+C Two-component system KO
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Two-Component System - Paenibacillus polygoni
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C QPK24_07695 ATP-binding protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C QPK24_07700 response regulator transcription factor K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C QPK24_22215 response regulator transcription factor K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
C QPK24_16415 ATP-binding protein K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
C QPK24_16420 response regulator transcription factor K07775 resD; two-component system, OmpR family, response regulator ResD
B VicK-VicR (cell wall metabolism)
C QPK24_23310 walK; cell wall metabolism sensor histidine kinase WalK K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
C QPK24_23315 yycF; response regulator YycF K07668 vicR; two-component system, OmpR family, response regulator VicR
B MprB-MprA (maintenance of persistent infection)
C QPK24_07335 response regulator transcription factor K07669 mprA; two-component system, OmpR family, response regulator MprA
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
C QPK24_22975 sensor histidine kinase K11629 bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]
C QPK24_22970 response regulator transcription factor K11630 bceR; two-component system, OmpR family, bacitracin resistance response regulator BceR
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
C QPK24_10215 sensor histidine kinase K11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
C QPK24_03805 response regulator transcription factor K18349 vanRC; two-component system, OmpR family, response regulator VanR
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
C QPK24_22760 HAMP domain-containing sensor histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
C QPK24_22765 response regulator transcription factor K18941 arlR; two-component system, OmpR family, response regulator ArlR
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C QPK24_12455 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
C QPK24_21730 sensor histidine kinase K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
C QPK24_21725 response regulator transcription factor K07692 degU; two-component system, NarL family, response regulator DegU
B DesK-DesR (membrane lipid fluidity regulation)
C QPK24_03960 sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
C QPK24_03965 response regulator transcription factor K07693 desR; two-component system, NarL family, response regulator DesR
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
C QPK24_07320 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
C QPK24_20215 sensor histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
C QPK24_07325 response regulator transcription factor K11618 liaR; two-component system, NarL family, response regulator LiaR
C QPK24_20210 response regulator transcription factor K11618 liaR; two-component system, NarL family, response regulator LiaR
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
C QPK24_06140 histidine kinase K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
C QPK24_01705 PAS domain-containing sensor histidine kinase K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
C QPK24_06145 response regulator transcription factor K07696 nreC; two-component system, NarL family, response regulator NreC
C QPK24_01710 response regulator transcription factor K07696 nreC; two-component system, NarL family, response regulator NreC
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C QPK24_15830 PAS domain S-box protein K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
C QPK24_04770 ATP-binding protein K07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]
C QPK24_23075 ATP-binding protein K07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]
C QPK24_00595 response regulator K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C QPK24_16675 spo0A; sporulation transcription factor Spo0A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C QPK24_01270 sensor histidine kinase K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C QPK24_01275 LytTR family DNA-binding domain-containing protein K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C QPK24_09035 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C QPK24_08985 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C QPK24_09030 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
C QPK24_06870 histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_12760 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_12985 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_13300 histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_13975 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_16905 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_18455 histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_20680 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_23130 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_00895 histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_01585 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_01920 sensor histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C QPK24_03525 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_06665 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_06865 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_08420 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_09415 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_12765 AraC family transcriptional regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_12980 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_13295 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_13970 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_16900 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_18450 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_19630 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_19640 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_20675 response regulator transcription factor K07720 yesN; two-component system, response regulator YesN
C QPK24_23135 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_00890 response regulator K07720 yesN; two-component system, response regulator YesN
C QPK24_01580 response regulator transcription factor K07720 yesN; two-component system, response regulator YesN
C QPK24_01915 response regulator K07720 yesN; two-component system, response regulator YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023