+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Penicillium oxalicum</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        POX_a01088 mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        POX_a01054 Cyclin-dependent kinase 1	K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22] 
E        POX_h09600 Serine/threonine-protein kinase	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        POX_c04700 mRNA-capping enzyme subunit alpha	K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50] 
D      Cap binding complex
E        POX_c04471 hypothetical protein	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        POX_f08297 Nuclear cap-binding protein subunit 2	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        POX_a00050 Cleavage and polyadenylation specificity factor subunit 5	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        POX_d05247 mRNA cleavage and polyadenylation factor clp1	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        POX_e06392 hypothetical protein	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        POX_c04411 Protein cft1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        POX_b02942 hypothetical protein	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        POX_c03534 Endoribonuclease ysh1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        POX_e07080 mRNA 3'-end-processing protein yth1	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        POX_d04793 Pre-mRNA polyadenylation factor fip1	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        POX_h09565 putative RING finger protein	K15541 MPE1; protein MPE1 
E        POX_f08264 Polyadenylation factor subunit 2	K15542 PFS2; polyadenylation factor subunit 2 
E        POX_d05349 hypothetical protein	K14962 WDR82; COMPASS component SWD2 
E        POX_e06974 Serine/threonine-protein phosphatase PP1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        POX_f08027 Serine/threonine-protein phosphatase PP-Z	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        POX_b02713 Serine/threonine-protein phosphatase PP-Z	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        POX_b02611 RNA polymerase II subunit A C-terminal domain phosphatase ssu72	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        POX_b03063 mRNA 3'-end-processing protein rna14	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        POX_c04357 hypothetical protein	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        POX_b02300 Small nuclear ribonucleoprotein-associated protein B	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        POX_f08079 Small nuclear ribonucleoprotein Sm D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        POX_e06220 Small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        POX_d05154 putative small nuclear ribonucleoprotein F	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        POX_h09845 Small nuclear ribonucleoprotein G	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        POX_b02942 hypothetical protein	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        POX_c03534 Endoribonuclease ysh1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        POX_c04357 hypothetical protein	K06100 SYMPK; symplekin 
D      DRB sensitivity inducing factor (DSIF) complex
E        POX_a00690 Transcription elongation factor spt4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        POX_b02381 Transcription elongation factor spt5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        POX_a00723 RNA N6-adenosine-methyltransferase METTL16	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
D      Poly(A) addition factors
E        POX_c03895 Poly(A) polymerase pla1	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
D      POX_g09244 KIN17-like protein	K13102 KIN; DNA/RNA-binding protein KIN17 
D      POX_f08001 hypothetical protein	K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        POX_b02663 RNA-binding protein 8A	K12876 RBM8A; RNA-binding protein 8A 
E        POX_c04114 Protein mago nashi	K12877 MAGOH; protein mago nashi 
E        POX_a00379 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        POX_d05177 mRNA export protein mlo3	K12881 THOC4; THO complex subunit 4 
E        POX_f07545 ATP-dependent RNA helicase sub2	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        POX_a00090 ATP-dependent RNA helicase FAL1	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        POX_b03127 hypothetical protein	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        POX_c03513 hypothetical protein	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        POX_g08673 hypothetical protein	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        POX_b02208 hypothetical protein	K12878 THOC1; THO complex subunit 1 
E        POX_a00269 hypothetical protein	K12879 THOC2; THO complex subunit 2 
E        POX_a01441 hypothetical protein	K12880 THOC3; THO complex subunit 3 
E        POX_a00379 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        POX_d05177 mRNA export protein mlo3	K12881 THOC4; THO complex subunit 4 
E        POX_b02509 hypothetical protein	K13174 THOC5; THO complex subunit 5 
D      TREX-2 complex
E        POX_a01914 hypothetical protein	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        POX_d05635 putative 26S proteasome complex subunit sem-1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        POX_a00409 hypothetical protein	K23719 SAC3; nuclear mRNA export protein SAC3 
D      Nuclear pore complex
E        POX_a01808 hypothetical protein	K09291 TPR; nucleoprotein TPR 
E        POX_d05962 Nucleoporin GLE2	K14298 RAE1; mRNA export factor 
E        POX_f08127 Nucleoporin GLE2	K14298 RAE1; mRNA export factor 
E        POX_a00922 Protein transport protein sec13	K14004 SEC13; protein transport protein SEC13 
E        POX_c04146 Nucleoporin NUP57	K14308 NUP54; nuclear pore complex protein Nup54 
E        POX_b02654 Nucleoporin NSP1	K14306 NUP62; nuclear pore complex protein Nup62 
E        POX_b02155 Nucleoporin NIC96	K14309 NUP93; nuclear pore complex protein Nup93 
E        POX_a01557 hypothetical protein	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        POX_c04105 hypothetical protein	K14301 NUP107; nuclear pore complex protein Nup107 
E        POX_a00890 hypothetical protein	K14300 NUP133; nuclear pore complex protein Nup133 
E        POX_c03611 hypothetical protein	K14311 NUP188; nuclear pore complex protein Nup188 
E        POX_e06224 Nucleoporin	K14312 NUP155; nuclear pore complex protein Nup155 
E        POX_d05628 hypothetical protein	K14303 NUP160; nuclear pore complex protein Nup160 
E        POX_d04795 hypothetical protein	K14307 NUPL1; nucleoporin p58/p45 
E        POX_f07761 hypothetical protein	K14315 NDC1; nucleoporin NDC1 
E        POX_e07125 hypothetical protein	K14299 SEH1; nucleoporin SEH1 
E        POX_a01137 hypothetical protein	K18715 NUP159; nucleoporin NUP159 
E        POX_g08947 hypothetical protein	K18716 NUP42; nucleoporin NUP42 
E        POX_f08296 Nucleoporin NUP82	K18719 NUP82; nucleoporin NUP82 
E        POX_c04057 hypothetical protein	K18723 GLE1; nucleoporin GLE1 
E        POX_e06993 hypothetical protein	K14284 NXF; nuclear RNA export factor 
E        POX_b02310 hypothetical protein	K14285 NXT1_2; NTF2-related export protein 1/2 
E        POX_a00157 hypothetical protein	K18724 POM34; nucleoporin POM34 
E        POX_g09135 Nucleoporin	K18725 POM152; nucleoporin POM152 
D      Ran-mediated transport factors
E        POX_a01833 GTP-binding nuclear protein GSP1/Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        POX_c03757 hypothetical protein	K18726 FAF2; FAS-associated factor 2 
E        POX_d04988 Cell division control protein 48	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        POX_d05928 Exportin-1	K14290 XPO1; exportin-1 
E        POX_g08975 Ran GTPase-activating protein 1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        POX_a00526 Eukaryotic translation initiation factor	K03259 EIF4E; translation initiation factor 4E 
E        POX_b01985 Eukaryotic translation initiation factor 4E-1	K03259 EIF4E; translation initiation factor 4E 
E        POX_g08679 ATP-dependent RNA helicase eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        POX_f07842 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        POX_d05038 hypothetical protein	K03258 EIF4B; translation initiation factor 4B 
E        POX_g08864 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        POX_f07821 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        POX_a01288 hypothetical protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        POX_e06889 Polyadenylate-binding protein, cytoplasmic and nuclear	K13126 PABPC; polyadenylate-binding protein 
E        POX_f07894 putative ATP-dependent RNA helicase	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        POX_g09320 putative helicase mug81	K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6] 
E        POX_d05713 Translation machinery-associated protein 20	K07575 MCTS; malignant T-cell-amplified sequence 
E        POX_d05910 Translation machinery-associated protein 22	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        POX_f07999 hypothetical protein	K14294 WIBG; partner of Y14 and mago 
E        POX_h09538 putative RNA-binding protein	K14411 MSI; RNA-binding protein Musashi 
E        POX_a00997 HBS1-like protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        POX_b02698 Protein dom34	K06965 PELO; protein pelota 
E        POX_d05763 Polyadenylate-binding protein 2	K14396 PABPN1; polyadenylate-binding protein 2 
E        POX_b03304 ATP-dependent RNA helicase dbp5	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        POX_d05297 Pre-mRNA-splicing factor syf1	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        POX_a01590 hypothetical protein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        POX_b02153 Protein pim1	K11493 RCC1; regulator of chromosome condensation 
E        POX_b02245 THP3	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        POX_e06330 Eukaryotic peptide chain release factor subunit 1	K03265 ETF1; peptide chain release factor subunit 1 
E        POX_a01146 Eukaryotic peptide chain release factor GTP-binding subunit	K03267 ERF3; peptide chain release factor subunit 3 
E        POX_c03607 hypothetical protein	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        POX_a00776 hypothetical protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        POX_d04858 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
D      Protein phosphatase 2A
E        POX_d04801 Serine/threonine-protein phosphatase PP2A catalytic subunit	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        POX_e06793 Protein phosphatase PP2A regulatory subunit A	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        POX_h09774 Protein phosphatase PP2A regulatory subunit B	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        POX_a00107 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        POX_a01288 hypothetical protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        POX_d05376 GTP-binding protein 1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        POX_d05615 hypothetical protein	K14844 PUF6; pumilio homology domain family member 6 
E        POX_a01135 hypothetical protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        POX_b02576 RNA-binding protein rnc1	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        POX_e06343 Myosin-2	K10357 MYO5; myosin V 
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
E        POX_e06638 translation elongation factor EF-1 alpha	K03231 EEF1A; elongation factor 1-alpha 
E        POX_c03501 Glutathione S-transferase-like protein FUS3	K03233 EEF1G; elongation factor 1-gamma 
E        POX_c04686 Elongation factor 1-gamma 2	K03233 EEF1G; elongation factor 1-gamma 
D      Other mRNA localization factors
E        POX_c04060 Virulence protein SSD1	K18748 SSD1; protein SSD1 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        POX_a00532 5'-3' exoribonuclease	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        POX_b03064 hypothetical protein	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        POX_a00526 Eukaryotic translation initiation factor	K03259 EIF4E; translation initiation factor 4E 
E        POX_b01985 Eukaryotic translation initiation factor 4E-1	K03259 EIF4E; translation initiation factor 4E 
E        POX_c03607 hypothetical protein	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        POX_g08864 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        POX_f07821 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        POX_g09142 ATP-dependent RNA helicase dhh1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        POX_c04093 hypothetical protein	K18749 LSM14; protein LSM14 
E        POX_c03958 hypothetical protein	K18752 TNPO1; transportin-1 
E        POX_e07239 cAMP-dependent protein kinase type 2	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        POX_a00183 cAMP-dependent protein kinase catalytic subunit 3	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        POX_d05717 hypothetical protein	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        POX_d05354 hypothetical protein	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        POX_e07194 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        POX_h09878 Sm-like protein LSM2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        POX_d05375 putative U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        POX_e07220 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        POX_c04287 putative U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        POX_e06508 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        POX_c03753 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        POX_c03802 Sm-like protein LSM1B	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        POX_e06343 Myosin-2	K10357 MYO5; myosin V 
E        POX_b03346 Tubulin alpha-1 chain	K07374 TUBA; tubulin alpha 
E        POX_b03212 hypothetical protein	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        POX_e07111 hypothetical protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        POX_g08931 hypothetical protein	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        POX_a01162 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        POX_a01347 Glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        POX_a00302 CCR4-NOT transcription complex subunit 8	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        POX_a00998 PAN2-PAN3 deadenylation complex catalytic subunit pan2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        POX_c03756 PAN2-PAN3 deadenylation complex subunit PAN3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        POX_d05497 hypothetical protein	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
E        POX_a00776 hypothetical protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        POX_d04858 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
E        POX_h09804 DNA-directed RNA polymerase II subunit rpb7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
D      Stress granule specific factors
E        POX_c04178 Oligouridylate-binding protein 1	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        POX_e06889 Polyadenylate-binding protein, cytoplasmic and nuclear	K13126 PABPC; polyadenylate-binding protein 
E        POX_a00841 hypothetical protein	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        POX_g09078 Eukaryotic translation initiation factor 2A	K15026 EIF2A; translation initiation factor 2A 
E        POX_b03401 Eukaryotic translation initiation factor 3 subunit B	K03253 EIF3B; translation initiation factor 3 subunit B 
E        POX_g08679 ATP-dependent RNA helicase eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        POX_a00090 ATP-dependent RNA helicase FAL1	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        POX_d05038 hypothetical protein	K03258 EIF4B; translation initiation factor 4B 
E        POX_f07842 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        POX_a01639 Guanine nucleotide-binding protein subunit beta-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        POX_e06993 hypothetical protein	K14284 NXF; nuclear RNA export factor 
E        POX_a00048 Histone deacetylase clr3	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        POX_d05354 hypothetical protein	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        POX_g09142 ATP-dependent RNA helicase dhh1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        POX_d05497 hypothetical protein	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
D      Lsm complex
E        POX_e07194 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        POX_h09878 Sm-like protein LSM2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        POX_d05375 putative U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        POX_e07220 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        POX_c04287 putative U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        POX_e06508 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        POX_c03753 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        POX_c03802 Sm-like protein LSM1B	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        POX_a00532 5'-3' exoribonuclease	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        POX_c03692 5'-3' exoribonuclease 2	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        POX_d05855 hypothetical protein	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        POX_d05477 hypothetical protein	K07573 CSL4; exosome complex component CSL4 
E        POX_b02531 hypothetical protein	K03681 RRP40; exosome complex component RRP40 
E        POX_b02613 hypothetical protein	K11600 RRP41; exosome complex component RRP41 
E        POX_b03293 hypothetical protein	K12590 RRP46; exosome complex component RRP46 
E        POX_d05076 Exosome complex component MTR3	K12587 MTR3; exosome complex component MTR3 
E        POX_a01270 hypothetical protein	K12589 RRP42; exosome complex component RRP42 
E        POX_f07496 hypothetical protein	K12586 RRP43; exosome complex component RRP43 
E        POX_f08460 Exosome complex component rrp45	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        POX_a01446 Exosome complex exonuclease dis3	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        POX_b02923 hypothetical protein	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        POX_g09049 hypothetical protein	K12592 C1D; exosome complex protein LRP1 
D      TRAMP complex
E        POX_c04301 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        POX_a01652 hypothetical protein	K12597 AIR1_2; protein AIR1/2 
E        POX_f07771 ATP-dependent RNA helicase mtr4	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        POX_f07894 putative ATP-dependent RNA helicase	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        POX_g08770 hypothetical protein	K12600 SKI3; superkiller protein 3 
E        POX_d05942 Meiotic recombination protein rec14	K12601 SKI8; superkiller protein 8 
D      Ccr4-NOT complex
E        POX_a01347 Glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        POX_b03212 hypothetical protein	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        POX_e07111 hypothetical protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        POX_g08931 hypothetical protein	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        POX_a01162 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        POX_a00302 CCR4-NOT transcription complex subunit 8	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        POX_a01467 Cell differentiation protein rcd1	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        POX_c04480 ABC transporter domain-containing protein	K12608 CAF16; CCR4-NOT complex subunit CAF16 
E        POX_e06991 hypothetical protein	K12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120 
D      Pan complex
E        POX_a00998 PAN2-PAN3 deadenylation complex catalytic subunit pan2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        POX_c03756 PAN2-PAN3 deadenylation complex subunit PAN3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        POX_d05855 hypothetical protein	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        POX_a01843 hypothetical protein	K26109 NRDE2; nuclear exosome regulator NRDE2 
E        POX_e06980 Protein vts1	K27407 VTS1; RNA-binding protein VTS1 
C    Other degradation factors
D      RNases
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        POX_a00419 hypothetical protein	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        POX_a00880 hypothetical protein	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        POX_b03110 Oligoribonuclease	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        POX_e06583 Enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        POX_c04778 Enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        POX_g09357 ATP-dependent 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        POX_f07891 Heat shock 70 kDa protein	K04043 dnaK; molecular chaperone DnaK 
E        POX_f08405 Heat shock protein 60	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        POX_d05477 hypothetical protein	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        POX_b02613 hypothetical protein	K11600 RRP41; exosome complex component RRP41 
E        POX_a01270 hypothetical protein	K12589 RRP42; exosome complex component RRP42 
D      Others
!
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#Last updated: April 25, 2024