+C Two-component system KO
#
Two-Component System - Pseudomonas vanderleydeniana
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C HU752_000475 phoR; phosphate regulon sensor histidine kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C HU752_000470 phoB; phosphate regulon transcriptional regulator PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
C HU752_025850 histidine kinase K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C HU752_025855 response regulator K07660 phoP; two-component system, OmpR family, response regulator PhoP
B EnvZ-OmpR (osmotic stress response)
C HU752_031105 HAMP domain-containing protein K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C HU752_031110 ompR; two-component system response regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C HU752_025865 HAMP domain-containing protein K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C HU752_025870 response regulator K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C HU752_008895 response regulator transcription factor K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C HU752_030015 creC; two-component system sensor histidine kinase CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C HU752_030020 creB; two-component system response regulator CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
C HU752_019765 HAMP domain-containing protein K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
C HU752_019760 response regulator K07664 baeR; two-component system, OmpR family, response regulator BaeR
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C HU752_005935 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C HU752_010295 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C HU752_021930 heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C HU752_005940 heavy metal response regulator transcription factor K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C HU752_010300 heavy metal response regulator transcription factor K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C HU752_021925 heavy metal response regulator transcription factor K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
C HU752_011970 sensor histidine kinase N-terminal domain-containing protein K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C HU752_019355 sensor histidine kinase N-terminal domain-containing protein K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C HU752_023620 sensor histidine kinase N-terminal domain-containing protein K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C HU752_011975 response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
C HU752_019360 response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
C HU752_023625 response regulator transcription factor K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C HU752_025120 sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C HU752_025115 response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C HU752_007180 sensor histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C HU752_007175 response regulator K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
C HU752_021365 HAMP domain-containing protein K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
C HU752_021370 winged helix-turn-helix domain-containing protein K18073 parR; two-component system, OmpR family, response regulator ParR
B AdeS-AdeR
C HU752_022120 HAMP domain-containing protein K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
C HU752_022125 response regulator K18144 adeR; two-component system, OmpR family, response regulator AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
C HU752_025765 sensor histidine kinase K19609 pfeS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]
C HU752_025770 response regulator transcription factor K19610 pfeR; two-component system, OmpR family, response regulator PfeR
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C HU752_018225 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C HU752_018785 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C HU752_008885 HAMP domain-containing histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C HU752_015880 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C HU752_018230 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C HU752_018620 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C HU752_018790 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C HU752_025145 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C HU752_026455 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C HU752_026720 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C HU752_022925 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
#
ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
C HU752_000015 response regulator transcription factor K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C HU752_006595 response regulator transcription factor K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
B BarA-UvrY (central carbon metabolism)
C HU752_025775 response regulator K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C HU752_022280 uvrY; UvrY/SirA/GacA family response regulator transcription factor K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C HU752_006585 transporter substrate-binding domain-containing protein K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C HU752_023980 transporter substrate-binding domain-containing protein K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C HU752_023460 response regulator transcription factor K07690 evgA; two-component system, NarL family, response regulator EvgA
C HU752_023975 response regulator transcription factor K07690 evgA; two-component system, NarL family, response regulator EvgA
C HU752_026850 response regulator transcription factor K07690 evgA; two-component system, NarL family, response regulator EvgA
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
C HU752_004170 PAS domain-containing protein K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]
C HU752_004155 response regulator transcription factor K27077 pprB; two-component system, NarL family, response regulator PprB
B Unclassified
C HU752_016855 cache domain-containing protein K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
#
ASpo family
B KinABCDE-Spo0FA (sporulation control)
#
ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
#
ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C HU752_031480 sensor histidine kinase K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
C HU752_031475 LytTR family DNA-binding domain-containing protein K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
#
ANtrC family
B GlnL-GlnG (nitrogen regulation)
C HU752_002715 glnL; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C HU752_002710 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C HU752_028590 sigma-54 dependent transcriptional regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
C HU752_005260 PAS domain-containing sensor histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C HU752_005255 sigma-54 dependent transcriptional regulator K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C HU752_002435 GHKL domain-containing protein K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C HU752_007915 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C HU752_002430 sigma-54 dependent transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C HU752_007910 sigma-54 dependent transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
C HU752_001495 PAS domain-containing protein K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
C HU752_001500 algB; sigma-54-dependent response regulator transcription factor AlgB K11384 algB; two-component system, NtrC family, response regulator AlgB
B HupT-HupR (hydrogenase synthesis regulation)
C HU752_014655 hydrogenase maturation protein K19640 hypX; putative two-component system protein, hydrogenase maturation factor HypX/HoxX
B Unclassified
C HU752_027085 response regulator K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
#
ACheA family
B CheA-CheYBV (chemotaxis)
C HU752_002365 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C HU752_009255 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C HU752_015050 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C HU752_015085 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C HU752_002375 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C HU752_009245 chemotaxis response regulator CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C HU752_015075 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C HU752_002340 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C HU752_009260 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C HU752_015020 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C HU752_015110 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C HU752_017095 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C HU752_006005 chemotaxis protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C HU752_010155 chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C HU752_025905 chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
C HU752_030635 Hpt domain-containing protein K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C HU752_030655 pilG; twitching motility response regulator PilG K02657 pilG; twitching motility two-component system response regulator PilG
C HU752_030650 pilH; twitching motility response regulator PilH K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
C HU752_006715 hybrid sensor histidine kinase/response regulator K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
C HU752_006725 PleD family two-component system response regulator K11444 wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65]
C HU752_006720 chemotaxis response regulator protein-glutamate methylesterase K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
B Cph1-Rcp1 (light response)
#
ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
C HU752_017085 response regulator K13589 cpdR; two-component system, cell cycle response regulator CpdR
B Hk1-Rrp1 (glycerol uptake and utilization)
#
ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
#
ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
#
AOther families
B FlrB-FlrC (polar flagellar synthesis)
C HU752_009125 PAS domain-containing protein K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C HU752_009130 fleR; sigma-54-dependent response regulator transcription factor FleR K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
C HU752_026975 sensor histidine kinase K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
C HU752_026980 sigma-54 dependent transcriptional regulator K17061 aauR; two-component system, response regulator AauR
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C HU752_005560 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C HU752_005565 response regulator transcription factor K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C HU752_024000 response regulator K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
C HU752_025220 response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
C HU752_009175 Hpt domain-containing protein K20976 hptB; histidine phosphotransfer protein HptB
C HU752_009170 SpoIIE family protein phosphatase K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator
B PdtaS-PdtaR
B NasS-NasT
C HU752_024855 ABC transporter substrate-binding protein K22067 nasS; two-component system, oxyanion-binding sensor
C HU752_024860 ANTAR domain-containing response regulator K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
C HU752_004695 response regulator K20971 ladS; two-component system, sensor histidine kinase LadS
C HU752_004015 response regulator K20972 retS; two-component system, sensor histidine kinase RetS
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023