+D
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Transfer RNA Biogenesis - Proteus penneri
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D I6G31_05350 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D I6G31_06245 ribonuclease K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D I6G31_12545 multifunctional CCA addition/repair protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D I6G31_05335 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D I6G31_15350 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D I6G31_13025 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D I6G31_06400 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D I6G31_04560 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D I6G31_03845 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D I6G31_04415 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D I6G31_00285 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D I6G31_14650 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D I6G31_00325 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D I6G31_04900 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D I6G31_03355 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D I6G31_01920 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D I6G31_03540 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D I6G31_13620 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D I6G31_07690 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D I6G31_15210 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D I6G31_01895 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D I6G31_01890 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D I6G31_01590 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D I6G31_10005 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
C AARS associated factors
D I6G31_02825 hinT; purine nucleoside phosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D I6G31_05140 trmB; tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D I6G31_13030 tsaA; tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D I6G31_15920 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D I6G31_07870 truB; tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D I6G31_13170 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D I6G31_15130 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D I6G31_08555 tsaC; L-threonylcarbamoyladenylate synthase type 1 TsaC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D I6G31_08160 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D I6G31_09640 mnmE; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D I6G31_09890 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D I6G31_17400 selD; selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D I6G31_08055 cysQ; 3'(2'),5'-bisphosphate nucleotidase CysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D I6G31_09625 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D I6G31_06600 rnpB; RNase P RNA component class A K01978 rnpB; RNase P catalytic RNA component
B 3'processing and CCA adding factors
C 3'processing factors
D I6G31_05350 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D I6G31_01625 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D I6G31_09555 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D I6G31_01260 exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D I6G31_00435 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D I6G31_06245 ribonuclease K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D I6G31_12545 multifunctional CCA addition/repair protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D I6G31_05335 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D I6G31_01265 RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D I6G31_06515 ettA; energy-dependent translational throttle protein EttA K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D I6G31_04560 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D I6G31_13025 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D I6G31_01590 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D I6G31_10005 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D I6G31_01920 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D I6G31_06400 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D I6G31_14650 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D I6G31_04900 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D I6G31_07690 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D I6G31_03845 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D I6G31_03540 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D I6G31_00325 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D I6G31_10820 glyQ; glycine--tRNA ligase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D I6G31_10815 glyS; glycine--tRNA ligase subunit beta K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D I6G31_13620 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D I6G31_15350 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D I6G31_04415 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D I6G31_00285 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D I6G31_01895 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D I6G31_01890 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D I6G31_15210 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D I6G31_03355 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D I6G31_05525 gluQRS; tRNA glutamyl-Q(34) synthetase GluQRS K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D I6G31_13525 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D I6G31_03755 YbaK/prolyl-tRNA synthetase associated domain-containing protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D I6G31_15030 tadA; tRNA adenosine(34) deaminase TadA K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D I6G31_11430 dusA; tRNA dihydrouridine(20/20a) synthase DusA K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D I6G31_06945 dusB; tRNA dihydrouridine synthase DusB K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D I6G31_03975 dusC; tRNA dihydrouridine(16) synthase DusC K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D I6G31_04495 miaB; tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D I6G31_00315 cmoA; carboxy-S-adenosyl-L-methionine synthase CmoA K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D I6G31_00310 cmoB; tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D I6G31_03405 cmoM; tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D I6G31_09120 trmA; tRNA (uridine(54)-C5)-methyltransferase TrmA K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D I6G31_05140 trmB; tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D I6G31_04830 trmD; tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D I6G31_09640 mnmE; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D I6G31_04725 tRNA/rRNA methyltransferase K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D I6G31_10780 trmH; tRNA (guanosine(18)-2'-O)-methyltransferase TrmH K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D I6G31_15120 trmJ; tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D I6G31_09380 trmL; tRNA (uridine(34)/cytosine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase TrmL K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D I6G31_13030 tsaA; tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D I6G31_14965 tRNA1(Val) (adenine(37)-N6)-methyltransferase K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D I6G31_15920 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D I6G31_07870 truB; tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D I6G31_12880 truC; tRNA pseudouridine(65) synthase TruC K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D I6G31_13170 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D I6G31_10210 RluA family pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D I6G31_12705 rluA; bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D I6G31_02725 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D I6G31_01475 ttcA; tRNA 2-thiocytidine(32) synthetase TtcA K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D I6G31_07080 tusA; sulfurtransferase TusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D I6G31_11110 tusB; sulfurtransferase complex subunit TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D I6G31_11105 tusC; sulfurtransferase complex subunit TusC K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D I6G31_11100 tusD; sulfurtransferase complex subunit TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D I6G31_03230 tusE; sulfurtransferase TusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D I6G31_15140 iscA; iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D I6G31_15130 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D I6G31_14610 ygfZ; tRNA-modifying protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D I6G31_09890 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D I6G31_08160 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D I6G31_15890 mnmC; bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D I6G31_06140 queA; tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D I6G31_05925 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D I6G31_13115 queD; 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D I6G31_13110 queE; 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D I6G31_12865 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase QueF K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D I6G31_08180 queG; tRNA epoxyqueuosine(34) reductase QueG K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D I6G31_17400 selD; selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D I6G31_01025 mnmH; tRNA 2-selenouridine(34) synthase MnmH K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D I6G31_06135 tgt; tRNA guanosine(34) transglycosylase Tgt K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D I6G31_06040 thiI; tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D I6G31_13010 tilS; tRNA lysidine(34) synthetase TilS K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D I6G31_17070 tRNA(Met) cytidine acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D I6G31_00420 tsaB; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D I6G31_08555 tsaC; L-threonylcarbamoyladenylate synthase type 1 TsaC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D I6G31_12530 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D I6G31_08175 tsaE; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D I6G31_12825 tcdA; tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C I6G31_08120 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C I6G31_07860 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025