+D Protein KO
#
Membrane Trafficking - Phaeodactylum tricornutum
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
D PHATRDRAFT_50498 hypothetical protein K28063 ESYT; extended synaptotagmin
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
C Phospholipases
D PHATRDRAFT_42683 PLC-delta; phospholipase C isoform delta K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D PHATRDRAFT_bd1000 phospholipase K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D PHATRDRAFT_bd1611 hypothetical protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D PHATRDRAFT_12431 hypothetical protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D PHATRDRAFT_49524 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PHATRDRAFT_25127 NDK3; nucleoside diphosphate kinase 3 K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D PHATRDRAFT_41676 NDK1; nucleoside diphosphate kinase 1 K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D PHATRDRAFT_42104 NDK2; nucleoside diphosphate kinase 2 K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
B Small GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PHATRDRAFT_21744 hypothetical protein K02183 CALM; calmodulin
D PHATRDRAFT_23794 CaM1; calmoduline K02183 CALM; calmodulin
D PHATRDRAFT_11956 UNC18; hypothetical protein K15292 STXBP1; syntaxin-binding protein 1
D PHATRDRAFT_573 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PHATRDRAFT_32173 hypothetical protein K13342 PEX5; peroxin-5
D PHATR_43871 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D PHATRDRAFT_bd465 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PHATRDRAFT_bd590 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PHATRDRAFT_28577 hypothetical protein K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
C Rho GTPases
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D PHATRDRAFT_42858 hypothetical protein K19985 EXOC6; exocyst complex component 6
C Exocyst complex assembly proteins
B Others
C Exomer complex
C Others
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
C Stx-Endo
C Stx-TGN / EE
D PHATR_13459 SytB; hypothetical protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D PHATRDRAFT_31489 hypothetical protein K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D PHATRDRAFT_40521 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
D PHATRDRAFT_43244 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D PHATRDRAFT_44364 GOS; hypothetical protein K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D PHATR_52139 Memb11; hypothetical protein K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
B SNAP-25[C] (Qc)
C STX6
D PHATRDRAFT_31559 hypothetical protein K08498 STX6; syntaxin 6
C STX8
C STX10
C Bet1
D PHATRDRAFT_37104 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D PHATRDRAFT_16798 hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
D PHATRDRAFT_17683 SybA; hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
D PHATRDRAFT_45601 SybD; hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D PHATRDRAFT_51073 SybF; hypothetical protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D PHATRDRAFT_54066 SybE; hypothetical protein K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D PHATRDRAFT_11956 UNC18; hypothetical protein K15292 STXBP1; syntaxin-binding protein 1
D PHATRDRAFT_43202 SLY1; hypothetical protein K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D PHATRDRAFT_42854 hypothetical protein K20029 ZDHHC3_7_25; palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]
D PHATRDRAFT_bd1578 hypothetical protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D PHATRDRAFT_12620 hypothetical protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D PHATR_13383 hypothetical protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D PHATRDRAFT_48103 SNAP; hypothetical protein K15296 NAPA; alpha-soluble NSF attachment protein
D PHATR_21083 hCdc48; hypothetical protein K13525 VCP; transitional endoplasmic reticulum ATPase
D PHATRDRAFT_34061 hypothetical protein K14012 NSFL1C; UBX domain-containing protein 1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D PHATRDRAFT_54801 CHC; hypothetical protein K04646 CLTC; clathrin heavy chain
C Dynamin
D PHATRDRAFT_54751 DYN1; hypothetical protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D PHATRDRAFT_54442 AP1alpha; hypothetical protein K11824 AP2A; AP-2 complex subunit alpha
D PHATRDRAFT_18142 AP2mu; hypothetical protein K11826 AP2M1; AP-2 complex subunit mu-1
D PHATRDRAFT_54935 AP2sigma; hypothetical protein K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D PHATRDRAFT_54019 HSP70A; protein heat shock protein Hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D PHATRDRAFT_49524 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D PHATRDRAFT_573 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
C Kinases
D PHATRDRAFT_14553 hypothetical protein K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C Ubiquitin E3 ligases
C Others
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D PHATRDRAFT_54751 DYN1; hypothetical protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D PHATRDRAFT_43251 Arf1; hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
C RhoA-dependent endocytosis
D PHATRDRAFT_54751 DYN1; hypothetical protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
B Macropinocytosis
C Ras GTPases
C Kinases
D PHATRDRAFT_30282 hypothetical protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
C Phospholipase C
D PHATRDRAFT_42683 PLC-delta; phospholipase C isoform delta K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D PHATRDRAFT_bd1000 phospholipase K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D PHATRDRAFT_bd1611 hypothetical protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D PHATRDRAFT_3137 hypothetical protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
C F-BAR proteins
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D PHATRDRAFT_51511 Rab5a; hypothetical protein K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D PHATRDRAFT_573 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PHATRDRAFT_30282 hypothetical protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PHATRDRAFT_49312 hypothetical protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D PHATR_36720 VPS45; hypothetical protein K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D PHATRDRAFT_43251 Arf1; hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf associated proteins
D PHATRDRAFT_21791 hypothetical protein K12486 SMAP; stromal membrane-associated protein
D PHATRDRAFT_45734 hypothetical protein K21841 TBC1D24; TBC1 domain family member 24
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D PHATRDRAFT_17109 hypothetical protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PHATRDRAFT_21501 hypothetical protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D PHATRDRAFT_51511 Rab5a; hypothetical protein K07889 RAB5C; Ras-related protein Rab-5C
D PHATRDRAFT_51199 Rab7; hypothetical protein K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D PHATR_43830 vacuolar protein sorting-associated protein 35 K18468 VPS35; vacuolar protein sorting-associated protein 35
D PHATRDRAFT_17936 hypothetical protein K18467 VPS29; vacuolar protein sorting-associated protein 29
D PHATRDRAFT_12113 hypothetical protein K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D PHATRDRAFT_45285 hypothetical protein K16536 HOOK3; protein HOOK3
C FERRY complex
C Rab associated proteins
D PHATRDRAFT_30282 hypothetical protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PHATRDRAFT_19004 hypothetical protein K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D PHATRDRAFT_5889 hypothetical protein K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D PHATR_43871 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D PHATRDRAFT_bd465 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PHATRDRAFT_bd590 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PHATRDRAFT_28577 hypothetical protein K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
B Arf GTPases and associated proteins
C Arf GTPases
D PHATRDRAFT_13157 hypothetical protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D PHATRDRAFT_24408 n-acetyl transferase K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D PHATRDRAFT_40101 hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
D PHATRDRAFT_28874 hypothetical protein K12183 TSG101; ESCRT-I complex subunit TSG101
D PHATRDRAFT_49632 hypothetical protein K12183 TSG101; ESCRT-I complex subunit TSG101
D PHATRDRAFT_19669 hypothetical protein K12184 VPS28; ESCRT-I complex subunit VPS28
D PHATRDRAFT_32539 hypothetical protein K12185 VPS37; ESCRT-I complex subunit VPS37
C ESCRT-II complex
D PHATRDRAFT_16493 hypothetical protein K12188 SNF8; ESCRT-II complex subunit VPS22
D PHATRDRAFT_38893 hypothetical protein K12189 VPS25; ESCRT-II complex subunit VPS25
D PHATRDRAFT_44534 hypothetical protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D PHATRDRAFT_11901 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D PHATRDRAFT_31375 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D PHATRDRAFT_5904 hypothetical protein K12191 CHMP2A; charged multivesicular body protein 2A
D PHATRDRAFT_38130 hypothetical protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D PHATR_18620 hypothetical protein K12198 CHMP5; charged multivesicular body protein 5
D PHATRDRAFT_49220 hypothetical protein K12195 CHMP6; charged multivesicular body protein 6
D PHATRDRAFT_30898 vacuolar protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D PHATRDRAFT_32097 hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D PHATRDRAFT_47496 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
B Tethering complex
C CORVET complex
D PHATRDRAFT_43103 hypothetical protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D PHATRDRAFT_43038 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D PHATRDRAFT_47275 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D PHATR_44037 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D PHATRDRAFT_42975 hypothetical protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D PHATRDRAFT_43038 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D PHATRDRAFT_47275 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D PHATR_44037 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D PHATRDRAFT_42975 hypothetical protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D PHATRDRAFT_46588 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D PHATRDRAFT_45316 hypothetical protein K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
C RAVE complex
D PHATRDRAFT_17276 Skp1_1; hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D PHATRDRAFT_54028 AP3delta; hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D PHATRDRAFT_54789 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D PHATRDRAFT_18241 AP3mu; hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D PHATRDRAFT_14536 AP3sigma; hypothetical protein K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Lysosomal membrane proteins
D PHATRDRAFT_43646 hypothetical protein K28023 MFSD1; MFS transporter, Pht family, lysosomal dipeptide transporter
D PHATRDRAFT_20026 hypothetical protein K05656 ABCB9; ATP-binding cassette, subfamily B (MDR/TAP), member 9
D PHATRDRAFT_43611 hypothetical protein K13783 SLC37A1_2; MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2
D PHATRDRAFT_52412 channel voltage activated chloride channel K05016 CLCN7; chloride channel 7
C Others
D PHATRDRAFT_12752 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PHATRDRAFT_2936 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PHATR_3692 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D PHATRDRAFT_31160 Rab11; hypothetical protein K07905 RAB11B; Ras-related protein Rab-11B
C Rab4 associated proteins
C Rab11 associated proteins
D PHATRDRAFT_24996 Sec13; hypothetical protein K14004 SEC13; protein transport protein SEC13
D PHATRDRAFT_42858 hypothetical protein K19985 EXOC6; exocyst complex component 6
C Other Rab GTPase associated proteins
D PHATRDRAFT_30394 hypothetical protein K12483 EHD1; EH domain-containing protein 1
D PHATRDRAFT_573 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PHATRDRAFT_54533 RAD51-g1; Rad51 DNA recombination/repair protein K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D PHATRDRAFT_45698 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D PHATRDRAFT_14850 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D PHATRDRAFT_32759 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D PHATRDRAFT_35252 f-actin capping protein K10364 CAPZA; F-actin-capping protein subunit alpha
D PHATRDRAFT_9601 protein of f-actin capping protein K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D PHATRDRAFT_17936 hypothetical protein K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D PHATRDRAFT_8918 hypothetical protein K23289 EIPR1; EARP and GARP complex-interacting protein 1
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PHATRDRAFT_42942 hypothetical protein K20164 DENND5; DENN domain-containing protein 5
D PHATRDRAFT_46620 DYNLRB; roadblock-related dynein light chain K10419 DYNLRB; dynein light chain roadblock-type
D PHATR_46726 hypothetical protein K04648 DCTN1; dynactin 1
D PHATRDRAFT_573 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
B Arf GTPases and associated proteins
C Arf GTPases
D PHATRDRAFT_43251 Arf1; hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D PHATRDRAFT_8659 ARL1; hypothetical protein K07942 ARL1; ADP-ribosylation factor-like protein 1
D PHATRDRAFT_bd231 hypothetical protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D PHATRDRAFT_50442 hypothetical protein K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D PHATRDRAFT_21791 hypothetical protein K12486 SMAP; stromal membrane-associated protein
D PHATRDRAFT_54591 Sec7D; hypothetical protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D PHATRDRAFT_50615 Sec7C; hypothetical protein K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D PHATRDRAFT_44776 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D PHATRDRAFT_43498 hypothetical protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D PHATRDRAFT_46005 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D PHATRDRAFT_42749 hypothetical protein K20292 COG5; conserved oligomeric Golgi complex subunit 5
D PHATRDRAFT_44715 hypothetical protein K20293 COG6; conserved oligomeric Golgi complex subunit 6
D PHATRDRAFT_43693 hypothetical protein K20294 COG7; conserved oligomeric Golgi complex subunit 7
D PHATRDRAFT_43008 hypothetical protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D PHATRDRAFT_45698 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D PHATRDRAFT_14850 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D PHATRDRAFT_32759 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D PHATRDRAFT_50446 hypothetical protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D PHATRDRAFT_33914 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PHATRDRAFT_42972 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PHATRDRAFT_9684 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PHATRDRAFT_42274 hypothetical protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PHATRDRAFT_10670 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PHATR_21198 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PHATRDRAFT_48567 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D PHATRDRAFT_49332 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D PHATRDRAFT_43136 hypothetical protein K20307 TRAPPC10; trafficking protein particle complex subunit 10
D PHATR_33217 hypothetical protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D PHATR_13511 hypothetical protein K12391 AP1G1; AP-1 complex subunit gamma-1
D PHATRDRAFT_bd1735 PtAP1/2beta; hypothetical protein K12392 AP1B1; AP-1 complex subunit beta-1
D PHATRDRAFT_54375 AP1mu; hypothetical protein K12393 AP1M; AP-1 complex subunit mu
D PHATRDRAFT_36149 AP1sigma; hypothetical protein K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D PHATRDRAFT_54028 AP3delta; hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D PHATRDRAFT_54789 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D PHATRDRAFT_18241 AP3mu; hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D PHATRDRAFT_14536 AP3sigma; hypothetical protein K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
D PHATRDRAFT_16891 hypothetical protein K12400 AP4E1; AP-4 complex subunit epsilon-1
D PHATRDRAFT_45284 AP4mu; hypothetical protein K12402 AP4M1; AP-4 complex subunit mu-1
D PHATRDRAFT_54718 AP4sigma; hypothetical protein K12403 AP4S1; AP-4 complex subunit sigma-1
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D PHATRDRAFT_12431 hypothetical protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D PHATRDRAFT_17109 hypothetical protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PHATRDRAFT_21501 hypothetical protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PHATRDRAFT_49524 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PHATR_33394 hypothetical protein K20318 SYS1; protein SYS1
D PHATRDRAFT_6052 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D PHATRDRAFT_46423 hypothetical protein K23544 SERINC1; serine incorporator 1
D PHATRDRAFT_45464 hypothetical protein K25661 SERINC3; serine incorporator 3
D PHATRDRAFT_bd748 hypothetical protein K27894 HID1; protein HID1
D PHATRDRAFT_6254 hypothetical protein K26752 TVP23; golgi apparatus membrane protein TVP23
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D PHATRDRAFT_54420 Sar1a; hypothetical protein K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D PHATRDRAFT_24996 Sec13; hypothetical protein K14004 SEC13; protein transport protein SEC13
D PHATRDRAFT_47010 hypothetical protein K14005 SEC31; protein transport protein SEC31
D PHATRDRAFT_42673 Sec23; hypothetical protein K14006 SEC23; protein transport protein SEC23
D PHATR_13396 hypothetical protein K14007 SEC24; protein transport protein SEC24
C TRAPP complex I
D PHATRDRAFT_33914 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PHATRDRAFT_42972 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PHATRDRAFT_9684 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PHATRDRAFT_42274 hypothetical protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PHATRDRAFT_10670 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PHATR_21198 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PHATRDRAFT_48567 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D PHATRDRAFT_49630 hypothetical protein K20347 TMED2; p24 family protein beta-1
D PHATRDRAFT_46215 hypothetical protein K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D PHATRDRAFT_2808 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D PHATRDRAFT_22713 Rab1a; hypothetical protein K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
D PHATRDRAFT_48415 hypothetical protein K20372 TBC1D20; TBC1 domain family member 20
D PHATRDRAFT_12157 hypothetical protein K20360 TBC1D22; TBC1 domain family member 2
D PHATRDRAFT_49392 hypothetical protein K20362 YIF1; protein transport protein YIF1
D PHATRDRAFT_10128 hypothetical protein K22939 IER3IP1; immediate early response 3-interacting protein 1
C ER-Golgi intermediate compartment (ERGIC) proteins
D PHATRDRAFT_bd36 hypothetical protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D PHATRDRAFT_9509 hypothetical protein K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D PHATRDRAFT_54246 BiP; ER luminal binding protein precursor K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D PHATRDRAFT_21929 hypothetical protein K05236 COPA; coatomer subunit alpha
D PHATRDRAFT_54511 COPbeta; hypothetical protein K17301 COPB1; coatomer subunit beta
D PHATRDRAFT_27518 COPbeta2; hypothetical protein K17302 COPB2; coatomer subunit beta'
D PHATR_10209 COPgamma; hypothetical protein K17267 COPG; coatomer subunit gamma
D PHATRDRAFT_30436 COPdelta; hypothetical protein K20471 COPD; coatomer subunit delta
D PHATRDRAFT_19093 COPIepsilon; hypothetical protein K17268 COPE; coatomer subunit epsilon
D PHATRDRAFT_7018 hypothetical protein K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D PHATRDRAFT_43019 Zw10 like protein K11578 ZW10; protein transport protein DSL1/ZW10
C Golgi to ER traffic proteins (GET)
D PHATRDRAFT_22896 hypothetical protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D PHATRDRAFT_32803 hypothetical protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
C Rab GTPases
C Rab associated proteins
D PHATRDRAFT_42126 hypothetical protein K10949 KDELR; ER lumen protein retaining receptor
D PHATRDRAFT_12157 hypothetical protein K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
C FXYD proteins
C YIPF proteins
D PHATRDRAFT_44631 hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D PHATRDRAFT_14502 hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D PHATR_5873 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D PHATRDRAFT_22797 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D PHATRDRAFT_12729 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D PHATRDRAFT_bd289 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
D PHATRDRAFT_35319 hypothetical protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
C SEC61 complex
D PHATRDRAFT_56443 Sec61alpha; transport protein Sec61 alpha subunit K10956 SEC61A; protein transport protein SEC61 subunit alpha
D PHATRDRAFT_17885 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D PHATRDRAFT_49185 hypothetical protein K21891 TMCO1; calcium load-activated calcium channel
C Post-GPI attachment to proteins factors (PGAP)
C Others
D PHATRDRAFT_43202 SLY1; hypothetical protein K19998 SCFD1; sec1 family domain-containing protein 1
D PHATRDRAFT_47706 hypothetical protein K21848 ARV1; lipid intermediate transporter
D PHATRDRAFT_32237 hypothetical protein K22556 MANF; mesencephalic astrocyte-derived neurotrophic factor
D PHATRDRAFT_54726 anti-viral guanylate-binding protein K17339 ATL; atlastin [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
C Atg1 complex
D PHATRDRAFT_5526 hCDK6; hypothetical protein K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
C PI3K complex
D PHATRDRAFT_30282 hypothetical protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PHATRDRAFT_49312 hypothetical protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D PHATRDRAFT_31423 hypothetical protein K08334 BECN; beclin
D PHATRDRAFT_43402 hypothetical protein K08334 BECN; beclin
C ATG9 transmembrane protein
D PHATRDRAFT_36572 hypothetical protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
C Atg12 conjugation proteins
D PHATRDRAFT_9342 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D PHATR_43913 hypothetical protein K08339 ATG5; autophagy-related protein 5
D PHATRDRAFT_43401 hypothetical protein K17890 ATG16L1; autophagy-related protein 16-1
C Atg8 conjugation proteins
D PHATRDRAFT_50303 hypothetical protein K08341 GABARAP; GABA(A) receptor-associated protein
D PHATRDRAFT_9342 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D PHATRDRAFT_41667 hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D PHATR_52108 glycosyl hydrolase/mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D PHATRDRAFT_20708 hypothetical protein K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
D PHATRDRAFT_27719 hypothetical protein K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D PHATR_44229 hypothetical protein K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
B Mitophagy
C Cargo receptors
C Scaffold proteins
D PHATR_44229 hypothetical protein K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D PHATRDRAFT_49498 hypothetical protein K19513 CLEC16A; protein CLEC16A
C Other mitophagy associated proteins
B Pexophagy
C Selective cargos
D PHATRDRAFT_50623 hypothetical protein K13336 PEX3; peroxin-3
C Cargo receptors
C Other pexophagy associated proteins
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D PHATR_21083 hCdc48; hypothetical protein K13525 VCP; transitional endoplasmic reticulum ATPase
D PHATRDRAFT_35869 hypothetical protein K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D PHATRDRAFT_45906 hypothetical protein K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B ER-phagy
C ER-phagy recepters
D PHATRDRAFT_47099 hypothetical protein K12275 SEC62; translocation protein SEC62
D PHATRDRAFT_54726 anti-viral guanylate-binding protein K17339 ATL; atlastin [EC:3.6.5.-]
C Other ER-phagy associated proteins
D PHATR_44171 hypothetical protein K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C ER stress-related proteins
D PHATRDRAFT_54246 BiP; ER luminal binding protein precursor K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D PHATRDRAFT_16786 hypothetical protein K09487 HSP90B; heat shock protein 90kDa beta
D PHATRDRAFT_34538 hypothetical protein K03237 EIF2S1; translation initiation factor 2 subunit 1
B Chaperone mediated autophagy (CMA)
C Selective cargos
D PHATRDRAFT_42447 Fba4; cytosolic aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D PHATRDRAFT_51289 FbaC5; fructose-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D PHATRDRAFT_22122 GapC1; glyceraldehyde-3-phosphate dehydrogenase precursor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PHATRDRAFT_25308 TPI/GapC3; triosephosphate isomerase/glyceraldehyde-3-phosphate dehydrogenase precursor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PHATRDRAFT_32747 GapC4; hypothetical protein K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PHATRDRAFT_51128 GapC2a; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PHATRDRAFT_51129 GapC2b; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PHATRDRAFT_26201 PGAM_5; hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PHATRDRAFT_33839 PGAM_6; hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PHATRDRAFT_42857 PGAM_1; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PHATRDRAFT_43253 PGAM_2; hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PHATRDRAFT_51298 PGAM_4; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PHATR_43812 PGAM_3; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PHATRDRAFT_49002 PK5; kinase pyruvate kinase 5 K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PHATRDRAFT_49098 PK2; kinase pyruvate kinase 2 K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PHATRDRAFT_56172 PK6; kinase pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PHATRDRAFT_56445 PK3; kinase pyruvate kinase 3 K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PHATRDRAFT_44323 hypothetical protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D PHATRDRAFT_54019 HSP70A; protein heat shock protein Hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PHATRDRAFT_55230 hypothetical protein K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
D PHATRDRAFT_9462 hypothetical protein K09560 ST13; suppressor of tumorigenicity protein 13
C Other CMA associated proteins
D PHATRDRAFT_28737 hypothetical protein K03231 EEF1A; elongation factor 1-alpha
D PHATR_18475 EF-1; translation elongation factor, EF-1, alpha subunit K03231 EEF1A; elongation factor 1-alpha
D PHATRDRAFT_11204 hypothetical protein K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
D PHATR_18551 hypothetical protein K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
C mTORC1 complex
D PHATRDRAFT_21660 hypothetical protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D PHATRDRAFT_36142 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
D PHATR_18549 hypothetical protein K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D PHATRDRAFT_21660 hypothetical protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D PHATRDRAFT_36142 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
C SEACIT/GATOR1 complex
D PHATRDRAFT_48390 hypothetical protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D PHATRDRAFT_43499 hypothetical protein K20405 NPRL2; nitrogen permease regulator 2
C SEACAT/GATOR2 complex
D PHATR_46891 hypothetical protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D PHATR_44239 hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D PHATRDRAFT_4700 hypothetical protein K14299 SEH1; nucleoporin SEH1
D PHATRDRAFT_24996 Sec13; hypothetical protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D PHATRDRAFT_22713 Rab1a; hypothetical protein K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
C Others
D PHATRDRAFT_8773 MARK3; hypothetical protein K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D PHATRDRAFT_22247 hypothetical protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D PHATRDRAFT_51017 hypothetical protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D PHATRDRAFT_bd800 hypothetical protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D PHATRDRAFT_43438 hypothetical protein K17606 IGBP1; immunoglobulin-binding protein 1
D PHATRDRAFT_40517 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D PHATRDRAFT_45824 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D PHATRDRAFT_49568 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
B Actin-binding proteins
C Myosins
D PHATRDRAFT_432 myoA4; hypothetical protein K10357 MYO5; myosin V
D PHATRDRAFT_54688 myoA3; hypothetical protein K10357 MYO5; myosin V
C Arp2/3 complex
C Nucleation-promoting factors (NPFs)
D PHATRDRAFT_bd741 hypothetical protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
C Others
D PHATRDRAFT_15613 hypothetical protein K05765 CFL; cofilin
B Mucins
C Membrane bound mucins
C Secretory mucins
B MARVEL domain-containing proteins
B Specific organelles associated proteins
C Melanosome
C Auto phagosome
D PHATRDRAFT_43401 hypothetical protein K17890 ATG16L1; autophagy-related protein 16-1
C Lipid droplets
D PHATRDRAFT_51810 Rab18; hypothetical protein K07910 RAB18; Ras-related protein Rab-18
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
C Rho guanine nucleotide exchange factors (GEFs)
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 3, 2025