+C	Cytokine	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Cytokines and Neuropeptides - Pyrgilauda ruficollis (rufous-necked snowfinch)</h2>
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A<b>Cytokines</b>
B  Interleukins
C    121359483 IL1B; interleukin-1 beta	K04519 IL1B; interleukin 1 beta 
C    121361464 interleukin-4-like	K05430 IL4; interleukin 4 
C    121353190 IL6; interleukin-6	K05405 IL6; interleukin 6 
C    121351959 IL7; interleukin-7	K05431 IL7; interleukin 7 
C    121349783 IL10; interleukin-10	K05443 IL10; interleukin 10 
C    121365592 IL12B; interleukin-12 subunit beta	K05425 IL12B; interleukin 12B 
C    121350446 IL15; interleukin-15 isoform X1	K05433 IL15; interleukin 15 
C    121354597 IL16; pro-interleukin-16 isoform X1	K22628 IL16; interleukin 16 
C    121360831 IL17A; interleukin-17A	K05489 IL17A; interleukin 17A 
C    121365573 IL17B; interleukin-17B isoform X1	K05490 IL17B; interleukin 17B 
C    121362460 IL17C; interleukin-17C	K05491 IL17C; interleukin 17C 
C    121364244 IL17D; interleukin-17D isoform X1	K05492 IL17D; interleukin 17D 
C    121360771 interleukin-17F-like	K05494 IL17F; interleukin 17F 
C    121355739 IL18; interleukin-18	K05482 IL18; interleukin 18 
C    121349765 interleukin-20-like	K22667 IL20; interleukin 20 
C    121361518 IL21; interleukin-21	K05434 IL21; interleukin 21 
C    121352607 IL22; interleukin-22	K05445 IL22; interleukin 22 
C    121358948 IL23A; interleukin-23 subunit alpha	K05426 IL23A; interleukin 23 subunit alpha 
C    121352489 IL26; interleukin-26	K05446 IL26; interleukin 26 
C    121349909 EBI3; interleukin-27 subunit beta	K24476 EBI3; interleukin 27 subunit beta 
C    121348812 IL34; interleukin-34	K22633 IL34; interleukin 34 
C    121352741 interleukin-36 receptor antagonist protein-like	K05483 IL36RN; interleukin 36 receptor antagonist protein 
B  Interferons
C    121363354 interferon kappa-like	K05414 IFNA; interferon alpha 
C    121350454 interferon-like	K05415 IFNB; interferon beta 
C    121350455 interferon-like	K05415 IFNB; interferon beta 
C    121352566 IFNG; interferon gamma	K04687 IFNG; interferon gamma 
B  CSF and other factors
C    121365460 CSF1; macrophage colony-stimulating factor 1 isoform X1	K05453 CSF1; macrophage colony-stimulating factor 1 
C    121351176 CSF3; granulocyte colony-stimulating factor	K05423 CSF3; granulocyte colony-stimulating factor 
C    121350506 somatotropin	K05438 GH; growth hormone 
C    121353429 somatotropin-like	K05438 GH; growth hormone 
C    121353865 THPO; thrombopoietin	K06854 THPO; thrombopoietin 
C    121365085 LIF; leukemia inhibitory factor isoform X1	K05419 LIF; leukemia inhibitory factor 
C    121352347 CNTF; ciliary neurotrophic factor	K05420 CNTF; ciliary neurotrophic factor 
C    121355193 CLCF1; cardiotrophin-like cytokine factor 1	K05421 CLCF1; cardiotrophin-like cytokine factor 1 
B  Chemokines
C    121361694 C-C motif chemokine 13-like	K05514 CCL1; C-C motif chemokine 1 
C    121362947 C-C motif chemokine 4 homolog	K12964 CCL4; C-C motif chemokine 4 
C    121362949 C-C motif chemokine 4 homolog	K12964 CCL4; C-C motif chemokine 4 
C    121362948 C-C motif chemokine 5-like	K12499 CCL5; C-C motif chemokine 5 
C    121365757 C-C motif chemokine 3-like	K21092 CCL14; C-C motif chemokine 14 
C    121348885 C-C motif chemokine 3-like	K21083 CCL17; C-C motif chemokine 17 
C    121348923 C-C motif chemokine 5-like	K21083 CCL17; C-C motif chemokine 17 
C    121354254 C-C motif chemokine 19-like	K05512 CCL19; C-C motif chemokine 19 
C    121357971 CCL20; C-C motif chemokine 20	K14625 CCL20; C-C motif chemokine 20 
C    121354250 C-C motif chemokine 21-like	K16062 CCL21; C-C motif chemokine 21 
C    121349335 interleukin-8 isoform X1	K10030 IL8; interleukin 8 
C    121349341 interleukin-8-like	K10030 IL8; interleukin 8 
C    121349342 interleukin-8-like	K10030 IL8; interleukin 8 
C    121350161 CXCL12; stromal cell-derived factor 1 isoform X1	K10031 CXCL12; C-X-C motif chemokine 12 
C    121349310 C-X-C motif chemokine 9-like	K10032 CXCL13; C-X-C motif chemokine 13 
C    121349312 C-X-C motif chemokine 6-like	K10032 CXCL13; C-X-C motif chemokine 13 
C    121349315 interleukin-8-like	K10032 CXCL13; C-X-C motif chemokine 13 
C    121361370 CXCL14; C-X-C motif chemokine 14	K10033 CXCL14; C-X-C motif chemokine 14 
C    121348939 CX3CL1; fractalkine	K05508 CX3CL1; C-X3-C motif chemokine 1 
C    121351655 lymphotactin-like	K05507 XCL; C motif chemokine 
C    121351969 PROK2; prokineticin-2	K24191 PROK; prokineticin 
C    121348564 CYTL1; cytokine-like protein 1	K25418 CYTL1; cytokine-like protein 1 
B  Tumor necrosis fators
C    121348557 tumor necrosis factor-like	K03156 TNF; tumor necrosis factor superfamily, member 2 
C    121359745 TNFSF4; tumor necrosis factor ligand superfamily member 4	K05469 TNFSF4; tumor necrosis factor ligand superfamily member 4 
C    121349131 CD40LG; CD40 ligand	K03161 TNFSF5; tumor necrosis factor ligand superfamily member 5 
C    121359744 FASLG; tumor necrosis factor ligand superfamily member 6	K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6 
C    121357490 TNFSF8; tumor necrosis factor ligand superfamily member 8	K05471 TNFSF8; tumor necrosis factor ligand superfamily member 8 
C    121353789 TNFSF10; tumor necrosis factor ligand superfamily member 10	K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10 
C    121353320 TNFSF11; tumor necrosis factor ligand superfamily member 11	K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11 
C    121354121 TNFSF13B; tumor necrosis factor ligand superfamily member 13B	K05476 TNFSF13B; tumor necrosis factor ligand superfamily member 13B 
C    121357491 TNFSF15; tumor necrosis factor ligand superfamily member 15	K05478 TNFSF15; tumor necrosis factor ligand superfamily member 15 
C    121363189 EDA; ectodysplasin-A	K05480 EDA; ectodysplasin-A 
B  Transforming growth factors (RSTK binding)
C    121358714 TGFB2; transforming growth factor beta-2 proprotein	K13376 TGFB2; transforming growth factor beta-2 
C    121355988 TGFB3; transforming growth factor beta-3 proprotein	K13377 TGFB3; transforming growth factor beta-3 
C    121366000 BMP1; bone morphogenetic protein 1 isoform X1	K05502 BMP1; bone morphogenetic protein 1 [EC:3.4.24.19] 
C    121350125 bone morphogenetic protein 2-like	K21283 BMP2; bone morphogenetic protein 2 
C    121357049 BMP2; bone morphogenetic protein 2	K21283 BMP2; bone morphogenetic protein 2 
C    121349352 BMP3; bone morphogenetic protein 3 isoform X1	K05496 BMP3; bone morphogenetic protein 3 
C    121354039 BMP4; bone morphogenetic protein 4 isoform X1	K04662 BMP4; bone morphogenetic protein 4 
C    121358894 BMP5; bone morphogenetic protein 5 isoform X1	K04663 BMP5; bone morphogenetic protein 5 
C    121357758 BMP6; bone morphogenetic protein 6	K16620 BMP6; bone morphogenetic protein 6 
C    121359457 BMP7; bone morphogenetic protein 7	K16621 BMP7; bone morphogenetic protein 7 
C    121349946 bone morphogenetic protein 8B-like	K16622 BMP8; bone morphogenetic protein 8 
C    121359118 BMP10; bone morphogenetic protein 10	K22670 BMP10; bone morphogenetic protein 10 
C    121362868 BMP15; bone morphogenetic protein 15	K05498 BMP15; bone morphogenetic protein 15 
C    121352672 GDF1; embryonic growth/differentiation factor 1	K05495 GDF1; growth differentiation factor 1 
C    121350274 GDF2; growth/differentiation factor 2	K05503 GDF2; growth differentiation factor 2 
C    121365915 GDF5; growth/differentiation factor 5	K04664 GDF5; growth differentiation factor 5 
C    121355406 GDF6; growth/differentiation factor 6	K20012 GDF6; growth differentiation factor 6 
C    121360762 GDF7; growth/differentiation factor 7	K20013 GDF7; growth differentiation factor 7 
C    121364384 MSTN; growth/differentiation factor 8	K05497 MSTN; growth differentiation factor 8 
C    121365584 GDF9; growth/differentiation factor 9	K22673 GDF9; growth differentiation factor 9 
C    121350250 GDF10; growth/differentiation factor 10	K22674 GDF10; growth differentiation factor 10 
C    121359430 GDF11; growth/differentiation factor 11	K22679 GDF11; growth differentiation factor 11 
C    121352692 GDF15; growth/differentiation factor 15	K05504 GDF15; growth differentiation factor 15 
C    121360001 NODAL; nodal homolog	K04666 NODAL; nodal 
C    121356461 INHA; inhibin alpha chain	K05500 INHA; inhibin, alpha 
C    121353070 INHBA; inhibin beta A chain isoform X1	K04667 INHBA; inhibin beta A chain 
C    121356660 INHBB; inhibin beta B chain	K22687 INHBB; inhibin beta B chain 
C    121357472 inhibin beta C chain-like	K22688 INHBC; inhibin beta C chain 
C    121357475 inhibin beta C chain-like	K22689 INHBE; inhibin beta E chain 
C    121353355 AMH; muellerian-inhibiting factor isoform X1	K04665 AMH; anti-mullerian hormone 
C    121357085 left-right determination factor 2-like	K04668 LEFTY; left-right determination factor 
B  Growth factors (RTK binding)
C    121350738 PDGFA; platelet-derived growth factor subunit A isoform X1	K04359 PDGFA; platelet-derived growth factor subunit A 
C    121361210 PDGFB; platelet-derived growth factor subunit B	K17386 PDGFB; platelet-derived growth factor subunit B 
C    121360372 PDGFC; platelet-derived growth factor C	K05450 PDGFC_D; platelet derived growth factor C/D 
C    121364229 PDGFD; platelet-derived growth factor D isoform X1	K05450 PDGFC_D; platelet derived growth factor C/D 
C    121358564 VEGFA; vascular endothelial growth factor A isoform X1	K05448 VEGFA; vascular endothelial growth factor A 
C    121356236 VEGFD; vascular endothelial growth factor D	K05449 VEGFC_D; vascular endothelial growth factor C/D 
C    121360382 VEGFC; vascular endothelial growth factor C	K05449 VEGFC_D; vascular endothelial growth factor C/D 
C    121356054 PGF; placenta growth factor isoform X1	K16859 PGF; placenta growth factor 
C    121349758 NGF; beta-nerve growth factor	K02582 NGFB; nerve growth factor, beta 
C    121349673 NTF3; neurotrophin-3 isoform X1	K04356 NTF3; neurotrophin 3 
C    121363021 BDNF; brain-derived neurotrophic factor isoform X1	K04355 BDNF; brain-derived neurotrophic factor 
C    121356171 GDNF; glial cell line-derived neurotrophic factor	K05452 GDNF; glial cell derived neurotrophic factor 
C    121352707 NRTN; neurturin isoform X1	K25414 NRTN; neurturin 
C    121362163 ARTN; artemin isoform X1	K25415 ARTN; artemin 
C    121365607 FGF1; fibroblast growth factor 1 isoform X1	K18496 FGF1; fibroblast growth factor 1 
C    121361519 FGF2; fibroblast growth factor 2	K18497 FGF2; fibroblast growth factor 2 
C    121349098 FGF3; fibroblast growth factor 3	K04358 FGF; fibroblast growth factor 
C    121349099 FGF4; fibroblast growth factor 4	K04358 FGF; fibroblast growth factor 
C    121349333 FGF5; fibroblast growth factor 5 isoform X1	K04358 FGF; fibroblast growth factor 
C    121350241 FGF8; fibroblast growth factor 8 isoform X1	K04358 FGF; fibroblast growth factor 
C    121354474 FGF7; fibroblast growth factor 7 isoform X1	K04358 FGF; fibroblast growth factor 
C    121355098 FGF18; fibroblast growth factor 18 isoform X1	K04358 FGF; fibroblast growth factor 
C    121360303 FGF20; fibroblast growth factor 20	K04358 FGF; fibroblast growth factor 
C    121360635 FGF22; fibroblast growth factor 22 isoform X1	K04358 FGF; fibroblast growth factor 
C    121362807 FGF16; fibroblast growth factor 16	K04358 FGF; fibroblast growth factor 
C    121364235 FGF9; fibroblast growth factor 9	K04358 FGF; fibroblast growth factor 
C    121364332 FGF6; fibroblast growth factor 6	K04358 FGF; fibroblast growth factor 
C    121365279 FGF10; fibroblast growth factor 10	K04358 FGF; fibroblast growth factor 
C    121349122 FGF13; fibroblast growth factor 13 isoform X1	K22413 FGF11_12_13; fibroblast growth factor 11/12/13 
C    121353722 FGF12; fibroblast growth factor 12 isoform X1	K22413 FGF11_12_13; fibroblast growth factor 11/12/13 
C    121359387 FGF14; fibroblast growth factor 14 isoform X1	K23920 FGF14; fibroblast growth factor 14 
C    121349094 FGF19; fibroblast growth factor 19	K22603 FGF19; fibroblast growth factor 19 
C    121364344 FGF23; fibroblast growth factor 23	K22428 FGF23; fibroblast growth factor 23 
C    121355394 NRG1; pro-neuregulin-1, membrane-bound isoform isoform X1	K05455 NRG1; neuregulin 1 
C    121364615 NRG2; pro-neuregulin-2, membrane-bound isoform	K05456 NRG2; neuregulin 2 
C    121357423 NRG3; pro-neuregulin-3, membrane-bound isoform	K05457 NRG3; neuregulin 3 
C    121365489 NRG4; pro-neuregulin-4, membrane-bound isoform isoform X1	K05458 NRG4; neuregulin 4 
C    121363553 IGF1; insulin-like growth factor I	K05459 IGF1; insulin-like growth factor 1 
C    121361011 IGF2; insulin-like growth factor II	K13769 IGF2; insulin-like growth factor 2 
C    121357407 HGF; hepatocyte growth factor	K05460 HGF; hepatocyte growth factor 
C    121360365 EGF; pro-epidermal growth factor	K04357 EGF; epidermal growth factor 
C    121353986 TGFA; protransforming growth factor alpha	K08774 TGFA; transforming growth factor, alpha 
C    121349322 EREG; proepiregulin	K09784 EREG; epiregulin 
C    121349336 AREG; amphiregulin	K09782 AREG; amphiregulin 
C    121357229 KITLG; kit ligand isoform X1	K05461 KITLG; KIT ligand 
C    121352122 EFNA5; ephrin-A5	K05462 EFNA; ephrin-A 
C    121352155 EFNA3; ephrin-A3 isoform X1	K05462 EFNA; ephrin-A 
C    121352157 EFNA1; ephrin-A1	K05462 EFNA; ephrin-A 
C    121352177 uncharacterized protein LOC121352177	K05462 EFNA; ephrin-A 
C    121361174 EFNA2; ephrin-A2	K05462 EFNA; ephrin-A 
C    121354154 EFNB2; ephrin-B2	K05463 EFNB; ephrin-B 
C    121363038 EFNB1; ephrin-B1	K05463 EFNB; ephrin-B 
C    121352628 GAS6; growth arrest-specific protein 6	K05464 GAS6; growth arrest-specific 6 
C    121355399 ANGPT1; angiopoietin-1	K05465 ANGPT1; angiopoietin 1 
C    121358907 ANGPT2; angiopoietin-2 isoform X1	K05466 ANGPT2; angiopoietin 2 
C    121348573 ANGPT4; angiopoietin-4	K05467 ANGPT4; angiopoietin 4 
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A<b>Neuropeptides</b>
B  GPCR binding
C    121354205 AGT; angiotensinogen	K09821 AGT; angiotensinogen 
C    121353759 KNG1; kininogen-1 isoform X1	K03898 KNG; kininogen 
C    121357218 NTS; neurotensin/neuromedin N	K05235 NTS; neurotensin 
C    121354446 NMB; neuromedin-B isoform X1	K05223 NMB; neuromedin B 
C    121356130 gastrin-releasing peptide	K05224 GRP; gastrin-releasing peptide 
C    121353040 CCK; cholecystokinin	K05226 CCK; cholecystokinin 
C    121357850 EDN1; endothelin-1	K16366 EDN1; endothelin-1 
C    121360031 EDN2; endothelin-2	K16367 EDN2; endothelin-2 
C    121359564 EDN3; endothelin-3	K05227 EDN3; endothelin-3 
C    121360984 GAL; galanin peptides	K05244 GAL; galanin 
C    121352107 SPX; spexin	K25694 SPX; spexin 
C    121353582 promotilin-like isoform X1	K05265 MLN; motilin 
C    121348729 NMU; neuromedin-U	K05249 NMU; neuromedin U 
C    121354066 NMS; neuromedin-S	K25690 NMS; neuromedin S 
C    121353054 NPVF; pro-FMRFamide-related neuropeptide VF	K25692 NPVF; pro-FMRFamide-related neuropeptide VF 
C    121350373 NPS; neuropeptide S	K25691 NPS; neuropeptide S 
C    121353032 NPY; pro-neuropeptide Y	K05232 NPY; neuropeptide Y 
C    121352452 peptide YY-like	K05233 PYY; peptide YY 
C    121355275 neuropeptide W-like	K23141 NPW; neuropeptide W 
C    121365254 POMC; pro-opiomelanocortin	K05228 POMC; proopiomelanocortin 
C    121356847 PENK; proenkephalin-A	K18832 PENK; proenkephalin A 
C    121348606 PDYN; proenkephalin-B isoform X1	K15840 PDYN; proenkephalin B (prodynorphin) 
C    121360779 PNOC; prepronociceptin	K25696 PNOC; prepronociceptin 
C    121357678 orexigenic neuropeptide QRFP	K25693 QRFP; orexigenic neuropeptide QRFP 
C    121364710 neurophysin 1-like	K05243 OXT; oxytocin-neurophysin 1 
C    121353770 SST; somatostatin	K05237 SST; somatostatin 
C    121353036 TAC1; protachykinin-1 isoform X1	K05239 TAC1; tachykinin 1 
C    121358460 UTS2; urotensin-2	K05248 UTS2; urotensin 2 
C    121353774 UTS2B; urotensin-2B	K24267 UTS2B; urotensin-2B 
C    121364709 vasotocin-neurophysin VT	K05242 AVP; arginine vasopressin 
C    121353219 PRLH; prolactin-releasing peptide	K05269 PRH; prolactin-releasing peptide 
C    121355997 CHGA; chromogranin-A	K19990 CHGA; chromogranin-A 
C    121358570 CHGB; secretogranin-1 isoform X1	K19991 CHGB; chromogranin-B 
C    121357938 SCG2; secretogranin-2	K25732 SCG2; secretogranin-2 
C    121354570 SCG3; secretogranin-3 isoform X1	K25733 SCG3; secretogranin-3 
C    121365999 GNRH1; progonadoliberin-1	K05252 GNRH; gonadotropin-releasing hormone 
C    121352043 TRH; thyrotropin releasing hormone	K05253 TRH; thyrotropin-releasing hormone 
C    121363685 relaxin-3-like	K22000 RLN3; relaxin 3 
C    121362078 INSL5; insulin-like peptide INSL5	K22001 INSL5; insulin-like 5 
C    121363543 PMCH; pro-MCH	K05229 PMCH; pro-melanin-concentrating hormone 
C    121351136 gastrin/cholecystokinin-like peptide isoform X1	K13768 GAST; gastrin 
C    121360975 CALCB; calcitonin gene-related peptide 2 isoform X1	K12332 CALC; calcitonin 
C    121352063 ADM; pro-adrenomedullin	K12333 ADM; adrenomedullin 
C    121355089 ADM2; protein ADM2	K25343 ADM2; adrenomedullin-2 
C    121362672 islet amyloid polypeptide	K08039 IAPP; islet amyloid polypeptide 
C    121348625 corticoliberin-like	K05256 CRH; corticotropin-releasing hormone 
C    121356863 CRH; corticoliberin	K05256 CRH; corticotropin-releasing hormone 
C    121355677 UCN; urocortin	K23142 UCN; urocortin 
C    121352551 LOW QUALITY PROTEIN: urocortin-3-like	K05257 UCN2_3; urocortin 2/3 
C    121355714 UCN3; urocortin-3	K05257 UCN2_3; urocortin 2/3 
C    121356521 GCG; pro-glucagon	K05259 GCG; glucagon 
C    121363528 PTH; parathyroid hormone	K05261 PTH; parathyroid hormone 
C    121359078 ADCYAP1; pituitary adenylate cyclase-activating polypeptide isoform X1	K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide 
C    121354866 VIP peptides isoform X1	K05264 VIP; vasoactive intestinal peptide 
C    121363560 PTHLH; parathyroid hormone-related protein	K22608 PTHLH; parathyroid hormone-related hormone 
C    121360522 CGA; glycoprotein hormones alpha chain	K08522 CGA; glycoprotein hormones alpha chain 
C    121363047 FSHB; follitropin subunit beta	K05250 FSHB; follitropin subunit beta 
C    121354234 lutropin subunit beta-like	K08521 LHB; lutropin subunit beta 
C    121349779 TSHB; thyrotropin subunit beta	K05251 TSHB; thyrotropin subunit beta 
B  Unclassified
C    121358380 natriuretic peptides A	K12334 NPPA; natriuretic peptide A 
C    121351577 C-type natriuretic peptide-like	K12336 NPPC; natriuretic peptide C 
C    121353667 NPPC; C-type natriuretic peptide	K12336 NPPC; natriuretic peptide C 
C    121353039 NXPH1; neurexophilin-1	K16656 NXPH1; neurexophilin-1 
C    121356771 NXPH2; neurexophilin-2	K16657 NXPH2; neurexophilin-2 
C    121352443 NXPH3; neurexophilin-3	K16658 NXPH3; neurexophilin-3 
C    121357474 NXPH4; neurexophilin-4	K25711 NXPH4; neurexophilin-4 
C    121361012 INS; insulin	K04526 INS; insulin 
C    121348668 leptin-like	K05424 LEP; leptin 
C    121352576 prolactin-like	K05439 PRL; prolactin 
C    121357786 PRL; prolactin	K05439 PRL; prolactin 
C    121363785 CARTPT; LOW QUALITY PROTEIN: cocaine- and amphetamine-regulated transcript protein	K25453 CARTPT; cocaine- and amphetamine-regulated transcript protein 
C    121348765 agouti-related protein	K05231 AGRP; agouti related protein 
C    121356727 DBI; acyl-CoA-binding protein	K08762 DBI; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) 
C    121348997 CBLN1; cerebellin-1	K24235 CBLN; cerebellin 
C    121359521 CBLN4; cerebellin-4	K24235 CBLN; cerebellin 
C    121362912 CBLN2; cerebellin-2	K24235 CBLN; cerebellin 
C    121364084 ADIPOQ; LOW QUALITY PROTEIN: adiponectin	K07296 ADIPOQ; adiponectin 
C    121357363 NAMPT; nicotinamide phosphoribosyltransferase isoform X1	K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12] 
C    121360986 NUCB2; nucleobindin-2	K20371 NUCB; nucleobindin 
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#Last updated: April 23, 2025