+F Repair protein KO
#
DNA Repair and Recombination Proteins - Polymorphospora rubra
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Prubr_25170 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Prubr_34520 putative methylated-DNA:protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Prubr_50800 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Prubr_23060 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Prubr_15350 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Prubr_49590 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Prubr_29640 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E Prubr_20420 helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Prubr_57680 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_60160 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_70990 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_05190 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_15050 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_15060 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_23940 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_26190 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_33850 mutT; 7,8-dihydro-8-oxoguanine triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_34630 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_51560 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_42010 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Prubr_25170 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Prubr_34520 putative methylated-DNA:protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Prubr_50800 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Prubr_23060 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Prubr_08550 hypothetical protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D Prubr_29110 alkB; alkylated DNA repair protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E Prubr_15350 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Prubr_14300 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Prubr_41280 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Prubr_34530 DNA-3-methyladenine glycosylase K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Prubr_49590 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Prubr_32120 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Prubr_26130 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Prubr_39680 hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Prubr_36140 nei_1; endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E Prubr_40990 nei_2; putative endonuclease 8 2 K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E Prubr_29640 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Prubr_45560 hypothetical protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Prubr_47350 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Prubr_04300 nfo_1; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E Prubr_25240 nfo_2; deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E Prubr_13560 nfi; endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
E Prubr_70710 ligA2; DNA ligase 2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Prubr_38790 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Prubr_02980 DNA polymerase (POL I) K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Prubr_02490 uvrA_1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E Prubr_02900 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E Prubr_02470 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E Prubr_14900 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Prubr_34960 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Prubr_35120 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Prubr_02980 DNA polymerase (POL I) K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Prubr_70710 ligA2; DNA ligase 2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Prubr_38790 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Prubr_16130 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Prubr_16120 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Prubr_15740 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Prubr_49060 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Prubr_14470 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E Prubr_34420 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Prubr_34410 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Prubr_19950 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Prubr_60710 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Prubr_24910 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Prubr_08330 holA; hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Prubr_20690 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Prubr_70460 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Prubr_04680 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Prubr_06870 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Prubr_29140 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Prubr_70710 ligA2; DNA ligase 2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Prubr_38790 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Prubr_14900 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Prubr_34960 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Prubr_35120 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Prubr_09440 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E Prubr_11480 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Prubr_70020 recD2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Prubr_41310 recA; protein RecA K03553 recA; recombination protein RecA
E Prubr_48580 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Prubr_48590 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Prubr_48570 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Prubr_49090 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Prubr_42450 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Prubr_42460 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Prubr_41310 recA; protein RecA K03553 recA; recombination protein RecA
E Prubr_30220 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Prubr_24890 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Prubr_39600 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Prubr_08000 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Prubr_29160 recR; recombination protein RecR K06187 recR; recombination protein RecR
E Prubr_49690 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Prubr_48580 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Prubr_48590 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Prubr_48570 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E Prubr_42450 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Prubr_42460 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E Prubr_20440 hypothetical protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E Prubr_20450 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Prubr_66740 gyrA_2; DNA topoisomerase (ATP-hydrolyzing) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Prubr_24850 gyrA_1; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Prubr_66750 gyrB_2; DNA topoisomerase (ATP-hydrolyzing) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Prubr_24860 gyrB_1; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Prubr_20750 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F Prubr_48110 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Prubr_39420 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Prubr_08000 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Prubr_29160 recR; recombination protein RecR K06187 recR; recombination protein RecR
F Prubr_70710 ligA2; DNA ligase 2 K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F Prubr_38790 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Prubr_06610 recQ_1; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Prubr_16730 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Prubr_48130 recQ_2; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Prubr_02490 uvrA_1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F Prubr_02900 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Prubr_04050 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D Prubr_41310 recA; protein RecA K03553 recA; recombination protein RecA
D Prubr_41510 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D Prubr_49690 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Prubr_04110 hypothetical protein K14161 imuB; protein ImuB
D Prubr_04090 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D Prubr_09440 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D Prubr_41320 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Prubr_31150 hypothetical protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Prubr_41120 lhr; DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Prubr_57680 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_60160 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_70990 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_05190 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_15050 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_15060 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_23940 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_26190 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_33850 mutT; 7,8-dihydro-8-oxoguanine triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_34630 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_51560 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Prubr_39440 putative hydrolase MutT/NUDIX K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D Prubr_18110 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D Prubr_49770 ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D Prubr_42010 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Prubr_41550 nrdA; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Prubr_57010 ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Prubr_57020 nrdB; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D Prubr_40530 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024