+C Secretion system KO
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Secretion System - Cupriavidus metallidurans
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AType I secretion system
B alpha-Hemolysin/cyclolysin transporter
C Rmet_2711 Type I secretion outer membrane efflux protein (TolC-like) K12340 tolC; outer membrane protein
C Rmet_4512 outer membrane efflux protein K12340 tolC; outer membrane protein
B RTX toxin transporter
C Rmet_2711 Type I secretion outer membrane efflux protein (TolC-like) K12340 tolC; outer membrane protein
C Rmet_4512 outer membrane efflux protein K12340 tolC; outer membrane protein
B Multiple protein transporter
C Rmet_2711 Type I secretion outer membrane efflux protein (TolC-like) K12340 tolC; outer membrane protein
C Rmet_4512 outer membrane efflux protein K12340 tolC; outer membrane protein
B Adhesin protein transporter
B RaxAB-RaxC type I secretion system protein
C Rmet_2711 Type I secretion outer membrane efflux protein (TolC-like) K12340 tolC; outer membrane protein
C Rmet_4512 outer membrane efflux protein K12340 tolC; outer membrane protein
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AType II secretion system
B General secretion pathway protein
C Rmet_3381 gspC; general secretion pathway related transmembrane protein K02452 gspC; general secretion pathway protein C
C Rmet_3392 gspD; general secretory pathway component, cryptic K02453 gspD; general secretion pathway protein D
C Rmet_4706 Putative secretion type II protein; gspD(secretin)-like protein K02453 gspD; general secretion pathway protein D
C Rmet_3393 gspE; general secretory pathway component, cryptic K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
C Rmet_4711 gspE; type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
C Rmet_3394 gspF; general secretory pathway component, cryptic K02455 gspF; general secretion pathway protein F
C Rmet_4712 gspF; Type II secretory pathway, gspf-related transmembrane protein K02455 gspF; general secretion pathway protein F
C Rmet_3384 gspG; pseudopilin, cryptic, general secretion pathway K02456 gspG; general secretion pathway protein G
C Rmet_4704 Type II secretion system protein G K02456 gspG; general secretion pathway protein G
C Rmet_4705 Putative secretion type II protein related to protein G K02456 gspG; general secretion pathway protein G
C Rmet_4713 gspG; General secretion pathway protein G K02456 gspG; general secretion pathway protein G
C Rmet_4795 putative general (Type II) secretion pathway protein K02456 gspG; general secretion pathway protein G
C Rmet_3385 gspH; general secretion pathway protein H K02457 gspH; general secretion pathway protein H
C Rmet_3386 gspI; general secretion pathway protein I K02458 gspI; general secretion pathway protein I
C Rmet_3387 gspJ; general secretion pathway protein J K02459 gspJ; general secretion pathway protein J
C Rmet_3388 gspK; general secretion pathway protein K K02460 gspK; general secretion pathway protein K
C Rmet_3389 gspL; general secretion pathway protein L K02461 gspL; general secretion pathway protein L
C Rmet_3390 gspM; general secretion pathway protein M K02462 gspM; general secretion pathway protein M
C Rmet_3391 gspN; general secretion pathway protein N K02463 gspN; general secretion pathway protein N
C Rmet_3110 pilD; Type IV pilus prepilin leader peptidase 1 K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
B Pilin secretion/fimbrial assembly protein
C Rmet_0472 pilA; Type IV pilus structural subunit PilA K02650 pilA; type IV pilus assembly protein PilA
C Rmet_0473 pilE; Fimbrial protein precursor (Pilin) (Strain P1) K02650 pilA; type IV pilus assembly protein PilA
C Rmet_0697 pilA; Type IV pilus structural subunit PilA K02650 pilA; type IV pilus assembly protein PilA
C Rmet_3108 pilB; Type IV pilus assembly protein PilB K02652 pilB; type IV pilus assembly protein PilB
C Rmet_3109 pilC; Type IV pilus assembly protein PilC K02653 pilC; type IV pilus assembly protein PilC
C Rmet_3110 pilD; Type IV pilus prepilin leader peptidase 1 K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C Rmet_0193 putative Type-4 pilus assembly protein PilE (pilE1) K02655 pilE; type IV pilus assembly protein PilE
C Rmet_2686 putative Type IV pilus assembly protein (PilE-like) K02655 pilE; type IV pilus assembly protein PilE
C Rmet_5684 pilE; pilus assembly protein, PilE K02655 pilE; type IV pilus assembly protein PilE
C Rmet_2108 pilF; Type IV pilus biogenesis protein PilF K02656 pilF; type IV pilus assembly protein PilF
C Rmet_0669 pilG; Type IV pilus response regulator PilG K02657 pilG; twitching motility two-component system response regulator PilG
C Rmet_0670 pilH; Type IV pilus response regulator PilH K02658 pilH; twitching motility two-component system response regulator PilH
C Rmet_0671 pilI; Type IV pilus signal transduction protein PilI K02659 pilI; twitching motility protein PilI
C Rmet_0672 pilJ; Type IV pilus transmembrane protein PilJ K02660 pilJ; twitching motility protein PilJ
C Rmet_3272 pilM; Type IV pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM
C Rmet_3271 pilN; tfp pilus assembly protein PilN K02663 pilN; type IV pilus assembly protein PilN
C Rmet_3270 pilO; Type IV pilus assembly protein PilO K02664 pilO; type IV pilus assembly protein PilO
C Rmet_3269 pilP; Type IV pilus assembly protein PilP K02665 pilP; type IV pilus assembly protein PilP
C Rmet_3268 pilQ; pili assembly protein PilQ K02666 pilQ; type IV pilus assembly protein PilQ
C Rmet_2936 pilT; PilT, Type IV pilus twitching motility protein K02669 pilT; twitching motility protein PilT
C Rmet_2935 pilU; PilU, Type IV pilus twitching motility protein K02670 pilU; twitching motility protein PilU
C Rmet_0189 putative type-4 fimbrial biogenesis pilV transmembrane protein K02671 pilV; type IV pilus assembly protein PilV
C Rmet_5686 pilV; Type IV fimbrial biogenesis, pilV-related transmembrane protein K02671 pilV; type IV pilus assembly protein PilV
C Rmet_0190 putative type 4 fimbrial biogenesis transmembrane protein, pilW K02672 pilW; type IV pilus assembly protein PilW
C Rmet_2683 putative Type VI pilus assembly protein (PilW-like) K02672 pilW; type IV pilus assembly protein PilW
C Rmet_5687 pilW; Type IV fimbrial biogenesis pilW-related transmembrane protein K02672 pilW; type IV pilus assembly protein PilW
C Rmet_0191 putative type-4 fimbrial biogenesis transmembrane protein, pilX K02673 pilX; type IV pilus assembly protein PilX
C Rmet_5688 conserved hypothetical protein; putative pilin biogenesis Transmembrane protein (pilin operon) K02673 pilX; type IV pilus assembly protein PilX
C Rmet_0192 putative type-4 fimbrial biogenesis pilY1-related protein K02674 pilY1; type IV pilus assembly protein PilY1
C Rmet_2685 putative Type IV pilus assembly protein, tip-associated adhesin (PilY1-like) K02674 pilY1; type IV pilus assembly protein PilY1
C Rmet_5689 pilY1; PilY1, Type IV fimbrial biogenesis protein (signal peptide) K02674 pilY1; type IV pilus assembly protein PilY1
C Rmet_1826 pilZ; type IV fimbrial biogenesis protein PilZ K02676 pilZ; type IV pilus assembly protein PilZ
C Rmet_0188 putative type-4 fimbrial pilin related signal peptide protein K08084 fimT; type IV fimbrial biogenesis protein FimT
C Rmet_2687 putative Type IV pili related protein K08084 fimT; type IV fimbrial biogenesis protein FimT
C Rmet_5685 fimT; Type IV pilus transmembrane protein, FimT K08084 fimT; type IV fimbrial biogenesis protein FimT
C Rmet_2470 type IV-pili assembly fimV-related transmembrane protein K08086 fimV; pilus assembly protein FimV
B Tight adherence (Tad) export apparatus
C Rmet_0650 cpaA1; flp pilus assembly leader peptidase CpaA K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
C Rmet_0648 cpaB1; Flp pilus assembly CpaB precursor K02279 cpaB; pilus assembly protein CpaB
C Rmet_3653 cpaB; pilus assembly protein K02279 cpaB; pilus assembly protein CpaB
C Rmet_0647 cpaC1; Flp pilus assembly protein secretin CpaC K02280 cpaC; pilus assembly protein CpaC
C Rmet_3654 cpaC; pilus assembly protein K02280 cpaC; pilus assembly protein CpaC
C Rmet_0642 cpaE1; flp pilus assembly ATPase K02282 cpaE; pilus assembly protein CpaE
C Rmet_3655 cpaE2; pilus assembly protein K02282 cpaE; pilus assembly protein CpaE
C Rmet_0641 cpaF1; flp pilus assembly ATPase CpaF K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
C Rmet_3656 tadA; type II/IV secretion system protein, ATPase domain protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
C Rmet_0640 tadB; flp pilus assembly protein TadB K12510 tadB; tight adherence protein B
C Rmet_3657 tadB; type II secretion system protein, pilus assembly, transmembrane part K12510 tadB; tight adherence protein B
C Rmet_0639 tadC; Bacterial type II secretion system protein, probably involved in Flp pilus synthesis K12511 tadC; tight adherence protein C
C Rmet_3658 tadC; type II secretion system protein, transmembrane K12511 tadC; tight adherence protein C
C Rmet_3659 tadD; flp pilus assembly protein (TPR domain), transmembrane K27079 tadD; tight adherence protein D
C Rmet_0643 flp pilus assembly protein (TadG-like) K12513 tadE; tight adherence protein E
C Rmet_0644 flp pilus assembly protein (TadG-like) K12513 tadE; tight adherence protein E
C Rmet_3652 putative tight adherence (TadE/G) protein K12513 tadE; tight adherence protein E
C Rmet_3661 conserved hypothetical protein K27080 tadG; tight adherence protein G
C Rmet_0651 pilA; Flp/Fap pilin component; Putative pilus subunit protein K02651 flp; pilus assembly protein Flp/PilA
C Rmet_0652 pilA; Flp/Fap pilin component; Putative pilus subunit protein K02651 flp; pilus assembly protein Flp/PilA
C Rmet_0653 pilA; Flp/Fap pilin component; Putative pilus subunit protein K02651 flp; pilus assembly protein Flp/PilA
C Rmet_3651 pilA; Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
B Toxin co-regulated pilus biosynthesis protein
B MSHA pilus biogenesis protein
B Type IVa pilus homolog protein
C Rmet_3110 pilD; Type IV pilus prepilin leader peptidase 1 K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C Rmet_2936 pilT; PilT, Type IV pilus twitching motility protein K02669 pilT; twitching motility protein PilT
C Rmet_3642 conserved hypothetical protein K02221 yggT; YggT family protein
B Archaeal flagellar protein
B Competence-related DNA transformation transporter (DNA-T) core components
C Rmet_0729 conserved hypothetical protein; putative exported protein K02237 comEA; competence protein ComEA
C Rmet_1043 DNA internalization-related competence protein ComEC/Rec2 K02238 comEC; competence protein ComEC
B Competence-related DNA transformation transporter (DNA-T) related proteins
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AType III secretion system
B Type III secretion core apparatus
B Type III secretion related proteins
B Flagellar export apparatus
C Rmet_3699 flhA; flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA
C Rmet_3698 flhB; flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB
C Rmet_5258 putative flagellar protein K04061 flhB2; flagellar biosynthesis protein
C Rmet_5261 fliF; flagellar MS-ring protein K02409 fliF; flagellar M-ring protein FliF
C Rmet_5263 fliH; flagellar assembly protein H K02411 fliH; flagellar assembly protein FliH
C Rmet_5264 fliI; flagellum-specific ATP synthase K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]
C Rmet_5299 fliN; Flagellar motor switch FliN K02417 fliN; flagellar motor switch protein FliN
C Rmet_5300 fliO; flagellar biosynthesis protein, FliO K02418 fliO; flagellar protein FliO/FliZ
C Rmet_5301 fliP; flagellar biosynthesis protein FliP K02419 fliP; flagellar biosynthesis protein FliP
C Rmet_5302 fliQ; flagellar biosynthesis protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ
C Rmet_5303 fliR; flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR
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AType IV secretion system
B Conjugal DNA-protein transfer (VirB/D) protein
B DNA uptake competence system protein
B Conjugal transfer pilus assembly protein
C Rmet_2290 soj; ATPase involved in plasmid partitioning Soj K12055 K12055; chromosome partitioning related protein ParA
C Rmet_6166 trbC; Type-F conjugative transfer system pilin assembly protein TrbC K12059 trbC; conjugal transfer pilus assembly protein TrbC
C Rmet_6167 traU; TraU sex pilus assembly and synthesis protein K12060 traU; conjugal transfer pilus assembly protein TraU
C Rmet_6168 traW; Type-F conjugative transfer system protein TraW; sex pilus assembly and synthesis protein K12061 traW; conjugal transfer pilus assembly protein TraW
C Rmet_2364 relaxase K12070 traI; conjugal transfer pilus assembly protein TraI
C Rmet_6308 traI; Conjugative transfer protein, possible DNA relaxase K12070 traI; conjugal transfer pilus assembly protein TraI
C Rmet_2336 virD4; VirD4, Type IV secretory pathway, VirD4 components K12071 traD; conjugal transfer pilus assembly protein TraD
C Rmet_6309 traG; channel-forming protein, conjugal transfer protein K12071 traD; conjugal transfer pilus assembly protein TraD
C Rmet_3190 dsbC; Protein-disulfide isomerase K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
C Rmet_6169 dsbC; thiol-disulfide isomerase K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
B Pertussis toxin exporter
B Cag pathogenicity island (PAI) protein
B Icm/Dot secretion system protein
B Trb secretion system protein
C Rmet_1341 trbB; P-type conjugative transfer ATPase TrbB (CMGI-2) K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8]
C Rmet_1550 trbB; P-type conjugative transfer ATPase TrbB (CMGI-2) K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8]
C Rmet_1342 trbC; conjugal transfer TrbC transmembrane protein (CMGI-2) K20528 trbC; type IV secretion system protein TrbC
C Rmet_1551 trbC; mating pair formation conjugal transfer TrbC transmembrane protein (module transfer of genomic island CMGI-3) K20528 trbC; type IV secretion system protein TrbC
C Rmet_1343 trbD; conjugal transfer TrbD transmembrane protein (protein belongs to CMGI-2) K20529 trbD; type IV secretion system protein TrbD
C Rmet_1552 trbD; putative conjugal transfer transmembrane protein K20529 trbD; type IV secretion system protein TrbD
C Rmet_6304 trbD; Conjugal transfer protein K20529 trbD; type IV secretion system protein TrbD
C Rmet_1344 trbE; ATPase involved in conjugal transfer CagE TrbE VirB component of type IV transporter system (protein belongs to CMGI-2) K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8]
C Rmet_1553 trbE; ATPase involved in conjugal transfer CagE TrbE VirB component of type IV transporter system (belongs to transfer module of genomic island CMGI-3) K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8]
C Rmet_6305 trbE; Conjugal transfer protein K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8]
C Rmet_1348 trbF; conjugal transfer trbF precursor (protein belongs to CMGI-2) K20531 trbF; type IV secretion system protein TrbF
C Rmet_1557 trbF; conjugal transfer precursor protein K20531 trbF; type IV secretion system protein TrbF
C Rmet_6301 trbF; Conjugal transfer precursor (VirB8-like protein) K20531 trbF; type IV secretion system protein TrbF
C Rmet_1349 trbG; Conjugal transfer protein TrbG/VirB9/CagX precursor putative exported protein(protein belongs to CMGI-2) K20532 trbG; type IV secretion system protein TrbG
C Rmet_1558 trbG; Conjugal transfer protein precursor K20532 trbG; type IV secretion system protein TrbG
C Rmet_6300 trbG; Mating pair formation K20532 trbG; type IV secretion system protein TrbG
C Rmet_1350 trbI; type IV secretion system transmembrane protein (conjugal transfer:mating pair formation) (protein belongs to CMGI-2) K20533 trbI; type IV secretion system protein TrbI
C Rmet_1559 trbI; type IV secretion system transmembrane protein (conjugal transfer:mating pair formation) K20533 trbI; type IV secretion system protein TrbI
C Rmet_6299 trbI; Conjugal transfer protein K20533 trbI; type IV secretion system protein TrbI
C Rmet_1345 trbJ; conjugal transfer TrbJ signal peptide protein (protein belongs to CMGI-2) K20266 trbJ; type IV secretion system protein TrbJ
C Rmet_1554 trbJ; mating pair formation protein K20266 trbJ; type IV secretion system protein TrbJ
C Rmet_6306 trbJ; conjugal transfer protein (entry exclusion, mating pair formation) K20266 trbJ; type IV secretion system protein TrbJ
C Rmet_1347 trbL; conjugal transfer trbL transmembrane protein (protein belongs to CMGI-2) K07344 trbL; type IV secretion system protein TrbL
C Rmet_1556 trbL; conjugal transfer transmembrane protein K07344 trbL; type IV secretion system protein TrbL
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AType V secretion system
B Autotransporter-1 (AT-1) family
B Autotransporter-2 (AT-2) family
B Two-partner secretion (TPS) family
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AType VI secretion system
B Imp/Vas secretion system core components
C Rmet_0633 conserved hypothetical protein K11891 impL; type VI secretion system protein ImpL
C Rmet_0621 conserved hypothetical protein K11892 impK; type VI secretion system protein ImpK
C Rmet_0622 conserved hypothetical protein K11893 impJ; type VI secretion system protein ImpJ
C Rmet_0636 conserved hypothetical protein K11895 impH; type VI secretion system protein ImpH
C Rmet_0635 conserved hypothetical protein K11896 impG; type VI secretion system protein ImpG
C Rmet_0624 conserved hypothetical protein K11900 impC; type VI secretion system protein ImpC
C Rmet_0625 conserved hypothetical protein K11901 impB; type VI secretion system protein ImpB
C Rmet_0619 conserved hypothetical protein K11903 hcp; type VI secretion system secreted protein Hcp
C Rmet_0626 Rhs element Vgr protein K11904 vgrG; type VI secretion system secreted protein VgrG
C Rmet_4796 Rhs element Vgr protein K11904 vgrG; type VI secretion system secreted protein VgrG
C Rmet_0617 conserved hypothetical protein K11905 K11905; type VI secretion system protein
C Rmet_0637 conserved hypothetical protein; putative exported protein K11906 vasD; type VI secretion system protein VasD
C Rmet_0618 clpB; Chaperone clpB (Heat-shock protein F84.1) K11907 vasG; type VI secretion system protein VasG
C Rmet_0634 ImpA, N-terminal K11910 vasJ; type VI secretion system protein VasJ
B Imp/Vas secretion system related proteins
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AType VII secretion system
B ESX secretion system protein
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AChaperone-usher system
B Type 1 pilus assembly protein
C Rmet_0576 fimA; Type-1 fimbrial protein subunit precursor K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_1667 fimA; Fimbrial protein K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_2545 putative fimbrial protein K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_4005 hypothetical protein K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_4250 fimA; major type 1 subunit fimbrin (pilin) K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_4253 Fimbrial protein K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_4958 Fimbrial protein K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_4961 fimA; Fimbrial protein K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_5116 fimbrial protein K07345 fimA; major type 1 subunit fimbrin (pilin)
C Rmet_0574 htrE; Fimbrial biogenesis outer membrane usher K07347 fimD; outer membrane usher protein
C Rmet_1665 papC; outer membrane usher protein precursor(fimbrial usher protein) K07347 fimD; outer membrane usher protein
C Rmet_4252 htrE; fimbrial biogenesis outer membrane usher protein K07347 fimD; outer membrane usher protein
C Rmet_4959 fimD; fimbrial biogenesis outer membrane usher protein K07347 fimD; outer membrane usher protein
B P pilus assembly protein
B Mat/Ecp fimbriae assembly protein
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AExtracellular nucleation-precipitation pathway
B Curli assembly protein
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ASec (secretion) system
B Prokaryotic Sec-SRP core components
C Rmet_3118 secA; preprotein translocase subunit, ATPase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
C Rmet_0254 secB; protein export chaperone K03071 secB; preprotein translocase subunit SecB
C Rmet_2946 secD; SecYEG protein translocase auxiliary subunit K03072 secD; preprotein translocase subunit SecD
C Rmet_3340 secE; preprotein translocase membrane subunit K03073 secE; preprotein translocase subunit SecE
C Rmet_2947 secF; SecYEG protein translocase auxiliary subunit K03074 secF; preprotein translocase subunit SecF
C Rmet_0926 secG; preprotein translocase membrane subunit K03075 secG; preprotein translocase subunit SecG
C Rmet_3297 secY; preprotein translocase membrane subunit K03076 secY; preprotein translocase subunit SecY
C Rmet_3094 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C Rmet_0281 ftsY; probable cell division protein; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
C Rmet_2945 yajC; preprotein translocase auxiliary subunit YajC transmembrane K03210 yajC; preprotein translocase subunit YajC
C Rmet_3613 yidC; inner membrane insertion protein YidC/OxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase
B Prokaryotic Sec-SRP related proteins
B Eukaryotic Sec-SRP protein
C Rmet_3094 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
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ATwin-arginine translocation (Tat) system
B Twin-arginine translocation (Tat) pathway protein
C Rmet_3237 tatA; TatABCE protein translocation system subunit K03116 tatA; sec-independent protein translocase protein TatA
C Rmet_3236 tatB; Sec-independent protein translocase component TatB K03117 tatB; sec-independent protein translocase protein TatB
C Rmet_3235 tatC; TatABCE protein translocation system subunit K03118 tatC; sec-independent protein translocase protein TatC
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 14, 2025