+F Repair protein KO
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DNA Repair and Recombination Proteins - Ralstonia mannitolilytica
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D TK49_15745 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D TK49_15955 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D TK49_07420 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E TK49_00080 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TK49_05065 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E TK49_09260 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D TK49_06245 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D TK49_15610 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D TK49_15745 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D TK49_15955 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D TK49_16070 6-O-methylguanine DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D TK49_07420 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D TK49_19515 deoxyribodipyrimidine photolyase K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D TK49_16060 alpha-ketoglutarate-dependent dioxygenase K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E TK49_00080 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E TK49_18440 2-hydroxyacid dehydrogenase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E TK49_10985 DNA polymerase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E TK49_09930 Fe-S cluster assembly protein HesB K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TK49_16065 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TK49_15740 Ada K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E TK49_05065 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E TK49_17330 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E TK49_05055 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E TK49_09260 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E TK49_12395 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E TK49_03790 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E TK49_09695 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E TK49_11125 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E TK49_14605 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E TK49_05160 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E TK49_22305 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E TK49_09285 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E TK49_09585 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E TK49_21060 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E TK49_07715 damage-inducible protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E TK49_14630 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E TK49_14605 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E TK49_11125 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F TK49_00820 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F TK49_00815 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F TK49_00605 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F TK49_23470 hypothetical protein K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F TK49_14190 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F TK49_12150 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E TK49_09875 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E TK49_16040 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E TK49_01550 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E TK49_15875 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E TK49_14565 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E TK49_14435 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E TK49_03595 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E TK49_15345 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E TK49_06720 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E TK49_11525 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E TK49_13295 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E TK49_10065 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E TK49_11125 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E TK49_21060 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E TK49_07715 damage-inducible protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E TK49_14630 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E TK49_05170 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E TK49_07710 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E TK49_06870 recA; recombinase A K03553 recA; recombination protein RecA
E TK49_05585 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E TK49_05580 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E TK49_05595 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E TK49_02310 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E TK49_10690 primosomal replication protein N K02686 priB; primosomal replication protein N
E TK49_01550 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E TK49_06870 recA; recombinase A K03553 recA; recombination protein RecA
E TK49_11000 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E TK49_06010 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E TK49_09695 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E TK49_09555 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E TK49_10080 recR; recombination protein RecR K06187 recR; recombination protein RecR
E TK49_16225 DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E TK49_18970 recombinase RdgC K03554 rdgC; recombination associated protein RdgC
E TK49_05585 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E TK49_05580 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E TK49_05595 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E TK49_10060 ATP-dependent exonuclease K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E TK49_10055 recombinase RecB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E TK49_14345 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E TK49_07025 DNA repair protein K10979 ku; DNA end-binding protein Ku
E TK49_07020 ligD; ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F TK49_08775 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F TK49_03600 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F TK49_03545 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F TK49_02615 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F TK49_11975 transcriptional regulator HU subunit alpha K03530 hupB; DNA-binding protein HU-beta
F TK49_22965 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
F TK49_15830 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F TK49_09695 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F TK49_09555 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F TK49_10080 recR; recombination protein RecR K06187 recR; recombination protein RecR
F TK49_11125 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F TK49_05605 Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F TK49_12480 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F TK49_08815 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F TK49_01550 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F TK49_00775 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F TK49_05160 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F TK49_22305 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F TK49_09285 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F TK49_18200 DNA-binding protein K03746 hns; DNA-binding protein H-NS
F TK49_23465 hypothetical protein K03746 hns; DNA-binding protein H-NS
F TK49_21835 endonuclease K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D TK49_12450 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D TK49_06870 recA; recombinase A K03553 recA; recombination protein RecA
D TK49_10670 LexA family transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88]
D TK49_16405 peptidase S24 K01356 lexA; repressor LexA [EC:3.4.21.88]
D TK49_16225 DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D TK49_17040 cell division protein K14160 imuA; protein ImuA
D TK49_17035 DNA polymerase IV protein K14161 imuB; protein ImuB
D TK49_17030 DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D TK49_05170 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D TK49_07710 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D TK49_06875 recombinase RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D TK49_02200 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D TK49_12235 helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D TK49_19680 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D TK49_06245 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D TK49_15610 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D TK49_06395 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D TK49_06400 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024