+F Repair protein KO
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DNA Repair and Recombination Proteins - Paenibacillus roseipurpureus
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MJB10_02345 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MJB10_13700 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MJB10_02290 mutY; (GenBank) A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MJB10_14590 nth; (GenBank) endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E MJB10_10840 helicase-associated domain-containing protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E MJB10_26000 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C SOSS complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MJB10_04220 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJB10_19725 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJB10_11580 dut; (GenBank) dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MJB10_02345 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MJB10_24020 methylated-DNA--[protein]-cysteine S-methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MJB10_13700 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MJB10_20910 mismatch-specific DNA-glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E MJB10_24030 DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MJB10_02290 mutY; (GenBank) A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MJB10_13510 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MJB10_14075 DNA-formamidopyrimidine glycosylase family protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MJB10_19510 mutM; (GenBank) DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MJB10_14590 nth; (GenBank) endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MJB10_25365 exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E MJB10_14070 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E MJB10_22060 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E MJB10_07210 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MJB10_00825 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MJB10_19515 polA; (GenBank) DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MJB10_00730 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E MJB10_00725 uvrB; (GenBank) excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E MJB10_06015 uvrC; (GenBank) excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E MJB10_00820 pcrA; (GenBank) DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_01680 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_02960 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_23115 helD; (GenBank) RNA polymerase recycling motor HelD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_19515 polA; (GenBank) DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MJB10_00825 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MJB10_25010 rpoB; (GenBank) DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MJB10_25005 rpoC; (GenBank) DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MJB10_24830 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MJB10_10920 rpoZ; (GenBank) DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MJB10_01000 mfd; (GenBank) transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MJB10_14255 mutS; (GenBank) DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E MJB10_21255 endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E MJB10_15615 xseA; (GenBank) exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MJB10_15610 xseB; (GenBank) exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MJB10_19895 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MJB10_11510 PolC-type DNA polymerase III K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E MJB10_00010 dnaN; (GenBank) DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MJB10_09725 holA; (GenBank) DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MJB10_00885 holB; (GenBank) DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MJB10_25195 dnaX; (GenBank) DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MJB10_00825 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MJB10_00820 pcrA; (GenBank) DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_01680 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_02960 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_23115 helD; (GenBank) RNA polymerase recycling motor HelD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJB10_26520 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MJB10_11685 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA
E MJB10_07135 ruvA; (GenBank) Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MJB10_07140 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MJB10_07130 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MJB10_09855 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E MJB10_09850 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MJB10_11685 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA
E MJB10_25120 radA; (GenBank) DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MJB10_00020 recF; (GenBank) DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E MJB10_11005 recG; (GenBank) ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MJB10_07210 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MJB10_09955 recO; (GenBank) DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MJB10_25185 recR; (GenBank) recombination mediator RecR K06187 recR; recombination protein RecR
E MJB10_15580 recN; (GenBank) DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MJB10_07135 ruvA; (GenBank) Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MJB10_07140 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MJB10_07130 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E MJB10_09845 addA; (GenBank) helicase-exonuclease AddAB subunit AddA K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E MJB10_09840 addB; (GenBank) helicase-exonuclease AddAB subunit AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E MJB10_09855 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E MJB10_09850 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E MJB10_22880 Ku protein K10979 ku; DNA end-binding protein Ku
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MJB10_00035 gyrA; (GenBank) DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MJB10_00030 gyrB; (GenBank) DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MJB10_11255 topA; (GenBank) type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MJB10_01025 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F MJB10_15085 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MJB10_07210 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MJB10_09955 recO; (GenBank) DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MJB10_25185 recR; (GenBank) recombination mediator RecR K06187 recR; recombination protein RecR
F MJB10_00825 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MJB10_25460 recQ; (GenBank) DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MJB10_00730 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F MJB10_00725 uvrB; (GenBank) excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MJB10_11025 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MJB10_18950 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D MJB10_11685 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA
D MJB10_14145 lexA; (GenBank) transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D MJB10_15580 recN; (GenBank) DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MJB10_26520 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJB10_11690 RecX family transcriptional regulator K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MJB10_11930 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D MJB10_14835 dinG; (GenBank) ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MJB10_04220 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJB10_19725 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJB10_11580 dut; (GenBank) dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MJB10_18315 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MJB10_20895 nrdE; (GenBank) class 1b ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MJB10_20890 nrdF; (GenBank) class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MJB10_11545 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 23, 2026