+E Ubiquitin system KO
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Ubiquitin System - Herpailurus yagouaroundi (jaguarundi)
%
!
AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 121011025 UBA52; ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 121016283 RPS27A; ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 121024997 LOW QUALITY PROTEIN: ubiquitin-40S ribosomal protein S27a-like K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 121026147 ubiquitin-40S ribosomal protein S27a-like K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 121018398 UBD; LOW QUALITY PROTEIN: ubiquitin D K12157 UBD; ubiquitin D
C 121031567 NEDD8; NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 121012087 LOW QUALITY PROTEIN: ubiquitin-like protein FUBI K02983 RP-S30e; small subunit ribosomal protein S30e
C 121023716 FAU; ubiquitin-like protein fubi and ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
C 121018837 ISG15; ubiquitin-like protein ISG15 K12159 ISG15; ubiquitin cross-reactive protein
C 121012851 small ubiquitin-related modifier 1-like K12160 SUMO; small ubiquitin-related modifier
C 121016828 small ubiquitin-related modifier 1-like K12160 SUMO; small ubiquitin-related modifier
C 121017905 SUMO2; small ubiquitin-related modifier 2 isoform X1 K12160 SUMO; small ubiquitin-related modifier
C 121025714 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 121028736 small ubiquitin-related modifier 1-like K12160 SUMO; small ubiquitin-related modifier
C 121028951 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 121030923 SUMO1; small ubiquitin-related modifier 1 isoform X1 K12160 SUMO; small ubiquitin-related modifier
C 121035860 SUMO3; small ubiquitin-related modifier 3 isoform X1 K12160 SUMO; small ubiquitin-related modifier
C 121036518 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 121037173 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 121009809 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1 K08341 GABARAP; GABA(A) receptor-associated protein
C 121016026 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 121038952 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
C 121010556 ATG12; ubiquitin-like protein ATG12 isoform X1 K08336 ATG12; ubiquitin-like protein ATG12
C 121012874 UFM1; ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
C 121012798 UBL3; ubiquitin-like protein 3 K28515 UBL3; membrane-anchored ubiquitin-fold protein
C 121036942 ZFAND4; AN1-type zinc finger protein 4 isoform X1 K12163 ZFAND4; AN1-type zinc finger protein 4
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 121026175 UBA1; ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 121018677 SAE1; SUMO-activating enzyme subunit 1 isoform X1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 121011604 UBA2; SUMO-activating enzyme subunit 2 isoform X1 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 121016734 UBA3; NEDD8-activating enzyme E1 catalytic subunit isoform X1 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 121045417 NAE1; NEDD8-activating enzyme E1 regulatory subunit isoform X1 K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 121019872 MOCS3; adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 121033677 UBA5; ubiquitin-like modifier-activating enzyme 5 isoform X1 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 121011211 UBA7; ubiquitin-like modifier-activating enzyme 7 isoform X1 K10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
C 121034906 UBA6; ubiquitin-like modifier-activating enzyme 6 isoform X1 K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C 121041251 ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X1 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 121025481 UBE2A; ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 121010708 UBE2B; ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C 121012114 UBE2C; ubiquitin-conjugating enzyme E2 C isoform X1 K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 121044707 ubiquitin-conjugating enzyme E2 C-like K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 121010793 UBE2D2; ubiquitin-conjugating enzyme E2 D2 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 121031821 UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 121036653 UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 121030772 UBE2E3; ubiquitin-conjugating enzyme E2 E3 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 121033595 ubiquitin-conjugating enzyme E2 E1 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 121033598 UBE2E2; ubiquitin-conjugating enzyme E2 E2 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 121016098 UBE2G1; ubiquitin-conjugating enzyme E2 G1 isoform X1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 121035859 UBE2G2; ubiquitin-conjugating enzyme E2 G2 isoform X1 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 121028347 UBE2H; ubiquitin-conjugating enzyme E2 H isoform X1 K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 121029775 UBE2J1; ubiquitin-conjugating enzyme E2 J1 isoform X1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 121018934 UBE2J2; ubiquitin-conjugating enzyme E2 J2 isoform X1 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 121036764 UBE2K; ubiquitin-conjugating enzyme E2 K K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 121023028 UBE2L3; ubiquitin-conjugating enzyme E2 L3 isoform X1 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 121043405 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X1 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 121040621 UBE2N; ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 121044414 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 121018130 UBE2O; (E3-independent) E2 ubiquitin-conjugating enzyme K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 121015464 UBE2Q1; ubiquitin-conjugating enzyme E2 Q1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 121042050 UBE2Q2; ubiquitin-conjugating enzyme E2 Q2 isoform X1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 121021889 CDC34; ubiquitin-conjugating enzyme E2 R1 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 121034581 UBE2R2; ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 121023438 UBE2S; ubiquitin-conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 121021625 UBE2T; ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 121027251 UBE2U; ubiquitin-conjugating enzyme E2 U isoform X1 K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
C 121038114 UBE2W; ubiquitin-conjugating enzyme E2 W K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 121044828 UBE2Z; ubiquitin-conjugating enzyme E2 Z K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
C 121044324 BIRC6; baculoviral IAP repeat-containing protein 6 isoform X1 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 121019734 UBE2I; SUMO-conjugating enzyme UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 121014365 UBE2F; NEDD8-conjugating enzyme UBE2F isoform X1 K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 121023417 UBE2M; NEDD8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 121043405 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X1 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 121036235 ATG3; ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 121013659 ATG10; ubiquitin-like-conjugating enzyme ATG10 isoform X1 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 121015484 UFC1; ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 121042535 UBE3A; ubiquitin-protein ligase E3A isoform X1 K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 121010182 UBE3B; ubiquitin-protein ligase E3B isoform X1 K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 121022918 UBE3C; ubiquitin-protein ligase E3C isoform X1 K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 121029728 UBE3D; E3 ubiquitin-protein ligase E3D isoform X1 K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 121015285 SMURF2; E3 ubiquitin-protein ligase SMURF2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 121017436 SMURF1; E3 ubiquitin-protein ligase SMURF1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 121012287 ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1 K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
C 121038026 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 121009728 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1 K05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
C 121014462 TRIP12; E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 121041744 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 121032879 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
C 121024799 HUWE1; E3 ubiquitin-protein ligase HUWE1 isoform X1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 121032047 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 121042799 UBR5; E3 ubiquitin-protein ligase UBR5 isoform X1 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 121031609 G2E3; G2/M phase-specific E3 ubiquitin-protein ligase isoform X1 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 121041814 HERC1; probable E3 ubiquitin-protein ligase HERC1 isoform X1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 121042571 HERC2; E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 121032708 HERC3; probable E3 ubiquitin-protein ligase HERC3 K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
C 121036696 HERC4; probable E3 ubiquitin-protein ligase HERC4 isoform X1 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 121029832 HACE1; E3 ubiquitin-protein ligase HACE1 isoform X1 K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]
C 121028940 HECW1; E3 ubiquitin-protein ligase HECW1 isoform X1 K12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]
C 121030857 HECW2; E3 ubiquitin-protein ligase HECW2 isoform X1 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 121031614 HECTD1; E3 ubiquitin-protein ligase HECTD1 isoform X1 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 121036988 HECTD2; probable E3 ubiquitin-protein ligase HECTD2 isoform X1 K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C 121027025 HECTD3; E3 ubiquitin-protein ligase HECTD3 isoform X1 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 121010322 HECTD4; probable E3 ubiquitin-protein ligase HECTD4 isoform X1 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 121016462 NDFIP1; NEDD4 family-interacting protein 1 K25839 NDFIP; NEDD4 family-interacting protein
D 121037817 NDFIP2; NEDD4 family-interacting protein 2 K25839 NDFIP; NEDD4 family-interacting protein
D 121026830 NEDD4-binding protein 3 K26473 N4BP3; NEDD4-binding protein 3
D 121026833 NEDD4-binding protein 3 K26473 N4BP3; NEDD4-binding protein 3
D 121019538 CUNH16orf72; UPF0472 protein C16orf72 homolog K27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1
D 121025819 UPF0472 protein C16orf72 K27700 HAPSTR2; HUWE1-associated protein modifying stress responses 2
B U-box type E3
C 121035467 UBE4A; ubiquitin conjugation factor E4 A isoform X1 K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 121020679 UBE4B; ubiquitin conjugation factor E4 B isoform X1 K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 121019768 STUB1; E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 121023029 PPIL2; RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 121043346 PRPF19; pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 121019367 RBBP6; E3 ubiquitin-protein ligase RBBP6 isoform X1 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 121012427 UBOX5; RING finger protein 37 isoform X1 K10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D 121022211 RNF40; E3 ubiquitin-protein ligase BRE1B K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
D 121034766 RNF20; E3 ubiquitin-protein ligase BRE1A K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 121035512 CBL; E3 ubiquitin-protein ligase CBL isoform X1 K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 121036187 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1 K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
D 121018579 CBLC; E3 ubiquitin-protein ligase CBL-C isoform X1 K22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 121025635 E3 ubiquitin-protein ligase SIAH1-like K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 121045253 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 121033840 SIAH2; E3 ubiquitin-protein ligase SIAH2 K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
C Ligand of Numb proteins
D 121012772 LNX2; ligand of Numb protein X 2 isoform X1 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 121035586 LNX1; E3 ubiquitin-protein ligase LNX isoform X1 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 121038716 PDZ domain-containing RING finger protein 4 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
D 121041353 PDZRN3; E3 ubiquitin-protein ligase PDZRN3 isoform X1 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 121027613 MARCHF1; E3 ubiquitin-protein ligase MARCHF1 isoform X1 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 121036943 MARCHF8; E3 ubiquitin-protein ligase MARCHF8 isoform X1 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 121010636 MARCHF3; E3 ubiquitin-protein ligase MARCHF3 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 121013882 MARCHF2; E3 ubiquitin-protein ligase MARCHF2 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 121031035 MARCHF4; E3 ubiquitin-protein ligase MARCHF4 isoform X1 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 121040859 MARCHF9; E3 ubiquitin-protein ligase MARCHF9 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 121041579 MARCHF11; E3 ubiquitin-protein ligase MARCHF11 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 121036994 MARCHF5; E3 ubiquitin-protein ligase MARCHF5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 121042689 MARCHF6; E3 ubiquitin-protein ligase MARCHF6 isoform X1 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
D 121031117 MARCHF7; E3 ubiquitin-protein ligase MARCHF7 isoform X1 K10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]
D 121015243 MARCHF10; probable E3 ubiquitin-protein ligase MARCHF10 isoform X1 K10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 121040772 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
D 121021664 MDM4; protein Mdm4 K10127 MDM4; protein Mdm4
C NFX1 proteins
D 121034572 NFX1; transcriptional repressor NF-X1 isoform X1 K12236 NFX1; transcriptional repressor NF-X1
D 121036165 NFXL1; NF-X1-type zinc finger protein NFXL1 isoform X1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 121019108 PELI1; E3 ubiquitin-protein ligase pellino homolog 1 K11964 PELI; pellino [EC:2.3.2.27]
D 121023918 PELI3; E3 ubiquitin-protein ligase pellino homolog 3 isoform X1 K11964 PELI; pellino [EC:2.3.2.27]
D 121031808 PELI2; E3 ubiquitin-protein ligase pellino homolog 2 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 121019428 PEX10; peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 121017110 PEX12; peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 121038097 PEX2; peroxisome biogenesis factor 2 isoform X1 K06664 PEX2; peroxin-2
C RBR proteins
D 121013069 PRKN; E3 ubiquitin-protein ligase parkin isoform X1 K04556 PARK2; parkin [EC:2.3.2.31]
D 121028751 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 isoform X1 K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 121041956 ARIH1; E3 ubiquitin-protein ligase ARIH1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 121011175 ARIH2; E3 ubiquitin-protein ligase ARIH2 isoform X1 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 121012362 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 121016480 RNF14; E3 ubiquitin-protein ligase RNF14 isoform X1 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 121042776 RNF19A; E3 ubiquitin-protein ligase RNF19A K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 121017516 RNF19B; E3 ubiquitin-protein ligase RNF19B K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]
D 121031551 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 121010461 RNF34; E3 ubiquitin-protein ligase RNF34 isoform X1 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 121017122 RFFL; E3 ubiquitin-protein ligase rififylin isoform X1 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 121020527 RNF144B; E3 ubiquitin-protein ligase RNF144B K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 121044055 RNF144A; E3 ubiquitin-protein ligase RNF144A isoform X1 K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 121026044 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF168-like K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 121036388 RNF168; E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 121039171 RNF169; E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
D 121034856 RNF183; E3 ubiquitin-protein ligase RNF183 K22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]
D 121017539 RNF216; E3 ubiquitin-protein ligase RNF216 isoform X1 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 121030095 RNF217; probable E3 ubiquitin-protein ligase RNF217 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
C TRAF proteins
D 121020261 TRAF2; TNF receptor-associated factor 2 isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 121011741 TRAF5; TNF receptor-associated factor 5 isoform X1 K09849 TRAF5; TNF receptor-associated factor 5
D 121043535 TRAF6; TNF receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 121019678 TRAF7; E3 ubiquitin-protein ligase TRAF7 isoform X1 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 121025756 MID2; probable E3 ubiquitin-protein ligase MID2 isoform X1 K10647 TRIM1; midline 2 [EC:2.3.2.27]
D 121021122 TRIM3; tripartite motif-containing protein 3 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 121028393 TRIM2; tripartite motif-containing protein 2 isoform X1 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 121017811 TRIM4; E3 ubiquitin-protein ligase TRIM4 K11998 TRIM4; tripartite motif-containing protein 4 [EC:2.3.2.27]
D 121021158 uncharacterized protein LOC121021158 isoform X1 K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 121021159 TRIM6; tripartite motif-containing protein 6 isoform X1 K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 121021160 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM22-like K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 121016642 TRIM7; E3 ubiquitin-protein ligase TRIM7 isoform X1 K12000 TRIM7; tripartite motif-containing protein 7
D 121037165 TRIM8; E3 ubiquitin-protein ligase TRIM8 K12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]
D 121023136 TRIM67; tripartite motif-containing protein 67 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 121031756 TRIM9; E3 ubiquitin-protein ligase TRIM9 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 121018376 tripartite motif-containing protein 10-like K12002 TRIM10; tripartite motif-containing protein 10
D 121016695 TRIM11; E3 ubiquitin-protein ligase TRIM11 K10650 TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]
D 121012929 TRIM13; E3 ubiquitin-protein ligase TRIM13 K12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]
D 121034711 TRIM14; tripartite motif-containing protein 14 isoform X1 K12004 TRIM14; tripartite motif-containing protein 14
D 121015863 TRIM16; tripartite motif-containing protein 16 isoform X1 K12006 TRIM16; tripartite motif-containing protein 16 [EC:2.3.2.27]
D 121016694 TRIM17; E3 ubiquitin-protein ligase TRIM17 isoform X1 K12007 TRIM17; tripartite motif-containing protein 17 [EC:2.3.2.27]
D 121025179 MID1; E3 ubiquitin-protein ligase Midline-1 isoform X1 K08285 TRIM18; midline 1 [EC:2.3.2.27]
D 121039210 TRIM21; E3 ubiquitin-protein ligase TRIM21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
D 121015244 TRIM23; E3 ubiquitin-protein ligase TRIM23 isoform X1 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 121028273 TRIM24; transcription intermediary factor 1-alpha isoform X1 K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
D 121017898 E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 121044747 TRIM25; E3 ubiquitin/ISG15 ligase TRIM25 isoform X1 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 121018377 tripartite motif-containing protein 26 K12008 TRIM26; tripartite motif-containing protein 26
D 121018337 TRIM27; zinc finger protein RFP K12009 TRIM27; tripartite motif-containing protein 27 [EC:2.3.2.27]
D 121023366 TRIM28; transcription intermediary factor 1-beta K08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]
D 121035529 TRIM29; tripartite motif-containing protein 29 K12010 TRIM29; tripartite motif-containing protein 29
D 121034893 TRIM32; E3 ubiquitin-protein ligase TRIM32 K10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]
D 121027729 TRIM33; E3 ubiquitin-protein ligase TRIM33 isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 121022095 TRIM35; E3 ubiquitin-protein ligase TRIM35 isoform X1 K12012 TRIM35; tripartite motif-containing protein 35
D 121010547 TRIM36; E3 ubiquitin-protein ligase TRIM36 K12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
D 121044708 TRIM37; E3 ubiquitin-protein ligase TRIM37 isoform X1 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 121020318 TRIM38; E3 ubiquitin-protein ligase TRIM38 isoform X1 K12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]
D 121023120 E3 ubiquitin-protein ligase TRIM39 isoform X1 K12015 TRIM39; tripartite motif-containing protein 39 / bloodthirsty-related gene family protein [EC:2.3.2.27]
D 121016640 TRIM41; E3 ubiquitin-protein ligase TRIM41 isoform X1 K12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]
D 121033745 TRIM42; tripartite motif-containing protein 42 K12018 TRIM42; tripartite motif-containing protein 42
D 121039183 tripartite motif-containing protein 43-like K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 121039525 tripartite motif-containing protein 64-like K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 121039526 tripartite motif-containing protein 77-like K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 121043543 TRIM44; tripartite motif-containing protein 44 isoform X1 K12020 TRIM44; tripartite motif-containing protein 44
D 121027779 TRIM45; tripartite motif-containing protein 45 isoform X1 K12021 TRIM45; tripartite motif-containing protein 45
D 121024525 tripartite motif-containing protein 46-like K12022 TRIM46; tripartite motif-containing protein 46
D 121018127 TRIM47; E3 ubiquitin-protein ligase TRIM47 K12023 TRIM47; tripartite motif-containing protein 47
D 121017719 TRIM50; E3 ubiquitin-protein ligase TRIM50 isoform X1 K12024 TRIM50_73_74; tripartite motif-containing protein 50/73/74
D 121016644 TRIM52; E3 ubiquitin-protein ligase TRIM52 isoform X1 K12025 TRIM52; tripartite motif-containing protein 52
D 121044259 TRIM54; tripartite motif-containing protein 54 K10653 TRIM54; tripartite motif-containing protein 54
D 121038172 TRIM55; tripartite motif-containing protein 55 isoform X1 K10654 TRIM55; tripartite motif-containing protein 55
D 121017651 TRIM56; E3 ubiquitin-protein ligase TRIM56 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 121023604 TRIM58; E3 ubiquitin-protein ligase TRIM58 K12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]
D 121033920 TRIM59; tripartite motif-containing protein 59 K12028 TRIM59; tripartite motif-containing protein 59
D 121013661 tripartite motif-containing protein 60-like K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 121027592 tripartite motif-containing protein 60-like K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 121036357 TRIM61; LOW QUALITY PROTEIN: putative tripartite motif-containing protein 61 K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 121025738 TRIM62; E3 ubiquitin-protein ligase TRIM62 isoform X1 K12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]
D 121023652 TRIM63; E3 ubiquitin-protein ligase TRIM63 isoform X1 K10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]
D 121017934 TRIM65; tripartite motif-containing protein 65 isoform X1 K12031 TRIM65; tripartite motif-containing protein 65
D 121018255 TRIM66; tripartite motif-containing protein 66 isoform X1 K12032 TRIM66; tripartite motif-containing protein 66
D 121039196 TRIM68; E3 ubiquitin-protein ligase TRIM68 isoform X1 K12033 TRIM68; tripartite motif-containing protein 68 [EC:2.3.2.27]
D 121041628 TRIM69; E3 ubiquitin-protein ligase TRIM69 isoform X1 K12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]
D 121033609 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 121022158 TRIM72; tripartite motif-containing protein 72 K12036 TRIM72; tripartite motif-containing protein 72
D 121026576 putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
D 121026577 putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
D 121026588 putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
D 121035007 putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
D 121035148 putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
C UBR box proteins
D 121041582 UBR1; E3 ubiquitin-protein ligase UBR1 K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D 121029457 UBR2; E3 ubiquitin-protein ligase UBR2 isoform X1 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 121030676 UBR3; E3 ubiquitin-protein ligase UBR3 isoform X1 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 121022054 UBR4; E3 ubiquitin-protein ligase UBR4 isoform X1 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 121032221 UBR7; putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 121045328 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 121036450 AIRE; autoimmune regulator K10603 AIRE; autoimmune regulator
D 121019489 BFAR; bifunctional apoptosis regulator isoform X1 K15684 BFAR; bifunctional apoptosis regulator
D 121020751 baculoviral IAP repeat-containing protein 3-like K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 121020801 BIRC2; baculoviral IAP repeat-containing protein 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 121025478 E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 121020092 BIRC7; baculoviral IAP repeat-containing protein 7 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 121010333 BRCA1-associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 121045059 BRCA1; breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 121028893 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 121031396 CCNB1IP1; E3 ubiquitin-protein ligase CCNB1IP1 K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D 121022743 CHFR; E3 ubiquitin-protein ligase CHFR K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 121028288 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 121015648 DCST1; E3 ubiquitin-protein ligase DCST1 isoform X1 K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 121010118 DTX1; E3 ubiquitin-protein ligase DTX1 K06058 DTX; deltex [EC:2.3.2.27]
D 121017695 DTX2; probable E3 ubiquitin-protein ligase DTX2 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 121036327 DTX3L; E3 ubiquitin-protein ligase DTX3L K06058 DTX; deltex [EC:2.3.2.27]
D 121040870 DTX3; probable E3 ubiquitin-protein ligase DTX3 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 121043380 DTX4; E3 ubiquitin-protein ligase DTX4 K06058 DTX; deltex [EC:2.3.2.27]
D 121036199 DZIP3; E3 ubiquitin-protein ligase DZIP3 isoform X1 K10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]
D 121016264 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 121019176 KCMF1; E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 121035020 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 isoform X1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 121036034 LTN1; E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 121015675 MAP3K1; mitogen-activated protein kinase kinase kinase 1 isoform X1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 121015461 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 121032917 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C isoform X1 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 121042302 MEX3B; RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 121019576 MGRN1; E3 ubiquitin-protein ligase MGRN1 isoform X1 K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
D 121019230 MIB2; E3 ubiquitin-protein ligase MIB2 isoform X1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 121033101 MIB1; E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 121028247 MKRN1; E3 ubiquitin-protein ligase makorin-1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 121029337 E3 ubiquitin-protein ligase makorin-1-like isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 121041242 MKRN2; probable E3 ubiquitin-protein ligase makorin-2 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 121042524 MKRN3; probable E3 ubiquitin-protein ligase makorin-3 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 121022358 MUL1; mitochondrial ubiquitin ligase activator of NFKB 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 121037827 MYCBP2; E3 ubiquitin-protein ligase MYCBP2 isoform X1 K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 121020612 E3 ubiquitin-protein ligase MYLIP isoform X1 K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 121037473 NEURL1; E3 ubiquitin-protein ligase NEURL1 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 121041780 NEURL1B; E3 ubiquitin-protein ligase NEURL1B K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 121044400 NEURL3; E3 ubiquitin-protein ligase NEURL3 K15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]
D 121020465 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
D 121037822 OBI1; ORC ubiquitin ligase 1 K24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
D 121025236 PJA1; E3 ubiquitin-protein ligase Praja-1 isoform X1 K10633 PJA1; E3 ubiquitin-protein ligase Praja1 [EC:2.3.2.27]
D 121012173 PJA2; E3 ubiquitin-protein ligase Praja-2 K10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]
D 121041308 RAD18; E3 ubiquitin-protein ligase RAD18 isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 121043533 RAG1; V(D)J recombination-activating protein 1 K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
D 121034203 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 isoform X1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 121011925 RC3H1; roquin-1 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 121034955 RC3H2; roquin-2 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 121011907 COP1; E3 ubiquitin-protein ligase COP1 isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
D 121009792 RFWD3; E3 ubiquitin-protein ligase RFWD3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 121011842 RNF2; E3 ubiquitin-protein ligase RING2 isoform X1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 121029273 RING1; E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 121039317 RNF4; E3 ubiquitin-protein ligase RNF4 isoform X1 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 121041627 E3 ubiquitin-protein ligase RNF4-like K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 121022323 RNF5; E3 ubiquitin-protein ligase RNF5 isoform X1 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 121022672 RNF185; E3 ubiquitin-protein ligase RNF185 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 121012756 RNF6; E3 ubiquitin-protein ligase RNF6 K22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]
D 121029379 RNF8; E3 ubiquitin-protein ligase RNF8 isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 121010224 RNF10; RING finger protein 10 isoform X1 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 121027112 RNF11; RING finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 121024924 RLIM; E3 ubiquitin-protein ligase RLIM K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 121025996 E3 ubiquitin-protein ligase RLIM-like K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 121033824 RNF13; E3 ubiquitin-protein ligase RNF13 isoform X1 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 121031074 RNF25; E3 ubiquitin-protein ligase RNF25 isoform X1 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 121035514 RNF26; E3 ubiquitin-protein ligase RNF26 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 121011359 RNF44; RING finger protein 44 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 121034673 RNF38; E3 ubiquitin-protein ligase RNF38 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 121040932 RNF41; E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 121044723 RNF43; E3 ubiquitin-protein ligase RNF43 K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
D 121044493 E3 ubiquitin-protein ligase RNF103 isoform X1 K15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
D 121041776 RNF111; E3 ubiquitin-protein ligase Arkadia isoform X1 K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D 121015828 RNF112; RING finger protein 112 isoform X1 K25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]
D 121020113 RNF114; E3 ubiquitin-protein ligase RNF114 K15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]
D 121021799 RNF115; E3 ubiquitin-protein ligase RNF115 isoform X1 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 121024334 RNF126; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 121028352 RNF175; RING finger protein 175 isoform X1 K15698 RNF121_175; RING finger protein 121/175
D 121039220 RNF121; RING finger protein 121 isoform X1 K15698 RNF121_175; RING finger protein 121/175
D 121021666 RNF122; RING finger protein 122 isoform X1 K15699 RNF122; RING finger protein 122
D 121011203 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 121033034 RNF125; E3 ubiquitin-protein ligase RNF125 K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
D 121025702 RNF128; E3 ubiquitin-protein ligase RNF128 isoform X1 K10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
D 121010834 RNF130; E3 ubiquitin-protein ligase RNF130 K15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]
D 121028415 RNF133; E3 ubiquitin-protein ligase RNF133 K15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]
D 121017154 RNF135; E3 ubiquitin-protein ligase RNF135 K16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]
D 121033032 RNF138; E3 ubiquitin-protein ligase RNF138 isoform X1 K10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]
D 121042953 RNF139; E3 ubiquitin-protein ligase RNF139 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 121010097 RNF145; RING finger protein 145 K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 121030023 RNF146; E3 ubiquitin-protein ligase RNF146 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 121016429 RNF149; E3 ubiquitin-protein ligase RNF149 isoform X1 K15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]
D 121032856 RNF152; E3 ubiquitin-protein ligase RNF152 K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
D 121017947 RNF157; E3 ubiquitin ligase RNF157 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 121032973 RNF165; E3 ubiquitin-protein ligase RNF165 K17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]
D 121009925 RNF166; E3 ubiquitin-protein ligase RNF166 K17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
D 121016062 RNF167; E3 ubiquitin-protein ligase RNF167 isoform X1 K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
D 121040867 E3 ubiquitin-protein ligase RNF167-like K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
D 121011149 RNF170; E3 ubiquitin-protein ligase RNF170 isoform X1 K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 121015317 RNF180; E3 ubiquitin-protein ligase RNF180 isoform X1 K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 121019163 RNF181; E3 ubiquitin-protein ligase RNF181 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 121020456 RNF182; E3 ubiquitin-protein ligase RNF182 K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 121018145 RNF186; E3 ubiquitin-protein ligase RNF186 K25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]
D 121016664 RNF187; E3 ubiquitin-protein ligase RNF187 K15709 RNF187; E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27]
D 121018026 RNF213; E3 ubiquitin-protein ligase RNF213 isoform X1 K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 121027005 RNF220; E3 ubiquitin-protein ligase RNF220 isoform X1 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 121044692 RNFT1; E3 ubiquitin-protein ligase RNFT1 isoform X1 K22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]
D 121010279 RNFT2; RING finger and transmembrane domain-containing protein 2 isoform X1 K28516 RNFT2; E3 ubiquitin-protein ligase RNFT2
D 121023875 SART1; U4/U6.U5 tri-snRNP-associated protein 1 isoform X1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 121013349 SHPRH; E3 ubiquitin-protein ligase SHPRH isoform X1 K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 121016282 SH3RF2; E3 ubiquitin-protein ligase SH3RF2 isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 121016491 SH3RF3; E3 ubiquitin-protein ligase SH3RF3 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 121027420 SH3RF1; E3 ubiquitin-protein ligase SH3RF1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 121033809 HLTF; helicase-like transcription factor isoform X1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 121023712 SYVN1; E3 ubiquitin-protein ligase synoviolin isoform X1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 121039502 TMEM129; E3 ubiquitin-protein ligase TM129 isoform X1 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 121034556 TOPORS; E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 121011213 E3 ubiquitin-protein ligase TRAIP isoform X1 K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 121035946 TTC3; E3 ubiquitin-protein ligase TTC3 isoform X1 K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
D 121021410 UHRF1; E3 ubiquitin-protein ligase UHRF1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 121020826 UHRF2; E3 ubiquitin-protein ligase UHRF2 isoform X1 K15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]
D 121019729 UNKL; putative E3 ubiquitin-protein ligase UNKL K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 121019335 ZNF598; E3 ubiquitin-protein ligase ZNF598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 121043389 ZFP91; E3 ubiquitin-protein ligase ZFP91 isoform X1 K25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]
D 121009796 ZNRF1; E3 ubiquitin-protein ligase ZNRF1 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 121022616 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 isoform X1 K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
D 121021487 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 K15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]
D 121030804 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 isoform X1 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
B Atypical E3
C 121010705 JADE2; E3 ubiquitin-protein ligase Jade-2 isoform X1 K22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]
C 121019676 E4F1; transcription factor E4F1 isoform X1 K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
C 121022500 NSMCE1; non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 121018640 IRF2BP1; interferon regulatory factor 2-binding protein 1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
C 121032094 IRF2BPL; probable E3 ubiquitin-protein ligase IRF2BPL isoform X1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 121034556 TOPORS; E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 121016484 RANBP2; E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 121041891 PIAS1; E3 SUMO-protein ligase PIAS1 isoform X1 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 121032962 PIAS2; E3 SUMO-protein ligase PIAS2 isoform X1 K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
C 121021796 PIAS3; E3 SUMO-protein ligase PIAS3 isoform X1 K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
C 121021405 PIAS4; E3 SUMO-protein ligase PIAS4 K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
C 121024730 dual specificity protein phosphatase 8-like K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
C 121041973 PML; protein PML isoform X1 K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
C 121018016 CBX4; E3 SUMO-protein ligase CBX4 K11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]
C 121042964 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 121031512 RNF212B; RING finger protein 212B isoform X1 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 121039632 RNF212; probable E3 SUMO-protein ligase RNF212 isoform X1 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 121020220 ZBED1; E3 SUMO-protein ligase ZBED1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 121029616 ZNF451; E3 SUMO-protein ligase ZNF451 isoform X1 K25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]
C 121032760 HERC5; E3 ISG15--protein ligase HERC5 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 121032765 HERC6; probable E3 ubiquitin-protein ligase HERC6 isoform X1 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 121029800 UFL1; E3 UFM1-protein ligase 1 isoform X1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 121034049 DCUN1D1; DCN1-like protein 1 isoform X1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 121037677 DCUN1D2; DCN1-like protein 2 isoform X1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 121019425 DCUN1D3; DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 121020780 DCUN1D5; DCN1-like protein 5 isoform X1 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 121035931 DCUN1D4; DCN1-like protein 4 isoform X1 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit type E3
C SCF complex
D Ring finger protein
E 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 121028153 CUL1; cullin-1 isoform X1 K03347 CUL1; cullin 1
D Adaptor protein
E 121010703 SKP1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 121010989 FBXW11; F-box/WD repeat-containing protein 11 isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 121037135 BTRC; F-box/WD repeat-containing protein 1A isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 121014127 LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 2-like K10261 FBXW2; F-box and WD-40 domain protein 2
E 121034905 FBXW2; F-box/WD repeat-containing protein 2 isoform X1 K10261 FBXW2; F-box and WD-40 domain protein 2
E 121037137 FBXW4; F-box/WD repeat-containing protein 4 isoform X1 K10262 FBXW4; F-box and WD-40 domain protein 4
E 121020259 FBXW5; F-box/WD repeat-containing protein 5 isoform X1 K10263 FBXW5; F-box and WD-40 domain protein 5
E 121028525 FBXW7; F-box/WD repeat-containing protein 7 isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 121010276 FBXW8; F-box/WD repeat-containing protein 8 isoform X1 K10264 FBXW8; F-box and WD-40 domain protein 8
E 121014028 FBXW9; F-box/WD repeat-containing protein 9 isoform X1 K10265 FBXW9; F-box and WD-40 domain protein 9
E 121015864 CDRT1; CMT1A duplicated region transcript 1 protein isoform X1 K10266 FBXW10; F-box and WD-40 domain protein 10
E 121011152 FBXW12; F-box/WD repeat-containing protein 12 isoform X1 K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 121013761 LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 12-like K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 121043524 SKP2; S-phase kinase-associated protein 2 isoform X1 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 121033422 FBXL2; F-box/LRR-repeat protein 2 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 121044904 FBXL20; F-box/LRR-repeat protein 20 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 121037830 FBXL3; F-box/LRR-repeat protein 3 isoform X1 K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 121029814 FBXL4; F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 121038169 FBXL5; F-box/LRR-repeat protein 5 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 121043145 FBXL6; F-box/LRR-repeat protein 6 isoform X1 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 121042846 FBXL7; F-box/LRR-repeat protein 7 isoform X1 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 121045447 FBXL8; F-box/LRR-repeat protein 8 K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 121045439 LRRC29; leucine-rich repeat-containing protein 29 isoform X1 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 121010451 KDM2B; lysine-specific demethylase 2B isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 121023707 KDM2A; lysine-specific demethylase 2A isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 121013947 FBXL12; F-box/LRR-repeat protein 12 isoform X1 K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 121028834 FBXL13; dynein regulatory complex subunit 6 K10279 FBXL13; dynein regulatory complex subunit 6
E 121022121 FBXL14; F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 121037161 FBXL15; F-box/LRR-repeat protein 15 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 121019764 FBXL16; F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 121041837 FBXL17; F-box/LRR-repeat protein 17 K10283 FBXL17; F-box and leucine-rich repeat protein 17
E 121017532 FBXL18; F-box/LRR-repeat protein 18 isoform X1 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 121022170 FBXL19; F-box/LRR-repeat protein 19 isoform X1 K10285 FBXL19; F-box and leucine-rich repeat protein 19
E 121010734 F-box/LRR-repeat protein 21 isoform X1 K10287 FBXL21; F-box and leucine-rich repeat protein 21
E 121041812 FBXL22; F-box and leucine-rich protein 22 isoform X1 K10288 FBXL22; F-box and leucine-rich repeat protein 22
E 121019672 CCNF; cyclin-F isoform X1 K10289 CCNF; F-box protein 1 (cyclin F)
E 121021089 FBXO2; F-box only protein 2 isoform X1 K10099 FBXO2; F-box protein 2
E 121043576 FBXO3; F-box only protein 3 K10290 FBXO3; F-box protein 3
E 121044203 FBXO4; F-box only protein 4 isoform X1 K10291 FBXO4; F-box protein 4
E 121013293 FBXO5; F-box only protein 5 isoform X1 K10292 FBXO5; F-box protein 5
E 121021130 FBXO6; F-box only protein 6 K10100 FBXO6; F-box protein 6
E 121040451 FBXO7; F-box only protein 7 isoform X1 K10293 FBXO7; F-box protein 7
E 121027130 FBXO8; F-box only protein 8 K10294 FBXO8; F-box protein 8
E 121029590 FBXO9; F-box only protein 9 K10295 FBXO9; F-box protein 9
E 121034685 FBXO10; F-box only protein 10 isoform X1 K10296 FBXO10; F-box protein 10
E 121016313 FBXO11; F-box only protein 11 K10297 FBXO11; F-box protein 11
E 121032798 FBXO15; F-box only protein 15 isoform X1 K10298 FBXO15; F-box protein 15
E 121024189 FBXO16; F-box only protein 16 isoform X1 K10299 FBXO16; F-box protein 16
E 121011482 FBXO17; F-box only protein 17 K10101 FBXO17; F-box protein 17
E 121014859 FBH1; F-box DNA helicase 1 isoform X1 K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 121037841 LMO7; LIM domain only protein 7 isoform X1 K06084 LMO7; F-box protein 20
E 121010273 FBXO21; F-box only protein 21 isoform X1 K10301 FBXO21; F-box protein 21
E 121042047 FBXO22; F-box only protein 22 isoform X1 K10302 FBXO22; F-box protein 22
E 121011503 TSPAN17; tetraspanin-17 isoform X1 K10303 FBXO23; F-box protein 23
E 121017632 FBXO24; F-box only protein 24 isoform X1 K10304 FBXO24; F-box protein 24
E 121039579 FBXO25; F-box only protein 25 isoform X1 K10305 FBXO25_32; F-box protein 25/32
E 121042942 FBXO32; F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E 121011481 FBXO27; F-box only protein 27 isoform X1 K10102 FBXO27; F-box protein 27
E 121015011 FBXO28; LOW QUALITY PROTEIN: F-box only protein 28 K10306 FBXO28; F-box protein 28
E 121013350 FBXO30; F-box only protein 30 K10307 FBXO30; F-box protein 30
E 121009906 FBXO31; F-box only protein 31 K10308 FBXO31; F-box protein 31
E 121031689 FBXO33; F-box only protein 33 isoform X1 K10310 FBXO33; F-box protein 33
E 121031801 FBXO34; F-box only protein 34 K10311 FBXO34; F-box protein 34
E 121014466 FBXO36; F-box only protein 36 isoform X1 K10312 FBXO36; F-box protein 36
E 121044683 FBXO38; F-box only protein 38 isoform X1 K10313 FBXO38; F-box protein 38
E 121016090 FBXO39; F-box only protein 39 K10314 FBXO39; F-box protein 39
E 121036305 FBXO40; F-box only protein 40 K10315 FBXO40; F-box protein 40
E 121019258 FBXO41; F-box only protein 41 K10316 FBXO41; F-box protein 41
E 121021753 FBXO42; F-box only protein 42 isoform X1 K10317 FBXO42; F-box protein 42
E 121043254 FBXO43; LOW QUALITY PROTEIN: F-box only protein 43 K10318 FBXO43; F-box protein 43
E 121021099 FBXO44; F-box only protein 44 isoform X1 K10103 FBXO44; F-box protein 44
E 121036390 FBXO45; F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
E 121018629 FBXO46; F-box only protein 46 K10320 FBXO46; F-box protein 46
E 121044896 FBXO47; F-box only protein 47 K10321 FBXO47; F-box protein 47
E 121019072 FBXO48; F-box only protein 48 K27313 FBXO48; F-box protein 48
C Cul2 complex
D Ring finger protein
E 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 121014613 CUL2; cullin-2 K03870 CUL2; cullin 2
D Adoptor protein
E 121013126 elongin-C-like isoform X1 K03872 ELOC; elongin-C
E 121038113 ELOC; elongin-C isoform X1 K03872 ELOC; elongin-C
E 121019653 ELOB; elongin-B K03873 ELOB; elongin-B
E 121027481 elongin-B-like K03873 ELOB; elongin-B
E 121043887 elongin-B-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 121041270 VHL; von Hippel-Lindau disease tumor suppressor isoform X1 K03871 VHL; von Hippel-Lindau disease tumor supressor
E 121031721 LRR1; leucine-rich repeat protein 1 isoform X1 K10348 LRR1; LRR-repeat protein 1
E 121010552 FEM1C; protein fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 121021516 FEM1A; protein fem-1 homolog A K25805 FEM1A_C; protein fem-1 homolog A/C
E 121041894 FEM1B; protein fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 121044672 APPBP2; amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 121031730 KLHDC2; kelch domain-containing protein 2 K25807 KLHDC2; kelch domain-containing protein 2
E 121029474 KLHDC3; kelch domain-containing protein 3 isoform X1 K25808 KLHDC3; kelch domain-containing protein 3
E 121028344 KLHDC10; kelch domain-containing protein 10 isoform X1 K25809 KLHDC10; kelch domain-containing protein 10
E 121027135 ZYG11B; protein zyg-11 homolog B K10350 ZYG11; Zyg-11 protein
E 121027136 ZYG11A; protein zyg-11 homolog A K10350 ZYG11; Zyg-11 protein
E 121035074 ZER1; protein zer-1 homolog isoform X1 K10350 ZYG11; Zyg-11 protein
E 121036644 ZSWIM8; zinc finger SWIM domain-containing protein 8 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
E 121010130 PRAME; melanoma antigen preferentially expressed in tumors isoform X1 K28155 PRAME; melanoma antigen preferentially expressed in tumors
C Cul3 complex
D Ring finger protein
E 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 121014490 CUL3; cullin-3 isoform X1 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 121036867 KLHL5; kelch-like protein 5 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 121037863 KLHL1; kelch-like protein 1 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 121010750 KLHL3; kelch-like protein 3 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 121027551 KLHL2; kelch-like protein 2 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 121034060 KLHL6; kelch-like protein 6 isoform X1 K10444 KLHL6; kelch-like protein 6
E 121028627 KLHL7; kelch-like protein 7 isoform X1 K10445 KLHL7; kelch-like protein 7
E 121032925 KLHL8; kelch-like protein 8 isoform X1 K10446 KLHL8; kelch-like protein 8
E 121025464 KLHL13; kelch-like protein 13 isoform X1 K10447 KLHL9_13; kelch-like protein 9/13
E 121034517 KLHL9; kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 121045004 KLHL10; kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 121045003 KLHL11; kelch-like protein 11 K10449 KLHL11; kelch-like protein 11
E 121021589 KLHL12; kelch-like protein 12 isoform X1 K10450 KLHL12; kelch-like protein 12
E 121033027 KLHL14; kelch-like protein 14 K10451 KLHL14; kelch-like protein 14
E 121025926 KLHL15; kelch-like protein 15 K10452 KLHL15; kelch-like protein 15
E 121009843 GAN; gigaxonin K10453 KLHL16; kelch-like protein 16 (gigaxonin)
E 121018776 KLHL17; kelch-like protein 17 isoform X1 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 121011133 KLHL18; kelch-like protein 18 isoform X1 K10455 KLHL18; kelch-like protein 18
E 121013978 KEAP1; kelch-like ECH-associated protein 1 K10456 KLHL19; kelch-like protein 19
E 121011930 KLHL20; kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 121020059 KLHL21; kelch-like protein 21 K10458 KLHL21; kelch-like protein 21
E 121023318 KLHL22; kelch-like protein 22 K10459 KLHL22; kelch-like protein 22
E 121030673 KLHL23; kelch-like protein 23 K10460 KLHL23; kelch-like protein 23
E 121034062 KLHL24; kelch-like protein 24 isoform X1 K10461 KLHL24_35; kelch-like protein 24/35
E 121039290 KLHL35; kelch-like protein 35 K10461 KLHL24_35; kelch-like protein 24/35
E 121014515 ENC1; ectoderm-neural cortex protein 1 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 121042427 KLHL25; kelch-like protein 25 isoform X1 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 121011030 KLHL26; kelch-like protein 26 isoform X1 K10463 KLHL26; kelch-like protein 26
E 121027042 actin-binding protein IPP isoform X1 K13956 IPP; actin-binding protein IPP
E 121031707 KLHL28; kelch-like protein 28 isoform X1 K10464 KLHL28; kelch-like protein 28
E 121044181 KLHL29; kelch-like protein 29 isoform X1 K10465 KLHL29; kelch-like protein 29
E 121014361 KLHL30; kelch-like protein 30 K10466 KLHL30; kelch-like protein 30
E 121029595 KLHL31; kelch-like protein 31 K10467 KLHL31; kelch-like protein 31
E 121029808 KLHL32; kelch-like protein 32 isoform X1 K10468 KLHL32; kelch-like protein 32
E 121031399 KLHL33; kelch-like protein 33 K13957 KLHL33; kelch-like protein 33
E 121024086 KLHL34; kelch-like protein 34 K10469 KLHL34; kelch-like protein 34
E 121042943 KLHL38; kelch-like protein 38 K13959 KLHL38; kelch-like protein 38
E 121038772 KLHL42; kelch-like protein 42 K27973 KLHL42; kelch-like protein 42
E 121028513 KBTBD2; kelch repeat and BTB domain-containing protein 2 K10470 KBTBD2; kelch repeat and BTB domain-containing protein 2
E 121020767 KBTBD3; kelch repeat and BTB domain-containing protein 3 K10471 KBTBD3; kelch repeat and BTB domain-containing protein 3
E 121043433 KBTBD4; kelch repeat and BTB domain-containing protein 4 K10472 KBTBD4; kelch repeat and BTB domain-containing protein 4
E 121030666 KLHL41; kelch-like protein 41 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 121033528 KLHL40; kelch-like protein 40 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 121013023 KBTBD7; kelch repeat and BTB domain-containing protein 7 K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E 121013025 kelch repeat and BTB domain-containing protein 6 K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E 121016749 KBTBD8; kelch repeat and BTB domain-containing protein 8 isoform X1 K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E 121040001 KBTBD11; kelch repeat and BTB domain-containing protein 11 K10476 KBTBD11; kelch repeat and BTB domain-containing protein 11
E 121026326 kelch repeat and BTB domain-containing protein 12 K21912 KBTBD12; kelch repeat and BTB domain-containing protein 12
E 121026327 kelch repeat and BTB domain-containing protein 12 K21912 KBTBD12; kelch repeat and BTB domain-containing protein 12
E 121041840 KBTBD13; kelch repeat and BTB domain-containing protein 13 K21913 KBTBD13; kelch repeat and BTB domain-containing protein 13
E 121042320 BTBD1; BTB/POZ domain-containing protein 1 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 121012497 BTBD3; BTB/POZ domain-containing protein 3 isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 121032373 BTBD6; BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 121032220 BTBD7; BTB/POZ domain-containing protein 7 isoform X1 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 121027474 BTBD8; BTB/POZ domain-containing protein 8 isoform X1 K10480 BTBD8; BTB/POZ domain-containing protein 8
E 121029392 BTBD9; BTB/POZ domain-containing protein 9 isoform X1 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 121018191 BTBD10; BTB/POZ domain-containing protein 10 isoform X1 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 121040463 BTBD11; ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform X1 K10483 BTBD11; BTB/POZ domain-containing protein 11
E 121019821 SLX4; structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 121019298 GMCL1; germ cell-less protein-like 1 K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 121022856 NACC2; nucleus accumbens-associated protein 2 isoform X1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 121024456 NACC1; nucleus accumbens-associated protein 1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 121037321 BTBD16; BTB/POZ domain-containing protein 16 isoform X1 K10487 BTBD16; BTB/POZ domain-containing protein 16
E 121031893 ZBTB1; zinc finger and BTB domain-containing protein 1 isoform X1 K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
E 121013310 ZBTB2; zinc finger and BTB domain-containing protein 2 isoform X1 K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
E 121023823 ZBTB3; zinc finger and BTB domain-containing protein 3 K10490 ZBTB3; zinc finger and BTB domain-containing protein 3
E 121015997 ZBTB4; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 4 K10491 ZBTB4; zinc finger and BTB domain-containing protein 4
E 121034682 ZBTB5; zinc finger and BTB domain-containing protein 5 K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
E 121034959 ZBTB6; zinc finger and BTB domain-containing protein 6 isoform X1 K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
E 121015651 ZBTB7B; zinc finger and BTB domain-containing protein 7B K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 121021541 ZBTB7A; zinc finger and BTB domain-containing protein 7A isoform X1 K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 121032953 ZBTB7C; zinc finger and BTB domain-containing protein 7C K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 121025472 ZBTB8B; zinc finger and BTB domain-containing protein 8B K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 121025485 ZBTB8A; zinc finger and BTB domain-containing protein 8A isoform X1 K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 121029290 ZBTB9; zinc finger and BTB domain-containing protein 9 K10496 ZBTB9; zinc finger and BTB domain-containing protein 9
E 121038075 ZBTB10; zinc finger and BTB domain-containing protein 10 isoform X1 K10497 ZBTB10; zinc finger and BTB domain-containing protein 10
E 121036174 ZBTB11; zinc finger and BTB domain-containing protein 11 isoform X1 K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
E 121022339 ZBTB12; zinc finger and BTB domain-containing protein 12 K10499 ZBTB12; zinc finger and BTB domain-containing protein 12
E 121035410 ZBTB16; zinc finger and BTB domain-containing protein 16 K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
E 121021655 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1 K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 121036470 ZBTB20; zinc finger and BTB domain-containing protein 20 isoform X1 K10501 ZBTB20; zinc finger and BTB domain-containing protein 20
E 121029277 ZBTB22; zinc finger and BTB domain-containing protein 22 K10502 ZBTB22; zinc finger and BTB domain-containing protein 22
E 121029883 ZBTB24; zinc finger and BTB domain-containing protein 24 isoform X1 K10503 ZBTB24; zinc finger and BTB domain-containing protein 24
E 121031896 ZBTB25; zinc finger and BTB domain-containing protein 25 isoform X1 K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
E 121034958 ZBTB26; zinc finger and BTB domain-containing protein 26 K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E 121011551 ZBTB32; zinc finger and BTB domain-containing protein 32 isoform X1 K10506 ZBTB32; zinc finger and BTB domain-containing protein 32
E 121025488 ZBTB33; transcriptional regulator Kaiso K10507 ZBTB33; zinc finger and BTB domain-containing protein 33
E 121035006 ZBTB34; zinc finger and BTB domain-containing protein 34 isoform X1 K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
E 121011927 ZBTB37; zinc finger and BTB domain-containing protein 37 isoform X1 K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
E 121033753 ZBTB38; zinc finger and BTB domain-containing protein 38 isoform X1 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E 121040896 ZBTB39; zinc finger and BTB domain-containing protein 39 K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
E 121022851 ZBTB40; zinc finger and BTB domain-containing protein 40 isoform X1 K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
E 121022428 ZBTB41; zinc finger and BTB domain-containing protein 41 K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
E 121035009 ZBTB43; zinc finger and BTB domain-containing protein 43 K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
E 121035643 ZBTB44; zinc finger and BTB domain-containing protein 44 isoform X1 K10515 ZBTB44; zinc finger and BTB domain-containing protein 44
E 121023402 ZBTB45; zinc finger and BTB domain-containing protein 45 isoform X1 K10516 ZBTB45; zinc finger and BTB domain-containing protein 45
E 121020053 ZBTB46; zinc finger and BTB domain-containing protein 46 K10517 ZBTB46; zinc finger and BTB domain-containing protein 46
E 121033521 ZBTB47; zinc finger and BTB domain-containing protein 47 isoform X1 K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
E 121020047 ZBTB48; telomere zinc finger-associated protein K10519 ZBTB48; zinc finger and BTB domain-containing protein 48
E 121022292 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1 K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 121043562 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2 isoform X1 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 121036669 RHOBTB1; rho-related BTB domain-containing protein 1 isoform X1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 121039860 RHOBTB2; rho-related BTB domain-containing protein 2 isoform X1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 121012849 RHOBTB3; rho-related BTB domain-containing protein 3 K07869 RHOBTB3; Rho-related BTB domain-containing protein 3
E 121017189 TNFAIP1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 121022223 KCTD13; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 121011617 KCTD15; BTB/POZ domain-containing protein KCTD15 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 121033065 KCTD1; BTB/POZ domain-containing protein KCTD1 isoform X1 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 121018125 KCTD2; BTB/POZ domain-containing protein KCTD2 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 121019664 KCTD5; BTB/POZ domain-containing protein KCTD5 isoform X1 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 121026682 BTB/POZ domain-containing protein KCTD17-like K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 121026684 BTB/POZ domain-containing protein KCTD17-like K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 121041010 KCTD17; BTB/POZ domain-containing protein KCTD17 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 121020912 KCTD3; BTB/POZ domain-containing protein KCTD3 isoform X1 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 121016791 KCTD6; BTB/POZ domain-containing protein KCTD6 K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 121017781 KCTD7; BTB/POZ domain-containing protein KCTD7 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 121039339 KCTD14; BTB/POZ domain-containing protein KCTD14 isoform X1 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 121016332 KCTD16; BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 121036331 KCTD8; BTB/POZ domain-containing protein KCTD8 isoform X1 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 121037837 KCTD12; BTB/POZ domain-containing protein KCTD12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 121039839 KCTD9; BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 121016021 KCTD11; BTB/POZ domain-containing protein KCTD11 K21920 KCTD11; BTB/POZ domain-containing protein KCTD11 [EC:2.3.2.27]
E 121030890 KCTD18; BTB/POZ domain-containing protein KCTD18 isoform X1 K21921 KCTD18; BTB/POZ domain-containing protein KCTD18
E 121039346 KCTD21; BTB/POZ domain-containing protein KCTD21 K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 121026230 DIABLO; diablo homolog, mitochondrial K10522 DIABLO; diablo
E 121030503 SPOPL; speckle-type POZ protein-like isoform X1 K10523 SPOP; speckle-type POZ protein
E 121044815 speckle-type POZ protein isoform X1 K10523 SPOP; speckle-type POZ protein
E 121023042 LZTR1; LOW QUALITY PROTEIN: leucine-zipper-like transcriptional regulator 1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 121025448 CUL4B; cullin-4B isoform X1 K10609 CUL4; cullin 4
E 121037644 CUL4A; cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 121043330 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 121043455 DDB2; DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2
E 121015458 ERCC8; DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8
E 121042417 DET1; DET1 homolog isoform X1 K10571 DET1; de-etiolated-1
E 121011907 COP1; E3 ubiquitin-protein ligase COP1 isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
E 121010978 DDA1; DET1- and DDB1-associated protein 1 isoform X1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 121041336 CRBN; protein cereblon isoform X1 K11793 CRBN; cereblon
E 121011793 torsin-1A-interacting protein 2 K11794 IFRG15; IFRG15 protein
E 121012276 short transient receptor potential channel 4-associated protein isoform X1 K11796 TRPC4AP; Trpc4-associated protein
E 121011256 DCAF1; DDB1- and CUL4-associated factor 1 isoform X1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 121011753 DTL; denticleless protein homolog isoform X1 K11790 DTL; denticleless
E 121032008 DCAF4; DDB1- and CUL4-associated factor 4 isoform X1 K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 121031966 DCAF5; DDB1- and CUL4-associated factor 5 isoform X1 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 121015069 DCAF6; DDB1- and CUL4-associated factor 6 isoform X1 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 121015253 DCAF7; DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 121015509 DCAF8; DDB1- and CUL4-associated factor 8 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 121026091 DDB1- and CUL4-associated factor 8-like K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 121023981 WDTC1; WD and tetratricopeptide repeats protein 1 isoform X1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 121034690 DCAF10; DDB1- and CUL4-associated factor 10 isoform X1 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 121031537 DCAF11; DDB1- and CUL4-associated factor 11 isoform X1 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 121024207 DCAF12L2; DDB1- and CUL4-associated factor 12-like protein 2 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 121024379 DDB1- and CUL4-associated factor 12-like protein 2 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 121034582 DCAF12; DDB1- and CUL4-associated factor 12 isoform X1 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 121042825 DCAF13; DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 121029693 PH-interacting protein isoform X1 K11797 PHIP; PH-interacting protein
E 121014081 DCAF15; DDB1- and CUL4-associated factor 15 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 121037842 DCAF16; DDB1- and CUL4-associated factor 16 K23626 DCAF16; DDB1- and CUL4-associated factor 16
E 121030687 DCAF17; DDB1- and CUL4-associated factor 17 isoform X1 K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 121025357 BRWD3; bromodomain and WD repeat-containing protein 3 isoform X1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 121035934 BRWD1; bromodomain and WD repeat-containing protein 1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 121015180 WDR26; WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
E 121043664 WDR70; WD repeat-containing protein 70 isoform X1 K24752 WDR70; WD repeat-containing protein 70
E 121041604 WDR76; WD repeat-containing protein 76 isoform X1 K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
E 121033758 RNF7; RING-box protein 2 isoform X1 K10611 RBX2; RING-box protein 2
D Cullin
E 121035307 CUL5; cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E 121013126 elongin-C-like isoform X1 K03872 ELOC; elongin-C
E 121038113 ELOC; elongin-C isoform X1 K03872 ELOC; elongin-C
E 121019653 ELOB; elongin-B K03873 ELOB; elongin-B
E 121027481 elongin-B-like K03873 ELOB; elongin-B
E 121043887 elongin-B-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 121011251 CISH; cytokine-inducible SH2-containing protein K04701 CISH; cytokine inducible SH2-containing protein
E 121019519 SOCS1; suppressor of cytokine signaling 1 K04694 SOCS1; suppressor of cytokine signaling 1
E 121040616 SOCS2; suppressor of cytokine signaling 2 K04695 SOCS2; suppressor of cytokine signaling 2
E 121024518 SOCS3; suppressor of cytokine signaling 3 K04696 SOCS3; suppressor of cytokine signaling 3
E 121031795 SOCS4; suppressor of cytokine signaling 4 K04697 SOCS4; suppressor of cytokine signaling 4
E 121016326 SOCS5; suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 121032807 SOCS6; suppressor of cytokine signaling 6 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 121044878 SOCS7; suppressor of cytokine signaling 7 isoform X1 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 121014352 ASB1; ankyrin repeat and SOCS box protein 1 isoform X1 K10323 ASB1; ankyrin repeat and SOCS box protein 1
E 121032230 ASB2; ankyrin repeat and SOCS box protein 2 isoform X1 K10324 ASB2; ankyrin repeat and SOCS box protein 2
E 121016293 ASB3; ankyrin repeat and SOCS box protein 3 isoform X1 K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 121028716 ASB4; ankyrin repeat and SOCS box protein 4 K10326 ASB4; ankyrin repeat and SOCS box protein 4
E 121039634 ASB5; ankyrin repeat and SOCS box protein 5 isoform X1 K10327 ASB5; ankyrin repeat and SOCS box protein 5
E 121035098 ASB6; ankyrin repeat and SOCS box protein 6 isoform X1 K10328 ASB6; ankyrin repeat and SOCS box protein 6
E 121042492 ASB7; ankyrin repeat and SOCS box protein 7 isoform X1 K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 121038658 ASB8; ankyrin repeat and SOCS box protein 8 isoform X1 K10330 ASB8; ankyrin repeat and SOCS box protein 8
E 121025624 ASB9; ankyrin repeat and SOCS box protein 9 isoform X1 K10331 ASB9; ankyrin repeat and SOCS box protein 9
E 121022907 ASB10; ankyrin repeat and SOCS box protein 10 isoform X1 K10332 ASB10; ankyrin repeat and SOCS box protein 10
E 121025625 ASB11; ankyrin repeat and SOCS box protein 11 isoform X1 K10333 ASB11; ankyrin repeat and SOCS box protein 11
E 121024891 ASB12; ankyrin repeat and SOCS box protein 12 isoform X1 K10334 ASB12; ankyrin repeat and SOCS box protein 12
E 121014865 ASB13; ankyrin repeat and SOCS box protein 13 K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 121016817 ASB14; ankyrin repeat and SOCS box protein 14 isoform X1 K10336 ASB14; ankyrin repeat and SOCS box protein 14
E 121028405 ASB15; ankyrin repeat and SOCS box protein 15 isoform X1 K10337 ASB15; ankyrin repeat and SOCS box protein 15
E 121045087 ASB16; ankyrin repeat and SOCS box protein 16 K10338 ASB16; ankyrin repeat and SOCS box protein 16
E 121027332 ASB17; ankyrin repeat and SOCS box protein 17 K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 121014257 ASB18; ankyrin repeat and SOCS box protein 18 K10340 ASB18; ankyrin repeat and SOCS box protein 18
E 121017171 WSB1; WD repeat and SOCS box-containing protein 1 isoform X1 K10341 WSB1; WD repeat and SOCS box-containing protein 1
E 121010265 WSB2; WD repeat and SOCS box-containing protein 2 K10342 WSB2; WD repeat and SOCS box-containing protein 2
E 121020508 SPSB1; SPRY domain-containing SOCS box protein 1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 121033748 SPSB4; SPRY domain-containing SOCS box protein 4 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 121022126 SPSB2; SPRY domain-containing SOCS box protein 2 K10344 SPSB2; SPRY domain-containing SOCS box protein 2
E 121019709 SPSB3; SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 121018109 RAB40B; ras-related protein Rab-40B isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 121019780 RAB40C; ras-related protein Rab-40C isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 121027057 LRRC41; leucine-rich repeat-containing protein 41 isoform X1 K10347 LRRC41; leucine-rich repeat-containing protein 41
E 121045342 RSPRY1; RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
E 121024609 ANKRD9; ankyrin repeat domain-containing protein 9 K25208 ANKRD9; ankyrin repeat domain-containing protein 9
E 121031727 KLHDC1; kelch domain-containing protein 1 K25810 KLHDC1; kelch domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 121029470 CUL7; cullin-7 isoform X1 K10613 CUL7; cullin 7
D Adaptor protein
E 121010703 SKP1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
E 121010276 FBXW8; F-box/WD repeat-containing protein 8 isoform X1 K10264 FBXW8; F-box and WD-40 domain protein 8
C Cul8 complex
D Ring finger protein
E 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 121040293 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 121029479 CUL9; cullin-9 isoform X1 K11970 CUL9; cullin 9
C APC/C
D Ring finger protein
E 121018073 ANAPC11; anaphase-promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 121020237 ANAPC2; anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 121026987 CDC20; cell division cycle protein 20 homolog isoform X1 K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 121024233 FZR1; fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 121044441 ANAPC1; anaphase-promoting complex subunit 1 isoform X1 K03348 APC1; anaphase-promoting complex subunit 1
E 121020149 CDC27; cell division cycle protein 27 homolog isoform X1 K03350 APC3; anaphase-promoting complex subunit 3
E 121037338 ANAPC4; anaphase-promoting complex subunit 4 isoform X1 K03351 APC4; anaphase-promoting complex subunit 4
E 121010453 ANAPC5; anaphase-promoting complex subunit 5 isoform X1 K03352 APC5; anaphase-promoting complex subunit 5
E 121037660 CDC16; cell division cycle protein 16 homolog isoform X1 K03353 APC6; anaphase-promoting complex subunit 6
E 121010456 ANAPC7; anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 121010758 CDC23; cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 121029057 ANAPC10; anaphase-promoting complex subunit 10 isoform X1 K03357 APC10; anaphase-promoting complex subunit 10
E 121034857 CDC26; anaphase-promoting complex subunit CDC26 isoform X1 K03359 APC12; anaphase-promoting complex subunit 12
E 121022444 LOW QUALITY PROTEIN: anaphase-promoting complex subunit 13-like K12456 APC13; anaphase-promoting complex subunit 13
E 121033704 ANAPC13; anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 121039226 ANAPC15; anaphase-promoting complex subunit 15 isoform X1 K25228 APC15; anaphase-promoting complex subunit 15
E 121036766 ANAPC16; anaphase-promoting complex subunit 16 K25229 APC16; anaphase-promoting complex subunit 16
C BRCC complex
D 121045059 BRCA1; breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 121012828 BRCA2; breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
D 121024836 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 121031025 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
D 121044280 BABAM2; BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
D 121041518 RAD51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 121011203 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 121022872 UBAC1; ubiquitin-associated domain-containing protein 1 isoform X1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 121043132 SHARPIN; sharpin isoform X1 K20894 SHARPIN; shank-associated RH domain-interacting protein
D 121012362 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 121031551 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 121026831 E3 ubiquitin-protein transferase RMND5B isoform X1 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 121026834 E3 ubiquitin-protein transferase RMND5B isoform X1 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 121044492 RMND5A; E3 ubiquitin-protein transferase RMND5A isoform X1 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 121020419 RANBP9; ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 121045469 RANBP10; ran-binding protein 10 isoform X1 K23334 RANBP9_10; Ran-binding protein 9/10
D 121033724 ARMC8; armadillo repeat-containing protein 8 isoform X1 K23336 ARMC8; armadillo repeat-containing protein 8
D 121028321 MKLN1; muskelin isoform X1 K23337 MKLN1; muskelin
D 121039580 MAEA; E3 ubiquitin-protein transferase MAEA isoform X1 K18624 MAEA; macrophage erythroblast attacher
D 121015810 GID4; glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 121020024 GID8; glucose-induced degradation protein 8 homolog isoform X1 K23338 GID8; glucose-induced degradation protein 8
D 121044302 YPEL5; protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 121015180 WDR26; WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 121045328 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 121024280 TMUB1; transmembrane and ubiquitin-like domain-containing protein 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 121045089 TMUB2; transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 121020183 ERLIN2; erlin-2 K23341 ERLIN; erlin
D 121037104 ERLIN1; erlin-1 isoform X1 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 121038620 LMBR1L; protein LMBR1L K25215 LMBR1L; protein LMBR1L
D 121045328 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 121037765 UBAC2; ubiquitin-associated domain-containing protein 2 isoform X1 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C STUB1-CHIC2 complex
D 121019768 STUB1; E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
D 121035747 CHIC2; cysteine-rich hydrophobic domain-containing protein 2 isoform X1 K28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 121040789 CAND1; cullin-associated NEDD8-dissociated protein 1 isoform X1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 121041236 CAND2; cullin-associated NEDD8-dissociated protein 2 isoform X1 K24172 CAND2; cullin-associated NEDD8-dissociated protein 2
D 121022300 COMMD1; COMM domain-containing protein 1 isoform X1 K22557 COMMD1; COMM domain containing 1
D 121033827 COMMD2; COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 121024516 COMMD3; COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 121042010 COMMD4; COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 121043165 COMMD5; COMM domain-containing protein 5 K22561 COMMD5; COMM domain containing 5
D 121037849 COMMD6; COMM domain-containing protein 6 K22562 COMMD6; COMM domain containing 6
D 121012319 COMMD7; COMM domain-containing protein 7 isoform X1 K22563 COMMD7; COMM domain containing 7
D 121036218 COMMD8; COMM domain-containing protein 8 isoform X1 K22564 COMMD8; COMM domain containing 8
D 121043539 COMMD9; COMM domain-containing protein 9 K22565 COMMD9; COMM domain containing 9
D 121010560 COMMD10; COMM domain-containing protein 10 isoform X1 K22566 COMMD10; COMM domain containing 10
D 121026062 CCDC22; coiled-coil domain-containing protein 22 K23343 CCDC22; coiled-coil domain-containing protein 22
D 121012431 DDRGK1; DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 121027477 GLMN; glomulin isoform X1 K23345 GLMN; glomulin
D 121011847 influenza virus NS1A-binding protein K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 121036387 UBXN7; UBX domain-containing protein 7 isoform X1 K24350 UBXN7; UBX domain-containing protein 7
D 121013070 PACRG; parkin coregulated gene protein K26163 PACRG; parkin coregulated gene protein
D 121015669 UBAP2L; ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 121034579 UBAP2; ubiquitin-associated protein 2 isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 121043682 UEVLD; ubiquitin-conjugating enzyme E2 variant 3 isoform X1 K28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 121036500 UCHL1; ubiquitin carboxyl-terminal hydrolase isozyme L1 K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
D 121016878 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 121037846 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 121016165 UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 121045278 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD isoform X1 K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 121027234 USP1; ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 121035515 USP2; ubiquitin carboxyl-terminal hydrolase 2 isoform X1 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 121041810 USP3; ubiquitin carboxyl-terminal hydrolase 3 isoform X1 K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 121011191 USP4; ubiquitin carboxyl-terminal hydrolase 4 isoform X1 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 121026176 USP11; ubiquitin carboxyl-terminal hydrolase 11 isoform X1 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 121021962 USP5; ubiquitin carboxyl-terminal hydrolase 5 isoform X1 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 121034028 USP13; ubiquitin carboxyl-terminal hydrolase 13 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 121044669 USP32; ubiquitin carboxyl-terminal hydrolase 32 isoform X1 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 121019544 USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 121041689 USP8; ubiquitin carboxyl-terminal hydrolase 8 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 121024772 probable ubiquitin carboxyl-terminal hydrolase FAF-X K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 121026028 USP9X; probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 121027186 USP24; ubiquitin carboxyl-terminal hydrolase 24 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 121009873 ubiquitin carboxyl-terminal hydrolase 10 isoform X1 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 121012764 USP12; ubiquitin carboxyl-terminal hydrolase 12 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 121035872 USP46; ubiquitin carboxyl-terminal hydrolase 46 isoform X1 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 121033121 USP14; ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 121040838 USP15; ubiquitin carboxyl-terminal hydrolase 15 isoform X1 K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D 121029818 USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 121036035 USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 121021290 ubiquitin carboxyl-terminal hydrolase 17-like protein 6 K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
D 121021947 USP18; ubl carboxyl-terminal hydrolase 18 K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
D 121011181 USP19; ubiquitin carboxyl-terminal hydrolase 19 isoform X1 K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 121027344 USP33; ubiquitin carboxyl-terminal hydrolase 33 isoform X1 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 121035104 USP20; ubiquitin carboxyl-terminal hydrolase 20 isoform X1 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 121015483 USP21; ubiquitin carboxyl-terminal hydrolase 21 isoform X1 K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
D 121015788 USP22; ubiquitin carboxyl-terminal hydrolase 22 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 121025895 USP51; ubiquitin carboxyl-terminal hydrolase 51 isoform X1 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 121026018 USP27X; ubiquitin carboxyl-terminal hydrolase 27 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 121036074 USP25; ubiquitin carboxyl-terminal hydrolase 25 isoform X1 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 121025563 USP26; ubiquitin carboxyl-terminal hydrolase 26 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 121031067 USP37; ubiquitin carboxyl-terminal hydrolase 37 isoform X1 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 121035405 USP28; ubiquitin carboxyl-terminal hydrolase 28 isoform X1 K21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
D 121010189 USP30; ubiquitin carboxyl-terminal hydrolase 30 isoform X1 K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 121019810 USP31; ubiquitin carboxyl-terminal hydrolase 31 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 121016242 USP34; ubiquitin carboxyl-terminal hydrolase 34 isoform X1 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 121029211 USP38; ubiquitin carboxyl-terminal hydrolase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 121039344 USP35; ubiquitin carboxyl-terminal hydrolase 35 isoform X1 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 121017561 USP42; ubiquitin carboxyl-terminal hydrolase 42 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 121017997 USP36; ubiquitin carboxyl-terminal hydrolase 36 isoform X1 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 121014401 USP40; ubiquitin carboxyl-terminal hydrolase 40 isoform X1 K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
D 121015914 USP43; ubiquitin carboxyl-terminal hydrolase 43 K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]
D 121029243 USP49; ubiquitin carboxyl-terminal hydrolase 49 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 121040587 USP44; ubiquitin carboxyl-terminal hydrolase 44 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 121018208 USP47; ubiquitin carboxyl-terminal hydrolase 47 isoform X1 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 121022760 USP48; ubiquitin carboxyl-terminal hydrolase 48 isoform X1 K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
D 121036790 USP54; inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X1 K27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]
C OTU
D 121023630 OTUB1; ubiquitin thioesterase OTUB1 K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 121032234 OTUB2; ubiquitin thioesterase OTUB2 K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]
D 121022247 OTUD3; OTU domain-containing protein 3 isoform X1 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 121025942 OTUD5; OTU domain-containing protein 5 isoform X1 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 121025285 OTUD6A; OTU domain-containing protein 6A K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 121042684 OTUD6B; deubiquitinase OTUD6B isoform X1 K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 121020986 OTUD7B; OTU domain-containing protein 7B K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 121042562 OTUD7A; OTU domain-containing protein 7A K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 121042817 OTULIN; ubiquitin thioesterase otulin isoform X1 K18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]
D 121013398 TNFAIP3; tumor necrosis factor alpha-induced protein 3 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 121038167 VCPIP1; deubiquitinating protein VCPIP1 K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 121037360 ZRANB1; ubiquitin thioesterase ZRANB1 isoform X1 K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 121032208 ATXN3; ataxin-3 isoform X1 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 121019000 JOSD2; josephin-2 isoform X1 K15235 JOSD; josephin [EC:3.4.19.12]
D 121040338 JOSD1; josephin-1 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 121021070 MINDY1; ubiquitin carboxyl-terminal hydrolase MINDY-1 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 121041773 MINDY2; ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform X1 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 121014770 MINDY3; ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 121028522 MINDY4; probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 121034194 MINDY4B; inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 121024836 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 121027213 MYSM1; deubiquitinase MYSM1 isoform X1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 121021408 MPND; LOW QUALITY PROTEIN: MPN domain-containing protein K24173 MPND; MPN domain-containing protein
D 121030609 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 121019248 STAM-binding protein isoform X1 K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D 121016584 STAMBPL1; AMSH-like protease K11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]
C PPPDE
D 121015122 DESI2; deubiquitinase DESI2 isoform X1 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 121029956 ZUP1; zinc finger-containing ubiquitin peptidase 1 isoform X1 K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 121037485 ABRAXAS2; BRISC complex subunit Abraxas 2 K20799 FAM175B; BRISC complex subunit Abro1
D 121010969 BABAM1; BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
D 121024836 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 121044280 BABAM2; BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 121038655 SENP1; sentrin-specific protease 1 isoform X1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 121034106 SENP2; sentrin-specific protease 2 isoform X1 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C 121015988 SENP3; sentrin-specific protease 3 K08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
C 121036398 SENP5; sentrin-specific protease 5 isoform X1 K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C 121029681 SENP6; sentrin-specific protease 6 isoform X1 K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C 121036169 SENP7; sentrin-specific protease 7 isoform X1 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 121041944 SENP8; sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 121037846 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 121040264 DESI1; desumoylating isopeptidase 1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 121012806 USPL1; SUMO-specific isopeptidase USPL1 isoform X1 K23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
C COP9 signalosome (CSN) complex
D 121025309 GPS1; COP9 signalosome complex subunit 1 isoform X1 K12175 GPS1; COP9 signalosome complex subunit 1
D 121041676 COPS2; COP9 signalosome complex subunit 2 isoform X1 K12176 COPS2; COP9 signalosome complex subunit 2
D 121015796 COPS3; COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 121033356 COPS4; COP9 signalosome complex subunit 4 isoform X1 K12178 COPS4; COP9 signalosome complex subunit 4
D 121038158 COPS5; COP9 signalosome complex subunit 5 isoform X1 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 121017601 COPS6; COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 121039836 LOW QUALITY PROTEIN: COP9 signalosome complex subunit 6-like K12179 COPS6; COP9 signalosome complex subunit 6
D 121014434 COPS7B; COP9 signalosome complex subunit 7b isoform X1 K12180 COPS7; COP9 signalosome complex subunit 7
D 121022130 COPS7A; COP9 signalosome complex subunit 7a isoform X1 K12180 COPS7; COP9 signalosome complex subunit 7
D 121014379 COPS8; COP9 signalosome complex subunit 8 isoform X1 K12181 COPS8; COP9 signalosome complex subunit 8
D 121014342 COPS9; COP9 signalosome complex subunit 9 K28062 COPS9; COP9 signalosome complex subunit 9
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 28, 2025