+C Two-component system KO
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Two-Component System - Pseudomonas yamanorum
%
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C AK972_6038 Phosphate regulon sensor protein PhoR (SphS) K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C AK972_6039 Phosphate regulon transcriptional regulatory protein PhoB (SphR) K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
C AK972_1329 Sensor protein PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C AK972_1328 Transcriptional regulatory protein PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
B EnvZ-OmpR (osmotic stress response)
C AK972_5688 Osmolarity sensory histidine kinase EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C AK972_5689 Two-component system response regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C AK972_1325 Sensor protein K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C AK972_1324 Transcriptional regulatory protein RstA K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C AK972_1152 DNA-binding response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C AK972_0293 Two-component response regulator CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C AK972_0292 Two-component response regulator CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C AK972_3837 Heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C AK972_4220 Osmosensitive K+ channel histidine kinase KdpD K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C AK972_5087 Heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C AK972_0813 Heavy metal sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C AK972_3836 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C AK972_4219 Copper-sensing two-component system response regulator CusR K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C AK972_5086 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C AK972_5091 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C AK972_5746 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
C AK972_0812 DNA-binding heavy metal response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
C AK972_4876 Sensory histidine kinase QseC K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C AK972_1704 Sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C AK972_4877 Two-component system response regulator QseB K07666 qseB; two-component system, OmpR family, response regulator QseB
C AK972_1703 Two-component system response regulator QseB K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C AK972_4145 Osmosensitive K+ channel histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C AK972_1654 Osmosensitive K+ channel histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C AK972_4144 sensor histidine kinase K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
C AK972_1653 sensor histidine kinase K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C AK972_4528 Tricarboxylate transport sensor protein TctE K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C AK972_4529 Tricarboxylate transport transcriptional regulator TctD K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
C AK972_2784 Sensory histidine kinase in two-component regulatory system with RstA K18072 parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
C AK972_2783 Transcriptional regulatory protein RstA K18073 parR; two-component system, OmpR family, response regulator ParR
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
C AK972_1348 Two-component sensor histidine kinase PfeS, enterobactin K19609 pfeS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]
C AK972_1347 Two-component response regulator PfeR, enterobactin K19610 pfeR; two-component system, OmpR family, response regulator PfeR
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C AK972_2507 Sensory histidine kinase QseC K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C AK972_3849 hypothetical protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C AK972_4666 Phosphate regulon transcriptional regulatory protein PhoB (SphR) K02483 K02483; two-component system, OmpR family, response regulator
C AK972_4897 DNA-binding response regulator GltR, controls specific porins for the entry of glucose K02483 K02483; two-component system, OmpR family, response regulator
C AK972_2506 Transcriptional regulatory protein RstA K02483 K02483; two-component system, OmpR family, response regulator
C AK972_3848 Two-component system response regulator QseB K02483 K02483; two-component system, OmpR family, response regulator
C AK972_1612 DNA-binding response regulator GltR, controls specific porins for the entry of glucose K02483 K02483; two-component system, OmpR family, response regulator
C AK972_2039 Transcriptional regulatory protein ompR K02483 K02483; two-component system, OmpR family, response regulator
C AK972_3567 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C AK972_3671 Two-component system response regulator QseB K02483 K02483; two-component system, OmpR family, response regulator
C AK972_1062 DNA-binding response regulator GltR, controls specific porins for the entry of glucose K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
C AK972_3960 sensor histidine kinase/response regulator K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C AK972_3962 Signal transduction histidine kinase K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C AK972_4791 DNA-binding response regulator, LuxR family K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C AK972_3963 two component transcriptional regulator, LuxR family K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C AK972_0869 two component transcriptional regulator, LuxR family K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
C AK972_2112 Two-component response regulator K07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
B BarA-UvrY (central carbon metabolism)
C AK972_1346 BarA sensory histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C AK972_2107 BarA-associated response regulator UvrY K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C AK972_2885 Hybrid sensory histidine kinase in two-component regulatory system with EvgA K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C AK972_2915 Hybrid sensory histidine kinase in two-component regulatory system with EvgA K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C AK972_4793 Signal transduction histidine kinase K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C AK972_4084 Hybrid sensory histidine kinase in two-component regulatory system with EvgA K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C AK972_3493 Hybrid sensory histidine kinase in two-component regulatory system with EvgA K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C AK972_2111 sensory box histidine kinase/response regulator K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
C AK972_2886 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
C AK972_2916 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
C AK972_4083 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
C AK972_0962 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
C AK972_3494 DNA-binding response regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
C AK972_5273 Sensory box histidine kinase K27076 pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]
C AK972_5270 DNA-binding response regulator, LuxR family K27077 pprB; two-component system, NarL family, response regulator PprB
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C AK972_6142 Autolysis response regulater LytR K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C AK972_5575 Nitrogen regulation protein NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C AK972_5576 Nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C AK972_5132 Two-component sensor CbrB: intrcellular carbon:nitrogen balance K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C AK972_5662 Signal transduction histidine kinase regulating C4-dicarboxylate transport system K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C AK972_1071 C4-dicarboxylate transport sensor protein K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C AK972_5663 C4-dicarboxylate transport transcriptional regulatory protein K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C AK972_1070 Nitrogen regulation protein NR(I) K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
C AK972_5844 Sensory box histidine kinase K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
C AK972_5843 Alginate biosynthesis transcriptional regulatory protein algB K11384 algB; two-component system, NtrC family, response regulator AlgB
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C AK972_0920 Signal transduction histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C AK972_0921 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C AK972_1503 Signal transduction histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C AK972_1501 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C AK972_2807 Protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C AK972_1504 Chemotaxis response regulator protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C AK972_1315 Chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C AK972_0804 Chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C AK972_1684 Chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
C AK972_0179 Signal transduction histidine kinase CheA K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C AK972_0175 twitching motility protein PilG K02657 pilG; twitching motility two-component system response regulator PilG
C AK972_0176 twitching motility protein PilH K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
C AK972_4764 Sensor histidine kinase/response regulator K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
C AK972_4762 diguanylate cyclase (GGDEF domain) with PAS/PAC sensor K11444 wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65]
C AK972_4763 Chemotaxis response regulator protein-glutamate methylesterase CheB K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
B Cph1-Rcp1 (light response)
C AK972_4895 Phytochrome, two-component sensor histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
C AK972_1779 Phytochrome, two-component sensor histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
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ACell cycle family
B PleC-PleD (cell fate control)
C AK972_2931 Signal transduction response regulator K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
C AK972_2809 Response regulator K13589 cpdR; two-component system, cell cycle response regulator CpdR
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C AK972_1476 Flagellar sensor histidine kinase FleS K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C AK972_1477 Flagellar regulatory protein FleQ K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
C AK972_0939 Signal transduction histidine kinase regulating C4-dicarboxylate transport system K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
C AK972_0938 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake K17061 aauR; two-component system, response regulator AauR
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C AK972_0680 Sensor histidine kinase PrrB (RegB) K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C AK972_0681 Dna binding response regulator PrrA (RegA) K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C AK972_4087 sensor histidine kinase/response regulator K20973 sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]
C AK972_1598 Sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
C AK972_1486 Hpt domain protein K20976 hptB; histidine phosphotransfer protein HptB
C AK972_1485 Serine phosphatase RsbU, regulator of sigma subunit K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator
B PdtaS-PdtaR
B NasS-NasT
C AK972_4311 Nitrate ABC transporter, nitrate-binding protein K22067 nasS; two-component system, oxyanion-binding sensor
C AK972_4312 Response regulator NasT K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
C AK972_0530 Sensor histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS
C AK972_5300 Sensor histidine kinase/response regulator K20972 retS; two-component system, sensor histidine kinase RetS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023