+C Two-component system KO
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Two-Component System - Proteus sp. CD3
%
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C BTA34_01985 phoR; two-component system sensor histidine kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C BTA34_01980 phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
C BTA34_05570 sensor protein PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C BTA34_05575 two-component system response regulator PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
B EnvZ-OmpR (osmotic stress response)
C BTA34_15740 two-component system sensor histidine kinase EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C BTA34_15735 two-component system response regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
B CpxA-CpxR (envelope stress response)
C BTA34_17185 two-component system sensor histidine kinase CpxA K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
C BTA34_17190 DNA-binding response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
C BTA34_09490 two-component system sensor histidine kinase BaeA K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
C BTA34_09495 two-component system response regulator BaeR K07664 baeR; two-component system, OmpR family, response regulator BaeR
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C BTA34_07890 two-component system sensor histidine kinase KdbD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C BTA34_07895 two-component system response regulator KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
C BTA34_01425 aerobic respiration two-component sensor histidine kinase ArcB K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
C BTA34_01675 two-component system response regulator ArcA K07773 arcA; two-component system, OmpR family, aerobic respiration control protein ArcA
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C BTA34_10130 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
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ANarL family
B NarX-NarL (nitrate respiration)
C BTA34_00835 two-component system sensor histidine kinase NarX K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C BTA34_00830 two-component system response regulator NarL K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
C BTA34_09300 DNA-binding response regulator K07685 narP; two-component system, NarL family, nitrate/nitrite response regulator NarP
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
C BTA34_02670 MASE1 sensor histidine kinase K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]
C BTA34_02675 DNA-binding response regulator K20264 fusR; two-component system, NarL family, response regulator FusR
B RcsC-RcsD-RcsB (capsule synthesis)
C BTA34_10315 two-component system sensor histidine kinase/response regulator K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C BTA34_10310 DNA-binding response regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
B BarA-UvrY (central carbon metabolism)
C BTA34_09135 response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C BTA34_00260 sensor histidine kinase K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C BTA34_00255 two-component system response regulator YehT K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C BTA34_15695 two-component system sensor histidine kinase NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C BTA34_15700 nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
C BTA34_11115 two-component sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
C BTA34_11105 two-component system response regulator GlrR K07715 glrR; two-component system, NtrC family, response regulator GlrR
B PgtB-PgtA (phosphoglycerate transport)
C BTA34_13985 two-component sensor histidine kinase K08475 pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]
C BTA34_13980 two-component system response regulator K08476 pgtA; two-component system, NtrC family, phosphoglycerate transport system response regulator PgtA
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C BTA34_09945 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C BTA34_09915 two-component system response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C BTA34_09920 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
C BTA34_10055 sensor histidine kinase K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
C BTA34_10060 DNA-binding response regulator K13041 ttrR; two-component system, LuxR family, response regulator TtrR
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C BTA34_08940 two-component system response regulator RssB K02485 rssB; two-component system, response regulator
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023