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Transfer RNA Biogenesis - Pseudomonas sp. Stari2
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D NH234_20185 ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D NH234_27135 multifunctional CCA addition/repair protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D NH234_11495 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D NH234_10735 gltX; (GenBank) glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D NH234_07050 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D NH234_25625 ileS; (GenBank) isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D NH234_26145 leuS; (GenBank) leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NH234_23755 metG; (GenBank) methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D NH234_19300 glutamine--tRNA ligase/YqeY domain fusion protein K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D NH234_02915 argS; (GenBank) arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D NH234_06315 lysS; (GenBank) lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NH234_23295 aspS; (GenBank) aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D NH234_22615 alaS; (GenBank) alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D NH234_11020 thrS; (GenBank) threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NH234_19030 serS; (GenBank) serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NH234_19295 cysS; (GenBank) cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D NH234_05960 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D NH234_24265 hisS; (GenBank) histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D NH234_11040 pheS; (GenBank) phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NH234_11045 pheT; (GenBank) phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D NH234_26920 tyrS; (GenBank) tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NH234_24765 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D NH234_02780 dtd; (GenBank) D-aminoacyl-tRNA deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D NH234_26965 histidine triad nucleotide-binding protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D NH234_28050 trmB; (GenBank) tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D NH234_06980 tsaA; (GenBank) tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D NH234_10830 truA; (GenBank) tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D NH234_04845 truB; (GenBank) tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D NH234_06655 truD; (GenBank) tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D NH234_20765 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D NH234_24325 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D NH234_01065 L-threonylcarbamoyladenylate synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D NH234_03520 miaA; (GenBank) tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D NH234_00945 mnmE; (GenBank) tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D NH234_00940 mnmG; (GenBank) tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D NH234_19925 selD; (GenBank) selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D NH234_02340 cysQ; (GenBank) 3'(2'),5'-bisphosphate nucleotidase CysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D NH234_00960 rnpA; (GenBank) ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D NH234_24680 rnpB; (GenBank) RNase P RNA component class A K01978 rnpB; RNase P catalytic RNA component
B 3'processing and CCA adding factors
C 3'processing factors
D NH234_23820 rnt; (GenBank) ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D NH234_00170 rph; (GenBank) ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D NH234_08235 rnd; (GenBank) ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D NH234_20185 ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D NH234_27135 multifunctional CCA addition/repair protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D NH234_11495 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D NH234_12305 thpR; (GenBank) RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
D NH234_25740 ettA; (GenBank) energy-dependent translational throttle protein EttA K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D NH234_26145 leuS; (GenBank) leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NH234_07050 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D NH234_26920 tyrS; (GenBank) tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NH234_24765 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D NH234_11020 thrS; (GenBank) threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NH234_25625 ileS; (GenBank) isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D NH234_06315 lysS; (GenBank) lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NH234_22615 alaS; (GenBank) alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D NH234_05960 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D NH234_23755 metG; (GenBank) methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D NH234_19030 serS; (GenBank) serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NH234_23295 aspS; (GenBank) aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NH234_01015 glyQ; (GenBank) glycine--tRNA ligase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D NH234_01010 glyS; (GenBank) glycine--tRNA ligase subunit beta K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D NH234_19295 cysS; (GenBank) cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D NH234_10735 gltX; (GenBank) glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D NH234_19300 glutamine--tRNA ligase/YqeY domain fusion protein K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D NH234_02915 argS; (GenBank) arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D NH234_11040 pheS; (GenBank) phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NH234_11045 pheT; (GenBank) phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D NH234_24265 hisS; (GenBank) histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D NH234_25370 gluQRS; (GenBank) tRNA glutamyl-Q(34) synthetase GluQRS K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D NH234_02780 dtd; (GenBank) D-aminoacyl-tRNA deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D NH234_23870 ybaK; (GenBank) Cys-tRNA(Pro) deacylase K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D NH234_01800 YbaK/EbsC family protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
D NH234_20240 dusA; (GenBank) tRNA dihydrouridine(20/20a) synthase DusA K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D NH234_03995 dusB; (GenBank) tRNA dihydrouridine synthase DusB K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D NH234_10775 tRNA-dihydrouridine synthase K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D NH234_26110 miaB; (GenBank) tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D NH234_20080 class I SAM-dependent methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D NH234_24175 cmoA; (GenBank) carboxy-S-adenosyl-L-methionine synthase CmoA K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D NH234_24180 cmoB; (GenBank) tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D NH234_04085 methyltransferase domain-containing protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D NH234_25855 trmA; (GenBank) tRNA (uridine(54)-C5)-methyltransferase TrmA K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D NH234_28050 trmB; (GenBank) tRNA (guanosine(46)-N7)-methyltransferase TrmB K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D NH234_06125 trmD; (GenBank) tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D NH234_00945 mnmE; (GenBank) tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D NH234_24340 trmJ; (GenBank) tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D NH234_17225 tRNA (adenine(22)-N(1))-methyltransferase TrmK K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]
D NH234_02610 tRNA (cytidine(34)-2'-O)-methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D NH234_06980 tsaA; (GenBank) tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D NH234_10830 truA; (GenBank) tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D NH234_04845 truB; (GenBank) tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D NH234_06655 truD; (GenBank) tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D NH234_09790 RluA family pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D NH234_21050 pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D NH234_19100 mnmA; (GenBank) tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D NH234_22410 ttcA; (GenBank) tRNA 2-thiocytidine(32) synthetase TtcA K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D NH234_08130 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D NH234_20560 tusA; (GenBank) sulfurtransferase TusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D NH234_19005 tusB; (GenBank) sulfurtransferase complex subunit TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D NH234_19000 tusC; (GenBank) sulfurtransferase complex subunit TusC K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D NH234_18995 tusD; (GenBank) sulfurtransferase complex subunit TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D NH234_19010 TusE/DsrC/DsvC family sulfur relay protein K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D NH234_24315 iscA; (GenBank) iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D NH234_20765 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D NH234_24325 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D NH234_08085 folate-binding protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D NH234_00940 mnmG; (GenBank) tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D NH234_03520 miaA; (GenBank) tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D NH234_18265 tRNA-(ms[2]io[6]A)-hydroxylase K06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]
D NH234_21735 mnmC; (GenBank) bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D NH234_24375 queA; (GenBank) tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D NH234_08800 queC; (GenBank) 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D NH234_23230 queC; (GenBank) 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D NH234_20030 queD; (GenBank) 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D NH234_23235 queE; (GenBank) 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D NH234_20385 queF; (GenBank) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D NH234_03495 queG; (GenBank) tRNA epoxyqueuosine(34) reductase QueG K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D NH234_19925 selD; (GenBank) selenide, water dikinase SelD K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D NH234_19920 mnmH; (GenBank) tRNA 2-selenouridine(34) synthase MnmH K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D NH234_24370 tgt; (GenBank) tRNA guanosine(34) transglycosylase Tgt K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D NH234_02650 thiI; (GenBank) tRNA 4-thiouridine(8) synthase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D NH234_06605 tilS; (GenBank) tRNA lysidine(34) synthetase TilS K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D NH234_06375 tsaB; (GenBank) tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D NH234_01065 L-threonylcarbamoyladenylate synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D NH234_27155 tsaD; (GenBank) tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D NH234_03505 tsaE; (GenBank) tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D NH234_06470 tcdA; (GenBank) tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C NH234_03580 rnr; (GenBank) ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C NH234_04855 pnp; (GenBank) polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025