymerase II subunit Rpb4	K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 
F          125059428 DNA-directed RNA polymerases I, II, and III subunit RPABC1	K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 
F          125053508 DNA-directed RNA polymerases I, II, and III subunit RPABC2	K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 
F          125054563 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          125058779 DNA-directed RNA polymerases I, II, and III subunit RPABC3	K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 
F          125063638 DNA-directed RNA polymerase II subunit RPB9	K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 
F          125057144 DNA-directed RNA polymerases I, II, and III subunit RPABC5	K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 
F          125054612 DNA-directed RNA polymerase II subunit RPB11	K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 
F          125054277 DNA-directed RNA polymerases I, II, and III subunit RPABC4	K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 
E        Cul4-CSA complex
F          125061084 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          125059943 cullin-4A	K10609 CUL4; cullin 4 
F          125050459 DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
E        Other TCR factor
F          125057877 DNA excision repair protein ERCC-6-like	K10841 ERCC6; DNA excision repair protein ERCC-6 
F          125051430 transcription elongation factor 1 homolog	K25829 ELOF1; transcription elongation factor 1 
D      TFIIH complex
E        125049967 general transcription and DNA repair factor IIH helicase subunit XPB	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] 
E        125050157 general transcription and DNA repair factor IIH helicase subunit XPD	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        125051632 general transcription factor IIH subunit 1	K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 
E        125048804 general transcription factor IIH subunit 2	K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 
E        125063760 general transcription factor IIH subunit 3	K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 
E        125057498 LOW QUALITY PROTEIN: general transcription factor IIH subunit 4	K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 
E        125060949 general transcription factor IIH subunit 5	K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit 
E        125050086 cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        125053780 cyclin-H	K06634 CCNH; cyclin H 
E        125059343 CDK-activating kinase assembly factor MAT1	K10842 MNAT1; CDK-activating kinase assembly factor MAT1 
D      RPA (replication factor A)
E        125049009 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        125048950 replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
D      Other NER factors
E        125059564 DNA repair protein complementing XP-A cells homolog	K10847 XPA; DNA-repair protein complementing XP-A cells 
E        125063360 DNA excision repair protein ERCC-1 isoform X1	K10849 ERCC1; DNA excision repair protein ERCC-1 
E        125052338 DNA repair endonuclease XPF isoform X1	K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] 
E        125050211 DNA ligase 1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
E        125059762 MMS19 nucleotide excision repair protein homolog	K15075 MET18; DNA repair/transcription protein MET18/MMS19 
E        125056419 cullin-3-B isoform X1	K03869 CUL3; cullin 3 
E        125056275 cullin-5	K10612 CUL5; cullin 5 
E        125059609 elongin-C isoform X1	K03872 ELOC; elongin-C 
E        125049466 elongin-B	K03873 ELOB; elongin-B 
E        125060102 transcription elongation factor B polypeptide 3-like	K15076 ELOA; elongin-A 
E        125052889 protein lingerer isoform X1	K26545 UBAP2; ubiquitin-associated protein 2 
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
E        125063080 DNA mismatch repair protein Msh2	K08735 MSH2; DNA mismatch repair protein MSH2 
E        125053484 probable DNA mismatch repair protein Msh6	K08737 MSH6; DNA mismatch repair protein MSH6 
D      MutL homologs
E        125054364 DNA mismatch repair protein Mlh1 isoform X1	K08734 MLH1; DNA mismatch repair protein MLH1 
E        125048836 mismatch repair endonuclease PMS2 isoform X1	K10858 PMS2; DNA mismatch repair protein PMS2 
E        125060523 uncharacterized protein LOC125060523	K08739 MLH3; DNA mismatch repair protein MLH3 
D      DNA polymerase delta complex
E        125053005 DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
E        125049108 DNA polymerase delta subunit 2 isoform X1	K02328 POLD2; DNA polymerase delta subunit 2 
D      RPA (replication factor A)
E        125049009 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        125048950 replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
D      RFC (replication factor C)
E        125050937 replication factor C subunit 1	K10754 RFC1; replication factor C subunit 1 
E        125056486 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
E        125061796 replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
E        125052480 replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
E        125049089 replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
D      Other MMR factors
E        125056951 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        125048873 exonuclease 1	K10746 EXO1; exonuclease 1 [EC:3.1.-.-] 
E        125058035 high mobility group protein DSP1-like isoform X1	K10802 HMGB1; high mobility group protein B1 
E        125050211 DNA ligase 1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      MRN(MRX) complex
E        125057646 double-strand break repair protein MRE11	K10865 MRE11; double-strand break repair protein MRE11 
E        125048627 DNA repair protein RAD50	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA1-core complex
D      BRCA1-A complex
E        125056005 BRISC and BRCA1-A complex member 2-like isoform X1	K12173 BRE; BRCA1-A complex subunit BRE 
E        125052849 lys-63-specific deubiquitinase BRCC36-like	K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] 
D      BRCA1-B complex
E        125061741 Fanconi anemia group J protein homolog isoform X1	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
D      BRCA1-C complex
E        125057646 double-strand break repair protein MRE11	K10865 MRE11; double-strand break repair protein MRE11 
E        125048627 DNA repair protein RAD50	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA complex
E        125049041 DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
D      RecA family proteins
E        125049041 DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
D      Rad52 family proteins
D      Rad54 family proteins
E        125058299 DNA repair and recombination protein RAD54-like	K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] 
D      RecQ family DNA helicases
E        125057939 ATP-dependent DNA helicase Q1-like	K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] 
E        125050121 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        125052783 ATP-dependent helicase SGS1-like	K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4] 
D      Bloom's syndrome complex (BTR)
E        125050121 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        125051555 DNA topoisomerase 3-beta-1 isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        125049715 DNA topoisomerase 3-alpha isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        125060823 recQ-mediated genome instability protein 1-like isoform X1	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      RPA (replication factor A)
E        125049009 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        125048950 replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
D      Protein phosphatase 4
E        125053522 serine/threonine-protein phosphatase 4 catalytic subunit	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        125057486 serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
D      AP-5 complex
D      SMC5-SMC6 complex
E        125059327 structural maintenance of chromosomes protein 5 isoform X1	K22803 SMC5; structural maintenance of chromosomes protein 5 
E        125059552 structural maintenance of chromosomes protein 6	K22804 SMC6; structural maintenance of chromosomes protein 6 
E        125060162 uncharacterized protein LOC125060162	K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] 
E        125056582 E3 SUMO-protein ligase NSE2-like	K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] 
E        125060582 non-structural maintenance of chromosomes element 3 homolog	K22823 NSMCE3; non-structural maintenance of chromosomes element 3 
E        125058475 EP300-interacting inhibitor of differentiation 3-like	K22825 NSMCE4; non-structural maintenance of chromosomes element 4 
D      Other HR factors
E        125051173 exonuclease 3'-5' domain-containing protein 2	K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] 
E        125062525 structure-specific endonuclease subunit SLX1 homolog	K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] 
E        125061664 flap endonuclease GEN isoform X1	K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] 
E        125054433 spatacsin	K19026 SPG11; spatacsin 
E        125053663 zinc finger FYVE domain-containing protein 26 homolog isoform X1	K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26 
E        125050565 mortality factor 4-like protein 1	K11339 MORF4L1; mortality factor 4-like protein 1 
E        125049866 fidgetin-like protein 1 isoform X1	K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] 
E        125048991 tonsoku-like protein	K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 
E        125063489 biorientation of chromosomes in cell division protein 1-like 1 isoform X1	K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 
C    NHEJ (non-homologous end-joining)
D      DNA-PK complex
D      MRX complex
E        125057646 double-strand break repair protein MRE11	K10865 MRE11; double-strand break repair protein MRE11 
E        125048627 DNA repair protein RAD50	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      DNA Ligase 4 complex
D      X-family DNA polymerases
E        125052784 DNA polymerase beta-like isoform X1	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
D      Other NHEJ factors
E        125057287 aprataxin	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
E        125048738 aprataxin and PNK-like factor isoform X1	K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] 
C    FA (Fanconi anemia) pathway
D      FA core complex
E        125063341 Fanconi anemia group M protein isoform X1	K10896 FANCM; fanconi anemia group M protein 
D      FA core complex binding factors
E        125053893 centromere protein S-like	K11511 APITD1; centromere protein S 
E        125048716 centromere protein X-like	K15360 STRA13; centromere protein X 
E        125050479 ubiquitin-conjugating enzyme E2 T-like	K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] 
D      Bloom's syndrome complex (BTR)
E        125050121 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        125051555 DNA topoisomerase 3-beta-1 isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        125049715 DNA topoisomerase 3-alpha isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        125060823 recQ-mediated genome instability protein 1-like isoform X1	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      FANCD2-I complex
E        125060118 Fanconi anemia group D2 protein	K10891 FANCD2; fanconi anemia group D2 protein 
D      Downstream FA components
E        125061741 Fanconi anemia group J protein homolog isoform X1	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
D      Other FA pathway factors
E        125049041 DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
E        125048493 probable ubiquitin carboxyl-terminal hydrolase 9	K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] 
E        125059230 WD repeat-containing protein 48 homolog	K15361 WDR48; WD repeat-containing protein 48 
C    Other DSBR factors
D      Protein phosphatase 6
E        125055753 serine/threonine-protein phosphatase 6 catalytic subunit	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
D      Ubiquitin ligases
E        125052773 E3 ubiquitin-protein ligase rnf8-like isoform X1	K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] 
E        125061901 E3 ubiquitin-protein ligase RNF169-like	K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31] 
E        125055751 probable E3 ubiquitin-protein ligase HERC2 isoform X1	K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
D      Others
E        125050399 gastrulation defective protein 1 homolog	K24752 WDR70; WD repeat-containing protein 70 
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
D      125049858 DNA polymerase eta	K03509 POLH; DNA polymerase eta [EC:2.7.7.7] 
D      125052865 DNA polymerase iota	K03510 POLI; DNA polymerase iota [EC:2.7.7.7] 
D      125060238 DNA repair protein Rev1	K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] 
C    B-family DNA polymerases
C    A-family DNA polymerase
C    Rad6 epistasis group
D      125052070 ubiquitin-conjugating enzyme E2-17 kDa	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      125057147 ubiquitin-conjugating enzyme E2 variant 2	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      125059572 ubiquitin-conjugating enzyme E2 N	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
C    Other TLS factors
D      125056951 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
D      125059345 germ cell nuclear acidic protein	K26957 GCNA; germ cell nuclear acidic protein 
B  Check point factors
C    Rad9-Hus1-Rad1 complex
D      125059155 checkpoint protein HUS1	K10903 HUS1; HUS1 checkpoint protein 
D      125053570 cell cycle checkpoint protein RAD1 isoform X1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    HRAD17(Rad24)-RFC complex
D      125056486 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
D      125061796 replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
D      125052480 replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
D      125049089 replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
C    Rad17-Mec3-Ddc1 complex
D      125053570 cell cycle checkpoint protein RAD1 isoform X1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    FPC (fork protection complex)
D      125063636 protein timeless homolog	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      125052913 TIMELESS-interacting protein	K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 
C    Triple T complex
C    BAG6-UBL4A-GET4 complex
D      125055100 Golgi to ER traffic protein 4 homolog	K23387 GET4; golgi to ER traffic protein 4 
D      125055443 Golgi to ER traffic protein 4 homolog isoform X1	K23387 GET4; golgi to ER traffic protein 4 
C    Other check point factors
D      125048953 ovarian-specific serine/threonine-protein kinase Lok-like	K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
D      125053634 14-3-3 protein zeta isoform X1	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      125053604 14-3-3 protein epsilon	K06630 YWHAE; 14-3-3 protein epsilon 
D      125055878 protein sickie isoform X1	K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] 
D      125055380 wee1-like protein kinase 2	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      125057461 plastin-2-like	K17336 PLS3; plastin-3 
D      125058685 plastin-2-like	K17336 PLS3; plastin-3 
D      125049742 protein downstream neighbor of son homolog	K22422 DONSON; protein downstream neighbor of Son 
D      125060263 vacuolar protein sorting-associated protein 4	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      125050440 replication stress response regulator SDE2	K25059 SDE2; replication stress response regulator SDE2 
B  Other factors with a suspected DNA repair function
C    DNA polymerases
D      125063625 DNA polymerase theta	K02349 POLQ; DNA polymerase theta [EC:2.7.7.7] 
D      125053550 myb-binding protein 1A-like protein	K02331 POL5; DNA polymerase phi [EC:2.7.7.7] 
C    Nucleases
D      125059874 uncharacterized protein LOC125059874	K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] 
D      125059642 uncharacterized protein LOC125059642	K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] 
C    Helicases
C    PSO4 complex
D      125049470 pre-mRNA-processing factor 19	K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] 
D      125063345 cell division cycle 5-like protein	K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 
D      125055594 pre-mRNA-splicing factor SPF27	K12861 BCAS2; pre-mRNA-splicing factor SPF27 
D      125058061 pleiotropic regulator 1	K12862 PLRG1; pleiotropic regulator 1 
C    Modulation of nucleotide pools
D      125057836 oxidized purine nucleoside triphosphate hydrolase-like	K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] 
D      125056327 8-oxo-dGDP phosphatase NUDT18	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      125051804 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      125052698 ribonucleoside-diphosphate reductase large subunit	K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 
D      125059777 ribonucleoside-diphosphate reductase subunit M2	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
#
A<b>Prokaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      125059910 deoxyribodipyrimidine photo-lyase	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        125053986 single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        125055932 DNA-3-methyladenine glycosylase 1-like	K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] 
D      AP endonucleases
D      RecJ
D      DNA ligase
D      DNA polymerase I
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase complex (RNAP)
E        TRCF (transcription-repair coupling factor)
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
D      Molecular matchmaker
D      Strand discrimination factor
D      DNA exonucleases
D      DNA polymerase III holoenzyme
D      DNA ligase
D      Other MMR factors
E        125061283 single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      RecBC pathway proteins
D      RecFOR pathway proteins
D      AddAB pathway proteins
D      Other HR factor
D      Archaeal homologous recombinant proteins
C    NHEJ (non-homologous end-joining)
D      Two-component NHEJ DNA repair complex
D      SHIIR (short-homology-independent illegitimate recombination)
E        Facilitator
E        Supressor
D      SHDIR (short-homology-dependent illegitimate recombination)
E        RecET pathway
E        Facilitator
E        Supressor
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
C    Other SOS response factors
D      125061283 single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  Other factors with a suspected DNA repair function
C    DNA polymerase
C    DNA helicases
C    Modulation of nucleotide pools
D      125051804 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
C    Others
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#Last updated: March 29, 2024