+F	Repair protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Pollicipes pollicipes (gooseneck barnacle)</h2>
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A<b>Eukaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      119100397 activating signal cointegrator 1 complex subunit 3-like	K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] 
D      119110391 LOW QUALITY PROTEIN: deoxyribodipyrimidine photo-lyase-like	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        119111270 uracil-DNA glycosylase-like	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        119112234 uracil-DNA glycosylase-like	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        119101900 uncharacterized protein LOC119101900	K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] 
E        119096101 single-strand selective monofunctional uracil DNA glycosylase-like	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        119095600 single-strand selective monofunctional uracil DNA glycosylase-like isoform X1	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        119112321 adenine DNA glycosylase-like	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        119112990 adenine DNA glycosylase-like	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        119089460 uncharacterized protein LOC119089460	K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] 
E        119089695 uncharacterized protein LOC119089695	K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] 
E        119111958 methyl-CpG-binding domain protein 4-like	K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] 
E        119110695 N-glycosylase/DNA lyase-like	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] 
E        119107795 endonuclease 8-like 1 isoform X1	K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] 
E        119108432 endonuclease 8-like 1	K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] 
E        119108434 endonuclease 8-like 1	K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] 
E        119095977 endonuclease III-like protein 1 isoform X1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
E        119100883 exodeoxyribonuclease-like isoform X1	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
E        119111340 DNA-(apurinic or apyrimidinic site) endonuclease 2-like	K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2] 
D      Long Patch-BER factors
E        DNA polymerase delta complex
F          119091662 DNA polymerase delta catalytic subunit-like	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
F          119113857 DNA polymerase delta subunit 2-like	K02328 POLD2; DNA polymerase delta subunit 2 
F          119096739 DNA polymerase delta subunit 3-like	K03504 POLD3; DNA polymerase delta subunit 3 
E        DNA polymerase epsilon complex
F          119093793 DNA polymerase epsilon catalytic subunit A-like	K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] 
F          119112672 DNA polymerase epsilon subunit 2-like	K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 
F          119102771 LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 3-like	K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] 
E        119090952 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        119095517 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        119095536 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        119093124 flap endonuclease 1-like isoform X1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] 
D      Short Patch-BER factors
E        119104500 DNA polymerase beta-like	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
E        119094270 DNA repair protein XRCC1-like	K10803 XRCC1; DNA-repair protein XRCC1 
D      Other BER factors
E        119108549 tyrosyl-DNA phosphodiesterase 1-like	K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] 
E        119098215 bifunctional polynucleotide phosphatase/kinase-like	K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
E        119102136 bifunctional polynucleotide phosphatase/kinase-like	K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
E        119107488 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        119092080 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        119094182 poly [ADP-ribose] polymerase 1-like	K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
E        119105757 poly [ADP-ribose] polymerase 2-like	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
E        119105858 poly [ADP-ribose] polymerase 2-like	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        XPC-HR23B-CETN2 complex
F          119097881 DNA repair protein complementing XP-C cells homolog	K10838 XPC; xeroderma pigmentosum group C-complementing protein 
F          119098649 UV excision repair protein RAD23 homolog B-like	K10839 RAD23; UV excision repair protein RAD23 
F          119099299 UV excision repair protein RAD23 homolog B-like	K10839 RAD23; UV excision repair protein RAD23 
F          119099311 LOW QUALITY PROTEIN: UV excision repair protein RAD23 homolog B-like	K10839 RAD23; UV excision repair protein RAD23 
E        Cul4-DDB2 complex
F          119105838 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119105852 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119099374 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119099407 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119109698 cullin-4A-like	K10609 CUL4; cullin 4 
F          119109699 cullin-4A-like	K10609 CUL4; cullin 4 
F          119108127 DNA damage-binding protein 1-like	K10610 DDB1; DNA damage-binding protein 1 
E        NER4 complex
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase II complex
F          119103099 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          119094897 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          119103866 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          119111529 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB2-like	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          119111855 DNA-directed RNA polymerase II subunit RPB2	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          119111916 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB2-like	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          119098054 DNA-directed RNA polymerase II subunit RPB3-like	K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 
F          119089555 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit Rpb4-like	K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 
F          119108664 DNA-directed RNA polymerases I, II, and III subunit RPABC1-like	K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 
F          119108714 DNA-directed RNA polymerases I, II, and III subunit RPABC2-like	K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 
F          119106066 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          119107694 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          119093426 DNA-directed RNA polymerase II subunit RPB9-like	K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 
F          119104876 DNA-directed RNA polymerase II subunit RPB11-like	K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 
E        Cul4-CSA complex
F          119105838 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119105852 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119099374 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119099407 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          119109698 cullin-4A-like	K10609 CUL4; cullin 4 
F          119109699 cullin-4A-like	K10609 CUL4; cullin 4 
F          119108127 DNA damage-binding protein 1-like	K10610 DDB1; DNA damage-binding protein 1 
F          119091829 DNA excision repair protein ERCC-8-like	K10570 ERCC8; DNA excision repair protein ERCC-8 
E        Other TCR factor
F          119095694 DNA excision repair protein ERCC-6-like	K10841 ERCC6; DNA excision repair protein ERCC-6 
F          119092620 transcription elongation factor 1 homolog	K25829 ELOF1; transcription elongation factor 1 
D      TFIIH complex
E        119096821 general transcription and DNA repair factor IIH helicase subunit XPB-like	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] 
E        119093181 LOW QUALITY PROTEIN: general transcription and DNA repair factor IIH helicase subunit XPD-like	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        119093685 general transcription and DNA repair factor IIH helicase subunit XPD-like	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        119091942 general transcription factor IIH subunit 1-like	K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 
E        119098808 general transcription factor IIH subunit 2-like isoform X1	K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 
E        119109196 general transcription factor IIH subunit 3-like	K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 
E        119110418 cyclin-dependent kinase 7-like isoform X1	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        119110419 cyclin-dependent kinase 7-like	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        119105891 cyclin-H-like isoform X1	K06634 CCNH; cyclin H 
E        119106478 cyclin-H-like isoform X1	K06634 CCNH; cyclin H 
E        119102572 CDK-activating kinase assembly factor MAT1-like	K10842 MNAT1; CDK-activating kinase assembly factor MAT1 
D      RPA (replication factor A)
E        119096584 replication protein A 32 kDa subunit-A-like	K10739 RFA2; replication factor A2 
E        119096875 replication protein A 32 kDa subunit-B-like	K10739 RFA2; replication factor A2 
D      Other NER factors
E        119093983 DNA repair protein complementing XP-A cells homolog	K10847 XPA; DNA-repair protein complementing XP-A cells 
E        119093743 DNA excision repair protein ERCC-1-like isoform X1	K10849 ERCC1; DNA excision repair protein ERCC-1 
E        119112498 DNA repair endonuclease XPF-like	K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] 
E        119112738 DNA repair endonuclease XPF-like	K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] 
E        119097390 DNA repair protein complementing XP-G cells homolog	K10846 ERCC5; DNA excision repair protein ERCC-5 
E        119100517 MMS19 nucleotide excision repair protein homolog	K15075 MET18; DNA repair/transcription protein MET18/MMS19 
E        119100519 MMS19 nucleotide excision repair protein homolog	K15075 MET18; DNA repair/transcription protein MET18/MMS19 
E        119112307 cullin-3-like	K03869 CUL3; cullin 3 
E        119113999 cullin-5-like	K10612 CUL5; cullin 5 
E        119114253 cullin-5-like	K10612 CUL5; cullin 5 
E        119110513 elongin-C-like	K03872 ELOC; elongin-C 
E        119104548 elongin-B-like isoform X1	K03873 ELOB; elongin-B 
E        119104551 elongin-B-like	K03873 ELOB; elongin-B 
E        119104786 elongin-B-like	K03873 ELOB; elongin-B 
E        119104882 elongin-B-like isoform X1	K03873 ELOB; elongin-B 
E        119095234 transcription elongation factor B polypeptide 3-like	K15076 ELOA; elongin-A 
E        119095237 transcription elongation factor B polypeptide 3-like	K15076 ELOA; elongin-A 
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
E        119100826 LOW QUALITY PROTEIN: DNA mismatch repair protein Msh2-like	K08735 MSH2; DNA mismatch repair protein MSH2 
E        119091368 DNA mismatch repair protein Msh6-like isoform X1	K08737 MSH6; DNA mismatch repair protein MSH6 
D      MutL homologs
E        119096533 DNA mismatch repair protein Mlh1-like	K08734 MLH1; DNA mismatch repair protein MLH1 
E        119103033 mismatch repair endonuclease PMS2-like	K10858 PMS2; DNA mismatch repair protein PMS2 
D      DNA polymerase delta complex
E        119091662 DNA polymerase delta catalytic subunit-like	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
E        119113857 DNA polymerase delta subunit 2-like	K02328 POLD2; DNA polymerase delta subunit 2 
E        119096739 DNA polymerase delta subunit 3-like	K03504 POLD3; DNA polymerase delta subunit 3 
D      RPA (replication factor A)
E        119096584 replication protein A 32 kDa subunit-A-like	K10739 RFA2; replication factor A2 
E        119096875 replication protein A 32 kDa subunit-B-like	K10739 RFA2; replication factor A2 
D      RFC (replication factor C)
E        119100764 replication factor C subunit 1-like	K10754 RFC1; replication factor C subunit 1 
E        119114216 replication factor C subunit 4-like isoform X1	K10755 RFC2_4; replication factor C subunit 2/4 
E        119114219 replication factor C subunit 4-like	K10755 RFC2_4; replication factor C subunit 2/4 
E        119112046 replication factor C subunit 2-like	K10755 RFC2_4; replication factor C subunit 2/4 
E        119110392 LOW QUALITY PROTEIN: replication factor C subunit 5-like	K10756 RFC3_5; replication factor C subunit 3/5 
E        119113025 replication factor C subunit 3-like	K10756 RFC3_5; replication factor C subunit 3/5 
D      Other MMR factors
E        119090952 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        119095517 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        119095536 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        119108442 exonuclease 1-like	K10746 EXO1; exonuclease 1 [EC:3.1.-.-] 
E        119107488 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        119092080 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        119089639 WD repeat-containing protein 76-like	K24755 WDR76; WD repeat-containing protein 76 
E        119090395 WD repeat-containing protein 76-like	K24755 WDR76; WD repeat-containing protein 76 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      MRN(MRX) complex
E        119092381 LOW QUALITY PROTEIN: double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        119092384 double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        119097523 LOW QUALITY PROTEIN: DNA repair protein RAD50-like	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA1-core complex
D      BRCA1-A complex
E        119109356 uncharacterized protein LOC119109356	K12173 BRE; BRCA1-A complex subunit BRE 
E        119094503 lys-63-specific deubiquitinase BRCC36-like	K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] 
D      BRCA1-B complex
E        119111632 LOW QUALITY PROTEIN: Fanconi anemia group J protein homolog	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
E        119111602 DNA topoisomerase 2-binding protein 1-like	K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 
D      BRCA1-C complex
E        119092381 LOW QUALITY PROTEIN: double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        119092384 double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        119097523 LOW QUALITY PROTEIN: DNA repair protein RAD50-like	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA complex
E        119104765 DNA repair protein RAD51 homolog A	K04482 RAD51; DNA repair protein RAD51 
D      RecA family proteins
E        119104765 DNA repair protein RAD51 homolog A	K04482 RAD51; DNA repair protein RAD51 
E        119112883 DNA repair protein RAD51 homolog 4-like isoform X1	K10871 RAD51L3; RAD51-like protein 3 
E        119098751 DNA repair protein XRCC3-like	K10880 XRCC3; DNA-repair protein XRCC3 
D      Rad52 family proteins
D      Rad54 family proteins
E        119091666 DNA repair and recombination protein RAD54-like	K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] 
E        119095594 helicase ARIP4-like	K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] 
E        119095604 helicase ARIP4-like	K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] 
E        119106007 DNA repair and recombination protein RAD54B-like	K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] 
D      RecQ family DNA helicases
E        119112441 ATP-dependent DNA helicase Q1-like	K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] 
E        119096985 Werner syndrome ATP-dependent helicase homolog	K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4] 
E        119097388 Werner syndrome ATP-dependent helicase homolog	K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4] 
E        119102419 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        119091824 ATP-dependent DNA helicase Q5-like	K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4] 
D      Bloom's syndrome complex (BTR)
E        119102419 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        119093048 DNA topoisomerase 3-beta-1-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        119093050 LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        119095196 LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        119089302 recQ-mediated genome instability protein 1-like	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      RPA (replication factor A)
E        119096584 replication protein A 32 kDa subunit-A-like	K10739 RFA2; replication factor A2 
E        119096875 replication protein A 32 kDa subunit-B-like	K10739 RFA2; replication factor A2 
D      Protein phosphatase 4
E        119109520 serine/threonine-protein phosphatase 4 catalytic subunit	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        119093294 serine/threonine-protein phosphatase 4 regulatory subunit 3-like	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
E        119098547 serine/threonine-protein phosphatase 4 regulatory subunit 4-like	K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 
E        119098554 serine/threonine-protein phosphatase 4 regulatory subunit 4-like	K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 
D      AP-5 complex
D      SMC5-SMC6 complex
E        119096814 structural maintenance of chromosomes protein 5-like	K22803 SMC5; structural maintenance of chromosomes protein 5 
E        119104001 structural maintenance of chromosomes protein 6-like	K22804 SMC6; structural maintenance of chromosomes protein 6 
E        119113227 non-structural maintenance of chromosomes element 1 homolog	K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] 
E        119111884 non-structural maintenance of chromosomes element 3 homolog isoform X1	K22823 NSMCE3; non-structural maintenance of chromosomes element 3 
E        119112429 non-structural maintenance of chromosomes element 4 homolog A-like	K22825 NSMCE4; non-structural maintenance of chromosomes element 4 
D      Other HR factors
E        119098167 exonuclease 3'-5' domain-containing protein 2-like	K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] 
E        119094502 LOW QUALITY PROTEIN: crossover junction endonuclease MUS81-like	K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] 
E        119099476 structure-specific endonuclease subunit slx1-like	K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] 
E        119099477 structure-specific endonuclease subunit slx1-like	K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] 
E        119100951 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1	K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] 
E        119101142 uncharacterized protein LOC119101142 isoform X1	K23456 CFAP410; cilla- and flagella-associated protein 
E        119098406 tonsoku-like protein	K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 
C    NHEJ (non-homologous end-joining)
D      DNA-PK complex
E        119109867 X-ray repair cross-complementing protein 5-like	K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 
D      MRX complex
E        119092381 LOW QUALITY PROTEIN: double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        119092384 double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        119097523 LOW QUALITY PROTEIN: DNA repair protein RAD50-like	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      DNA Ligase 4 complex
E        119091489 DNA ligase 4-like	K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] 
E        119107773 uncharacterized protein LOC119107773 isoform X1	K10886 XRCC4; DNA-repair protein XRCC4 
E        119113136 non-homologous end-joining factor 1-like	K10980 NHEJ1; non-homologous end-joining factor 1 
D      X-family DNA polymerases
E        119104500 DNA polymerase beta-like	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
D      Other NHEJ factors
E        119102983 protein artemis-like	K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-] 
E        119101778 tyrosyl-DNA phosphodiesterase 2-like isoform X1	K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] 
C    FA (Fanconi anemia) pathway
D      FA core complex
E        119093115 E3 ubiquitin-protein ligase FANCL-like isoform X1	K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] 
D      FA core complex binding factors
E        119110683 centromere protein X-like	K15360 STRA13; centromere protein X 
E        119108272 ubiquitin-conjugating enzyme E2 T-like	K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] 
E        119108273 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 T-like	K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] 
D      Bloom's syndrome complex (BTR)
E        119102419 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        119093048 DNA topoisomerase 3-beta-1-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        119093050 LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        119095196 LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        119089302 recQ-mediated genome instability protein 1-like	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      FANCD2-I complex
E        119098122 Fanconi anemia group D2 protein-like	K10891 FANCD2; fanconi anemia group D2 protein 
D      Downstream FA components
E        119111632 LOW QUALITY PROTEIN: Fanconi anemia group J protein homolog	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
D      Other FA pathway factors
E        119095202 LOW QUALITY PROTEIN: fanconi-associated nuclease 1-like	K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] 
E        119095207 fanconi-associated nuclease 1-like	K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] 
E        119104765 DNA repair protein RAD51 homolog A	K04482 RAD51; DNA repair protein RAD51 
E        119103533 LOW QUALITY PROTEIN: WD repeat-containing protein 48-like	K15361 WDR48; WD repeat-containing protein 48 
C    Other DSBR factors
D      Protein phosphatase 6
E        119099672 serine/threonine-protein phosphatase 6 catalytic subunit-like	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
E        119101154 serine/threonine-protein phosphatase 6 catalytic subunit-like	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
E        119108391 serine/threonine-protein phosphatase 6 regulatory subunit 3-like	K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 
E        119107844 serine/threonine-protein phosphatase 6 regulatory subunit 3-like	K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 
D      Ubiquitin ligases
E        119107428 E3 ubiquitin-protein ligase rnf8-like	K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] 
E        119110628 E3 ubiquitin-protein ligase rnf8-A-like	K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] 
E        119112673 uncharacterized protein LOC119112673	K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] 
E        119095348 protein mono-ADP-ribosyltransferase PARP12-like	K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] 
E        119110334 E3 ubiquitin-protein ligase RNF168-like	K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31] 
E        119098390 E3 ubiquitin-protein ligase HERC2-like	K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
E        119098401 E3 ubiquitin-protein ligase HERC2-like	K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
D      Others
E        119107568 gastrulation defective protein 1 homolog	K24752 WDR70; WD repeat-containing protein 70 
E        119107666 WD repeat-containing protein 70-like	K24752 WDR70; WD repeat-containing protein 70 
E        119089639 WD repeat-containing protein 76-like	K24755 WDR76; WD repeat-containing protein 76 
E        119090395 WD repeat-containing protein 76-like	K24755 WDR76; WD repeat-containing protein 76 
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
D      119101358 DNA polymerase eta-like	K03509 POLH; DNA polymerase eta [EC:2.7.7.7] 
D      119101383 DNA polymerase eta-like	K03509 POLH; DNA polymerase eta [EC:2.7.7.7] 
D      119107122 DNA polymerase iota-like	K03510 POLI; DNA polymerase iota [EC:2.7.7.7] 
D      119108299 DNA polymerase kappa-like	K03511 POLK; DNA polymerase kappa [EC:2.7.7.7] 
D      119110397 DNA repair protein REV1-like	K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] 
C    B-family DNA polymerases
D      119100063 LOW QUALITY PROTEIN: uncharacterized protein LOC119100063	K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] 
D      119100064 DNA polymerase zeta catalytic subunit-like	K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] 
D      119100067 DNA polymerase zeta catalytic subunit-like	K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] 
C    A-family DNA polymerase
C    Rad6 epistasis group
D      119096405 ubiquitin-conjugating enzyme E2 A-like	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      119107608 ubiquitin-conjugating enzyme E2-17 kDa	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      119113077 helicase-like transcription factor	K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27] 
D      119105785 ubiquitin-conjugating enzyme E2 variant 2-like	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      119099404 ubiquitin-conjugating enzyme E2 N-like	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      119111971 ubiquitin-conjugating enzyme E2 N	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
C    Other TLS factors
D      119090952 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
D      119095517 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
D      119095536 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
D      119092195 sprT-like domain-containing protein Spartan	K24051 SPRTN; SprT-like domain-contaning protein Spartan 
B  Check point factors
C    Rad9-Hus1-Rad1 complex
D      119112383 LOW QUALITY PROTEIN: cell cycle checkpoint control protein RAD9A-like	K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] 
D      119089515 checkpoint protein HUS1-like isoform X1	K10903 HUS1; HUS1 checkpoint protein 
D      119112233 cell cycle checkpoint protein RAD1-like isoform X1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
D      119112594 cell cycle checkpoint protein RAD1-like isoform X1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    HRAD17(Rad24)-RFC complex
D      119112411 cell cycle checkpoint protein RAD17-like	K06662 HRAD17; cell cycle checkpoint protein 
D      119114216 replication factor C subunit 4-like isoform X1	K10755 RFC2_4; replication factor C subunit 2/4 
D      119114219 replication factor C subunit 4-like	K10755 RFC2_4; replication factor C subunit 2/4 
D      119112046 replication factor C subunit 2-like	K10755 RFC2_4; replication factor C subunit 2/4 
D      119110392 LOW QUALITY PROTEIN: replication factor C subunit 5-like	K10756 RFC3_5; replication factor C subunit 3/5 
D      119113025 replication factor C subunit 3-like	K10756 RFC3_5; replication factor C subunit 3/5 
C    Rad17-Mec3-Ddc1 complex
D      119112233 cell cycle checkpoint protein RAD1-like isoform X1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
D      119112594 cell cycle checkpoint protein RAD1-like isoform X1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    FPC (fork protection complex)
D      119111131 protein timeless homolog	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      119111135 uncharacterized protein LOC119111135	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      119103052 TIMELESS-interacting protein-like	K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 
D      119103054 TIMELESS-interacting protein-like	K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 
C    Triple T complex
C    BAG6-UBL4A-GET4 complex
D      119109840 large proline-rich protein bag6-A-like	K23390 BAG6; large proline-rich protein BAG6 
D      119100004 ubiquitin-like protein 4A	K23388 UBL4; ubiquitin-like protein 4 
D      119101029 ubiquitin-like protein 4A	K23388 UBL4; ubiquitin-like protein 4 
D      119101640 ubiquitin-like protein 4A	K23388 UBL4; ubiquitin-like protein 4 
D      119095950 Golgi to ER traffic protein 4 homolog	K23387 GET4; golgi to ER traffic protein 4 
C    Other check point factors
D      119090245 serine-protein kinase ATM-like	K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] 
D      119094268 serine/threonine-protein kinase grp-like	K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] 
D      119112173 serine/threonine-protein kinase Chk2-like	K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
D      119113122 serine/threonine-protein kinase Chk2-like	K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
D      119114855 M-phase inducer phosphatase-like	K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] 
D      119101015 14-3-3 protein zeta-like isoform X1	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      119095432 14-3-3 protein zeta	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      119108600 protein sickie-like isoform X1	K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] 
D      119107628 wee1-like protein kinase 2	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      119108117 LOW QUALITY PROTEIN: wee1-like protein kinase	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      119091276 LOW QUALITY PROTEIN: plastin-1-like	K17336 PLS3; plastin-3 
D      119091546 serine/threonine-protein kinase PLK1-like	K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21] 
D      119097239 serine/threonine-protein kinase Nek4-like	K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] 
D      119100664 protein downstream neighbor of son homolog	K22422 DONSON; protein downstream neighbor of Son 
D      119100668 protein downstream neighbor of son homolog	K22422 DONSON; protein downstream neighbor of Son 
D      119100658 vacuolar protein sorting-associated protein 4-like	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      119093431 vacuolar protein sorting-associated protein 4A-like	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      119093600 vacuolar protein sorting-associated protein 4A-like	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      119098664 LOW QUALITY PROTEIN: abscission/NoCut checkpoint regulator-like	K24778 ZFYVE19; abscission/NoCut checkpoint regulator 
D      119093164 replication stress response regulator SDE2-like	K25059 SDE2; replication stress response regulator SDE2 
B  Other factors with a suspected DNA repair function
C    DNA polymerases
D      119106852 uncharacterized protein LOC119106852	K02331 POL5; DNA polymerase phi [EC:2.7.7.7] 
D      119089373 uncharacterized protein LOC119089373	K02331 POL5; DNA polymerase phi [EC:2.7.7.7] 
D      119111601 DNA-directed primase/polymerase protein-like	K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7] 
C    Nucleases
D      119103873 5' exonuclease Apollo-like isoform X1	K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-] 
C    Helicases
D      119108150 helicase POLQ-like	K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] 
D      119092501 DNA excision repair protein ERCC-6-like 2	K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-] 
C    PSO4 complex
D      119110588 pre-mRNA-processing factor 19-like	K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] 
D      119100841 cell division cycle 5-like protein isoform X1	K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 
D      119099479 pre-mRNA-splicing factor SPF27-like	K12861 BCAS2; pre-mRNA-splicing factor SPF27 
C    Modulation of nucleotide pools
D      119092247 7,8-dihydro-8-oxoguanine triphosphatase-like	K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] 
D      119092697 7,8-dihydro-8-oxoguanine triphosphatase-like	K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] 
D      119101083 8-oxo-dGDP phosphatase NUDT18-like isoform X1	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      119096724 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like isoform X1	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      119091837 LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit-like	K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 
D      119091857 ribonucleoside-diphosphate reductase large subunit-like	K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 
D      119090428 ribonucleoside-diphosphate reductase subunit M2-like	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
#
A<b>Prokaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      119110391 LOW QUALITY PROTEIN: deoxyribodipyrimidine photo-lyase-like	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        119111270 uracil-DNA glycosylase-like	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        119112234 uracil-DNA glycosylase-like	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        119096101 single-strand selective monofunctional uracil DNA glycosylase-like	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        119095600 single-strand selective monofunctional uracil DNA glycosylase-like isoform X1	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        119112321 adenine DNA glycosylase-like	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        119112990 adenine DNA glycosylase-like	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        119095977 endonuclease III-like protein 1 isoform X1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
D      RecJ
D      DNA ligase
D      DNA polymerase I
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase complex (RNAP)
E        TRCF (transcription-repair coupling factor)
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
D      Molecular matchmaker
D      Strand discrimination factor
D      DNA exonucleases
D      DNA polymerase III holoenzyme
D      DNA ligase
D      Other MMR factors
E        119103972 single-stranded DNA-binding protein, mitochondrial-like isoform X1	K03111 ssb; single-strand DNA-binding protein 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      RecBC pathway proteins
D      RecFOR pathway proteins
D      AddAB pathway proteins
D      Other HR factor
D      Archaeal homologous recombinant proteins
C    NHEJ (non-homologous end-joining)
D      Two-component NHEJ DNA repair complex
D      SHIIR (short-homology-independent illegitimate recombination)
E        Facilitator
E        Supressor
D      SHDIR (short-homology-dependent illegitimate recombination)
E        RecET pathway
E        Facilitator
E        Supressor
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
C    Other SOS response factors
D      119103972 single-stranded DNA-binding protein, mitochondrial-like isoform X1	K03111 ssb; single-strand DNA-binding protein 
B  Other factors with a suspected DNA repair function
C    DNA polymerase
C    DNA helicases
C    Modulation of nucleotide pools
D      119096724 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like isoform X1	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
C    Others
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#<hr>
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#Last updated: March 29, 2024