+D Protein KO
#
Membrane Trafficking - Komagataella phaffii
%
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AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
D PAS_chr4_0548 Component of the septin ring of the mother-bud neck that is required for cytokinesis K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D PAS_chr1-4_0069 Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D PAS_chr4_0700 Phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D PAS_chr3_0646 Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D PAS_chr1-1_0457 Phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PAS_c131_0004 hypothetical protein K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
D PAS_chr1-1_0057 Putative protein serine/threonine kinase expressed at the end of meiosis K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D PAS_chr2-2_0059 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D PAS_chr3_0347 Serine/threonine protein kinase involved in regulation of exocytosis K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D PAS_chr1-1_0170 N-myristoylated calcium-binding protein that may have a role in intracellular signaling K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D PAS_chr3_0143 Secretory vesicle-associated Rab GTPase essential for exocytosis K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D PAS_chr2-1_0758 Calmodulin K02183 CALM; calmodulin
D PAS_chr2-2_0435 hypothetical protein K02183 CALM; calmodulin
D PAS_chr2-2_0014 Guanyl-nucleotide exchange factor for the small G-protein Sec4p K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D PAS_chr4_0134 Sm-like protein involved in docking and fusion of exocytic vesicles K15292 STXBP1; syntaxin-binding protein 1
D PAS_chr1-4_0066 Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p K08518 STXBP5; syntaxin-binding protein 5
D PAS_FragB_0076 hypothetical protein K19952 RABIF; guanine nucleotide exchange factor
D PAS_chr2-1_0074 GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its acti K19953 GRTP1; TBC1 domain family member 6
D PAS_chr3_0801 Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p K19951 TBC1D8_9; TBC1 domain family member 8/9
D PAS_chr2-2_0186 Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1) K13342 PEX5; peroxin-5
D PAS_chr3_0586 Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p K23460 CHM; Rab proteins geranylgeranyltransferase component A
D PAS_chr4_0741 Alpha subunit of Type II geranylgeranyltransferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PAS_chr3_0764 Beta subunit of Type II geranylgeranyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PAS_chr2-1_0345 Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym K24155 DMXL; rabconnectin-3a
C Rho GTPases
D PAS_chr2-1_0112 Small rho-like GTPase, essential for establishment and maintenance of cell polarity K04393 CDC42; cell division control protein 42
D PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D PAS_chr1-4_0550 hypothetical protein K19983 EXOC1; exocyst complex component 1
D PAS_chr3_1229 hypothetical protein K17637 EXOC2; exocyst complex component 2
D PAS_chr1-4_0452 Essential 88kDa subunit of the exocyst complex K06110 EXOC3; exocyst complex component 3
D PAS_chr2-1_0039 Essential 121kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p K06111 EXOC4; exocyst complex component 4
D PAS_chr1-4_0334 Essential 100kDa subunit of the exocyst complex K19984 EXOC5; exocyst complex component 5
D PAS_chr2-1_0297 Essential 113kDa subunit of the exocyst complex K19985 EXOC6; exocyst complex component 6
D PAS_chr4_0695 Essential 70kDa subunit of the exocyst complex K07195 EXOC7; exocyst complex component 7
D PAS_chr4_0078 Essential protein with dual roles in spliceosome assembly and exocytosis K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D PAS_chr4_0299 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
D PAS_chr4_0115 Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D PAS_chr4_0675 Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p K19877 CHS5; chitin biosynthesis protein CHS5
D PAS_chr4_0542 Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p) K19880 CHS6; Chs5-Arf1p-binding protein CHS6/BCH2
D PAS_chr2-1_0141 Member of the ChAPs family (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms th K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D PAS_chr3_0529 hypothetical protein K19992 MSO1; protein MSO1
D PAS_chr2-1_0830 hypothetical protein K12481 RBSN; rabenosyn-5
D PAS_chr2-2_0077 Putative phosphatidylinositol transfer protein (PITP) K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D PAS_chr1-4_0294 Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
D PAS_chr2-2_0350 Target membrane receptor (t-SNARE) K21155 VAM3; syntaxin VAM3
C Stx-TGN / EE
D PAS_chr3_1238 hypothetical protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D PAS_chr1-4_0024 cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
D PAS_chr3_0989 t-SNARE required for ER membrane fusion and vesicular traffic K08492 STX18; syntaxin 18
B SNAP-25[N] (Qb)
C Vti1
D PAS_chr3_1085 Protein involved in cis-Golgi membrane traffic K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D PAS_chr2-1_0161 v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28 K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D PAS_chr2-2_0453 hypothetical protein K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
D PAS_chr1-4_0462 Membrane glycoprotein V-SNARE K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
D PAS_chr3_0048 Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived K08499 TLG1; member of the syntaxin family of t-SNAREs
C STX8
D PAS_chr1-1_0246 hypothetical protein K08501 STX8; syntaxin 8
D PAS_chr1-4_0500 hypothetical protein K08502 VAM7; regulator of vacuolar morphogenesis
C STX10
C Bet1
D PAS_chr1-3_0161 Type II membrane protein required for vesicular transport K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
D PAS_chr1-1_0481 hypothetical protein K08507 USE1; unconventional SNARE in the endoplasmic reticulum protein 1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D PAS_chr2-2_0132 t-SNARE protein important for fusion of secretory vesicles with the plasma membrane K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D PAS_FragB_0011 Synaptobrevin homolog 2 K08513 VAMP4; vesicle-associated membrane protein 4
D PAS_chr2-1_0099 hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D PAS_FragB_0006 Synaptobrevin homolog YKT6 K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D PAS_chr3_0274 R-SNARE protein K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D PAS_chr1-4_0066 Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D PAS_chr4_0134 Sm-like protein involved in docking and fusion of exocytic vesicles K15292 STXBP1; syntaxin-binding protein 1
D PAS_chr4_0251 Hydrophilic protein, involved in vesicle trafficking between the ER and Golgi K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D PAS_chr1-4_0126 Palmitoyltransferase for Vac8p, required for vacuolar membrane fusion K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PAS_chr2-1_0056 Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D PAS_chr2-1_0829 hypothetical protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D PAS_chr3_0342 ATPase required for the release of Sec17p K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D PAS_chr2-1_0644 Peripheral membrane protein required for vesicular transport between ER and Golgi K15296 NAPA; alpha-soluble NSF attachment protein
D PAS_chr2-1_0389 Sorting nexin K17919 SNX4; sorting nexin-4
D PAS_chr2-2_0030 Sorting nexin family member K21996 SNX41_42; sorting nexin-41/42
D PAS_chr3_1139 Sorting nexin K21996 SNX41_42; sorting nexin-41/42
D PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases K15620 GOLPH3; golgi phosphoprotein 3
D PAS_FragD_0026 ATPase in ER, nuclear membrane and cytosol with homology to mammalian P97 K13525 VCP; transitional endoplasmic reticulum ATPase
D PAS_chr2-1_0159 UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and K14012 NSFL1C; UBX domain-containing protein 1
D PAS_FragB_0007 Protein VTS1 K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D PAS_chr1-4_0546 Clathrin heavy chain, subunit of the major coat protein K04646 CLTC; clathrin heavy chain
C Dynamin
D PAS_chr3_0751 Dynamin-related GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D PAS_chr2-1_0496 Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2) K11824 AP2A; AP-2 complex subunit alpha
D PAS_chr3_0079 Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2) K11825 AP2B1; AP-2 complex subunit beta-1
D PAS_chr2-2_0175 Mu2-like subunit of the clathrin associated protein complex (AP-2) K11826 AP2M1; AP-2 complex subunit mu-1
D PAS_chr3_1047 Small subunit of the clathrin-associated adaptor complex AP-2 K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D PAS_chr3_0865 Protein with a potential role in actin cytoskeletal organization K20042 FCHO; F-BAR domain only protein
D PAS_chr1-4_0244 Epsin-like protein involved in endocytosis and actin patch assembly K12471 EPN; epsin
D PAS_FragB_0073 hypothetical protein K12471 EPN; epsin
D PAS_chr4_0763 Protein containing an N-terminal epsin-like domain K12471 EPN; epsin
D PAS_chr2-1_0651 Key endocytic protein involved in a network of interactions with other endocytic proteins K12472 EPS15; epidermal growth factor receptor substrate 15
D PAS_chr2-2_0405 Protein involved in clathrin cage assembly K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D PAS_chr2-1_0116 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) K12562 AMPH; amphiphysin
D PAS_chr3_0498 Actin-associated protein K12562 AMPH; amphiphysin
D PAS_chr3_0983 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) K12562 AMPH; amphiphysin
D PAS_chr2-1_0366 Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D PAS_chr3_0694 Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D PAS_chr4_0920 hypothetical protein K20048 END3; actin cytoskeleton-regulatory complex protein END3
D PAS_chr3_0731 Cytoplasmic ATPase that is a ribosome-associated molecular chaperone K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PAS_chr4_0552 ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PAS_chr3_0230 ATPase involved in protein folding and the response to stress K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D PAS_chr1-1_0457 Phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D PAS_chr2-1_0255 Protein of unknown function involved in maintenance of proper telomere length K20059 LDB19; arrestin-related trafficking adapter 1
D PAS_chr1-3_0216 hypothetical protein K20060 ECM21; arrestin-related trafficking adapter 2/8
D PAS_chr4_0694 Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D PAS_chr3_0930 Membrane protein K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D PAS_chr3_1017 Putative protein of unknown function K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D PAS_chr4_0184 hypothetical protein K20063 RIM8; arrestin-related trafficking adapter 9
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D PAS_chr2-1_0178 Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols K20279 SYNJ; synaptojanin [EC:3.1.3.36]
D PAS_chr2-1_0424 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sa K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D PAS_chr2-1_0460 Protein serine/threonine kinase K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D PAS_chr2-1_0028 Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D PAS_chr2-1_0354 Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D PAS_chr4_0879 Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization K20040 HIP1R; huntingtin-interacting protein 1-related protein
D PAS_chr2-1_0322 Calnexin K08054 CANX; calnexin
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D PAS_chr3_0751 Dynamin-related GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D PAS_chr2-1_0124 Elongation factor 2 (EF-2), also encoded by EFT1 K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D PAS_chr2-1_0112 Small rho-like GTPase, essential for establishment and maintenance of cell polarity K04393 CDC42; cell division control protein 42
D PAS_chr2-2_0087 ADP-ribosylation factor, GTPase of the Ras superfamily K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D PAS_chr4_0214 Glucose-repressible ADP-ribosylation factor K07941 ARF6; ADP-ribosylation factor 6
D PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D PAS_chr3_0150 GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell pol K04513 RHOA; Ras homolog gene family, member A
D PAS_chr3_0751 Dynamin-related GTPase K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D PAS_chr4_0618 One of two type I myosins K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D PAS_chr4_0680 GTP-binding protein K07827 KRAS; GTPase KRas
D PAS_chr3_0133 GTP-binding protein of the ras superfamily required for bud site selection K07827 KRAS; GTPase KRas
D PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D PAS_chr2-1_0112 Small rho-like GTPase, essential for establishment and maintenance of cell polarity K04393 CDC42; cell division control protein 42
C Kinases
D PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PAS_c131_0004 hypothetical protein K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C Phospholipase C
D PAS_chr4_0700 Phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D PAS_chr3_0990 Nexin-1 homolog required for localizing membrane proteins K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D PAS_chr2-1_0116 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) K12562 AMPH; amphiphysin
D PAS_chr3_0498 Actin-associated protein K12562 AMPH; amphiphysin
D PAS_chr3_0983 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) K12562 AMPH; amphiphysin
D PAS_chr1-4_0384 Amphiphysin-like lipid raft protein K20120 BIN3; bridging integrator 3
D PAS_chr3_0833 Amphiphysin-like lipid raft protein K20120 BIN3; bridging integrator 3
C F-BAR proteins
D PAS_chr4_0215 SH3 domain protein implicated in the regulation of actin polymerization K20121 FNBP1; formin-binding protein 1
D PAS_chr3_0865 Protein with a potential role in actin cytoskeletal organization K20042 FCHO; F-BAR domain only protein
D PAS_chr4_0681 GTPase-activating protein (RhoGAP) for Rho3p and Rho4p K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D PAS_chr1-4_0162 GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5 K07889 RAB5C; Ras-related protein Rab-5C
D PAS_chr4_0219 GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D PAS_chr3_0203 Guanine nucleotide exchange factor K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D PAS_chr2-1_0830 hypothetical protein K12481 RBSN; rabenosyn-5
D PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PAS_chr3_0042 Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D PAS_chr1-1_0150 Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D PAS_chr2-2_0087 ADP-ribosylation factor, GTPase of the Ras superfamily K07937 ARF1_2; ADP-ribosylation factor 1/2
D PAS_chr4_0214 Glucose-repressible ADP-ribosylation factor K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D PAS_chr1-4_0340 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector K12486 SMAP; stromal membrane-associated protein
D PAS_chr3_1109 Protein that localizes to the nucleus and is involved in transcription regulation K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D PAS_chr1-3_0100 Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PAS_chr1-3_0180 hypothetical protein K21842 EFR3; protein EFR3
D PAS_chr3_0536 hypothetical protein K21845 YPP1; cargo-transport protein YPP1
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D PAS_chr1-4_0162 GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5 K07889 RAB5C; Ras-related protein Rab-5C
D PAS_chr4_0219 GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases K07889 RAB5C; Ras-related protein Rab-5C
D PAS_chr4_0899 GTP-binding protein K07897 RAB7A; Ras-related protein Rab-7A
D PAS_chr2-1_0669 GTPase K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D PAS_chr1-4_0503 Endosomal subunit of membrane-associated retromer complex required for retrograde transport K18468 VPS35; vacuolar protein sorting-associated protein 35
D PAS_chr3_1146 hypothetical protein K18467 VPS29; vacuolar protein sorting-associated protein 29
D PAS_chr4_0074 Vacuolar protein sorting protein K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
C Rab associated proteins
D PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PAS_chr3_0450 Alpha 4 subunit of the 20S proteasome K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D PAS_c121_0003 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D PAS_chr1-3_0254 GTPase-activating protein for yeast Rab family members K20168 TBC1D15; TBC1 domain family member 15
D PAS_chr3_0586 Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p K23460 CHM; Rab proteins geranylgeranyltransferase component A
D PAS_chr4_0741 Alpha subunit of Type II geranylgeranyltransferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PAS_chr3_0764 Beta subunit of Type II geranylgeranyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
D PAS_chr2-1_0527 hypothetical protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D PAS_chr3_0234 Catalytic subunit of N-terminal acetyltransferase of the NatC type K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D PAS_chr1-1_0190 Non-catalytic subunit of N-terminal acetyltransferase of the NatC type K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D PAS_chr3_0780 hypothetical protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D PAS_FragB_0049 Vacuolar protein sorting-associated protein 27 K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D PAS_c131_0007 hypothetical protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D PAS_chr3_0136 Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into K12183 TSG101; ESCRT-I complex subunit TSG101
D PAS_chr2-1_0182 Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, and Mvb12p), which is involved in ubiquitin K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D PAS_chr3_1165 hypothetical protein K12188 SNF8; ESCRT-II complex subunit VPS22
D PAS_chr4_0993 hypothetical protein K12189 VPS25; ESCRT-II complex subunit VPS25
D PAS_chr3_0312 Component of the ESCRT-II complex K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D PAS_chr1-4_0657 Vacuolar protein sorting protein K12197 CHMP1; charged multivesicular body protein 1
D PAS_c131_0013 hypothetical protein K12191 CHMP2A; charged multivesicular body protein 2A
D PAS_chr1-1_0034 vacuolar sorting protein K12193 VPS24; charged multivesicular body protein 3
D PAS_chr1-4_0023 One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III) K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D PAS_chr3_0168 Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport K12198 CHMP5; charged multivesicular body protein 5
D PAS_chr4_0420 Myristoylated subunit of ESCRTIII K12195 CHMP6; charged multivesicular body protein 6
D PAS_chr1-3_0288 hypothetical protein K15053 CHMP7; charged multivesicular body protein 7
D PAS_chr2-1_0572 AAA-type ATPase that is regulated by Vta1p K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D PAS_chr4_0635 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D PAS_chr1-3_0184 Protein involved in proteolytic activation of Rim101p in response to alkaline pH K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D PAS_chr3_1175 hypothetical protein K20177 VPS3; vacuolar protein sorting-associated protein 3
D PAS_chr1-4_0606 Membrane-associated protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D PAS_chr1-3_0306 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D PAS_chr3_0210 Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex K20180 VPS16; vacuolar protein sorting-associated protein 16
D PAS_chr2-1_0574 Component of CORVET tethering complex K20181 VPS18; vacuolar protein sorting-associated protein 18
D PAS_chr2-2_0264 ATP-binding protein that is A subunit of the HOPS complex and the CORVET tethering complex K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D PAS_chr1-3_0306 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D PAS_chr3_0210 Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex K20180 VPS16; vacuolar protein sorting-associated protein 16
D PAS_chr2-1_0574 Component of CORVET tethering complex K20181 VPS18; vacuolar protein sorting-associated protein 18
D PAS_chr2-2_0264 ATP-binding protein that is A subunit of the HOPS complex and the CORVET tethering complex K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D PAS_chr1-1_0460 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D PAS_chr4_0062 Vacuolar membrane protein K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D PAS_chr2-1_0345 Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym K24155 DMXL; rabconnectin-3a
C RAVE complex
D PAS_chr2-1_0345 Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym K24155 DMXL; rabconnectin-3a
D PAS_chr3_0390 Subunit of RAVE (Rav1p, Rav2p, Skp1p) K25485 RAV2; regulator of V-ATPase in vacuolar membrane protein 2
D PAS_chr3_1258 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D PAS_FragB_0027 AP-3 complex subunit delta K12396 AP3D; AP-3 complex subunit delta
D PAS_chr2-2_0415 Beta3-like subunit of the yeast AP-3 complex K12397 AP3B; AP-3 complex subunit beta
D PAS_chr2-1_0788 Mu3-like subunit of the clathrin associated protein complex (AP-3) K12398 AP3M; AP-3 complex subunit mu
D PAS_chr3_0122 Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
D PAS_chr4_0296 hypothetical protein K22240 CNL1; biogenesis of lysosome-related organelles complex 1 subunit CNL1
D PAS_chr4_0611 hypothetical protein K22241 SNN1; biogenesis of lysosome-related organelles complex 1 subunit SNN1
D PAS_FragB_0026 hypothetical protein K22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D PAS_chr3_1107 Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole K20195 MON1; vacuolar fusion protein MON1
D PAS_chr4_0614 hypothetical protein K21156 CCZ1; vacuolar fusion protein CCZ1, fungi type
D PAS_chr1-3_0261 Ubiquitin isopeptidase K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PAS_chr2-2_0056 hypothetical protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D PAS_chr1-4_0644 Dynamin-like GTPase required for vacuolar sorting K23481 VPS1; vacuolar protein sorting-associated protein 1
D PAS_chr3_0606 PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins K24781 BPH1; beige protein homolog 1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D PAS_chr1-4_0528 GTPase of the Ypt/Rab family, very similar to Ypt31p K07905 RAB11B; Ras-related protein Rab-11B
C Rab4 associated proteins
D PAS_chr2-1_0830 hypothetical protein K12481 RBSN; rabenosyn-5
D PAS_chr2-1_0389 Sorting nexin K17919 SNX4; sorting nexin-4
C Rab11 associated proteins
D PAS_chr1-1_0471 hypothetical protein K20241 WDR44; WD repeat-containing protein 44
D PAS_chr1-3_0057 Component of both the Nup84 nuclear pore sub-complex and of the COPII complex K14004 SEC13; protein transport protein SEC13
D PAS_chr2-1_0297 Essential 113kDa subunit of the exocyst complex K19985 EXOC6; exocyst complex component 6
D PAS_FragB_0038 GTPase-activating protein K20242 EVI5; ecotropic viral integration site 5 protein
D PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D PAS_chr3_0203 Guanine nucleotide exchange factor K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D PAS_chr3_0904 Strand exchange protein, forms a helical filament with DNA that searches for homology K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D PAS_chr1-3_0031 Golgi-associated retrograde protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D PAS_chr3_0301 Component of the GARP (Golgi-associated retrograde protein) complex K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D PAS_c131_0006 hypothetical protein K10364 CAPZA; F-actin-capping protein subunit alpha
D PAS_chr3_0548 Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D PAS_chr3_1146 hypothetical protein K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D PAS_chr4_0165 GTPase, Ras-like GTP binding protein involved in the secretory pathway K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases K15620 GOLPH3; golgi phosphoprotein 3
D PAS_chr3_0801 Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p K19951 TBC1D8_9; TBC1 domain family member 8/9
D PAS_chr2-1_0682 hypothetical protein K20286 TMF1; TATA element modulatory factor
D PAS_chr4_0389 Large subunit of the dynactin complex K04648 DCTN1; dynactin 1
D PAS_chr1-1_0211 Putative vacuolar protein sorting-associated protein vps13 K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D PAS_chr2-2_0087 ADP-ribosylation factor, GTPase of the Ras superfamily K07937 ARF1_2; ADP-ribosylation factor 1/2
D PAS_chr2-2_0316 Soluble GTPase with a role in regulation of membrane traffic K07942 ARL1; ADP-ribosylation factor-like protein 1
D PAS_chr2-2_0078 GTPase of the Ras superfamily required to recruit Arl1p to the Golgi K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D PAS_chr3_0974 ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D PAS_chr3_0559 ADP-ribosylation factor GTPase activating protein (ARF GAP) K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D PAS_chr1-4_0340 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector K12486 SMAP; stromal membrane-associated protein
D PAS_chr3_1109 Protein that localizes to the nucleus and is involved in transcription regulation K12486 SMAP; stromal membrane-associated protein
D PAS_chr1-4_0667 hypothetical protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D PAS_chr1-4_0432 Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D PAS_chr3_0206 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D PAS_chr4_0916 hypothetical protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D PAS_chr1-1_0250 Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p) K20291 COG4; conserved oligomeric Golgi complex subunit 4
D PAS_chr4_0073 Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p) K20293 COG6; conserved oligomeric Golgi complex subunit 6
D PAS_chr2-2_0228 hypothetical protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D PAS_chr4_0693 hypothetical protein K20297 VPS51; vacuolar protein sorting-associated protein 51
D PAS_chr1-3_0031 Golgi-associated retrograde protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D PAS_chr3_0301 Component of the GARP (Golgi-associated retrograde protein) complex K20299 VPS53; vacuolar protein sorting-associated protein 53
D PAS_chr1-1_0314 Component of the GARP (Golgi-associated retrograde protein) complex K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D PAS_chr2-2_0224 Component of the TRAPP (transport protein particle) complex K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PAS_chr2-1_0476 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PAS_chr1-3_0080 Hydrophilic protein that acts in conjunction with SNARE proteins K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PAS_chr2-2_0180 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PAS_chr1-3_0091 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PAS_chr3_1098 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi K20304 TRAPPC6; trafficking protein particle complex subunit 6
D PAS_chr2-1_0774 Subunit of TRAPP (transport protein particle) K20305 TRAPPC8; trafficking protein particle complex subunit 8
D PAS_chr2-1_0811 hypothetical protein K20306 TRAPPC9; trafficking protein particle complex subunit 9
D PAS_chr2-1_0532 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi K20307 TRAPPC10; trafficking protein particle complex subunit 10
D PAS_chr2-2_0374 hypothetical protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D PAS_chr4_0721 hypothetical protein K20311 TRS65; trafficking protein particle complex II-specific subunit 65
D PAS_chr4_0371 hypothetical protein K20312 TCA17; TRAPP-associated protein TCA17
B Others
C AP-1 complex
D PAS_chr2-1_0537 Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex K12391 AP1G1; AP-1 complex subunit gamma-1
D PAS_chr1-4_0010 Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex K12392 AP1B1; AP-1 complex subunit beta-1
D PAS_chr4_0852 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1) K12393 AP1M; AP-1 complex subunit mu
D PAS_chr1-4_0112 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1) K12393 AP1M; AP-1 complex subunit mu
D PAS_chr1-3_0140 Small subunit of the clathrin-associated adaptor complex AP-1 K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D PAS_FragB_0027 AP-3 complex subunit delta K12396 AP3D; AP-3 complex subunit delta
D PAS_chr2-2_0415 Beta3-like subunit of the yeast AP-3 complex K12397 AP3B; AP-3 complex subunit beta
D PAS_chr2-1_0788 Mu3-like subunit of the clathrin associated protein complex (AP-3) K12398 AP3M; AP-3 complex subunit mu
D PAS_chr3_0122 Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
D PAS_chr4_0297 Golgi-localized protein with homology to gamma-adaptin K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D PAS_chr2-2_0037 AP-1 accessory protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D PAS_chr3_0646 Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D PAS_chr1-3_0100 Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PAS_chr1-1_0457 Phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PAS_chr3_1215 hypothetical protein K20318 SYS1; protein SYS1
D PAS_chr2-2_0062 Putative protein of unknown function K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D PAS_chr1-1_0423 hypothetical protein K23542 TMEM199; TMEM199 family protein
D PAS_chr1-1_0493 hypothetical protein K23543 CCDC115; coiled-coil domain-containing protein 115
D PAS_chr2-1_0793 Vacuolar membrane protein of unknown function that is conserved in mammals K23544 SERINC1; serine incorporator 1
D PAS_chr3_0639 Sorting nexin K17918 SNX3_12; sorting nexin-3/12
D PAS_chr3_0269 Protein required for sorting proteins to the vacuole K17922 SNX8; sorting nexin-8
D PAS_chr2-1_0066 Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p A K26678 MON2; protein MON2
D PAS_chr2-1_0180 Protein of unknown function, essential for viability K26680 DOP1; protein dopey
D PAS_chr2-1_0104 hypothetical protein K26750 TVP15; golgi apparatus membrane protein TVP15
D PAS_chr2-1_0239 Integral membrane protein localized to late Golgi vesicles along with the V-SNARE Tlg2p K26751 TVP18; golgi apparatus membrane protein TVP18
D PAS_chr2-2_0091 Integral membrane protein localized to late Golgi vesicles along with the V-SNARE Tlg2p K26752 TVP23; golgi apparatus membrane protein TVP23
D PAS_chr4_0758 Integral membrane protein localized to late Golgi vesicles along with the V-SNARE Tlg2p K26753 TVP38; golgi apparatus membrane protein TVP38
D PAS_chr1-4_0644 Dynamin-like GTPase required for vacuolar sorting K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D PAS_chr1-1_0180 GTPase; GTP-binding protein of the ARF family, component of COPII coat of vesicles K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D PAS_chr1-3_0057 Component of both the Nup84 nuclear pore sub-complex and of the COPII complex K14004 SEC13; protein transport protein SEC13
D PAS_chr1-4_0231 Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles K14005 SEC31; protein transport protein SEC31
D PAS_chr1-1_0048 GTPase-activating protein K14006 SEC23; protein transport protein SEC23
D PAS_chr4_0600 GTPase-activating protein K14006 SEC23; protein transport protein SEC23
D PAS_chr4_0484 Member of the Sec24p family K14007 SEC24; protein transport protein SEC24
D PAS_chr3_0614 Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat K14007 SEC24; protein transport protein SEC24
D PAS_chr4_0606 Guanine nucleotide exchange factor (GEF) K14003 PREB; prolactin regulatory element-binding protein
C TRAPP complex I
D PAS_chr2-2_0224 Component of the TRAPP (transport protein particle) complex K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PAS_chr2-1_0476 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PAS_chr1-3_0080 Hydrophilic protein that acts in conjunction with SNARE proteins K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PAS_chr2-2_0180 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PAS_chr1-3_0091 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PAS_chr3_1098 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D PAS_chr2-1_0564 Possible U3 snoRNP protein involved in maturation of pre-18S rRNA K20346 TMED4_9_11; p24 family protein alpha
D PAS_chr2-1_0633 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles K20347 TMED2; p24 family protein beta-1
D PAS_chr3_1259 hypothetical protein K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D PAS_chr4_0844 Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D PAS_chr1-1_0160 Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D PAS_chr1-3_0125 Member of the protein disulfide isomerase (PDI) family K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D PAS_chr4_0991 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D PAS_chr3_1167 hypothetical protein K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
D PAS_chr1-4_0120 Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport K20359 RABAC1; PRA1 family protein 1
D PAS_chr2-1_0484 Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport K20359 RABAC1; PRA1 family protein 1
D PAS_chr1-4_0364 Rab GTPase-activating protein K20372 TBC1D20; TBC1 domain family member 20
D PAS_chr1-3_0219 Cis-golgi GTPase-activating protein (GAP) K20360 TBC1D22; TBC1 domain family member 2
D PAS_chr1-3_0082 Integral membrane protein K20362 YIF1; protein transport protein YIF1
D PAS_chr1-3_0062 Integral membrane protein required for ER to Golgi transport K22939 IER3IP1; immediate early response 3-interacting protein 1
D PAS_chr4_0088 Essential protein involved in intracellular protein transport K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D PAS_chr4_0432 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles K10080 LMAN1; lectin, mannose-binding 1
D PAS_chr2-2_0178 hypothetical protein K10082 LMAN2; lectin, mannose-binding 2
D PAS_chr2-1_0753 Alpha-1,2-mannosidase involved in ER quality control K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D PAS_chr3_0875 Protein localized to COPII-coated vesicles, forms a complex with Erv46p K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D PAS_chr2-1_0796 Protein localized to COPII-coated vesicles, forms a complex with Erv41p K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D PAS_chr1-4_0225 ER-derived vesicles protein ERV14 K20368 CNIH; protein cornichon
D PAS_chr2-1_0287 Protein localized to COPII-coated vesicles K20369 ERV29; ER-derived vesicles protein
D PAS_chr2-1_0140 ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding I K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D PAS_chr1-1_0294 Alpha subunit of COPI vesicle coatomer complex K05236 COPA; coatomer subunit alpha
D PAS_chr4_0798 Essential beta-coat protein of the COPI coatomer K17301 COPB1; coatomer subunit beta
D PAS_chr1-1_0181 Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport K17302 COPB2; coatomer subunit beta'
D PAS_chr4_0225 Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat K17267 COPG; coatomer subunit gamma
D PAS_chr1-1_0035 Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles K20471 COPD; coatomer subunit delta
D PAS_chr3_0690 Epsilon-COP subunit of the coatomer K17268 COPE; coatomer subunit epsilon
D PAS_chr1-4_0317 Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D PAS_chr3_1248 hypothetical protein K20474 RINT1; RAD50-interacting protein 1
D PAS_chr1-3_0088 hypothetical protein K11578 ZW10; protein transport protein DSL1/ZW10
D PAS_chr2-1_0440 hypothetical protein K20475 SEC39; protein transport protein SEC39
C Golgi to ER traffic proteins (GET)
D PAS_chr4_0403 hypothetical protein K22384 GET1; tail-anchored protein insertion receptor
D PAS_chr3_0197 hypothetical protein K22386 GET2; GET complex subunit GET2
D PAS_chr4_0405 Guanine nucleotide exchange factor for Gpa1p K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D PAS_chr3_0280 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Rab GTPases
D PAS_chr4_0165 GTPase, Ras-like GTP binding protein involved in the secretory pathway K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D PAS_chr4_0534 hypothetical protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D PAS_chr1-3_0067 Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6 K20477 RGP1; RAB6A-GEF complex partner protein 2
D PAS_chr4_0775 HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins K10949 KDELR; ER lumen protein retaining receptor
D PAS_chr2-1_0830 hypothetical protein K12481 RBSN; rabenosyn-5
D PAS_chr1-3_0219 Cis-golgi GTPase-activating protein (GAP) K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D PAS_chr3_0421 Member of an oxysterol-binding protein family with seven members in S. cerevisiae K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
D PAS_chr1-4_0646 Oxysterol-binding protein K22285 OSBPL8; oxysterol-binding protein-related protein 8
D PAS_chr1-4_0278 Member of the oxysterol binding protein family, which includes seven yeast homologs K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D PAS_chr4_0870 hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D PAS_chr2-1_0397 Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles K20363 YIPF5_7; protein YIPF5/7
D PAS_FragD_0007 hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D PAS_chr2-1_0327 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D PAS_chr4_0765 Putative protein of unknown function K23563 EMC2; ER membrane protein complex subunit 2
D PAS_chr2-1_0551 Putative protein of unknown function K23564 EMC3; ER membrane protein complex subunit 3
D PAS_chr2-1_0296 Putative protein of unknown function K23565 EMC4; ER membrane protein complex subunit 4
D PAS_chr3_0541 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D PAS_chr4_0517 Putative protein of unknown function K23567 EMC6; ER membrane protein complex subunit 6
C SEC61 complex
D PAS_chr1-4_0629 Subunit of the Ssh1 translocon complex K10956 SEC61A; protein transport protein SEC61 subunit alpha
D PAS_chr1-3_0202 Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p) K10956 SEC61A; protein transport protein SEC61 subunit alpha
D PAS_chr2-2_0210 Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) K09481 SEC61B; protein transport protein SEC61 subunit beta
D PAS_chr1-1_0023 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D PAS_chr3_0464 Putative protein of unknown function K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D PAS_chr2-1_0699 GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D PAS_chr2-2_0114 Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity K23553 PGAP3; post-GPI attachment to proteins factor 3
D PAS_chr3_0423 Putative membrane protein of unknown function involved in Mn2+ homeostasis K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
D PAS_chr1-4_0333 hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
D PAS_chr3_0483 Conserved phosphoesterase domain-containing protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D PAS_chr4_0251 Hydrophilic protein, involved in vesicle trafficking between the ER and Golgi K19998 SCFD1; sec1 family domain-containing protein 1
D PAS_chr3_0229 hypothetical protein K20724 TMEM33; transmembrane protein 33
D PAS_chr4_0551 hypothetical protein K20724 TMEM33; transmembrane protein 33
D PAS_chr4_0483 Protein required for normal intracellular sterol distribution and for sphingolipid metabolism K21848 ARV1; lipid intermediate transporter
D PAS_chr1-3_0133 hypothetical protein K21849 KEG1; beta-1,6-glucan synthesis-associated protein KEG1
D PAS_chr4_0508 Protein required for beta-1,6 glucan biosynthesis K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases K15620 GOLPH3; golgi phosphoprotein 3
D PAS_chr2-1_0884 hypothetical protein K23292 LNPK; endoplasmic reticulum junction formation protein lunapark
D PAS_chr1-3_0097 hypothetical protein K26681 INSIG; insulin-induced protein
D PAS_chr1-1_0271 Evolutionarily conserved non-essential protein present in early Golgi cisternae K26683 GOLT1; vesicle transport protein GOT1
D PAS_chr3_0279 Protein of unknown function, contains two predicted GTP-binding motifs K22698 SEY1; protein SEY1 [EC:3.6.5.-]
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AAutophagy
B Autophagosome formation proteins
C ULK complex
D PAS_chr2-2_0432 Regulatory subunit of the Atg1p signaling complex K08331 ATG13; autophagy-related protein 13
D PAS_chr3_0501 hypothetical protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D PAS_chr2-1_0641 Protein serine/threonine kinase required for vesicle formation in autophagy K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D PAS_chr2-2_0432 Regulatory subunit of the Atg1p signaling complex K08331 ATG13; autophagy-related protein 13
D PAS_chr2-1_0672 Scaffold protein responsible for pre-autophagosomal structure organization K08329 ATG17; autophagy-related protein 17
C PI3K complex
D PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PAS_chr3_0042 Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D PAS_chr2-1_0211 Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II K08334 BECN; beclin
C ATG9 transmembrane protein
D PAS_chr4_0510 Transmembrane protein involved in formation of Cvt and autophagic vesicles K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D PAS_chr3_0931 Phosphoinositide binding protein required for vesicle formation in autophagy K17908 WIPI1_2; autophagy-related protein 18
D PAS_chr3_1016 Phosphoinositide binding protein K17908 WIPI1_2; autophagy-related protein 18
D PAS_chr1-3_0168 Peripheral membrane protein required for vesicle formation K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D PAS_chr3_0363 Conserved ubiquitin-like modifier K08336 ATG12; ubiquitin-like protein ATG12
D PAS_chr1-4_0310 Autophagy-related protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D PAS_chr4_0459 Conserved protein involved in autophagy and the Cvt pathway K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D PAS_chr4_0704 Conserved protein that is a component of autophagosomes and Cvt vesicles K08341 GABARAP; GABA(A) receptor-associated protein
D PAS_chr1-4_0522 Conserved cysteine protease required for autophagy K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D PAS_chr1-4_0310 Autophagy-related protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D PAS_chr3_0688 E2-like enzyme involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D PAS_chr3_0803 Vacuolar aminopeptidase K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D PAS_chr4_0790 Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D PAS_chr4_0913 hypothetical protein K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D PAS_chr1-4_0555 Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D PAS_chr2-2_0030 Sorting nexin family member K21996 SNX41_42; sorting nexin-41/42
D PAS_chr3_1139 Sorting nexin K21996 SNX41_42; sorting nexin-41/42
D PAS_chr2-1_0389 Sorting nexin K17919 SNX4; sorting nexin-4
D PAS_chr1-1_0465 hypothetical protein K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D PAS_chr2-2_0110 Type I membrane protein involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway K21141 ATG27; autophagy-related protein 27
D PAS_chr1-4_0101 Phosphorylated vacuolar membrane protein that interacts with Atg13p K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D PAS_chr1-4_0555 Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D PAS_chr2-1_0285 Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenanceof the mitoc K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C Other mitophagy associated proteins
D PAS_chr4_0624 Non-essential protein of unknown function required for transcriptional induction K00844 HK; hexokinase [EC:2.7.1.1]
D PAS_chr1-4_0447 Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol K00844 HK; hexokinase [EC:2.7.1.1]
D PAS_chr3_1192 hypothetical protein K00844 HK; hexokinase [EC:2.7.1.1]
D PAS_chr1-4_0561 Hexokinase-2 K00844 HK; hexokinase [EC:2.7.1.1]
D PAS_chr1-1_0315 Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase K22255 ATPIF1; ATPase inhibitor, mitochondrial
D PAS_chr3_1190 hypothetical protein K17771 TOM7; mitochondrial import receptor subunit TOM7
D PAS_chr1-1_0431 hypothetical protein K19717 ATG33; autophagy-related protein 33
B Pexophagy
C Selective cargos
D PAS_chr3_1073 Peroxisomal membrane protein (PMP) K13336 PEX3; peroxin-3
D PAS_chr4_0794 Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery K13343 PEX14; peroxin-14
C Cargo receptors
D PAS_chr3_1230 ATG30 K22259 ATG30; autophagy-related protein 30
C Other pexophagy associated proteins
D PAS_chr3_1045 Peroxisome biosynthesis protein PAS1 K13338 PEX1; peroxin-1
D PAS_chr1-4_0133 AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D PAS_FragD_0026 ATPase in ER, nuclear membrane and cytosol with homology to mammalian P97 K13525 VCP; transitional endoplasmic reticulum ATPase
D PAS_chr2-1_0302 Putative catalytic subunit of a class II histone deacetylase complex K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D PAS_chr4_0974 hypothetical protein K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D PAS_chr2-1_0437 Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PAS_chr3_0693 Tetrameric phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PAS_chr3_0826 Tetrameric phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PAS_chr2-1_0769 Pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PAS_chr2-1_0892 hypothetical protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D PAS_chr3_0731 Cytoplasmic ATPase that is a ribosome-associated molecular chaperone K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PAS_chr4_0552 ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PAS_chr3_0230 ATPase involved in protein folding and the response to stress K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PAS_chr1-4_0130 Heat shock protein Hsp90 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D PAS_FragB_0052 Translational elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D PAS_chr1-4_0013 carboxypeptidase Y K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D PAS_chr1-4_0101 Phosphorylated vacuolar membrane protein that interacts with Atg13p K08332 VAC8; vacuolar protein 8
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D PAS_chr2-1_0285 Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenanceof the mitoc K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D PAS_chr2-1_0557 PIK-related protein kinase and rapamycin target K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D PAS_chr2-2_0150 Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface K08266 MLST8; target of rapamycin complex subunit LST8
D PAS_chr2-1_0459 Subunit of TORC1, a rapamycin-sensitive complex involved in growth control K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D PAS_chr2-1_0557 PIK-related protein kinase and rapamycin target K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D PAS_chr2-2_0150 Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface K08266 MLST8; target of rapamycin complex subunit LST8
D PAS_chr3_0162 Component of a membrane-bound complex containing the Tor2p kinase and other proteins K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D PAS_chr4_0955 hypothetical protein K08267 RICTOR; rapamycin-insensitive companion of mTOR
D PAS_chr2-1_0241 Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regu K25576 AVO2; target of rapamycin complex 2 subunit AVO2
C SEACIT/GATOR1 complex
D PAS_chr1-3_0181 hypothetical protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D PAS_chr4_0159 Protein with a possible role in regulating expression of nitrogen permeases K20405 NPRL2; nitrogen permease regulator 2
D PAS_chr1-4_0385 Ser/Thr protein kinase involved in salt tolerance K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D PAS_chr1-4_0442 hypothetical protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D PAS_chr1-3_0222 hypothetical protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D PAS_chr1-1_0224 Nuclear pore protein that is part of the evolutionarily conserved Nup84p complex K14299 SEH1; nucleoporin SEH1
D PAS_chr1-3_0057 Component of both the Nup84 nuclear pore sub-complex and of the COPII complex K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D PAS_chr3_1167 hypothetical protein K07874 RAB1A; Ras-related protein Rab-1A
D PAS_chr3_0143 Secretory vesicle-associated Rab GTPase essential for exocytosis K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D PAS_chr1-1_0307 Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D PAS_chr1-4_0119 Essential protein involved in the TOR signaling pathway K17606 IGBP1; immunoglobulin-binding protein 1
D PAS_chr2-1_0083 hypothetical protein K21249 UVRAG; UV radiation resistance-associated gene protein
D PAS_chr1-1_0353 Vacuolar integral membrane protein K06902 UMF1; MFS transporter, UMF1 family
D PAS_chr3_0295 Vacuolar transporter K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D PAS_chr2-2_0343 Vacuolar transporter, exports large neutral amino acids from the vacuole K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D PAS_chr1-4_0196 Phosphatidylinositol 3,5-bisphosphate-binding protein K22991 WDR45; WD repeat-containing protein 45
D PAS_chr1-1_0410 Vacuolar ATPase assembly integral membrane protein VMA21 K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21
D PAS_chr1-4_0625 hypothetical protein K27411 PHAF1; phagosome assembly factor 1
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
D PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D PAS_chr4_0618 One of two type I myosins K10356 MYO1; myosin I
D PAS_FragB_0012 Myosin-2 K10357 MYO5; myosin V
C Arp2/3 complex
D PAS_chr2-2_0328 Subunit of the ARP2/3 complex K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D PAS_chr3_1121 Subunit of the ARP2/3 complex K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D PAS_chr3_0238 Subunit of the ARP2/3 complex K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D PAS_chr1-4_0185 Subunit of the ARP2/3 complex K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D PAS_chr2-2_0029 Subunit of the ARP2/3 complex K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D PAS_chr3_0458 Essential component of the Arp2/3 complex K17260 ACTR2; actin-related protein 2
D PAS_chr2-1_0556 Essential component of the Arp2/3 complex K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D PAS_chr1-4_0623 Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments K23612 WASL; neural Wiskott-Aldrich syndrome protein
D PAS_chr2-2_0320 Actin-binding protein of the cortical actin cytoskeleton K20520 DBNL; drebrin-like protein
D PAS_chr3_0694 Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D PAS_chr2-1_0116 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) K12562 AMPH; amphiphysin
D PAS_chr3_0498 Actin-associated protein K12562 AMPH; amphiphysin
D PAS_chr3_0983 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) K12562 AMPH; amphiphysin
D PAS_chr2-1_0366 Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D PAS_chr3_1226 hypothetical protein K20521 BBC1; myosin tail region-interacting protein MTI1
D PAS_chr4_0500 Protein that induces appearance of [PIN+] prion when overproduced K20522 LSB1_2; LAS seventeen-binding protein 1/2
D PAS_chr3_0795 Protein involved in the organization of the actin cytoskeleton K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D PAS_chr4_0841 hypothetical protein K20524 LSB5; LAS seventeen-binding protein 5
D PAS_chr1-4_0143 Type II phosphatidylinositol 4-kinase that binds Las17p K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D PAS_chr3_0106 Profilin, actin-and phosphatidylinositol 4,5-bisphosphate-binding protein, involved in cytoskeleton K05759 PFN; profilin
D PAS_chr1-4_0027 Cofilin, promotes actin filament depolarization in a pH-dependent manner K05765 CFL; cofilin
D PAS_chr2-2_0067 CAP (cyclase-associated protein) subunit of adenylyl cyclase complex K17261 CAP1_2; adenylyl cyclase-associated protein
D PAS_chr3_0589 Component of yeast cortical actin cytoskeleton K20526 TAGLN; transgelin
B Mucins
C Membrane bound mucins
C Secretory mucins
B Specific organelles associated proteins
C Melanosome
C Auto phagosome
C Lipid droplets
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D PAS_chr4_0681 GTPase-activating protein (RhoGAP) for Rho3p and Rho4p K20643 RGD1; Rho GTPase-activating protein RGD1
C Rho guanine nucleotide exchange factors (GEFs)
D PAS_chr2-1_0599 Protein of unknown function with similarity to human DOCK proteins K05727 DOCK3; dedicator of cytokinesis protein 3
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: September 2, 2024