+F Repair protein KO
#
DNA Repair and Recombination Proteins - Pseudomonas putida DOT-T1E
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D T1E_2210 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D T1E_0976 phr; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E T1E_0270 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E T1E_3690 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E T1E_2532 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E T1E_1833 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E T1E_4300 DEAD_2 domain-containing protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D T1E_0313 mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_4212 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_4367 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_5607 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_4703 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D T1E_2210 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D T1E_0479 ada; methylated-DNA--protein-cysteine methyltransfera K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D T1E_0976 phr; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D T1E_2732 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D T1E_5192 alkB; 2OG-Fe K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E T1E_0270 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E T1E_0480 mag1; DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E T1E_3690 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E T1E_2532 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E T1E_0888 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E T1E_4686 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E T1E_1833 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E T1E_0334 xthA; exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E T1E_2711 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E T1E_4707 exoAA; exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E T1E_4327 exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E T1E_2855 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E T1E_1142 ligB; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E T1E_0739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E T1E_4757 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E T1E_2445 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E T1E_3481 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E T1E_5023 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E T1E_0040 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E T1E_3961 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E T1E_4757 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E T1E_1142 ligB; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E T1E_0739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F T1E_1936 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F T1E_1935 DNA-directed RNA polymerase subunit beta K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F T1E_3477 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F T1E_4012 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F T1E_1223 mfd; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E T1E_4976 mutS; DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E T1E_2595 mutL; DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E T1E_0219 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E T1E_2004 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E T1E_5744 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E T1E_4957 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E T1E_0872 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E T1E_1956 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E T1E_4710 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E T1E_1299 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E T1E_4913 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E T1E_4125 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E T1E_2200 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E T1E_0735 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E T1E_1142 ligB; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E T1E_0739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E T1E_3961 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E T1E_3483 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E T1E_4229 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E T1E_0849 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E T1E_0850 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E T1E_0848 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E T1E_4980 recA; Protein recA K03553 recA; recombination protein RecA
E T1E_5725 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E T1E_5726 ruvB; Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E T1E_5724 ruvC; Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E T1E_0160 priA; primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E T1E_0219 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E T1E_3574 SMC domain-containing protein K03546 sbcC; DNA repair protein SbcC/Rad50
E T1E_3575 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E T1E_4980 recA; Protein recA K03553 recA; recombination protein RecA
E T1E_0817 radA; DNA repair radA-like protein K04485 radA; DNA repair protein RadA/Sms
E T1E_0873 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF
E T1E_4003 recG; ATP-dependent DNA helicase recG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E T1E_2855 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E T1E_0294 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
E T1E_0733 recR; Recombination protein recR K06187 recR; recombination protein RecR
E T1E_0657 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E T1E_5756 rdgC; Recombination-associated protein rdgC K03554 rdgC; recombination associated protein RdgC
E T1E_5725 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E T1E_5726 ruvB; Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E T1E_5724 ruvC; Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E T1E_3574 SMC domain-containing protein K03546 sbcC; DNA repair protein SbcC/Rad50
E T1E_3575 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
E T1E_0226 yjgR; protein of unknown function DUF853, NPT K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E T1E_5620 Ku family containing protein K10979 ku; DNA end-binding protein Ku
E T1E_5615 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F T1E_3016 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F T1E_0874 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F T1E_0607 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F T1E_0487 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F T1E_1473 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F T1E_4000 histone family protein DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
F T1E_1952 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F T1E_5379 hupB; histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F T1E_2855 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F T1E_0294 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
F T1E_0733 recR; Recombination protein recR K06187 recR; recombination protein RecR
F T1E_1142 ligB; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F T1E_0739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F T1E_3699 DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F T1E_3415 ihfA; Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F T1E_3023 ihfB; Integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F T1E_0219 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F T1E_4084 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F T1E_2445 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F T1E_3481 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F T1E_5023 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D T1E_2962 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D T1E_4201 umuC; DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D T1E_4200 umuD; putative prophage repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D T1E_4980 recA; Protein recA K03553 recA; recombination protein RecA
D T1E_1218 lexA-1; LexA repressor 1 K01356 lexA; repressor LexA [EC:3.4.21.88]
D T1E_5672 lexA-2; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D T1E_0657 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D T1E_5287 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D T1E_5671 hypothetical protein K14160 imuA; protein ImuA
D T1E_5670 hypothetical protein K14161 imuB; protein ImuB
D T1E_5669 Error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D T1E_3483 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D T1E_4229 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D T1E_4981 recX; Regulatory protein recX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D T1E_2774 rep; ATP-dependent DNA helicase rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D T1E_1862 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D T1E_1844 DEAD/DEAH box helicase domain-containing protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D T1E_1643 lhr; DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D T1E_4494 DEAD/DEAH box helicase domain-containing protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D T1E_0313 mutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_4212 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_4367 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_5607 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D T1E_4703 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D T1E_4035 nrdA; Ribonucleoside-diphosphate reductase subunit alp K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D T1E_4037 nrdB; ribonucleotide-diphosphate reductase subunit bet K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024