+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Plasmodium reichenowi
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E PRSY57_1013800 MO15-related protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E PRSY57_1413900 RNA guanylyltransferase K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]
D Cap binding complex
E PRSY57_0413000 nuclear cap-binding protein, putative K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E PRSY57_0107000 mRNA cleavage factor-like protein, putative K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
D Pre-mRNA cleavage factor IIm (CFIIm)
E PRSY57_0820900 clp1-related protein, putative K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
D Cleavage and polyadenylation specificity factor (CPSF) complex
E PRSY57_1437800 cleavage and polyadenylation specificity factor, putative K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E PRSY57_1243200 microtubule associated katanin, putative K14962 WDR82; COMPASS component SWD2
E PRSY57_1413700 serine/threonine protein phosphatase PP1, putative K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E PRSY57_0618900 cleavage stimulation factor subunit 1, putative K14406 CSTF1; cleavage stimulation factor subunit 1
D U7-dependent histone pre-mRNA processing factors
E PRSY57_1414100 small nuclear ribonucleoprotein-associated protein B, putative K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E PRSY57_1349200 small nuclear ribonucleoprotein E, putative K11097 SNRPE; small nuclear ribonucleoprotein E
E PRSY57_1125400 small nuclear ribonucleoprotein F, putative K11098 SNRPF; small nuclear ribonucleoprotein F
E PRSY57_0821600 small nuclear ribonucleoprotein G, putative K11099 SNRPG; small nuclear ribonucleoprotein G
E PRSY57_1437800 cleavage and polyadenylation specificity factor, putative K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E PRSY57_0518100 hypothetical protein K18710 SLBP; histone RNA hairpin-binding protein
D DRB sensitivity inducing factor (DSIF) complex
E PRSY57_1029300 transcription elongation factor SPT4, putative K15171 SUPT4H1; transcription elongation factor SPT4
E PRSY57_0609600 transcription elongation factor SPT5, putative K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E PRSY57_0726300 mRNA (N6-adenosine)-methyltransferase, putative K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E PRSY57_1234700 mRNA methyltransferase, putative K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E PRSY57_1230100 hypothetical protein K22824 WTAP; pre-mRNA-splicing regulator WTAP
D Poly(A) addition factors
E PRSY57_0624000 poly(A) polymerase PAP, putative K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
C Other processing factors
D PRSY57_1466700 DNA/RNA-binding protein KIN17, putative K13102 KIN; DNA/RNA-binding protein KIN17
D PRSY57_0621500 coronin binding protein, putative K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E PRSY57_1405300 RNA-binding protein, putative K12876 RBM8A; RNA-binding protein 8A
E PRSY57_0722400 mago nashi protein-like protein K12877 MAGOH; protein mago nashi
E PRSY57_0614400 RNA and export factor binding protein, putative K12881 THOC4; THO complex subunit 4
E PRSY57_0002500 ATP-dependent RNA helicase UAP56 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E PRSY57_0419900 eukaryotic initiation factor, putative K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
D TREX complex
E PRSY57_0614400 RNA and export factor binding protein, putative K12881 THOC4; THO complex subunit 4
D TREX-2 complex
E PRSY57_0719000 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
D Nuclear pore complex
E PRSY57_1230000 protein transport protein SEC13, putative K14004 SEC13; protein transport protein SEC13
D Ran-mediated transport factors
E PRSY57_1116100 GTP-binding nuclear protein RAN/TC4, putative K07936 RAN; GTP-binding nuclear protein Ran
E PRSY57_1427200 conserved protein, unknown function K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E PRSY57_0932700 UBX domain, putative K18726 FAF2; FAS-associated factor 2
E PRSY57_0617800 cell division cycle protein 48-like protein K13525 VCP; transitional endoplasmic reticulum ATPase
E PRSY57_0302200 exportin-1, putative K14290 XPO1; exportin-1
E PRSY57_0908200 Ran-binding protein, putative K18460 XPO7; exportin-7
D eIF4F and regulatory proteins
E PRSY57_0314400 translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E PRSY57_1467900 helicase 45 K03257 EIF4A; translation initiation factor 4A
E PRSY57_0809900 RNA helicase, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E PRSY57_1030800 DEAD/DEAH box helicase, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E PRSY57_1223600 polyadenylate-binding protein, putative K13126 PABPC; polyadenylate-binding protein
E PRSY57_0813000 translation initiation factor SUI1, putative K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E PRSY57_1208300 hypothetical protein K14294 WIBG; partner of Y14 and mago
E PRSY57_0412000 RNA-binding protein, putative K14411 MSI; RNA-binding protein Musashi
E PRSY57_0719300 PelOta protein-like protein K06965 PELO; protein pelota
E PRSY57_0921900 RNA-binding protein, putative K14396 PABPN1; polyadenylate-binding protein 2
E PRSY57_1458300 ATP-dependent RNA helicase DBP5 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E PRSY57_1235100 pre-mRNA-splicing factor SYF1, putative K12867 SYF1; pre-mRNA-splicing factor SYF1
E PRSY57_0910500 hypothetical protein K18732 SARNP; SAP domain-containing ribonucleoprotein
E PRSY57_0709700 regulator of chromosome condensation, putative K11493 RCC1; regulator of chromosome condensation
C Surveillance factors
D Surveillance complex
E PRSY57_0211200 peptide chain release factor subunit 1, putative K03265 ETF1; peptide chain release factor subunit 1
E PRSY57_1121800 translation elongation factor EF-1, subunit alpha, putative K03267 ERF3; peptide chain release factor subunit 3
E PRSY57_1004900 putative regulator of nonsense transcripts K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E PRSY57_0923800 hypothetical protein K14327 UPF2; regulator of nonsense transcripts 2
D Protein phosphatase 2A
E PRSY57_0923400 protein phosphatase-beta K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E PRSY57_1355300 phosphatase 2A regulatory subunit-related protein, putative K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
D Other surveillance factors
E PRSY57_0309000 SECIS-binding protein 2, putative K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
C Factors involved in mRNA localization
D Cargo complex
E PRSY57_0619700 mRNA binding PUM-HD domain protein-like protein K14844 PUF6; pumilio homology domain family member 6
E PRSY57_0203900 3'-5' exonuclease, putative K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
D Trans-acting binding proteins
E PRSY57_1337300 elongation factor 1-gamma, putative K03233 EEF1G; elongation factor 1-gamma
D Other mRNA localization factors
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E PRSY57_1104800 exonuclease, putative K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E PRSY57_0314400 translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E PRSY57_1004900 putative regulator of nonsense transcripts K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E PRSY57_0809900 RNA helicase, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E PRSY57_1030800 DEAD/DEAH box helicase, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E PRSY57_0320100 ATP-dependent RNA helicase DDX6, putative K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E PRSY57_1474000 trailer hitch-like protein K18749 LSM14; protein LSM14
E PRSY57_0626100 transportin K18752 TNPO1; transportin-1
E PRSY57_0932800 cAMP-dependent protein kinase catalytic subunit K04345 PKA; protein kinase A [EC:2.7.11.11]
D P-body specific factors
E PRSY57_1307900 mRNA-decapping enzyme 2, putative K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E PRSY57_1122800 U6 snRNA-associated Sm-like protein LSm1, putative K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E PRSY57_0519400 U6 snRNA-associated Sm-like protein LSm2, putative K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E PRSY57_0819200 U6 snRNA-associated Sm-like protein LSm3, putative K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E PRSY57_1105500 U6 snRNA-associated Sm-like protein LSm4, putative K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E PRSY57_1442600 U6 snRNA-associated Sm-like protein LSm5, putative K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E PRSY57_1324000 U6 snRNA-associated Sm-like protein LSm6, putative K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E PRSY57_1208500 U6 snRNA-associated Sm-like protein LSm7, putative K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E PRSY57_0828600 U6 snRNA-associated Sm-like protein LSm8, putative K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E PRSY57_0901800 alpha tubulin 1 K07374 TUBA; tubulin alpha
E PRSY57_1102300 CCR4-NOT transcription complex subunit 1, putative K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E PRSY57_1127100 CCR4-NOT transcription complex subunit 2, putative K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E PRSY57_0518600 carbon catabolite repressor protein 4, putative K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E PRSY57_0810600 CCR4-associated factor 1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E PRSY57_0923800 hypothetical protein K14327 UPF2; regulator of nonsense transcripts 2
E PRSY57_1026700 DNA-directed RNA polymerase II, putative K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
D Stress granule specific factors
E PRSY57_1223600 polyadenylate-binding protein, putative K13126 PABPC; polyadenylate-binding protein
E PRSY57_1437300 eukaryotic translation initiation factor eIF2A, putative K15026 EIF2A; translation initiation factor 2A
E PRSY57_0008400 eukaryotic translation initiation factor, putative K03253 EIF3B; translation initiation factor 3 subunit B
E PRSY57_1467900 helicase 45 K03257 EIF4A; translation initiation factor 4A
E PRSY57_0419900 eukaryotic initiation factor, putative K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E PRSY57_0826000 receptor for activated c kinase K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E PRSY57_1307900 mRNA-decapping enzyme 2, putative K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E PRSY57_0320100 ATP-dependent RNA helicase DDX6, putative K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D Lsm complex
E PRSY57_1122800 U6 snRNA-associated Sm-like protein LSm1, putative K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E PRSY57_0519400 U6 snRNA-associated Sm-like protein LSm2, putative K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E PRSY57_0819200 U6 snRNA-associated Sm-like protein LSm3, putative K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E PRSY57_1105500 U6 snRNA-associated Sm-like protein LSm4, putative K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E PRSY57_1442600 U6 snRNA-associated Sm-like protein LSm5, putative K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E PRSY57_1324000 U6 snRNA-associated Sm-like protein LSm6, putative K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E PRSY57_1208500 U6 snRNA-associated Sm-like protein LSm7, putative K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E PRSY57_0828600 U6 snRNA-associated Sm-like protein LSm8, putative K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E PRSY57_1104800 exonuclease, putative K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E PRSY57_0907500 exoribonuclease, putative K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
C 3'-5' decay
D Core exosome factors
E PRSY57_0717200 exosome complex component CSL4, putative K07573 CSL4; exosome complex component CSL4
E PRSY57_0407800 exosome complex component RRP4, putative K03679 RRP4; exosome complex component RRP4
E PRSY57_1306000 exosome complex component RRP40, putative K03681 RRP40; exosome complex component RRP40
E PRSY57_1427100 exosome complex exonuclease RRP41, putative K11600 RRP41; exosome complex component RRP41
E PRSY57_1339100 exosome complex component RRP42, putative K12589 RRP42; exosome complex component RRP42
E PRSY57_1363400 exosome complex component RRP45, putative K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E PRSY57_1358200 exosome complex exonuclease RRP44, putative K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E PRSY57_1444800 hypothetical protein K12592 C1D; exosome complex protein LRP1
E PRSY57_0901500 DEAD/DEAH box helicase, putative K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E PRSY57_1331400 nucleotidyltransferase, putative K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E PRSY57_0600700 ATP-dependent RNA helicase, putative K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
D Ccr4-NOT complex
E PRSY57_0518600 carbon catabolite repressor protein 4, putative K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E PRSY57_1102300 CCR4-NOT transcription complex subunit 1, putative K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E PRSY57_1127100 CCR4-NOT transcription complex subunit 2, putative K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E PRSY57_0810600 CCR4-associated factor 1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E PRSY57_0506800 cell differentiation protein rcd1, putative K12606 RCD1; CCR4-NOT transcription complex subunit 9
E PRSY57_1433300 ABC transporter, putative K12608 CAF16; CCR4-NOT complex subunit CAF16
D Pan complex
D Other 3'-5' decay factors
E PRSY57_1442800 poly(A)-specific ribonuclease PARN, putative K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E PRSY57_0820600 ATP-dependent RNA helicase prh1, putative K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
C Other degradation factors
D RNases
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AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
D Helicases
D Other RNA degradosome components
E PRSY57_1015300 enolase, putative K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C Other RNA degradation factors
D Chaperones
E PRSY57_1132400 heat shock protein 70, putative K04043 dnaK; molecular chaperone DnaK
E PRSY57_1015000 heat shock protein 60 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E PRSY57_1231400 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E PRSY57_0407800 exosome complex component RRP4, putative K03679 RRP4; exosome complex component RRP4
E PRSY57_0717200 exosome complex component CSL4, putative K07573 CSL4; exosome complex component CSL4
D Cofactors
E PRSY57_1427100 exosome complex exonuclease RRP41, putative K11600 RRP41; exosome complex component RRP41
E PRSY57_1339100 exosome complex component RRP42, putative K12589 RRP42; exosome complex component RRP42
D Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024