+F Repair protein KO
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DNA Repair and Recombination Proteins - Mollisia scopiformis
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LY89DRAFT_654100 methylated-DNA--cysteine S-met K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LY89DRAFT_679953 uncharacterized protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LY89DRAFT_679568 uncharacterized protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LY89DRAFT_605421 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LY89DRAFT_565894 DNA glycosylase K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E LY89DRAFT_776252 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E LY89DRAFT_684322 DNA glycosylase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LY89DRAFT_696138 apurinic/apyrimidinic endonuclease-like protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E LY89DRAFT_691728 DNase I-like protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F LY89DRAFT_740574 uncharacterized protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F LY89DRAFT_619491 DNA polymerase-like protein subunit delta-2 K02328 POLD2; DNA polymerase delta subunit 2
F LY89DRAFT_790120 uncharacterized protein K03504 POLD3; DNA polymerase delta subunit 3
F LY89DRAFT_679938 uncharacterized protein K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F LY89DRAFT_787183 DUF1744-domain-containing protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F LY89DRAFT_782999 uncharacterized protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F LY89DRAFT_610518 histone-fold-containing protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E LY89DRAFT_607274 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E LY89DRAFT_686547 flap endonuclease-like protein 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E LY89DRAFT_493340 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E LY89DRAFT_585461 tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E LY89DRAFT_721198 phospholipase D/nuclease K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E LY89DRAFT_656717 HIT-like protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E LY89DRAFT_653805 PNK3P-domain-containing protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E LY89DRAFT_707348 PARP-domain-containing protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F LY89DRAFT_204884 Rad4-domain-containing protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F LY89DRAFT_685449 Rad4-domain-containing protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F LY89DRAFT_623137 UV excision repair protein Rad23 K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F LY89DRAFT_688943 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F LY89DRAFT_597120 Cullin-domain-containing protein K10609 CUL4; cullin 4
F LY89DRAFT_646785 uncharacterized protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F LY89DRAFT_352368 DNA repair protein-like protein Rad7 K15082 RAD7; DNA repair protein RAD7
F LY89DRAFT_711924 uncharacterized protein K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F LY89DRAFT_16699 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F LY89DRAFT_683984 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F LY89DRAFT_155990 RNA polymerase II subunit 3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F LY89DRAFT_595077 uncharacterized protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F LY89DRAFT_616916 RPB5 subunit of DNA-directed RNA polymerase K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F LY89DRAFT_681554 RNA polymerase Rpb6 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F LY89DRAFT_599800 uncharacterized protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F LY89DRAFT_661535 DNA-directed RNA polymerases and 3 polypeptide K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F LY89DRAFT_683074 DNA-directed RNA polymerase-like protein II subunit rpb9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F LY89DRAFT_604672 putative DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F LY89DRAFT_686261 RBP11-like subunits of RNA polymerase K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F LY89DRAFT_345210 DNA directed RNA polymerase K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F LY89DRAFT_688943 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F LY89DRAFT_597120 Cullin-domain-containing protein K10609 CUL4; cullin 4
F LY89DRAFT_646785 uncharacterized protein K10610 DDB1; DNA damage-binding protein 1
F LY89DRAFT_688371 WD40 repeat-like protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F LY89DRAFT_682766 uncharacterized protein K10841 ERCC6; DNA excision repair protein ERCC-6
F LY89DRAFT_682830 Elf1-domain-containing protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E LY89DRAFT_718388 DNA repair helicase rad25 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E LY89DRAFT_703743 DNA repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E LY89DRAFT_750435 uncharacterized protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E LY89DRAFT_629844 TFIIH basal transcription factor complex, subunit SSL1 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E LY89DRAFT_652593 transcription factor Tfb4 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E LY89DRAFT_452072 transcription factor Tfb2 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E LY89DRAFT_684331 RNA polymerase II transcription factor B subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E LY89DRAFT_588514 Pkinase-domain-containing protein K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E LY89DRAFT_681523 cyclin-like protein K06634 CCNH; cyclin H
E LY89DRAFT_690016 RNA polymerase II transcription factor-like protein B subunit 3 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E LY89DRAFT_688416 replication factor-a protein K07466 RFA1; replication factor A1
E LY89DRAFT_782492 replication protein A, subunit RPA32 K10739 RFA2; replication factor A2
E LY89DRAFT_391103 replication factor A protein 3 K10740 RPA3; replication factor A3
D Other NER factors
E LY89DRAFT_540787 DNA repair protein K10847 XPA; DNA-repair protein complementing XP-A cells
E LY89DRAFT_640555 uncharacterized protein K10849 ERCC1; DNA excision repair protein ERCC-1
E LY89DRAFT_777280 DNA repair protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E LY89DRAFT_683768 PIN domain-like protein K10846 ERCC5; DNA excision repair protein ERCC-5
E LY89DRAFT_493340 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E LY89DRAFT_689026 uncharacterized protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E LY89DRAFT_613538 Cullin-domain-containing protein K03869 CUL3; cullin 3
E LY89DRAFT_663595 putative Elongin-C K03872 ELOC; elongin-C
E LY89DRAFT_549259 uncharacterized protein K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LY89DRAFT_787089 DNA mismatch repair protein msh-2 K08735 MSH2; DNA mismatch repair protein MSH2
E LY89DRAFT_636859 DNA mismatch repair protein msh3 K08736 MSH3; DNA mismatch repair protein MSH3
E LY89DRAFT_643546 DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E LY89DRAFT_631908 DNA mismatch repair protein MutL K08734 MLH1; DNA mismatch repair protein MLH1
E LY89DRAFT_678911 DNA mismatch repair protein MutL K10858 PMS2; DNA mismatch repair protein PMS2
E LY89DRAFT_743715 uncharacterized protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E LY89DRAFT_740574 uncharacterized protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E LY89DRAFT_619491 DNA polymerase-like protein subunit delta-2 K02328 POLD2; DNA polymerase delta subunit 2
E LY89DRAFT_790120 uncharacterized protein K03504 POLD3; DNA polymerase delta subunit 3
E LY89DRAFT_679938 uncharacterized protein K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E LY89DRAFT_688416 replication factor-a protein K07466 RFA1; replication factor A1
E LY89DRAFT_782492 replication protein A, subunit RPA32 K10739 RFA2; replication factor A2
E LY89DRAFT_391103 replication factor A protein 3 K10740 RPA3; replication factor A3
D RFC (replication factor C)
E LY89DRAFT_684333 DNA replication factor C, large subunit K10754 RFC1; replication factor C subunit 1
E LY89DRAFT_679259 P-loop containing nucleoside triphosphate hydrolase protein K10755 RFC2_4; replication factor C subunit 2/4
E LY89DRAFT_611996 P-loop containing nucleoside triphosphate hydrolase protein K10755 RFC2_4; replication factor C subunit 2/4
E LY89DRAFT_788408 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
E LY89DRAFT_721343 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E LY89DRAFT_607274 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E LY89DRAFT_619648 uncharacterized protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E LY89DRAFT_493340 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E LY89DRAFT_588902 WD40 repeat-like protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E LY89DRAFT_605531 DNA repair exonuclease K10865 MRE11; double-strand break repair protein MRE11
E LY89DRAFT_706435 uncharacterized protein K10867 NBN; nibrin
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E LY89DRAFT_605531 DNA repair exonuclease K10865 MRE11; double-strand break repair protein MRE11
E LY89DRAFT_706435 uncharacterized protein K10867 NBN; nibrin
D BRCA complex
D RecA family proteins
E LY89DRAFT_788877 P-loop containing nucleoside triphosphate hydrolase protein K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E LY89DRAFT_624575 uncharacterized protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E LY89DRAFT_689317 uncharacterized protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E LY89DRAFT_609528 uncharacterized protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E LY89DRAFT_607616 uncharacterized protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E LY89DRAFT_607616 uncharacterized protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E LY89DRAFT_421355 DNA topoisomerase-like protein III K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E LY89DRAFT_563204 uncharacterized protein K15364 NCE4; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E LY89DRAFT_688416 replication factor-a protein K07466 RFA1; replication factor A1
E LY89DRAFT_782492 replication protein A, subunit RPA32 K10739 RFA2; replication factor A2
E LY89DRAFT_391103 replication factor A protein 3 K10740 RPA3; replication factor A3
D Protein phosphatase 4
E LY89DRAFT_137694 DUF625-domain-containing protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E LY89DRAFT_713948 P-loop containing nucleoside triphosphate hydrolase protein K22803 SMC5; structural maintenance of chromosomes protein 5
E LY89DRAFT_595663 putative structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E LY89DRAFT_660755 uncharacterized protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E LY89DRAFT_652687 uncharacterized protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E LY89DRAFT_726623 Nse4-domain-containing protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E LY89DRAFT_727761 uncharacterized protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E LY89DRAFT_691372 uncharacterized protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E LY89DRAFT_695016 uncharacterized protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E LY89DRAFT_788713 uncharacterized protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E LY89DRAFT_584753 uncharacterized protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E LY89DRAFT_621328 PIN domain-like protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E LY89DRAFT_783633 uncharacterized protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E LY89DRAFT_122575 AAA-domain-containing protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E LY89DRAFT_727386 WLM-domain-containing protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E LY89DRAFT_777398 WLM-domain-containing protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E LY89DRAFT_607135 P-loop containing nucleoside triphosphate hydrolase protein K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E LY89DRAFT_620587 ku70 protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E LY89DRAFT_715267 SPOC domain-like protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E LY89DRAFT_605531 DNA repair exonuclease K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E LY89DRAFT_638376 ATP-dependent DNA ligase K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E LY89DRAFT_695003 DNA polymerase lambda K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
E LY89DRAFT_602043 Nucleotidyltransferase K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
E LY89DRAFT_656717 HIT-like protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E LY89DRAFT_764166 uncharacterized protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E LY89DRAFT_539743 uncharacterized protein K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E LY89DRAFT_607616 uncharacterized protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E LY89DRAFT_421355 DNA topoisomerase-like protein III K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E LY89DRAFT_563204 uncharacterized protein K15364 NCE4; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E LY89DRAFT_633896 uncharacterized protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E LY89DRAFT_292418 uncharacterized protein K11137 TELO2; telomere length regulation protein
E LY89DRAFT_703753 WD repeat protein-like protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E LY89DRAFT_669779 uncharacterized protein K23314 WRAP53; telomerase Cajal body protein 1
E LY89DRAFT_687879 WD40 repeat-like protein K24752 WDR70; WD repeat-containing protein 70
E LY89DRAFT_346824 uncharacterized protein K24752 WDR70; WD repeat-containing protein 70
E LY89DRAFT_588902 WD40 repeat-like protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LY89DRAFT_281011 DNA/RNA polymerase K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D LY89DRAFT_781330 DNA/RNA polymerase K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D LY89DRAFT_643298 impB/mucB/samB family protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D LY89DRAFT_714252 DNA repair protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D LY89DRAFT_789805 uncharacterized protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D LY89DRAFT_685126 ubiquitin-conjugating enzyme E2 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D LY89DRAFT_790119 DNA repair protein rad18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D LY89DRAFT_608615 putative DNA repair protein rad-5 K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D LY89DRAFT_782638 putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D LY89DRAFT_675458 uncharacterized protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D LY89DRAFT_705497 UBC-like protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D LY89DRAFT_713764 ubiquitin-conjugating enzyme E2 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D LY89DRAFT_607274 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D LY89DRAFT_649201 uncharacterized protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D LY89DRAFT_233184 Rad9-domain-containing protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D LY89DRAFT_716527 cell cycle checkpoint protein-like protein K10903 HUS1; HUS1 checkpoint protein
D LY89DRAFT_326242 Rad1-domain-containing protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D LY89DRAFT_701849 Rad17-domain-containing protein K06662 HRAD17; cell cycle checkpoint protein
D LY89DRAFT_679259 P-loop containing nucleoside triphosphate hydrolase protein K10755 RFC2_4; replication factor C subunit 2/4
D LY89DRAFT_611996 P-loop containing nucleoside triphosphate hydrolase protein K10755 RFC2_4; replication factor C subunit 2/4
D LY89DRAFT_788408 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
D LY89DRAFT_721343 P-loop containing nucleoside triphosphate hydrolase protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D LY89DRAFT_326242 Rad1-domain-containing protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D LY89DRAFT_641737 timeless-domain-containing protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D LY89DRAFT_657627 Swi3-domain-containing protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D LY89DRAFT_647814 uncharacterized protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D LY89DRAFT_292418 uncharacterized protein K11137 TELO2; telomere length regulation protein
D LY89DRAFT_642001 uncharacterized protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D LY89DRAFT_598710 uncharacterized protein K23388 UBL4; ubiquitin-like protein 4
D LY89DRAFT_716448 DUF410-domain-containing protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D LY89DRAFT_598327 protein kinase-like protein rad3 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D LY89DRAFT_266352 phosphatidylinositol 3 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D LY89DRAFT_703354 serine/threonine-protein kinase-like protein chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D LY89DRAFT_714214 Pkinase-domain-containing protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D LY89DRAFT_582573 Rhodanese-like protein K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D LY89DRAFT_311691 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D LY89DRAFT_664392 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D LY89DRAFT_587047 kinase-like protein K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D LY89DRAFT_729804 uncharacterized protein K24664 FKH; forkhead protein FKH
D LY89DRAFT_588754 vacuolar protein sorting-associated protein-like protein VPS4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D LY89DRAFT_589105 AAA-domain-containing protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D LY89DRAFT_684185 uncharacterized protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D LY89DRAFT_706332 uncharacterized protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D LY89DRAFT_722955 DRMBL-domain-containing protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D LY89DRAFT_646003 uncharacterized protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
D LY89DRAFT_692244 S1/P1 nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
D LY89DRAFT_617209 S1/P1 nuclease-like protein K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D LY89DRAFT_673684 uncharacterized protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D LY89DRAFT_715041 Prp19-domain-containing protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D LY89DRAFT_617319 uncharacterized protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D LY89DRAFT_647590 uncharacterized protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D LY89DRAFT_730614 WD40 repeat-like protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D LY89DRAFT_574655 putative Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LY89DRAFT_692414 uncharacterized protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D LY89DRAFT_608592 uncharacterized protein K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LY89DRAFT_654100 methylated-DNA--cysteine S-met K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LY89DRAFT_679953 uncharacterized protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LY89DRAFT_679568 uncharacterized protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LY89DRAFT_605421 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LY89DRAFT_688485 HhH-GPD superfamily base excision DNA repair protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E LY89DRAFT_652724 putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LY89DRAFT_684322 DNA glycosylase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LY89DRAFT_682311 P-loop containing nucleoside triphosphate hydrolase protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E LY89DRAFT_682311 P-loop containing nucleoside triphosphate hydrolase protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D LY89DRAFT_574655 putative Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024