+F Repair protein KO
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DNA Repair and Recombination Proteins - Plasmodium relictum
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PRELSG_1018500 deoxyribodipyrimidine photo-lyase, putative K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PRELSG_1336100 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PRELSG_1213700 DNA-3-methyladenine glycosylase, putative K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PRELSG_0926600 A/G-specific adenine glycosylase, putative K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PRELSG_1133300 endonuclease III homologue, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E PRELSG_1264300 APN1; apurinic/apyrimidinic endonuclease Apn1, putative K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F PRELSG_0600400 DNA polymerase delta catalytic subunit, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F PRELSG_0827600 DNA polymerase epsilon subunit b, putative K02328 POLD2; DNA polymerase delta subunit 2
E DNA polymerase epsilon complex
F PRELSG_1118000 DNA polymerase epsilon, catalytic subunit a, putative K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F PRELSG_1450300 DNA polymerase epsilon subunit b, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
E PRELSG_1108800 PCNA; proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
E PRELSG_1442200 PCNA2; proliferating cell nuclear antigen 2, putative K04802 PCNA; proliferating cell nuclear antigen
E PRELSG_0305700 FEN1; flap endonuclease 1, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E PRELSG_1401800 LigI; DNA ligase I, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E PRELSG_1107400 PNKP; bifunctional polynucleotide phosphatase/kinase, putative K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F PRELSG_0809600 DNA repair protein RAD23, putative K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F PRELSG_0819000 RBX1; E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E NER4 complex
F PRELSG_1466100 DNA repair protein rhp16, putative K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F PRELSG_0819900 RPB1; DNA-directed RNA polymerase II subunit RPB1, putative K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F PRELSG_0404400 RPB2; DNA-directed RNA polymerase II subunit RPB2, putative K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F PRELSG_0720600 RPB3; DNA-directed RNA polymerase II subunit RPB3, putative K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F PRELSG_0416400 DNA-directed RNA polymerase II 16 kDa subunit, putative K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F PRELSG_1105700 DNA-directed RNA polymerase II, putative K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F PRELSG_0832400 DNA-directed RNA polymerase subunit I, putative K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F PRELSG_0611000 DNA-directed RNA polymerase II, putative K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F PRELSG_1429800 RNA polymerase subunit 8c, putative K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F PRELSG_0206800 DNA-directed RNA polymerase 2, putative K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F PRELSG_0106100 DNA-directed RNA polymerase 2 8.2 kDa polypeptide, putative K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F PRELSG_1402700 DNA-directed RNA polymerase 2, putative K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F PRELSG_1255200 transcription activator, putative K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F PRELSG_0819000 RBX1; E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Other TCR factor
F PRELSG_0712100 zinc binding protein, putative K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E PRELSG_0620100 DNA repair helicase RAD25, putative K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E PRELSG_0732000 XPD; TFIIH basal transcription factor complex helicase XPD subunit, putative K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E PRELSG_1412800 P44; general transcription factor IIH subunit 2, putative K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E PRELSG_1116900 TFB4; RNA polymerase II transcription factor B subunit 4, putative K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E PRELSG_1459300 TFB2; RNA polymerase II transcription factor B subunit 2, putative K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E PRELSG_1239100 TFB5; RNA polymerase II transcription factor B subunit 5, putative K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E PRELSG_0812300 MRK; MO15-related protein kinase, putative K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E PRELSG_1217100 CYC1; cyclin homologue, putative K06634 CCNH; cyclin H
E PRELSG_1019900 MAT1; CDK-activating kinase assembly factor, putative K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E PRELSG_0306800 RPA1; replication protein A1, large subunit, putative K07466 RFA1; replication factor A1
E PRELSG_1238900 RPA3; replication factor A protein 3, putative K10740 RPA3; replication factor A3
D Other NER factors
E PRELSG_0418600 ERCC1 nucleotide excision repair protein, putative K10849 ERCC1; DNA excision repair protein ERCC-1
E PRELSG_0009500 ERCC4; DNA repair endonuclease, putative K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E PRELSG_0415900 RAD2; DNA repair protein RAD2, putative K10846 ERCC5; DNA excision repair protein ERCC-5
E PRELSG_1401800 LigI; DNA ligase I, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E PRELSG_0104600 DNA mismatch repair protein MSH2, putative K08735 MSH2; DNA mismatch repair protein MSH2
E PRELSG_1323600 MSH2-1; DNA mismatch repair protein MSH2, putative K08735 MSH2; DNA mismatch repair protein MSH2
E PRELSG_1027000 MSH6; DNA mismatch repair protein MSH6, putative K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E PRELSG_0914600 MLH; DNA mismatch repair protein MLH, putative K08734 MLH1; DNA mismatch repair protein MLH1
E PRELSG_0214600 PMS1; DNA mismatch repair protein PMS1, putative K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E PRELSG_0600400 DNA polymerase delta catalytic subunit, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E PRELSG_0827600 DNA polymerase epsilon subunit b, putative K02328 POLD2; DNA polymerase delta subunit 2
D RPA (replication factor A)
E PRELSG_0306800 RPA1; replication protein A1, large subunit, putative K07466 RFA1; replication factor A1
E PRELSG_1238900 RPA3; replication factor A protein 3, putative K10740 RPA3; replication factor A3
D RFC (replication factor C)
E PRELSG_0400400 replication factor C subunit 1, putative K10754 RFC1; replication factor C subunit 1
E PRELSG_1456800 replication factor C subunit 4, putative K10755 RFC2_4; replication factor C subunit 2/4
E PRELSG_0402000 replication factor C subunit 2, putative K10755 RFC2_4; replication factor C subunit 2/4
E PRELSG_0908100 RFC5; replication factor C subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5
E PRELSG_1217600 RFC3; replication factor C3, putative K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E PRELSG_1108800 PCNA; proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
E PRELSG_1442200 PCNA2; proliferating cell nuclear antigen 2, putative K04802 PCNA; proliferating cell nuclear antigen
E PRELSG_1401800 LigI; DNA ligase I, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E PRELSG_0209100 MRE11; double-strand break repair protein MRE11, putative K10865 MRE11; double-strand break repair protein MRE11
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E PRELSG_0209100 MRE11; double-strand break repair protein MRE11, putative K10865 MRE11; double-strand break repair protein MRE11
D BRCA complex
E PRELSG_0904600 RAD51; DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E PRELSG_0904600 RAD51; DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
D Rad52 family proteins
D Rad54 family proteins
E PRELSG_0114500 RAD54; DNA repair protein RAD54, putative K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
E PRELSG_0716100 RECQ1; ATP-dependent DNA helicase Q1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E PRELSG_0716100 RECQ1; ATP-dependent DNA helicase Q1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E PRELSG_1250800 TOP3; DNA topoisomerase 3, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E PRELSG_0306800 RPA1; replication protein A1, large subunit, putative K07466 RFA1; replication factor A1
E PRELSG_1238900 RPA3; replication factor A protein 3, putative K10740 RPA3; replication factor A3
D Protein phosphatase 4
E PRELSG_0725300 PPP4; serine/threonine protein phosphatase 4, putative K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
D AP-5 complex
E PRELSG_0806000 conserved Plasmodium protein, unknown function K19024 AP5S1; AP-5 complex subunit sigma-1
D SMC5-SMC6 complex
E PRELSG_0920600 conserved Plasmodium protein, unknown function K22803 SMC5; structural maintenance of chromosomes protein 5
D Other HR factors
E PRELSG_0201600 conserved Plasmodium protein, unknown function K10881 SHFM1; 26 proteasome complex subunit DSS1
E PRELSG_1455100 HD superfamily phosphohydrolase protein, putative K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E PRELSG_0807300 metallopeptidase, putative K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
E PRELSG_0209100 MRE11; double-strand break repair protein MRE11, putative K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
E PRELSG_0716100 RECQ1; ATP-dependent DNA helicase Q1, putative K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E PRELSG_1250800 TOP3; DNA topoisomerase 3, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E PRELSG_0904600 RAD51; DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
C Other DSBR factors
D Protein phosphatase 6
E PRELSG_0821200 PPP6; serine/threonine protein phosphatase 6, putative K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E PRELSG_1213600 conserved Plasmodium protein, unknown function K23314 WRAP53; telomerase Cajal body protein 1
E PRELSG_0617300 WD-repeat protein, putative K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D PRELSG_1424900 ubiquitin-conjugating enzyme, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D PRELSG_0818800 ubiquitin-conjugating enzyme, putative K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D PRELSG_1254500 RAD5; DNA repair protein RAD5, putative K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D PRELSG_0830000 ubiquitin-conjugating enzyme E2, putative K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D PRELSG_1004700 UBC13; ubiquitin-conjugating enzyme E2 N, putative K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D PRELSG_1108800 PCNA; proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
D PRELSG_1442200 PCNA2; proliferating cell nuclear antigen 2, putative K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
D PRELSG_1456800 replication factor C subunit 4, putative K10755 RFC2_4; replication factor C subunit 2/4
D PRELSG_0402000 replication factor C subunit 2, putative K10755 RFC2_4; replication factor C subunit 2/4
D PRELSG_0908100 RFC5; replication factor C subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5
D PRELSG_1217600 RFC3; replication factor C3, putative K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
D PRELSG_1242400 conserved protein, unknown function K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D PRELSG_0505800 14-3-3 protein, putative K06630 YWHAE; 14-3-3 protein epsilon
D PRELSG_1108500 14-3-3 protein, putative K06630 YWHAE; 14-3-3 protein epsilon
D PRELSG_1223400 VPS4; vacuolar protein sorting-associated protein 4, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D PRELSG_1222200 exonuclease V, mitochondrial, putative K17815 EXO5; exonuclease V [EC:3.1.-.-]
C Helicases
C PSO4 complex
D PRELSG_0827000 PRPF19; pre-mRNA-processing factor 19, putative K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D PRELSG_0617400 Myb2; myb2 transcription factor, putative K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D PRELSG_1133700 conserved Plasmodium protein, unknown function K12861 BCAS2; pre-mRNA-splicing factor SPF27
D PRELSG_0833400 golgi organization and biogenesis factor, putative K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D PRELSG_0924100 dUTPase; deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D PRELSG_1313800 ribonucleoside-diphosphate reductase, large subunit, putative K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D PRELSG_0813700 ribonucleotide reductase small subunit, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D PRELSG_1345300 RNR; ribonucleotide reductase small subunit, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PRELSG_1018500 deoxyribodipyrimidine photo-lyase, putative K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PRELSG_1336100 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PRELSG_1213700 DNA-3-methyladenine glycosylase, putative K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PRELSG_0926600 A/G-specific adenine glycosylase, putative K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PRELSG_1133300 endonuclease III homologue, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E PRELSG_1017900 UvrD; ATP-dependent DNA helicase UvrD, putative K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F PRELSG_1208000 DNA-directed RNA polymerase, alpha subunit, putative K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F PRELSG_1405400 DNA-directed RNA polymerase alpha chain, putative K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E PRELSG_1017900 UvrD; ATP-dependent DNA helicase UvrD, putative K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PRELSG_1023700 SSB; single-stranded DNA-binding protein, putative K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F PRELSG_1438900 DNA gyrase subunit A, putative K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F PRELSG_1455600 GyrB; DNA gyrase subunit B, putative K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D PRELSG_1023700 SSB; single-stranded DNA-binding protein, putative K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D PRELSG_0924100 dUTPase; deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024