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Transfer RNA Biogenesis - Komagataella phaffii
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D PAS_chr1-4_0517 Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D PAS_chr1-4_0176 hypothetical protein K14522 POP3; ribonuclease P/MRP protein subunit POP3 [EC:3.1.26.5]
D PAS_chr4_0690 hypothetical protein K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D PAS_chr3_0927 Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursor K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D PAS_chr2-1_0295 Subunit of both RNase MRP K14526 POP7; ribonuclease P/MRP protein subunit POP7 [EC:3.1.26.5]
D PAS_chr4_0566 Subunit of both RNase MRP and nuclear RNase P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D PAS_chr3_1050 hypothetical protein K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
D PAS_chr2-1_0185 Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitoch K14533 RPM2; ribonuclease P protein component, mitochondrial [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D PAS_chr3_0969 tRNase Z, involved in RNA processing K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D PAS_chr2-1_0204 RNAse K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D PAS_chr2-1_0176 ATP (CTP):tRNA-specific tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
D PAS_chr2-2_0157 Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p K15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]
D PAS_chr2-2_0460 hypothetical protein K15323 TSEN34; tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16]
D PAS_chr1-1_0137 hypothetical protein K15325 SEN15; tRNA-splicing endonuclease subunit Sen15, fungi type
D PAS_chr2-2_0250 Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p K15326 TSEN54; tRNA-splicing endonuclease subunit Sen54
C tRNA splicing ligase complex
C Other tRNA splicing factors
D PAS_chr4_0312 tRNA 2'-phosphotransferase K10669 TRPT1; 2'-phosphotransferase [EC:2.7.1.160]
D PAS_chr3_0622 tRNA ligase, required for tRNA splicing K14679 TRL1; tRNA ligase [EC:6.5.1.3]
B tRNA transport factors
C tRNA export factors
D PAS_chr2-1_0449 GTP binding protein (mammalian Ranp homolog) K07936 RAN; GTP-binding nuclear protein Ran
D PAS_chr2-1_0617 Nuclear pore protein involved in nuclear export of pre-tRNA K14288 XPOT; exportin-T
D PAS_chr2-2_0243 Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus K14290 XPO1; exportin-1
D PAS_chr4_0654 Karyopherin involved in nuclear import and export K14289 XPO5; exportin-5
D PAS_FragB_0052 Translational elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D PAS_chr1-1_0065 Component of the U2 snRNP K14547 UTP8; U3 small nucleolar RNA-associated protein 8
D PAS_chr4_0200 Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway K08876 SCYL1; SCY1-like protein 1
C tRNA import factors
D PAS_chr2-1_0137 Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus expo K15436 TRPO3; transportin-3
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D PAS_chr1-1_0241 Mitochondrial glutamyl-tRNA synthetase, encoded by a nuclear gene K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D PAS_chr1-4_0598 Glutamyl-tRNA synthetase, cytoplasmic K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D PAS_chr2-2_0209 Protein with similarity to tRNA synthetases K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D PAS_chr1-1_0391 hypothetical protein K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D PAS_chr2-1_0123 Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D PAS_chr4_0709 isoleucine-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D PAS_chr4_0393 Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PAS_chr1-4_0534 Mitochondrial leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PAS_chr2-1_0396 Mitochondrial methionyl-tRNA synthetase (MetRS) K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D PAS_chr2-1_0346 Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D PAS_chr3_0285 Glutamine tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D PAS_chr3_0166 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D PAS_chr3_0949 Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D PAS_chr1-1_0047 Mitochondrial lysine-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D PAS_chr1-4_0095 Cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D PAS_chr4_0101 Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D PAS_chr2-1_0731 Protein that binds tRNA and methionyl-and glutamyl-tRNA synthetases (Mes1p and Gus1p) K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
D PAS_chr2-1_0314 Protein that binds tRNA and methionyl-and glutamyl-tRNA synthetases (Mes1p and Gus1p) K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
C Other AARSs
D PAS_chr3_0462 Cytoplasmic alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D PAS_chr1-1_0390 Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D PAS_chr1-1_0392 Mitochondrial asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D PAS_chr3_0376 Cytoplasmic and mitochondrial glycyl-tRNA synthase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D PAS_chr2-1_0673 Mitochondrial threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PAS_chr2-2_0238 Threonyl-tRNA synthetase, essential cytoplasmic protein K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PAS_chr1-4_0463 Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D PAS_chr1-4_0104 Probable mitochondrial seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D PAS_chr1-4_0514 hypothetical protein K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D PAS_chr3_0754 Mitochondrial and cytoplasmic valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D PAS_chr1-3_0244 Cytoplasmic and mitochondrial histidine tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D PAS_chr1-4_0558 Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D PAS_chr4_0276 Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D PAS_chr3_0144 Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate ac K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D PAS_chr4_0522 Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D PAS_chr3_1110 Mitochondrial tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D PAS_chr3_0165 Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D PAS_chr2-2_0245 Mitochondrial tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D PAS_chr1-4_0399 D-Tyr-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D PAS_chr1-3_0204 hypothetical protein K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
B tRNA modification factors
C Deaminases
D PAS_chr2-1_0170 tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala K15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
D PAS_chr2-1_0388 Subunit of tRNA-specific adenosine-34 deaminase K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
D PAS_chr2-1_0374 Subunit of tRNA-specific adenosine-34 deaminase K15442 TAD3; tRNA-specific adenosine deaminase 3
C Dihydorouridine synthases
D PAS_FragB_0019 tRNA-dihydrouridine synthase 1 K05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]
D PAS_chr1-4_0247 Dihydrouridine synthase, member of a family of dihydrouridine synthases K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D PAS_chr4_0178 Dihydrouridine synthase K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
D PAS_chr4_0179 Dihydrouridine synthase K05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]
C Methylthiotransferase
C Methyltransferases
D PAS_chr2-1_0090 tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D PAS_chr3_0593 tRNA methyltransferase K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D PAS_chr4_0445 S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase K15334 NCL1; multisite-specific tRNA:(cytosine-C5)-methyltransferase [EC:2.1.1.202]
D PAS_chr3_0632 tRNA(m(1)G37)methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D PAS_chr3_0443 Subunit of tRNA (1-methyladenosine) methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D PAS_chr3_1122 Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D PAS_chr3_0947 2'-O-ribose methyltransferase, methylates the 2'-O-ribose of nucleotides K14864 FTSJ1; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]
D PAS_chr3_1100 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D PAS_chr2-1_0406 tRNA methyltransferase, catalyzes esterification of modified uridine nucleotides in tRNAs K15444 TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]
D PAS_chr1-1_0230 tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D PAS_chr1-4_0354 Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p) K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D PAS_chr2-1_0523 2'-O-methyltransferase responsible for modification of tRNA at position 4 K15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]
D PAS_chr3_0213 tRNA(Ser) Um(44) 2'-O-methyltransferase K15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]
D PAS_chr1-1_0467 hypothetical protein K15443 TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
D PAS_chr1-4_0374 Subunit of an adoMet-dependent tRNA methyltransferase (MTase) complex (Trm11p-Trm112p) K15448 TRM112; multifunctional methyltransferase subunit TRM112
D PAS_chr4_0460 Nonessential protein that binds actin filaments and localizes to actin patches and cables K17053 ABP140; tRNAThr (cytosine32-N3)-methyltransferase [EC:2.1.1.268]
D PAS_chr2-2_0212 S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D PAS_chr1-4_0655 tRNA wybutosine-synthesizing protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D PAS_chr1-4_0457 tRNA methyltransferase required for the synthesis of wybutosine K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
C Psudouridine synthases
D PAS_chr1-4_0212 tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D PAS_chr1-3_0271 Non-essential tRNA:pseudouridine synthase K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D PAS_chr2-1_0067 Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D PAS_chr2-1_0777 Mitochondrial tRNA pseudouridine synthase involved in pseudouridylation of mitochondrial tRNAs K15453 PUS6; tRNA pseudouridine31 synthase [EC:5.4.99.42]
D PAS_chr3_1088 Pseudouridine synthase K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D PAS_chr1-3_0239 DRAP deaminase, catalyzes the third step of the riboflavin biosynthesis pathway K14655 RIB2; tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [EC:5.4.99.28]
C Thiolation factors
D PAS_chr1-4_0029 tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNA K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D PAS_chr3_0775 Protein required for thiolation of the uridine at the wobble position of Gln, Lys, and Glu tRNAs K14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]
D PAS_chr2-2_0373 Protein with a role in urmylation and in invasive and pseudohyphal growth K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D PAS_chr3_0037 Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D PAS_chr2-1_0393 Ubiquitin-like protein with weak sequence similarity to ubiquitin K12161 URM1; ubiquitin related modifier 1
D PAS_chr2-1_0563 Protein that activates Urm1p before its conjugation to proteins (urmylation) K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D PAS_chr2-1_0347 Protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D PAS_chr2-1_0167 Putative metalloprotease, similar to O-sialoglycoprotein metallopeptidase from P. haemolytica K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D PAS_chr2-1_0085 Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex wit K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D PAS_c121_0011 hypothetical protein K15901 TPRKB; EKC/KEOPS complex subunit TPRKB/CGI121
D PAS_chr4_0249 Proposed transcription factor K15902 LAGE3; EKC/KEOPS complex subunit LAGE3/PCC1
D PAS_chr2-2_0121 Protein proposed to be involved in the modification of N-linked oligosaccharides K15903 GON7; EKC/KEOPS complex subunit GON7
C Elongator complex
D PAS_chr2-2_0263 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA K11373 ELP1; elongator complex protein 1
D PAS_chr4_0778 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA K11374 ELP2; elongator complex protein 2
D PAS_chr4_0098 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D PAS_chr2-1_0284 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA K11375 ELP4; elongator complex protein 4
D PAS_chr4_0558 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA K11376 ELP5; elongator complex protein 5
D PAS_chr2-1_0281 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA K11377 ELP6; elongator complex protein 6
C Elongator related proteins
D PAS_chr1-1_0438 Zn-ribbon protein K15455 DPH3; diphthamide biosynthesis protein 3
D PAS_chr1-4_0637 Protein kti12 K15456 KTI12; protein KTI12
D PAS_chr1-1_0239 Protein required, with Elongator complex, Kti11p & Kti12p, for modification of wobble nucleosides in K15462 KTI13; protein ATS1
D PAS_chr2-1_0219 Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, an K14758 HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]
D PAS_chr3_0217 Type 2A-related serine-threonine phosphatase K15427 SIT4; serine/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]
D PAS_chr4_0541 Protein that forms a complex with the Sit4p protein phosphatase and is required for its function K15458 SAP185_190; SIT4-associating protein SAP185/190
D PAS_chr1-3_0135 Protein that forms a complex with the Sit4p protein phosphatase K15458 SAP185_190; SIT4-associating protein SAP185/190
C Other tRNA modification factors
D PAS_chr1-4_0326 Protein required for respiratory growth K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D PAS_chr1-3_0185 Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D PAS_chr1-4_0563 Mitochondrial protein, forms a heterodimer complex with Mto1p K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D PAS_chr3_0908 Mitochondrial protein, forms a heterodimer complex with Mss1p K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D PAS_chr2-1_0283 Putative tRNA acetyltransferase K06963 TAN1; tRNA acetyltransferase TAN1
D PAS_chr1-4_0323 tRNAHis guanylyltransferase K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D PAS_chr4_0401 Arginyl-tRNA-protein transferase K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
B tRNA degradation factors
C TRAMP complex
D PAS_chr4_0229 Catalytic subunit of TRAMP (Trf4/Pap2p-Mtr4p-Air1p/2p) K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D PAS_chr2-2_0239 RING finger protein that interacts with the arginine methyltransferase Hmt1p K12597 AIR1_2; protein AIR1/2
C Rapid tRNA decay (RTD) pathway factors
D PAS_chr3_0432 Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D PAS_chr3_0846 Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D PAS_chr2-1_0547 Bisphosphate-3'-nucleotidase, involved in salt tolerance and methionine biogenesis K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D PAS_chr3_0969 tRNase Z, involved in RNA processing K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D PAS_chr2-1_0204 RNAse K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D PAS_chr2-1_0176 ATP (CTP):tRNA-specific tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D PAS_chr4_0393 Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PAS_chr1-4_0534 Mitochondrial leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D PAS_chr2-2_0209 Protein with similarity to tRNA synthetases K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D PAS_chr1-1_0391 hypothetical protein K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D PAS_chr4_0522 Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D PAS_chr3_1110 Mitochondrial tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D PAS_chr3_0165 Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D PAS_chr2-2_0245 Mitochondrial tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D PAS_chr2-1_0673 Mitochondrial threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PAS_chr2-2_0238 Threonyl-tRNA synthetase, essential cytoplasmic protein K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D PAS_chr2-1_0123 Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D PAS_chr4_0709 isoleucine-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D PAS_chr3_0949 Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D PAS_chr1-1_0047 Mitochondrial lysine-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D PAS_chr3_0462 Cytoplasmic alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D PAS_chr3_0754 Mitochondrial and cytoplasmic valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D PAS_chr2-1_0396 Mitochondrial methionyl-tRNA synthetase (MetRS) K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D PAS_chr2-1_0346 Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D PAS_chr1-4_0463 Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D PAS_chr1-4_0104 Probable mitochondrial seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D PAS_chr4_0101 Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D PAS_chr1-4_0514 hypothetical protein K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D PAS_chr1-1_0241 Mitochondrial glutamyl-tRNA synthetase, encoded by a nuclear gene K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D PAS_chr1-4_0598 Glutamyl-tRNA synthetase, cytoplasmic K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D PAS_chr3_0285 Glutamine tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D PAS_chr3_0166 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D PAS_chr1-4_0558 Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D PAS_chr4_0276 Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D PAS_chr3_0144 Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate ac K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D PAS_chr1-3_0244 Cytoplasmic and mitochondrial histidine tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D PAS_chr1-1_0390 Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D PAS_chr1-1_0392 Mitochondrial asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D PAS_chr1-4_0399 D-Tyr-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D PAS_chr1-3_0204 hypothetical protein K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D PAS_chr3_1100 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D PAS_chr1-4_0563 Mitochondrial protein, forms a heterodimer complex with Mto1p K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
C Psudouridine synthases
D PAS_chr1-4_0212 tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D PAS_chr2-1_0067 Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D PAS_chr3_1088 Pseudouridine synthase K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D PAS_chr3_0037 Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D PAS_chr2-1_0347 Protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D PAS_chr2-1_0167 Putative metalloprotease, similar to O-sialoglycoprotein metallopeptidase from P. haemolytica K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D PAS_chr2-1_0085 Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex wit K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D PAS_chr3_0908 Mitochondrial protein, forms a heterodimer complex with Mss1p K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D PAS_chr1-3_0185 Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D PAS_chr4_0708 hypothetical protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D PAS_chr1-4_0326 Protein required for respiratory growth K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D PAS_chr2-2_0277 Protein of unknown function, localized to the mitochondrial outer membrane K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024