+F Repair protein KO
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DNA Repair and Recombination Proteins - Polaribacter sp. MED152
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MED152_07670 ogt; methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MED152_05350 DNA photolyase/cryptochrome, animal cryptochrome and (6-4) photolyase subfamily K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D MED152_05405 phrB; deoxyribodipyrimidine photo-lyase, class I K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MED152_00800 ung; uracil DNA glycosylase superfamily protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MED152_09640 HhH-GPD superfamily base excision DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MED152_01800 nth; HhH-GPD superfamily base excision DNA repair protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D MED152_00515 S1/P1 nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MED152_08725 dut; dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MED152_07670 ogt; methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MED152_05350 DNA photolyase/cryptochrome, animal cryptochrome and (6-4) photolyase subfamily K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D MED152_05405 phrB; deoxyribodipyrimidine photo-lyase, class I K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D MED152_05345 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E MED152_00800 ung; uracil DNA glycosylase superfamily protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MED152_09640 HhH-GPD superfamily base excision DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MED152_11989 tag; DNA-3-methyladenine glycosidase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MED152_01800 nth; HhH-GPD superfamily base excision DNA repair protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MED152_10450 xth; exodeoxyribonuclease III (Xth) K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E MED152_07910 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MED152_13454 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MED152_10105 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MED152_04900 uvrA3; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E MED152_01780 uvrA1; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E MED152_03455 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
E MED152_09500 uvrC; excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
E MED152_01615 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MED152_10105 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MED152_13454 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MED152_04810 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MED152_04805 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MED152_12609 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MED152_10740 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MED152_08905 mutS3; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E MED152_00795 mutS1; DNA mismatch repair protein, MutS family K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E MED152_01325 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
E MED152_07245 dnaE1; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MED152_11814 dnaE3; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MED152_04670 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MED152_00675 DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MED152_09190 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MED152_01490 dnaQ1; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MED152_11754 dnaQ5; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MED152_05060 dnaQ3; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MED152_03045 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MED152_13454 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MED152_01615 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MED152_09635 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MED152_09160 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MED152_08735 recA; protein RecA K03553 recA; recombination protein RecA
E MED152_06690 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MED152_10285 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MED152_12029 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MED152_02405 DEAD/DEAH box helicase K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E MED152_08735 recA; protein RecA K03553 recA; recombination protein RecA
E MED152_08245 radA; DNA repair protein RadA/Sms K04485 radA; DNA repair protein RadA/Sms
E MED152_01345 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E MED152_03355 DEAD/DEAH box helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MED152_07910 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MED152_10500 recO; recombination protein O K03584 recO; DNA repair protein RecO (recombination protein O)
E MED152_04560 recR; recombination protein RecR K06187 recR; recombination protein RecR
E MED152_13259 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MED152_06690 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MED152_10285 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MED152_12029 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E MED152_09415 hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E MED152_02560 protein of unknown function (DUF853) K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MED152_04790 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MED152_12139 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MED152_11284 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F MED152_11904 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MED152_09645 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F MED152_00230 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MED152_07910 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MED152_10500 recO; recombination protein O K03584 recO; DNA repair protein RecO (recombination protein O)
F MED152_04560 recR; recombination protein RecR K06187 recR; recombination protein RecR
F MED152_13454 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MED152_02435 DEAD/DEAH box helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MED152_00240 DEAD/DEAH box helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MED152_04900 uvrA3; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F MED152_01780 uvrA1; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F MED152_03455 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MED152_07240 dinP1; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MED152_08645 dinP3; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MED152_06580 peptidase S24-like protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D MED152_08735 recA; protein RecA K03553 recA; recombination protein RecA
D MED152_13259 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MED152_09635 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MED152_09160 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MED152_08540 RecX family protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MED152_10165 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D MED152_08725 dut; dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MED152_06645 ribonucleoside-diphosphate reductase large subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MED152_06650 ribonucleoside-diphosphate reductase small chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MED152_01365 DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024