+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Roseimicrobium sp. ORNL1</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
D      G5S37_09090 hypothetical protein	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] 
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
D      G5S37_09090 hypothetical protein	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] 
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
D      G5S37_14190 hypothetical protein	K07061 cmr1; CRISPR-associated protein Cmr1 
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    G5S37_26330 DEAD/DEAH box helicase family protein	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    G5S37_26345 hypothetical protein	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    G5S37_09000 N-6 DNA methylase	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      G5S37_27840 site-specific DNA-methyltransferase	K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] 
B  Type III R-M system
C    G5S37_27955 DEAD/DEAH box helicase family protein	K01156 res; type III restriction enzyme [EC:3.1.21.5] 
C    G5S37_27960 site-specific DNA-methyltransferase	K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72] 
B  Type IV R-M system
C    G5S37_13155 hypothetical protein	K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      G5S37_06215 type II toxin-antitoxin system RelE/ParE family toxin	K19092 parE1_3_4; toxin ParE1/3/4 
D      G5S37_07595 type II toxin-antitoxin system RelE/ParE family toxin	K19092 parE1_3_4; toxin ParE1/3/4 
D      G5S37_07600 type II toxin-antitoxin system ParD family antitoxin	K07746 parD1_3_4; antitoxin ParD1/3/4 
D      G5S37_25095 hypothetical protein	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
D      G5S37_29260 type II toxin-antitoxin system death-on-curing family toxin	K07341 doc; death on curing protein 
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      G5S37_32040 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      G5S37_32120 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
D      G5S37_24000 hypothetical protein	K21495 fitA; antitoxin FitA 
C    BC_0920-BC_0921
C    Type II TA system related factors
D      G5S37_21095 hypothetical protein	K03531 ftsZ; cell division protein FtsZ 
D      G5S37_13060 rod shape-determining protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      G5S37_16300 DNA gyrase/topoisomerase IV subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      G5S37_16350 type IIA DNA topoisomerase subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    G5S37_23135 cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    G5S37_28985 cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023