+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Podospora pseudocomata</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        QC762_406740 ABD1; mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        QC762_406070 CDC28; Cyclin-dependent kinase catalytic subunit	K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22] 
E        QC762_205940 KIN28; TFIIH complex serine/threonine-protein kinase subunit kin28	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        QC762_702660 CEG1; Dcp1p-Dcp2p decapping enzyme complex alpha subunit	K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50] 
D      Cap binding complex
E        QC762_210900 cbc1; Nuclear cap-binding protein subunit 1	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        QC762_702520 CBC2; nuclear cap binding complex subunit	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        QC762_707250 hypothetical protein	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        QC762_609880 CLP1; Cleavage polyadenylation factor subunit clp1	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        QC762_306570 PCF11; mRNA 3' end processing factor	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        QC762_102610 CFT1; mRNA cleavage and polyadenylation factor subunit	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        QC762_508800 hypothetical protein	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        QC762_603890 YSH1; endoribonuclease ysh1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        QC762_104090 YTH1; RNA-binding component of cleavage and polyadenylation factor	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        QC762_302360 FIP1; Cleavage polyadenylation factor subunit fip1	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        QC762_210770 MPE1; Protein mpe1	K15541 MPE1; protein MPE1 
E        QC762_709710 PFS2; pre-mRNA cleavage and polyadenylation factor (CPF) complex subunit	K15542 PFS2; polyadenylation factor subunit 2 
E        QC762_711070 hypothetical protein	K14962 WDR82; COMPASS component SWD2 
E        QC762_106920 pzh1; serine/threonine protein phosphatase Pzh1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        QC762_709720 GLC7; type 1 serine/threonine-protein phosphatase catalytic subunit glc7	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        QC762_111640 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        QC762_106970 uncharacterized protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        QC762_508900 RNA14; mRNA 3'-end-processing protein rna14	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        QC762_103640 uncharacterized protein	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        QC762_108350 smb1; Small nuclear ribonucleoprotein-associated protein B	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        QC762_209040 SMD3; small nuclear ribonucleoprotein Sm D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        QC762_122980 SME1; mRNA splicing protein sme1	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        QC762_605050 hypothetical protein	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        QC762_100675 SMG1; Serine/threonine-protein kinase smg1	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        QC762_508800 hypothetical protein	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        QC762_603890 YSH1; endoribonuclease ysh1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        QC762_106970 uncharacterized protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        QC762_103640 uncharacterized protein	K06100 SYMPK; symplekin 
D      DRB sensitivity inducing factor (DSIF) complex
E        QC762_212270 SPT4; transcription elongation factor spt4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        QC762_504110 SPT5; transcription elongation factor spt5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        QC762_302410 hypothetical protein	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
D      Poly(A) addition factors
E        QC762_707490 PAP1; polynucleotide adenylyltransferase	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
D      QC762_209640 uncharacterized protein	K13102 KIN; DNA/RNA-binding protein KIN17 
D      QC762_108000 uncharacterized protein	K27103 SRRT; serrate RNA effector molecule 
D      QC762_109540 uncharacterized protein	K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        QC762_101890 uncharacterized protein	K12876 RBM8A; RNA-binding protein 8A 
E        QC762_600960 MNH1; Protein mago nashi	K12877 MAGOH; protein mago nashi 
E        QC762_0057370 YRA1_1; RNA-binding RNA annealing protein	K12881 THOC4; THO complex subunit 4 
E        QC762_110450 uncharacterized protein	K12881 THOC4; THO complex subunit 4 
E        QC762_0017000 SUB2_1; Suppressor of the cold-sensitive snRNP biogenesis mutant brr1-1	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        QC762_206970 FAL1; RNA helicase	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        QC762_408270 hypothetical protein	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        QC762_705890 hypothetical protein	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        QC762_610870 hypothetical protein	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        QC762_0001730 uncharacterized protein	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        QC762_711190 hypothetical protein	K12878 THOC1; THO complex subunit 1 
E        QC762_123280 RLR1; THO2 plays a role in transcriptional elongation	K12879 THOC2; THO complex subunit 2 
E        QC762_113840 uncharacterized protein	K12880 THOC3; THO complex subunit 3 
E        QC762_0057370 YRA1_1; RNA-binding RNA annealing protein	K12881 THOC4; THO complex subunit 4 
E        QC762_110450 uncharacterized protein	K12881 THOC4; THO complex subunit 4 
E        QC762_102980 uncharacterized protein	K13174 THOC5; THO complex subunit 5 
D      TREX-2 complex
E        QC762_601600 hypothetical protein	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        QC762_610600 SEM1; 26S proteasome complex subunit	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        QC762_403130 CDC31; Calcium-binding component of the spindle pole body (SPB) half-bridge	K16466 CETN3; centrin-3 
E        QC762_203170 SAC3; actin cytoskeleton and mitosis protein	K23719 SAC3; nuclear mRNA export protein SAC3 
D      Nuclear pore complex
E        QC762_407260 MLP1; Protein mlp1	K09291 TPR; nucleoprotein TPR 
E        QC762_209930 GLE2; RNA export factor gle2	K14298 RAE1; mRNA export factor 
E        QC762_708300 hypothetical protein	K14298 RAE1; mRNA export factor 
E        QC762_407300 SEC13; GTPase-activating protein S13	K14004 SEC13; protein transport protein SEC13 
E        QC762_122290 NUP57; Nucleoporin nup57	K14308 NUP54; nuclear pore complex protein Nup54 
E        QC762_107900 NSP1; FG-nucleoporin nsp1	K14306 NUP62; nuclear pore complex protein Nup62 
E        QC762_306745 NIC96_2; nuclear pore complex subunit	K14309 NUP93; nuclear pore complex protein Nup93 
E        QC762_409030 hypothetical protein	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        QC762_112600 NUP84; Nucleoporin nup84	K14301 NUP107; nuclear pore complex protein Nup107 
E        QC762_402490 hypothetical protein	K14300 NUP133; nuclear pore complex protein Nup133 
E        QC762_710900 hypothetical protein	K14311 NUP188; nuclear pore complex protein Nup188 
E        QC762_606590 hypothetical protein	K14312 NUP155; nuclear pore complex protein Nup155 
E        QC762_113560 uncharacterized protein	K14303 NUP160; nuclear pore complex protein Nup160 
E        QC762_707590 hypothetical protein	K14310 NUP205; nuclear pore complex protein Nup205 
E        QC762_302350 NUP49; Nucleoporin nup49/NSP49 (Nuclear pore protein nup49/NSP49)	K14307 NUPL1; nucleoporin p58/p45 
E        QC762_309200 hypothetical protein	K14315 NDC1; nucleoporin NDC1 
E        QC762_303405 ALG7_1; tunicamycin resistance protein	K14299 SEH1; nucleoporin SEH1 
E        QC762_108250 uncharacterized protein	K18715 NUP159; nucleoporin NUP159 
E        QC762_001550 hypothetical protein	K18716 NUP42; nucleoporin NUP42 
E        QC762_702510 NUP82; Nucleoporin nup82	K18719 NUP82; nucleoporin NUP82 
E        QC762_403130 CDC31; Calcium-binding component of the spindle pole body (SPB) half-bridge	K16466 CETN3; centrin-3 
E        QC762_206050 uncharacterized protein	K18723 GLE1; nucleoporin GLE1 
E        QC762_112420 MEX67; nuclear mRNA export, poly(A)+RNA binding protein	K14284 NXF; nuclear RNA export factor 
E        QC762_209450 uncharacterized protein	K14285 NXT1_2; NTF2-related export protein 1/2 
E        QC762_211440 uncharacterized protein	K18724 POM34; nucleoporin POM34 
E        QC762_506100 hypothetical protein	K18725 POM152; nucleoporin POM152 
D      Ran-mediated transport factors
E        QC762_107290 GSP1; GTP-binding nuclear protein gsp1/Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        QC762_120850 ucp10; UBX domain-containing protein 10	K18726 FAF2; FAS-associated factor 2 
E        QC762_705590 CDC48; AAA ATPase cdc48	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        QC762_109020 rna1; Ran GAP Rna1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        QC762_102680 TIF45; eukaryotic translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        QC762_209170 uncharacterized protein	K03259 EIF4E; translation initiation factor 4E 
E        QC762_110440 TIF1; translation initiation factor eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        QC762_711170 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        QC762_705550 TIF3; Eukaryotic translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        QC762_0041010 DED1; DEAD-box ATP-dependent RNA helicase	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        QC762_119830 uncharacterized protein	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        QC762_300310 SMY2; kinesin-like protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        QC762_409240 PAB1; Protein phosphatase PP2A regulatory subunit B	K13126 PABPC; polyadenylate-binding protein 
E        QC762_122010 SKI2; Antiviral helicase ski2	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        QC762_605930 mug81; putative steryl acetyl hydrolase mug81	K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6] 
E        QC762_303080 TMA20; translation machinery-associated protein 20	K07575 MCTS; malignant T-cell-amplified sequence 
E        QC762_118740 TMA22; Translation machinery-associated protein 22	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        QC762_102180 uncharacterized protein	K14294 WIBG; partner of Y14 and mago 
E        QC762_212560 uncharacterized protein	K14411 MSI; RNA-binding protein Musashi 
E        QC762_406430 hypothetical protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        QC762_701210 DOM34; Translation factor pelota	K06965 PELO; protein pelota 
E        QC762_402600 hypothetical protein	K14396 PABPN1; polyadenylate-binding protein 2 
E        QC762_201600 DBP5; RNA helicase required for poly(A+) mRNA export	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        QC762_602190 SYF1; pre-mRNA-splicing factor syf1	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        QC762_203640 uncharacterized protein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        QC762_211550 uncharacterized protein	K11493 RCC1; regulator of chromosome condensation 
E        QC762_403350 hypothetical protein	K11493 RCC1; regulator of chromosome condensation 
E        QC762_600580 hypothetical protein	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        QC762_708260 ERF1; translation termination factor eRF1	K03265 ETF1; peptide chain release factor subunit 1 
E        QC762_409150 SUP35; translation termination factor GTPase eRF3	K03267 ERF3; peptide chain release factor subunit 3 
E        QC762_209730 NAM7; ATP-dependent RNA helicase	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        QC762_304250 NMD2; mRNA decay protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        QC762_604820 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
D      Protein phosphatase 2A
E        QC762_601940 PPH1; Serine/threonine-protein phosphatase PP2A catalytic subunit	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        QC762_706690 TPD3; protein phosphatase 2A structural subunit	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        QC762_114120 CDC55; protein phosphatase 2A regulatory subunit cdc55	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        QC762_211870 RTS1; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        QC762_300310 SMY2; kinesin-like protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        QC762_701540 hypothetical protein	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        QC762_114150 puf6; Pumilio y domain member 6	K14844 PUF6; pumilio homology domain family member 6 
E        QC762_110880 PBP2; PAB1 binding protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        QC762_709110 HEK2; RNA binding protein, heterogenous nuclear RNP-K like protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        QC762_205470 MYO2; Myosin type-2 heavy chain 1	K10357 MYO5; myosin V 
E        QC762_0055130 hypothetical protein	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
E        QC762_0063700 hypothetical protein	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
E        QC762_0078810 hypothetical protein	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
E        QC762_0096160 hypothetical protein	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
E        QC762_311410 hypothetical protein	K13210 FUBP; far upstream element-binding protein 
E        QC762_119720 TEF-1; translation elongation factor EF-1 alpha	K03231 EEF1A; elongation factor 1-alpha 
E        QC762_207250 TEF4_1; elongation factor EF-1 gamma subunit	K03233 EEF1G; elongation factor 1-gamma 
E        QC762_212200 TEF4_2; elongation factor EF-1 gamma subunit	K03233 EEF1G; elongation factor 1-gamma 
E        QC762_502060 hypothetical protein	K03233 EEF1G; elongation factor 1-gamma 
D      Other mRNA localization factors
E        QC762_206040 SSD1; Translational repressor	K18748 SSD1; protein SSD1 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        QC762_211400 exo2; exonuclease II Exo2	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        QC762_508910 ago1; Protein argonaute	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        QC762_102680 TIF45; eukaryotic translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        QC762_209170 uncharacterized protein	K03259 EIF4E; translation initiation factor 4E 
E        QC762_209730 NAM7; ATP-dependent RNA helicase	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        QC762_0041010 DED1; DEAD-box ATP-dependent RNA helicase	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        QC762_119830 uncharacterized protein	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        QC762_511400 DHH1; DExD/H-box ATP-dependent RNA helicase dhh1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        QC762_305970 hypothetical protein	K18749 LSM14; protein LSM14 
E        QC762_203610 uncharacterized protein	K18752 TNPO1; transportin-1 
E        QC762_118940 PKA4; cytochrome c oxidase subunit 1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        QC762_708890 TPK2_2; cAMP-dependent protein kinase catalytic subunit	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        QC762_113700 uncharacterized protein	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        QC762_711110 DCP2; mRNA-decapping enzyme subunit 2	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        QC762_308060 hypothetical protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        QC762_117870 LSM2; U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        QC762_701530 LSM3; U4/U6-U5 snRNP complex subunit lsm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        QC762_603649 hypothetical protein	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        QC762_205828 LSM5; RNA-binding protein lsm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        QC762_113980 LSM6; U4/U6-U5 snRNP complex subunit lsm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        QC762_120830 lsm7; U6 snRNP-associated protein Lsm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        QC762_111950 uncharacterized protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        QC762_205470 MYO2; Myosin type-2 heavy chain 1	K10357 MYO5; myosin V 
E        QC762_103600 TUB1_1; alpha-tubulin	K07374 TUBA; tubulin alpha 
E        QC762_310220 TUB1_2; alpha-tubulin	K07374 TUBA; tubulin alpha 
E        QC762_408360 CDC39; CCR4-NOT core subunit cdc39	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        QC762_603530 CDC36; transcriptional regulator	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        QC762_403020 NOT5; General negative regulator of transcription subunit 5	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        QC762_407170 NOT4; General negative regulator of transcription subunit 4	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        QC762_204080 CCR4; Glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        QC762_707660 POP2; CCR4-NOT core DEDD RNase subunit	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        QC762_409120 PAN2; poly(A)-specific ribonuclease	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        QC762_120840 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        QC762_608390 PAT1; DNA topoisomerase 2-associated protein pat1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
E        QC762_706510 EDC3; enhancer of mRNA decapping	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        QC762_304250 NMD2; mRNA decay protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        QC762_604820 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
E        QC762_116720 RPB7; DNA-directed RNA polymerase II subunit	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
D      Stress granule specific factors
E        QC762_710990 PUB1; E3 ubiquitin-protein ligase pub1	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        QC762_409240 PAB1; Protein phosphatase PP2A regulatory subunit B	K13126 PABPC; polyadenylate-binding protein 
E        QC762_707110 hypothetical protein	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        QC762_508440 hypothetical protein	K15026 EIF2A; translation initiation factor 2A 
E        QC762_504340 PRT1; Translation initiation factor 3 subunit b	K03253 EIF3B; translation initiation factor 3 subunit B 
E        QC762_110440 TIF1; translation initiation factor eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        QC762_206970 FAL1; RNA helicase	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        QC762_705550 TIF3; Eukaryotic translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        QC762_711170 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        QC762_0061540 cpc2; cross-pathway control WD-repeat protein cpc2	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        QC762_112420 MEX67; nuclear mRNA export, poly(A)+RNA binding protein	K14284 NXF; nuclear RNA export factor 
E        QC762_305080 HDA1; Histone deacetylase hda1	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        QC762_711110 DCP2; mRNA-decapping enzyme subunit 2	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        QC762_511400 DHH1; DExD/H-box ATP-dependent RNA helicase dhh1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        QC762_706510 EDC3; enhancer of mRNA decapping	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        QC762_608390 PAT1; DNA topoisomerase 2-associated protein pat1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
D      Lsm complex
E        QC762_308060 hypothetical protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        QC762_117870 LSM2; U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        QC762_701530 LSM3; U4/U6-U5 snRNP complex subunit lsm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        QC762_603649 hypothetical protein	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        QC762_205828 LSM5; RNA-binding protein lsm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        QC762_113980 LSM6; U4/U6-U5 snRNP complex subunit lsm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        QC762_120830 lsm7; U6 snRNP-associated protein Lsm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        QC762_111950 uncharacterized protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        QC762_211400 exo2; exonuclease II Exo2	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        QC762_605250 RAT1; 5'-3' exoribonuclease 2	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        QC762_0024390 uncharacterized protein	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        QC762_211000 CSL4; exosome 3'->5 exonuclease subunit ski4 (Csl4)	K07573 CSL4; exosome complex component CSL4 
E        QC762_402660 rrp4; Exosome complex component rrp4	K03679 RRP4; exosome complex component RRP4 
E        QC762_118890 RRP40; exosome non-catalytic core subunit rrp40	K03681 RRP40; exosome complex component RRP40 
E        QC762_105280 SKI6; Exosome non-catalytic core component	K11600 RRP41; exosome complex component RRP41 
E        QC762_102210 RRP46; exosome non-catalytic core subunit rrp46	K12590 RRP46; exosome complex component RRP46 
E        QC762_602090 MTR3; 3'-5'-exoribonuclease	K12587 MTR3; exosome complex component MTR3 
E        QC762_308610 RRP42; Exosome complex component rrp42	K12589 RRP42; exosome complex component RRP42 
E        QC762_114560 uncharacterized protein	K12586 RRP43; exosome complex component RRP43 
D      Exosome cofactors
E        QC762_112040 DIS3; exosome catalytic subunit dis3	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        QC762_509180 RRP6; exosome nuclease subunit	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        QC762_119120 uncharacterized protein	K12592 C1D; exosome complex protein LRP1 
D      TRAMP complex
E        QC762_409830 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        QC762_200200 uncharacterized protein	K12597 AIR1_2; protein AIR1/2 
E        QC762_305840 MTR4; ATP-dependent RNA helicase mtr4	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        QC762_122010 SKI2; Antiviral helicase ski2	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        QC762_508830 SKI3; Superkiller protein 3	K12600 SKI3; superkiller protein 3 
E        QC762_305740 rec14; Ski complex subunit Rec14	K12601 SKI8; superkiller protein 8 
D      Ccr4-NOT complex
E        QC762_204080 CCR4; Glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        QC762_408360 CDC39; CCR4-NOT core subunit cdc39	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        QC762_603530 CDC36; transcriptional regulator	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        QC762_403020 NOT5; General negative regulator of transcription subunit 5	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        QC762_407170 NOT4; General negative regulator of transcription subunit 4	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        QC762_707660 POP2; CCR4-NOT core DEDD RNase subunit	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        QC762_406940 rcd1; RNA-binding protein, CCR4-NOT complex subunit Rcd1	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        QC762_113470 uncharacterized protein	K12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120 
D      Pan complex
E        QC762_409120 PAN2; poly(A)-specific ribonuclease	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        QC762_120840 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        QC762_0024390 uncharacterized protein	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        QC762_710470 hypothetical protein	K26109 NRDE2; nuclear exosome regulator NRDE2 
E        QC762_705800 VTS1; Flap-structured DNA-binding and RNA-binding protein	K27407 VTS1; RNA-binding protein VTS1 
C    Other degradation factors
D      RNases
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        QC762_305020 hypothetical protein	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        QC762_114260 rex2; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        QC762_110540 ENO1; phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        QC762_114910 PFK1; 6-phosphofructokinase, alpha subunit	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        QC762_0094060 SSC1; Hsp70 ATPase ssc1	K04043 dnaK; molecular chaperone DnaK 
E        QC762_605750 HSP60; chaperonin	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        QC762_402660 rrp4; Exosome complex component rrp4	K03679 RRP4; exosome complex component RRP4 
E        QC762_211000 CSL4; exosome 3'->5 exonuclease subunit ski4 (Csl4)	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        QC762_105280 SKI6; Exosome non-catalytic core component	K11600 RRP41; exosome complex component RRP41 
E        QC762_308610 RRP42; Exosome complex component rrp42	K12589 RRP42; exosome complex component RRP42 
D      Others
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#Last updated: April 25, 2024