+C Two-component system KO
#
Two-Component System - Pseudomonas sp. StFLB209
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C PSCI_1863 sensory box sensor histidine kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C PSCI_1864 phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
C PSCI_0410 sensor histidine kinase K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C PSCI_0411 transcriptional regulatory protein PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
B EnvZ-OmpR (osmotic stress response)
C PSCI_1422 osmolarity sensor protein EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C PSCI_1423 ompR; osmolarity response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C PSCI_0415 sensor histidine kinase K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C PSCI_0416 DNA-binding response regulator RstA K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C PSCI_0189 DNA-binding response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C PSCI_1308 sensory histidine kinase CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C PSCI_1309 DNA-binding response regulator CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C PSCI_0662 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PSCI_1755 heavy metal sensor signal transduction histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PSCI_3772 copS; copper sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PSCI_5105 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C PSCI_0661 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C PSCI_1754 winged helix family two component heavy metal response transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C PSCI_3773 two component heavy metal response transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C PSCI_5104 two component heavy metal response transcriptional regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
C PSCI_1393 integral membrane sensor signal transduction histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C PSCI_2992 signal transduction histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C PSCI_1392 two component transcriptional regulator, winged helix family K07666 qseB; two-component system, OmpR family, response regulator QseB
C PSCI_2991 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C PSCI_3959 sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C PSCI_3960 KDP operon transcriptional regulatory protein kdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C PSCI_3025 sensor histidine kinase TctE K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C PSCI_3024 DNA-binding response regulator TctD K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
C PSCI_5394 integral membrane sensor signal transduction histidine kinase K19609 pfeS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]
C PSCI_5393 two component transcriptional regulator, winged helix family K19610 pfeR; two-component system, OmpR family, response regulator PfeR
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C PSCI_1546 integral membrane sensor signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C PSCI_0679 DNA-binding response regulator GltR K02483 K02483; two-component system, OmpR family, response regulator
C PSCI_1545 mmfR; transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C PSCI_1594 two component transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C PSCI_2520 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C PSCI_3855 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C PSCI_5136 two component transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C PSCI_5242 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C PSCI_5439 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
#
ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C PSCI_0399 response regulator, sensor histidine kinase component GacS K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C PSCI_4025 gacA; DNA-binding response regulator GacA K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C PSCI_0091 sensory box histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C PSCI_3886 multi-sensor hybrid histidine kinase K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C PSCI_0484 LuxR response regulator receiver K07690 evgA; two-component system, NarL family, response regulator EvgA
C PSCI_3887 LuxR response regulator receiver K07690 evgA; two-component system, NarL family, response regulator EvgA
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
C PSCI_1105 sensory box histidine kinase K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]
C PSCI_1108 LuxR family DNA-binding response regulator K27077 pprB; two-component system, NarL family, response regulator PprB
B Unclassified
#
ASpo family
B KinABCDE-Spo0FA (sporulation control)
#
ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
#
ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C PSCI_1491 sensor histidine kinase FimS K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
C PSCI_1490 alginate biosynthesis regulatory protein AlgR K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B BtsS-BtsR (pyruvate reutilization)
B PyrS-PyrR (pyruvate reutilization)
B Unclassified
#
ANtrC family
B GlnL-GlnG (nitrogen regulation)
C PSCI_2154 sensor histidine kinase K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C PSCI_2153 nitrogen regulation protein K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C PSCI_0979 sigma-54-dependent DNA-binding response regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
C PSCI_1007 type IV pilus sensor protein PilS K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C PSCI_1008 type IV fimbriae expression regulatory protein pilR K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C PSCI_1936 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C PSCI_2964 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C PSCI_1935 sigma-54-dependent DNA-binding response regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C PSCI_2963 Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
C PSCI_1631 sensory box histidine kinase K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
C PSCI_1630 helix-turn-helix, Fis-type K11384 algB; two-component system, NtrC family, response regulator AlgB
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
#
ACheA family
B CheA-CheYBV (chemotaxis)
C PSCI_0210 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C PSCI_3497 CheW-like protein:ATP-binding region K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C PSCI_0208 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C PSCI_3495 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C PSCI_0215 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C PSCI_3498 chemotaxis-specific methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C PSCI_4313 protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C PSCI_0650 chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C PSCI_3439 chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C PSCI_5488 chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
C PSCI_2019 sensor histidine kinase/response regulator K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C PSCI_2015 response regulator receiver K02657 pilG; twitching motility two-component system response regulator PilG
C PSCI_2016 type IV pilus response regulator PilH K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
C PSCI_0077 sensor histidine kinase/response regulator K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
C PSCI_0075 response regulator WspR K11444 wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65]
C PSCI_0076 chemotaxis-specific methylesterase K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
B Cph1-Rcp1 (light response)
C PSCI_3367 bacteriophytochrome histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
C PSCI_5067 GAF sensor signal transduction histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
#
ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
#
ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
#
ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
#
AOther families
B FlrB-FlrC (polar flagellar synthesis)
C PSCI_3471 flagellar sensor histidine kinase FleS K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C PSCI_3472 sigma-54-dependent DNA-binding response regulator FleR K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
C PSCI_0508 sensor histidine kinase K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
C PSCI_0509 sigma-54-dependent DNA-binding response regulator K17061 aauR; two-component system, response regulator AauR
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C PSCI_2633 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C PSCI_2634 Fis family DNA-binding response regulator K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C PSCI_0315 sensor histidine kinase/response regulator K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
C PSCI_4903 sensor histidine kinase K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
C PSCI_3481 Hpt domain-containing protein K20976 hptB; histidine phosphotransfer protein HptB
C PSCI_3480 response regulator K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator
B PdtaS-PdtaR
B NasS-NasT
C PSCI_3879 nitrate transporter component K22067 nasS; two-component system, oxyanion-binding sensor
C PSCI_3878 response regulator receiver:ANTAR K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
C PSCI_2601 sensor histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS
C PSCI_2421 sensor histidine kinase/response regulator K20972 retS; two-component system, sensor histidine kinase RetS
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 8, 2024