+C Two-component system KO
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Two-Component System - Pseudomonas orientalis
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C BOP93_25865 phosphate regulon sensor histidine kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C BOP93_25860 phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
C BOP93_19615 histidine kinase K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C BOP93_19620 DNA-binding response regulator K07660 phoP; two-component system, OmpR family, response regulator PhoP
B EnvZ-OmpR (osmotic stress response)
C BOP93_01235 two-component sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C BOP93_01230 two-component system response regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C BOP93_19635 two-component sensor histidine kinase K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C BOP93_19640 DNA-binding response regulator K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C BOP93_20355 DNA-binding response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C BOP93_23985 two-component system sensor histidine kinase CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C BOP93_23990 two-component system response regulator CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C BOP93_04570 two-component sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C BOP93_07565 two-component sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C BOP93_16850 two-component sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C BOP93_04575 DNA-binding response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C BOP93_07570 DNA-binding response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C BOP93_16845 DNA-binding response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C BOP93_00970 response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
C BOP93_17990 two-component sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C BOP93_17995 DNA-binding response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C BOP93_07950 histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C BOP93_07955 DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C BOP93_06815 histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C BOP93_06810 DNA-binding response regulator K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
C BOP93_13980 two-component sensor histidine kinase K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
C BOP93_13985 DNA-binding response regulator K18073 parR; two-component system, OmpR family, response regulator ParR
B AdeS-AdeR
C BOP93_13075 two-component sensor histidine kinase K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
C BOP93_13070 DNA-binding response regulator K18144 adeR; two-component system, OmpR family, response regulator AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C BOP93_11205 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C BOP93_11200 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C BOP93_14430 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C BOP93_08660 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C BOP93_20825 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C BOP93_19055 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C BOP93_09280 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
C BOP93_04865 DNA-binding response regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
B BarA-UvrY (central carbon metabolism)
C BOP93_15385 hybrid sensor histidine kinase/response regulator K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C BOP93_09570 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C BOP93_08240 hybrid sensor histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C BOP93_09540 hybrid sensor histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C BOP93_05570 DNA-binding response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA
C BOP93_08245 DNA-binding response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA
C BOP93_09535 DNA-binding response regulator K07690 evgA; two-component system, NarL family, response regulator EvgA
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
C BOP93_02995 PAS domain-containing sensor histidine kinase K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]
C BOP93_03010 DNA-binding response regulator K27077 pprB; two-component system, NarL family, response regulator PprB
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C BOP93_25320 DNA-binding response regulator K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C BOP93_01585 PAS domain-containing sensor histidine kinase K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C BOP93_01580 nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C BOP93_22100 response regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C BOP93_20785 two-component sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C BOP93_01350 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C BOP93_01345 Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C BOP93_20790 DNA-binding response regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
C BOP93_00425 PAS domain-containing sensor histidine kinase K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
C BOP93_00430 sigma-54-dependent Fis family transcriptional regulator K11384 algB; two-component system, NtrC family, response regulator AlgB
B HupT-HupR (hydrogenase synthesis regulation)
C BOP93_12280 formyl transferase K19640 hypX; putative two-component system protein, hydrogenase maturation factor HypX/HoxX
B Unclassified
C BOP93_05325 hybrid sensor histidine kinase/response regulator K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C BOP93_05330 histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C BOP93_18125 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C BOP93_09625 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C BOP93_18135 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C BOP93_09615 two-component system response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C BOP93_18120 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C BOP93_12610 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C BOP93_09650 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C BOP93_04610 chemotaxis protein CheW K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C BOP93_19680 chemotaxis protein CheW K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C BOP93_18060 chemotaxis protein CheW K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
C BOP93_24480 hybrid sensor histidine kinase/response regulator K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C BOP93_24500 pilus assembly protein PilG K02657 pilG; twitching motility two-component system response regulator PilG
C BOP93_24495 two-component system response regulator K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
C BOP93_05855 hybrid sensor histidine kinase/response regulator K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
C BOP93_05865 diguanylate cyclase response regulator K11444 wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65]
C BOP93_05860 chemotaxis-specific protein-glutamate methylesterase CheB K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
B Cph1-Rcp1 (light response)
C BOP93_21545 histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
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ACell cycle family
B PleC-PleD (cell fate control)
C BOP93_12155 response regulator K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
C BOP93_12600 hypothetical protein K13589 cpdR; two-component system, cell cycle response regulator CpdR
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C BOP93_18265 PAS domain-containing sensor histidine kinase K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C BOP93_18260 sigma-54-dependent Fis family transcriptional regulator K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
C BOP93_05450 two-component sensor histidine kinase K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
C BOP93_05445 Fis family transcriptional regulator K17061 aauR; two-component system, response regulator AauR
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C BOP93_03980 histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C BOP93_03985 two-component system response regulator K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C BOP93_08225 hybrid sensor histidine kinase/response regulator K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
C BOP93_08600 hybrid sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
C BOP93_18215 histidine kinase K20976 hptB; histidine phosphotransfer protein HptB
C BOP93_18220 fused response regulator/phosphatase K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator
B PdtaS-PdtaR
B NasS-NasT
C BOP93_19070 nitrate transporter K22067 nasS; two-component system, oxyanion-binding sensor
C BOP93_19075 response regulator K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
C BOP93_22680 hybrid sensor histidine kinase/response regulator K20971 ladS; two-component system, sensor histidine kinase LadS
C BOP93_11895 hybrid sensor histidine kinase/response regulator K20971 ladS; two-component system, sensor histidine kinase LadS
C BOP93_02870 hybrid sensor histidine kinase/response regulator K20972 retS; two-component system, sensor histidine kinase RetS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023