+F Repair protein KO #

  DNA Repair and Recombination Proteins - Rhinopithecus bieti (black snub-nosed monkey)

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AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D 108519589 MGMT; methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D 108534388 ALKBH2; DNA oxidative demethylase ALKBH2 isoform X1 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33] D 108519277 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1 K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54] D 108540672 ASCC3; activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] D 108520834 activating signal cointegrator 1 complex subunit 3-like K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] C BER (base exicision repair) D DNA glycosylases E 108534404 UNG; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E 108530982 CCNO; cyclin-O K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-] E 108544252 TDG; LOW QUALITY PROTEIN: G/T mismatch-specific thymine DNA glycosylase K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] E 108521112 MPG; DNA-3-methyladenine glycosylase isoform X1 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E 108514631 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] E 108535656 MUTYH; adenine DNA glycosylase isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E 108537514 MBD4; methyl-CpG-binding domain protein 4 isoform X1 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] E 108534807 OGG1; N-glycosylase/DNA lyase isoform X1 K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] E 108517000 NEIL1; endonuclease 8-like 1 isoform X1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] E 108536703 NEIL2; endonuclease 8-like 2 isoform X1 K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18] E 108534050 NEIL3; endonuclease 8-like 3 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18] E 108519400 NTHL1; endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E 108527309 APEX1; DNA-(apurinic or apyrimidinic site) lyase K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] E 108540601 APEX2; DNA-(apurinic or apyrimidinic site) lyase 2 isoform X1 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2] D Long Patch-BER factors E DNA polymerase delta complex F 108535799 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] F 108544013 POLD2; DNA polymerase delta subunit 2 isoform X1 K02328 POLD2; DNA polymerase delta subunit 2 F 108537642 POLD3; DNA polymerase delta subunit 3 isoform X1 K03504 POLD3; DNA polymerase delta subunit 3 E DNA polymerase epsilon complex F 108544513 POLE; LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] F 108513660 POLE2; DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] F 108532151 POLE3; DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] F 108531691 POLE4; DNA polymerase epsilon subunit 4 isoform X1 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] E 108533343 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen E 108533602 FEN1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] E 108540136 LIG1; DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Short Patch-BER factors E 108540714 POLB; DNA polymerase beta isoform X1 K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] E 108538045 XRCC1; DNA repair protein XRCC1 isoform X1 K10803 XRCC1; DNA-repair protein XRCC1 E 108541384 LIG3; DNA ligase 3 isoform X1 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1] D Other BER factors E 108535901 TDP1; LOW QUALITY PROTEIN: tyrosyl-DNA phosphodiesterase 1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] E 108518241 APTX; aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] E 108516361 APLF; LOW QUALITY PROTEIN: aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] E 108535816 PNKP; bifunctional polynucleotide phosphatase/kinase isoform X1 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] E 108524822 HMGB1; LOW QUALITY PROTEIN: high mobility group protein B1 K10802 HMGB1; high mobility group protein B1 E 108515127 POLL; DNA polymerase lambda isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] E 108535931 PARP1; poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] E 108515410 PARP4; poly [ADP-ribose] polymerase 4 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] E 108519663 PARP3; poly [ADP-ribose] polymerase 3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] E 108527305 PARP2; poly [ADP-ribose] polymerase 2 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex F 108544868 XPC; DNA repair protein complementing XP-C cells isoform X1 K10838 XPC; xeroderma pigmentosum group C-complementing protein F 108532559 RAD23B; UV excision repair protein RAD23 homolog B isoform X1 K10839 RAD23; UV excision repair protein RAD23 F 108544095 RAD23A; UV excision repair protein RAD23 homolog A isoform X1 K10839 RAD23; UV excision repair protein RAD23 F 108513869 CETN2; centrin-2 isoform X1 K10840 CETN2; centrin-2 E Cul4-DDB2 complex F 108528465 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F 108521807 CUL4A; cullin-4A K10609 CUL4; cullin 4 F 108522824 LOW QUALITY PROTEIN: cullin-4B-like K10609 CUL4; cullin 4 F 108534998 CUL4B; LOW QUALITY PROTEIN: cullin-4B K10609 CUL4; cullin 4 F 108533616 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1 F 108521962 DDB2; DNA damage-binding protein 2 K10140 DDB2; DNA damage-binding protein 2 E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex F 108514411 POLR2A; DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] F 108513476 POLR2B; LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] F 108533880 POLR2C; DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 F 108533011 uncharacterized protein LOC108533011 isoform X1 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 F 108537888 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 F 108521456 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 F 108533567 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 F 108525206 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 F 108513047 POLR2I; DNA-directed RNA polymerase II subunit RPB9 isoform X1 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 F 108513014 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 F 108542211 LOW QUALITY PROTEIN: DNA-directed RNA polymerases I, II, and III subunit RPABC5-like K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 F 108518910 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a isoform X1 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 F 108520201 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 E Cul4-CSA complex F 108528465 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F 108521807 CUL4A; cullin-4A K10609 CUL4; cullin 4 F 108522824 LOW QUALITY PROTEIN: cullin-4B-like K10609 CUL4; cullin 4 F 108534998 CUL4B; LOW QUALITY PROTEIN: cullin-4B K10609 CUL4; cullin 4 F 108533616 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1 F 108515485 ERCC8; DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8 E Other TCR factor F 108537804 ERCC6; LOW QUALITY PROTEIN: DNA excision repair protein ERCC-6 K10841 ERCC6; DNA excision repair protein ERCC-6 F 108524370 UVSSA; UV-stimulated scaffold protein A isoform X1 K23720 UVSSA; UV-stimulated scaffold protein A F 108527908 ELOF1; transcription elongation factor 1 homolog isoform X1 K25829 ELOF1; transcription elongation factor 1 D TFIIH complex E 108532999 ERCC3; TFIIH basal transcription factor complex helicase XPB subunit isoform X1 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] E 108531103 ERCC2; TFIIH basal transcription factor complex helicase XPD subunit K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] E 108519180 GTF2H1; general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 E 108541125 GTF2H2; general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 E 108540659 GTF2H3; general transcription factor IIH subunit 3 isoform X1 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 E 108522581 GTF2H4; general transcription factor IIH subunit 4 isoform X1 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 E 108540553 GTF2H5; general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit E 108541177 CDK7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] E 108541124 CCNH; cyclin-H isoform X1 K06634 CCNH; cyclin H E 108520157 MNAT1; CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1 D RPA (replication factor A) E 108526229 RPA1; replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1 E 108518201 RPA2; LOW QUALITY PROTEIN: replication protein A 32 kDa subunit K10739 RFA2; replication factor A2 E 108543412 RPA3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3 E 108534789 RPA4; replication protein A 30 kDa subunit K10741 RPA4; replication factor A4 D Other NER factors E 108539109 XPA; DNA repair protein complementing XP-A cells isoform X1 K10847 XPA; DNA-repair protein complementing XP-A cells E 108531042 ERCC1; DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1 E 108541251 ERCC4; LOW QUALITY PROTEIN: DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] E 108521487 DNA repair protein complementing XP-G cells isoform X1 K10846 ERCC5; DNA excision repair protein ERCC-5 E 108540136 LIG1; DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] E 108534639 MMS19; MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19 E 108514199 CUL3; LOW QUALITY PROTEIN: cullin-3 K03869 CUL3; cullin 3 E 108517384 CUL5; cullin-5 K10612 CUL5; cullin 5 E 108515043 TCEB1; transcription elongation factor B polypeptide 1 isoform X1 K03872 ELOC; elongin-C E 108534614 transcription elongation factor B polypeptide 1-like K03872 ELOC; elongin-C E 108523321 TCEB2; transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B E 108531561 transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B E 108538413 TCEB3; transcription elongation factor B polypeptide 3 K15076 ELOA; elongin-A E 108519032 TCEB3B; RNA polymerase II transcription factor SIII subunit A2 K15076 ELOA; elongin-A E 108519035 LOW QUALITY PROTEIN: RNA polymerase II transcription factor SIII subunit A3-like-1 K15076 ELOA; elongin-A E 108526632 UBAP2L; ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2 E 108542189 ubiquitin-associated protein 2 K26545 UBAP2; ubiquitin-associated protein 2 C MMR (mismatch excision repair) D Mismatch and loop recognition factors E 108512671 MSH2; DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2 E 108528914 MSH3; DNA mismatch repair protein Msh3 isoform X1 K08736 MSH3; DNA mismatch repair protein MSH3 E 108527513 MSH6; DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6 D MutL homologs E 108524462 PMS1; PMS1 protein homolog 1 K10864 PMS1; DNA mismatch repair protein PMS1 E 108525674 MLH1; LOW QUALITY PROTEIN: DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1 E 108523985 PMS2; mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2 E 108534923 MLH3; LOW QUALITY PROTEIN: DNA mismatch repair protein Mlh3 K08739 MLH3; DNA mismatch repair protein MLH3 D DNA polymerase delta complex E 108535799 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] E 108544013 POLD2; DNA polymerase delta subunit 2 isoform X1 K02328 POLD2; DNA polymerase delta subunit 2 E 108537642 POLD3; DNA polymerase delta subunit 3 isoform X1 K03504 POLD3; DNA polymerase delta subunit 3 D RPA (replication factor A) E 108526229 RPA1; replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1 E 108518201 RPA2; LOW QUALITY PROTEIN: replication protein A 32 kDa subunit K10739 RFA2; replication factor A2 E 108543412 RPA3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3 E 108534789 RPA4; replication protein A 30 kDa subunit K10741 RPA4; replication factor A4 D RFC (replication factor C) E 108536748 RFC1; LOW QUALITY PROTEIN: replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1 E 108526526 RFC2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4 E 108530459 RFC4; replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4 E 108539296 RFC5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5 E 108522735 RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5 D Other MMR factors E 108533343 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen E 108512530 EXO1; LOW QUALITY PROTEIN: exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-] E 108524822 HMGB1; LOW QUALITY PROTEIN: high mobility group protein B1 K10802 HMGB1; high mobility group protein B1 E 108540136 LIG1; DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] E 108521300 WDR76; LOW QUALITY PROTEIN: WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76 B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex E 108535749 MRE11A; LOW QUALITY PROTEIN: double-strand break repair protein MRE11A K10865 MRE11; double-strand break repair protein MRE11 E 108529586 RAD50; LOW QUALITY PROTEIN: DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] E 108526906 NBN; nibrin K10867 NBN; nibrin D BRCA1-core complex E 108526765 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 108517972 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1 D BRCA1-A complex E 108526765 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 108531151 FAM175A; BRCA1-A complex subunit Abraxas isoform X1 K20774 FAM175A; BRCA1-A complex subunit Abraxas E 108544790 UIMC1; BRCA1-A complex subunit RAP80 isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80 E 108534248 BABAM1; BRISC and BRCA1-A complex member 1 isoform X1 K20776 BABAM; BRISC and BRCA1-A complex member 1 E 108532734 BRE; BRCA1-A complex subunit BRE isoform X1 K12173 BRE; BRCA1-A complex subunit BRE E 108538182 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] E 108517087 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] D BRCA1-B complex E 108526765 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 108528833 BRIP1; LOW QUALITY PROTEIN: Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] E 108529872 TOPBP1; DNA topoisomerase 2-binding protein 1 isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 D BRCA1-C complex E 108526765 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 108536918 RBBP8; LOW QUALITY PROTEIN: DNA endonuclease RBBP8 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-] E 108535749 MRE11A; LOW QUALITY PROTEIN: double-strand break repair protein MRE11A K10865 MRE11; double-strand break repair protein MRE11 E 108529586 RAD50; LOW QUALITY PROTEIN: DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] E 108526906 NBN; nibrin K10867 NBN; nibrin D BRCA complex E 108526765 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 108524798 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein E 108517532 breast cancer type 2 susceptibility protein-like K08775 BRCA2; breast cancer 2 susceptibility protein E 108538852 PALB2; LOW QUALITY PROTEIN: partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2 E 108523406 RAD51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51 D RecA family proteins E 108523406 RAD51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51 E 108533725 RAD51B; DNA repair protein RAD51 homolog 2 isoform X1 K10869 RAD51L1; RAD51-like protein 1 E 108521632 RAD51C; LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2 E 108541380 RAD51D; DNA repair protein RAD51 homolog 4 isoform X1 K10871 RAD51L3; RAD51-like protein 3 E 108520764 XRCC2; DNA repair protein XRCC2 K10879 XRCC2; DNA-repair protein XRCC2 E 108521878 XRCC3; DNA repair protein XRCC3 K10880 XRCC3; DNA-repair protein XRCC3 D Rad52 family proteins E 108519490 RAD52; DNA repair protein RAD52 homolog isoform X1 K10873 RAD52; DNA repair and recombination protein RAD52 E 108541462 RDM1; RAD52 motif-containing protein 1 isoform X1 K10874 RDM1; RAD52 motif-containing protein 1 D Rad54 family proteins E 108535630 RAD54L; DNA repair and recombination protein RAD54-like isoform X1 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] E 108540115 RAD54L2; helicase ARIP4 isoform X1 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] E 108521904 RAD54B; DNA repair and recombination protein RAD54B K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] D RecQ family DNA helicases E 108539728 RECQL; ATP-dependent DNA helicase Q1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] E 108518678 WRN; Werner syndrome ATP-dependent helicase isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4] E 108517228 BLM; LOW QUALITY PROTEIN: Bloom syndrome protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4] E 108536615 RECQL4; LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4] E 108537353 RECQL5; ATP-dependent DNA helicase Q5 isoform X1 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4] D Bloom's syndrome complex (BTR) E 108517228 BLM; LOW QUALITY PROTEIN: Bloom syndrome protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4] E 108516623 TOP3A; DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 108536067 TOP3B; DNA topoisomerase 3-beta-1 isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 108529855 RMI1; recQ-mediated genome instability protein 1 isoform X1 K10990 RMI1; RecQ-mediated genome instability protein 1 E 108541234 RMI2; recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2 D RPA (replication factor A) E 108526229 RPA1; replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1 E 108518201 RPA2; LOW QUALITY PROTEIN: replication protein A 32 kDa subunit K10739 RFA2; replication factor A2 E 108543412 RPA3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3 E 108534789 RPA4; replication protein A 30 kDa subunit K10741 RPA4; replication factor A4 D Protein phosphatase 4 E 108515700 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 catalytic subunit-like K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] E 108537904 serine/threonine-protein phosphatase 4 catalytic subunit-like K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] E 108513260 serine/threonine-protein phosphatase 4 catalytic subunit-like K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] E 108515310 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 E 108523919 PPP4R1; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 E 108541443 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 2-like K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 E 108542236 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 E 108520478 PPP4R3B; serine/threonine-protein phosphatase 4 regulatory subunit 3B K17491 SMEK; protein phosphatase 4 regulatory subunit 3 E 108519144 PPP4R3A; serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3 E 108513265 LOW QUALITY PROTEIN: putative SMEK homolog 3 K17491 SMEK; protein phosphatase 4 regulatory subunit 3 E 108519063 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 D AP-5 complex E 108518712 AP5B1; AP-5 complex subunit beta-1 K19022 AP5B1; AP-5 complex subunit beta-1 E 108529733 AP5M1; AP-5 complex subunit mu-1 K19023 AP5M1; AP-5 complex subunit mu-1 E 108533508 AP5S1; AP-5 complex subunit sigma-1 isoform X1 K19024 AP5S1; AP-5 complex subunit sigma-1 E 108543960 AP5Z1; AP-5 complex subunit zeta-1 isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1 D SMC5-SMC6 complex E 108530280 SMC5; LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5 E 108529246 SMC6; LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6 E 108529235 FAM84A; protein FAM84A K22805 FAM84A; protein FAM84A E 108538863 NSMCE1; non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] E 108538083 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] E 108526797 NSMCE3; non-structural maintenance of chromosomes element 3 homolog K22823 NSMCE3; non-structural maintenance of chromosomes element 3 E 108529764 NSMCE4A; non-structural maintenance of chromosomes element 4 homolog A isoform X1 K22825 NSMCE4; non-structural maintenance of chromosomes element 4 E 108544266 EID3; EP300-interacting inhibitor of differentiation 3 K22826 EID3; EP300-interacting inhibitor of differentiation 3 E 108534653 SLF1; LOW QUALITY PROTEIN: SMC5-SMC6 complex localization factor protein 1 K26126 SLF1; SMC5-SMC6 complex localization factor protein 1 E 108515122 SLF2; LOW QUALITY PROTEIN: SMC5-SMC6 complex localization factor protein 2 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2 D Other HR factors E 108516429 EME1; crossover junction endonuclease EME1 isoform X1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] E 108519383 EME2; probable crossover junction endonuclease EME2 isoform X1 K10883 EME2; crossover junction endonuclease EME2 E 108533736 EXD2; exonuclease 3'-5' domain-containing protein 2 isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] E 108518635 MUS81; crossover junction endonuclease MUS81 isoform X1 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] E 108513536 SHFM1; 26S proteasome complex subunit DSS1 isoform X1 K10881 SHFM1; 26 proteasome complex subunit DSS1 E 108521850 DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3 E 108512783 SWI5; LOW QUALITY PROTEIN: DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3 E 108515072 SFR1; swi5-dependent recombination DNA repair protein 1 homolog isoform X1 K10992 SFR1; Swi5-dependent recombination DNA repair protein 1 E 108523681 SLX1A; structure-specific endonuclease subunit SLX1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] E 108538274 SLX4; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) E 108529245 GEN1; flap endonuclease GEN homolog 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] E 108521290 SPG11; spatacsin K19026 SPG11; spatacsin E 108533723 ZFYVE26; LOW QUALITY PROTEIN: zinc finger FYVE domain-containing protein 26 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26 E 108536504 RAD51AP1; LOW QUALITY PROTEIN: RAD51-associated protein 1 K20778 RAD51AP1; RAD51-associated protein 1 E 108538644 MORF4L1; mortality factor 4-like protein 1 isoform X1 K11339 MORF4L1; mortality factor 4-like protein 1 E 108519837 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 108527365 FIGNL1; LOW QUALITY PROTEIN: fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] E 108520139 DNA repair-scaffolding protein-like K22806 SPIDR; DNA repair-scaffolding protein E 108523060 SPIDR; DNA repair-scaffolding protein isoform X1 K22806 SPIDR; DNA repair-scaffolding protein E 108523031 FAM84B; protein FAM84B K22810 FAM84B; protein FAM84B E 108543804 BRAT1; BRCA1-associated ATM activator 1 isoform X1 K23112 BRAT1; BRCA1-associated ATM activator 1 E 108539808 CUNH21orf2; protein C21orf2 isoform X1 K23456 CFAP410; cilla- and flagella-associated protein E 108512082 hepatoma-derived growth factor-related protein 2 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2 E 108522164 ZSWIM7; zinc finger SWIM domain-containing protein 7 isoform X1 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7 E 108527918 SWSAP1; ATPase SWSAP1 K25771 SWSAP1; ATPase SWSAP1 E 108527399 EMSY; BRCA2-interacting transcriptional repressor EMSY isoform X1 K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY E 108539775 HSF2BP; heat shock factor 2-binding protein K25791 HSF2BP; heat shock factor 2-binding protein E 108538593 MMS22L; protein MMS22-like isoform X1 K26125 MMS22L; protein MMS22-like E 108536604 TONSL; LOW QUALITY PROTEIN: tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 E 108542685 BOD1L1; LOW QUALITY PROTEIN: biorientation of chromosomes in cell division protein 1-like 1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 E 108543131 PARPBP; PCNA-interacting partner isoform X1 K27412 PARPBP; PCNA-interacting partner C NHEJ (non-homologous end-joining) D DNA-PK complex E 108528479 XRCC6; LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 6 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 E 108544377 XRCC5; X-ray repair cross-complementing protein 5 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 E 108535350 PRKDC; DNA-dependent protein kinase catalytic subunit isoform X1 K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1] D MRX complex E 108535749 MRE11A; LOW QUALITY PROTEIN: double-strand break repair protein MRE11A K10865 MRE11; double-strand break repair protein MRE11 E 108529586 RAD50; LOW QUALITY PROTEIN: DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] D DNA Ligase 4 complex E 108527049 LIG4; LOW QUALITY PROTEIN: DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] E 108514220 XRCC4; DNA repair protein XRCC4 K10886 XRCC4; DNA-repair protein XRCC4 E 108518428 NHEJ1; non-homologous end-joining factor 1 isoform X1 K10980 NHEJ1; non-homologous end-joining factor 1 D X-family DNA polymerases E 108515127 POLL; DNA polymerase lambda isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] E 108544007 POLM; DNA-directed DNA/RNA polymerase mu isoform X1 K03513 POLM; DNA polymerase mu [EC:2.7.7.7] E 108534467 DNTT; DNA nucleotidylexotransferase isoform X1 K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31] E 108540714 POLB; DNA polymerase beta isoform X1 K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] D Other NHEJ factors E 108518241 APTX; aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] E 108516361 APLF; LOW QUALITY PROTEIN: aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] E 108531018 DCLRE1C; protein artemis isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-] E 108533662 TDP2; tyrosyl-DNA phosphodiesterase 2 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] E 108516707 SMCHD1; LOW QUALITY PROTEIN: structural maintenance of chromosomes flexible hinge domain-containing protein 1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 E 108530251 PWWP domain-containing protein MUM1 isoform X1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3 E 108540268 MUM1L1; PWWP domain-containing protein MUM1L1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3 E 108542910 CUNH9orf142; protein PAXX isoform X1 K25772 PAXX; protein PAXX E 108539204 CUNH7orf49; modulator of retrovirus infection homolog isoform X1 K26155 CYREN; cell cycle regulator of non-homologous end joining E 108519430 jmjC domain-containing protein 8 isoform X1 K25792 JMJD8; jumonji domain-containing protein 8 E 108519432 JMJD8; LOW QUALITY PROTEIN: jmjC domain-containing protein 8 K25792 JMJD8; jumonji domain-containing protein 8 E 108533267 CUNH20orf196; uncharacterized protein C20orf196 homolog isoform X1 K26128 SHLD1; shieldin complex subunit 1 E 108533121 FAM35A; protein FAM35A isoform X1 K26129 SHLD2; shieldin complex subunit 2 C FA (Fanconi anemia) pathway D FA core complex E 108528984 FANCA; Fanconi anemia group A protein K10888 FANCA; fanconi anemia group A protein E 108522938 Fanconi anemia group B protein K10889 FANCB; fanconi anemia group B protein E 108517450 LOW QUALITY PROTEIN: Fanconi anemia group B protein-like K10889 FANCB; fanconi anemia group B protein E 108529290 FANCC; Fanconi anemia group C protein isoform X1 K10890 FANCC; fanconi anemia group C protein E 108528314 FANCE; Fanconi anemia group E protein isoform X1 K10892 FANCE; fanconi anemia group E protein E 108541794 FANCF; Fanconi anemia group F protein K10893 FANCF; fanconi anemia group F protein E 108524471 FANCG; Fanconi anemia group G protein isoform X1 K10894 FANCG; fanconi anemia group G protein E 108513343 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] E 108537060 FANCM; LOW QUALITY PROTEIN: Fanconi anemia group M protein K10896 FANCM; fanconi anemia group M protein E 108517257 FAAP24; Fanconi anemia core complex-associated protein 24 isoform X1 K10898 FAAP24; fanconi anemia-associated protein E 108534122 FAAP100; Fanconi anemia core complex-associated protein 100 isoform X1 K10993 FAAP100; fanconi anemia core complex 100 kDa subunit D FA core complex binding factors E 108530502 HES1; LOW QUALITY PROTEIN: transcription factor HES-1 K06054 HES1; hairy and enhancer of split 1 E 108539344 centromere protein S isoform X1 K11511 APITD1; centromere protein S E 108534097 STRA13; centromere protein X isoform X1 K15360 STRA13; centromere protein X E 108545063 UBE2T; ubiquitin-conjugating enzyme E2 T isoform X1 K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] D Bloom's syndrome complex (BTR) E 108517228 BLM; LOW QUALITY PROTEIN: Bloom syndrome protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4] E 108516623 TOP3A; DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 108536067 TOP3B; DNA topoisomerase 3-beta-1 isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 108529855 RMI1; recQ-mediated genome instability protein 1 isoform X1 K10990 RMI1; RecQ-mediated genome instability protein 1 E 108541234 RMI2; recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2 D FANCD2-I complex E 108512269 FANCD2; LOW QUALITY PROTEIN: Fanconi anemia group D2 protein K10891 FANCD2; fanconi anemia group D2 protein E 108540890 FANCI; LOW QUALITY PROTEIN: Fanconi anemia group I protein K10895 FANCI; fanconi anemia group I protein D Downstream FA components E 108526765 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 108524798 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein E 108517532 breast cancer type 2 susceptibility protein-like K08775 BRCA2; breast cancer 2 susceptibility protein E 108528833 BRIP1; LOW QUALITY PROTEIN: Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] E 108538852 PALB2; LOW QUALITY PROTEIN: partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2 D Other FA pathway factors E 108531781 FAN1; fanconi-associated nuclease 1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] E 108523406 RAD51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51 E 108521632 RAD51C; LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2 E 108519381 TELO2; LOW QUALITY PROTEIN: telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein E 108532907 USP1; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] E 108513779 WDR48; WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48 C Other DSBR factors D Protein phosphatase 6 E 108531355 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] E 108542500 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1 K15499 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1 E 108539412 PPP6R2; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 6 regulatory subunit 2 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 E 108538514 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 E 108535136 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A E 108527827 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B E 108516014 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X1 K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C D Ubiquitin ligases E 108528350 RNF8; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF8 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] E 108542275 RNF168; E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31] E 108537629 RNF169; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31] E 108516528 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HERC2-like K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] D Others E 108514362 WRAP53; telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1 E 108542867 TPRN; taperin K24164 TPRN; taperin E 108538149 ZCWPW1; zinc finger CW-type PWWP domain protein 1 isoform X1 K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1 E 108515979 WDR70; WD repeat-containing protein 70 isoform X1 K24752 WDR70; WD repeat-containing protein 70 E 108521300 WDR76; LOW QUALITY PROTEIN: WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76 B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D 108533518 POLH; DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7] D 108536329 POLI; DNA polymerase iota isoform X1 K03510 POLI; DNA polymerase iota [EC:2.7.7.7] D 108513078 POLK; LOW QUALITY PROTEIN: DNA polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7] D 108521504 REV1; DNA repair protein REV1 isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] C B-family DNA polymerases D 108512056 REV3L; LOW QUALITY PROTEIN: DNA polymerase zeta catalytic subunit K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] C A-family DNA polymerase D 108532292 POLN; LOW QUALITY PROTEIN: DNA polymerase nu K16618 POLN; DNA polymerase nu [EC:2.7.7.7] C Rad6 epistasis group D 108537571 UBE2A; ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D 108523192 ubiquitin-conjugating enzyme E2 A-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D 108529559 UBE2B; ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23] D 108530948 RAD18; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RAD18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27] D 108518300 HLTF; helicase-like transcription factor isoform X1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27] D 108535348 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant D 108539456 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant D 108523545 UBE2N; ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] D 108520651 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] D 108526191 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] D 108540037 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] D 108525735 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] C Other TLS factors D 108533343 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen D 108543131 PARPBP; PCNA-interacting partner isoform X1 K27412 PARPBP; PCNA-interacting partner D 108537848 SPRTN; sprT-like domain-containing protein Spartan isoform X1 K24051 SPRTN; SprT-like domain-contaning protein Spartan D 108523892 ACRC; acidic repeat-containing protein K26957 GCNA; germ cell nuclear acidic protein B Check point factors C Rad9-Hus1-Rad1 complex D 108518616 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] D 108512375 RAD9B; cell cycle checkpoint control protein RAD9B isoform X1 K10995 RAD9B; cell cycle checkpoint control protein RAD9B D 108527352 HUS1; checkpoint protein HUS1 isoform X1 K10903 HUS1; HUS1 checkpoint protein D 108514263 HUS1B; checkpoint protein HUS1B isoform X1 K10996 HUS1B; checkpoint protein HUS1B D 108543791 RAD1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C HRAD17(Rad24)-RFC complex D 108541169 RAD17; LOW QUALITY PROTEIN: cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein D 108526526 RFC2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4 D 108530459 RFC4; replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4 D 108539296 RFC5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5 D 108522735 RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5 C Rad17-Mec3-Ddc1 complex D 108543791 RAD1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C FPC (fork protection complex) D 108516064 TIMELESS; protein timeless homolog isoform X1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 D 108514674 TIPIN; TIMELESS-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 D 108537236 CLSPN; claspin K25773 CLSPN; claspin C Triple T complex D 108519381 TELO2; LOW QUALITY PROTEIN: telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein D 108519821 TTI1; TELO2-interacting protein 1 homolog isoform X1 K20403 TTI1; TELO2-interacting protein 1 D 108518771 TTI2; TELO2-interacting protein 2 K23115 TTI2; TELO2-interacting protein 2 C BAG6-UBL4A-GET4 complex D 108520245 BAG6; LOW QUALITY PROTEIN: large proline-rich protein BAG6 K23390 BAG6; large proline-rich protein BAG6 D 108518778 UBL4A; ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4 D 108528059 UBL4B; ubiquitin-like protein 4B K23388 UBL4; ubiquitin-like protein 4 D 108543613 GET4; Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4 C Other check point factors D 108535876 ATR; LOW QUALITY PROTEIN: serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] D 108527025 ATRIP; LOW QUALITY PROTEIN: ATR-interacting protein K10905 ATRIP; ATR interacting protein D 108517380 ATM; LOW QUALITY PROTEIN: serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] D 108514363 TP53; cellular tumor antigen p53 isoform X1 K04451 TP53; tumor protein p53 D 108542336 CHEK1; serine/threonine-protein kinase Chk1 isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] D 108517558 CHEK2; serine/threonine-protein kinase Chk2 isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] D 108517663 CDC25A; LOW QUALITY PROTEIN: M-phase inducer phosphatase 1 K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48] D 108533547 CDC25B; M-phase inducer phosphatase 2 isoform X1 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] D 108541696 CDC25C; LOW QUALITY PROTEIN: M-phase inducer phosphatase 3 K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48] D 108533372 YWHAB; 14-3-3 protein beta/alpha K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 108544549 LOW QUALITY PROTEIN: 14-3-3 protein zeta/delta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 108516257 YWHAQ; 14-3-3 protein theta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 108520193 YWHAZ; LOW QUALITY PROTEIN: 14-3-3 protein zeta/delta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 108527600 YWHAH; 14-3-3 protein eta isoform X1 K16198 YWHAG_H; 14-3-3 protein gamma/eta D 108518925 YWHAG; 14-3-3 protein gamma K16198 YWHAG_H; 14-3-3 protein gamma/eta D 108524248 YWHAE; 14-3-3 protein epsilon K06630 YWHAE; 14-3-3 protein epsilon D 108519364 NAV2; neuron navigator 2 isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] D 108541788 WEE1; LOW QUALITY PROTEIN: wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] D 108541546 WEE2; wee1-like protein kinase 2 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] D 108514376 PER1; LOW QUALITY PROTEIN: period circadian protein homolog 1 K21944 PER1; period circadian protein 1 D 108531921 PER2; period circadian protein homolog 2 isoform X1 K02633 PER2; period circadian protein 2 D 108517952 PER3; period circadian protein homolog 3 isoform X1 K21945 PER3; period circadian protein 3 D 108522549 MDC1; LOW QUALITY PROTEIN: mediator of DNA damage checkpoint protein 1 K20780 MDC1; mediator of DNA damage checkpoint protein 1 D 108512988 plastin-3-like K17336 PLS3; plastin-3 D 108535784 AEN; apoptosis-enhancing nuclease K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-] D 108535666 PLK3; serine/threonine-protein kinase PLK3 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21] D 108522544 inactive serine/threonine-protein kinase PLK5-like K19596 PLK5; inactive serine/threonine-protein kinase PLK5 D 108519338 NEK5; serine/threonine-protein kinase Nek5 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] D 108522327 NEK4; LOW QUALITY PROTEIN: serine/threonine-protein kinase Nek4 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] D 108522850 NEK1; serine/threonine-protein kinase Nek1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] D 108524740 NEK10; LOW QUALITY PROTEIN: serine/threonine-protein kinase Nek10 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1] D 108522241 NEK11; serine/threonine-protein kinase Nek11 isoform X1 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1] D 108536860 DONSON; LOW QUALITY PROTEIN: protein downstream neighbor of Son K22422 DONSON; protein downstream neighbor of Son D 108524213 KN motif and ankyrin repeat domain-containing protein 4 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 108527929 KANK2; KN motif and ankyrin repeat domain-containing protein 2 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 108532949 KANK4; KN motif and ankyrin repeat domain-containing protein 4 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 108534514 KANK3; LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 3 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 108536676 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 108527542 KLLN; LOW QUALITY PROTEIN: killin K23389 KLLN; killin D 108541459 SLFN11; LOW QUALITY PROTEIN: schlafen family member 11 K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-] D 108519736 CHMP4C; charged multivesicular body protein 4c K24782 CHMP4C; charged multivesicular body protein 4C D 108514504 vacuolar protein sorting-associated protein 4A isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4 D 108526371 VPS4B; vacuolar protein sorting-associated protein 4B K12196 VPS4; vacuolar protein-sorting-associated protein 4 D 108523414 ZFYVE19; abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator D 108538755 SDE2; protein SDE2 homolog K25059 SDE2; replication stress response regulator SDE2 B Other factors with a suspected DNA repair function C DNA polymerases D 108541638 POLQ; DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7] D 108520726 MYBBP1A; LOW QUALITY PROTEIN: myb-binding protein 1A K02331 POL5; DNA polymerase phi [EC:2.7.7.7] D 108515614 PRIMPOL; LOW QUALITY PROTEIN: DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7] C Nucleases D 108527023 TREX1; three-prime repair exonuclease 1 K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] D 108535092 TREX2; three prime repair exonuclease 2 K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2] D 108542459 DCLRE1A; DNA cross-link repair 1A protein isoform X1 K15340 DCLRE1A; DNA cross-link repair 1A protein D 108528112 DCLRE1B; 5' exonuclease Apollo K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-] D 108530398 EXO5; exonuclease V K17815 EXO5; exonuclease V [EC:3.1.-.-] D 108534143 ENDOV; endonuclease V isoform X1 K21813 ENDOV; endonuclease V [EC:3.1.26.-] D 108539637 ZRANB3; LOW QUALITY PROTEIN: DNA annealing helicase and endonuclease ZRANB3 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-] D 108534291 ANKLE1; ankyrin repeat and LEM domain-containing protein 1 isoform X1 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1 C Helicases D 108531150 HELQ; helicase POLQ-like isoform X1 K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] D 108529287 ERCC6L2; LOW QUALITY PROTEIN: DNA excision repair protein ERCC-6-like 2 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-] C PSO4 complex D 108528779 PRPF19; pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] D 108533516 CDC5L; LOW QUALITY PROTEIN: cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 D 108528117 BCAS2; pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27 D 108529037 PLRG1; pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1 C Modulation of nucleotide pools D 108530748 NUDT15; probable 8-oxo-dGTP diphosphatase NUDT15 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D 108543779 NUDT1; LOW QUALITY PROTEIN: 7,8-dihydro-8-oxoguanine triphosphatase K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] D 108521324 NUDT18; 8-oxo-dGDP phosphatase NUDT18 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D 108530110 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D 108543724 RRM1; ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] D 108516338 RRM2; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] D 108520195 RRM2B; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D 108519589 MGMT; methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E 108534404 UNG; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E 108514631 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] E 108521112 MPG; DNA-3-methyladenine glycosylase isoform X1 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E 108535656 MUTYH; adenine DNA glycosylase isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E 108519400 NTHL1; endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D RecJ D DNA ligase D DNA polymerase I C NER (nucleotide excision repair) D GGR (global genome repair) factors D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) E TRCF (transcription-repair coupling factor) C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases D DNA polymerase III holoenzyme D DNA ligase D Other MMR factors E 108541548 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X1 K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins D RecFOR pathway proteins D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator E Supressor D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway E Facilitator E Supressor B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C Other SOS response factors D 108541548 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X1 K03111 ssb; single-strand DNA-binding protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases C Modulation of nucleotide pools D 108530748 NUDT15; probable 8-oxo-dGTP diphosphatase NUDT15 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D 108530110 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024