+D
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Transfer RNA Biogenesis - Pseudomonas aeruginosa NCGM2.S1
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
C CCA adding factors
D NCGM2_5603 cca; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D NCGM2_1011 hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D NCGM2_4261 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D NCGM2_1742 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D NCGM2_1036 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D NCGM2_5187 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NCGM2_4622 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D NCGM2_2698 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D NCGM2_0461 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D NCGM2_4831 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NCGM2_1770 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D NCGM2_1681 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D NCGM2_3781 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCGM2_3628 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NCGM2_2699 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D NCGM2_5023 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D NCGM2_4989 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D NCGM2_3777 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NCGM2_3776 pheT; phenylalanyl-tRNA synthetase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D NCGM2_5340 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCGM2_5535 tyrZ; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCGM2_1164 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D NCGM2_0431 dtD; D-tyrosyl-tRNA deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D NCGM2_2192 putative HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D NCGM2_4422 putative HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D NCGM2_5547 putative HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
D NCGM2_5179 hypothetical protein K06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D NCGM2_5817 trmB; tRNA (guanine-N(7))-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D NCGM2_4524 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D NCGM2_4237 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D NCGM2_0796 truB; tRNA pseudouridine 55 synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D NCGM2_4757 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D NCGM2_3039 iscS; putative pyridoxal-phosphate dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D NCGM2_5001 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D NCGM2_0021 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D NCGM2_0575 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D NCGM2_6356 trmE; tRNA modification GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D NCGM2_6353 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D NCGM2_2533 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D NCGM2_5932 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D NCGM2_6358 rnpA; ribonuclease P K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D NCGM2_4653 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D NCGM2_6099 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D NCGM2_2180 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D NCGM2_5603 cca; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D NCGM2_1011 hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D NCGM2_3971 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D NCGM2_0058 RNA 2'-phosphotransferase-like protein K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D NCGM2_0998 putative ABC transporter ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D NCGM2_5187 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NCGM2_1742 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D NCGM2_5340 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCGM2_5535 tyrZ; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCGM2_1164 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D NCGM2_3781 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCGM2_1036 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D NCGM2_4831 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NCGM2_1681 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D NCGM2_5023 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D NCGM2_4622 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D NCGM2_3628 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NCGM2_1770 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NCGM2_0009 glyQ; glycyl-tRNA synthetase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D NCGM2_0008 glyS; glycyl-tRNA synthetase subunit beta K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D NCGM2_2699 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D NCGM2_4261 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D NCGM2_2698 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D NCGM2_0461 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D NCGM2_3777 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NCGM2_3776 pheT; phenylalanyl-tRNA synthetase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D NCGM2_4989 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D NCGM2_0816 yadB; glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D NCGM2_0431 dtD; D-tyrosyl-tRNA deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D NCGM2_4708 ybaK; hypothetical protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D NCGM2_2756 hypothetical protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D NCGM2_4951 cumB; hypothetical protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D NCGM2_3889 yjbN; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D NCGM2_0676 yhdG; hypothetical protein K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D NCGM2_4252 hypothetical protein K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D NCGM2_5179 hypothetical protein K06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D NCGM2_1502 yecO; hypothetical protein K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D NCGM2_3010 hypothetical protein K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D NCGM2_1501 yecP; hypothetical protein K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D NCGM2_0742 smtA; hypothetical protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D NCGM2_0820 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D NCGM2_5817 trmB; tRNA (guanine-N(7))-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D NCGM2_4876 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D NCGM2_6356 trmE; tRNA modification GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D NCGM2_5004 putative methyltransferase K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D NCGM2_0382 trmH; putative rRNA methylase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D NCGM2_4524 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D NCGM2_4237 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D NCGM2_0796 truB; tRNA pseudouridine 55 synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D NCGM2_4757 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D NCGM2_3018 putative pseudouridylate synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D NCGM2_4369 rluA; pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D NCGM2_3642 trmU; tRNA(5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D NCGM2_2066 ydaO; ATPase K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D NCGM2_1860 yrkI; hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D NCGM2_2453 cell developmental protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D NCGM2_3623 hypothetical protein K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D NCGM2_3622 hypothetical protein K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D NCGM2_3621 dsrE; hypothetical protein K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D NCGM2_3624 hypothetical protein K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D NCGM2_4999 icsA; putative iron-binding protein K13628 iscA; iron-sulfur cluster assembly protein
D NCGM2_3039 iscS; putative pyridoxal-phosphate dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D NCGM2_5001 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D NCGM2_1485 hypothetical protein K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D NCGM2_6353 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D NCGM2_0575 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D NCGM2_2694 miaE; hypothetical protein K06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]
D NCGM2_4595 mnmC; 5-methylaminomethyl-2-thiouridine methyltransferase K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D NCGM2_5011 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D NCGM2_1783 hypothetical protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D NCGM2_3683 ptpS; putative 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D NCGM2_1782 radical activating enzyme K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D NCGM2_3900 queF; 7-cyano-7-deazaguanine reductase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D NCGM2_0570 yjeS; putative iron-sulfur cluster-binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D NCGM2_2533 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D NCGM2_2534 ybbB; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D NCGM2_5010 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D NCGM2_0392 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D NCGM2_4769 mesJ; hypothetical protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D NCGM2_4816 yeaZ; hypothetical protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D NCGM2_0021 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D NCGM2_5607 gcp; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D NCGM2_0572 hypothetical protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D NCGM2_2037 hypothetical protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C NCGM2_0585 rnr; exoribonuclease RNase R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C NCGM2_0799 pnp; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 23, 2026