+F Repair protein KO
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DNA Repair and Recombination Proteins - Ralstonia solanacearum CMR15
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CMR15_10872 ogt; Methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CMR15_10817 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CMR15_10527 ung; uracil-DNA-glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CMR15_30505 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CMR15_20120 nth; endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase, acts on 5-formyluracil and 5-hydroxymethyluracil K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D CMR15_10584 mutT; Mutator mutT protein (7, 8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CMR15_mp20067 putative thiamine-phosphate pyrophosphorylase (thiE) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CMR15_10914 dut; deoxyuridinetriphosphatase (dUTP diphosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CMR15_10872 ogt; Methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CMR15_10817 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CMR15_10790 ada; fused DNA-binding transcriptional dual regulator; O6-methylguanine-DNA methyltransferase; (AraC/Xyl family) (N-terminal); bifunctional K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D CMR15_10792 alkB; Alpha-ketoglutarate-dependent dioxygenase alkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E CMR15_10527 ung; uracil-DNA-glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CMR15_20579 ung; uracil-DNA glycosylase,phage-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E CMR15_10791 alkA; na-3-methyladenine glycosylase protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CMR15_20374 putative DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CMR15_10873 Putative regulatory protein ada (Regulatory protein of adaptative response) [Includes: Methylated-DNA--protein-cysteine methyltransferase (O-6-methylguanine-DNA alkyltransferase)] K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CMR15_30505 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CMR15_mp10634 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E CMR15_30507 mutM; formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E CMR15_20120 nth; endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase, acts on 5-formyluracil and 5-hydroxymethyluracil K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CMR15_11591 xthA; EXODEOXYRIBONUCLEASE III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E CMR15_30768 putative exodeoxyribonuclease III/endonuclease/phosphatase K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E CMR15_20319 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E CMR15_20609 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E CMR15_11146 polA; DNA polymerase I (POL I) K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CMR15_30486 uvrA; ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC K03701 uvrA; excinuclease ABC subunit A
E CMR15_mp20075 uvrA; Excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E CMR15_20126 uvrB; ATP-dependent DNA excision repair enzyme, DNA damage recognition component K03702 uvrB; excinuclease ABC subunit B
E CMR15_20189 uvrC; UvrABC system protein C (Excinuclease ABC subunit C) K03703 uvrC; excinuclease ABC subunit C
E CMR15_11141 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CMR15_mp20379 putative atp-dependent dna helicase II protein (uvrD) K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CMR15_11146 polA; DNA polymerase I (POL I) K02335 polA; DNA polymerase I [EC:2.7.7.7]
E CMR15_20609 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F CMR15_10360 rpoB; RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F CMR15_10361 rpoC; RNA polymerase, beta prime subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F CMR15_10401 rpoA; RNA polymerase, alpha subunit; RNA polymerase alpha chain family K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F CMR15_11230 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F CMR15_11644 mfd; transcription-repair ATP-dependent coupling factor, helicase K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CMR15_20356 mutS; methyl-directed DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E CMR15_10797 mutL; methyl-directed mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E CMR15_10275 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E CMR15_10846 xseA; exonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E CMR15_11173 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E CMR15_10002 dnaN; DNA polymerase III, beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CMR15_10965 holC; DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E CMR15_10671 holA; DNA-directed DNA polymerase, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E CMR15_11789 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E CMR15_11454 dnaQ; DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CMR15_20397 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E CMR15_20609 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E CMR15_11141 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CMR15_mp20379 putative atp-dependent dna helicase II protein (uvrD) K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CMR15_30484 ssb; ssDNA-binding protein, controls activity of RecBCD nuclease K03111 ssb; single-strand DNA-binding protein
E CMR15_p0023 vsr; DNA mismatch endonuclease of very short patch repair K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E CMR15_30576 protein of unknown function, P-loop containing nucleoside triphosphate hydrolases K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CMR15_30349 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
E CMR15_30403 ruvA; subunit A of RuvABC Holliday junction resolvasome, regulatory subunit K03550 ruvA; holliday junction DNA helicase RuvA
E CMR15_30404 ruvB; ATP-dependent DNA helicase, subunit B of RuvABC Holliday junction resolvasome K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CMR15_30401 ruvC; endodeoxyribonuclease, subunit C of RuvABC Holliday junction resolvasome K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E CMR15_10164 priA; Primosome factor n' (replication factor Y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E CMR15_20516 putative rimosomal replication protein N (priB) K02686 priB; primosomal replication protein N
E CMR15_10275 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E CMR15_30349 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
E CMR15_20582 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E CMR15_10705 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CMR15_20319 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E CMR15_20183 recO; DNA repair protein recO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
E CMR15_20399 recR; Recombination protein recR K06187 recR; recombination protein RecR
E CMR15_10761 recN; DNA repair protein recN (Recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N)
E CMR15_30278 rdgC; Recombination associated protein K03554 rdgC; recombination associated protein RdgC
E CMR15_30403 ruvA; subunit A of RuvABC Holliday junction resolvasome, regulatory subunit K03550 ruvA; holliday junction DNA helicase RuvA
E CMR15_30404 ruvB; ATP-dependent DNA helicase, subunit B of RuvABC Holliday junction resolvasome K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CMR15_30401 ruvC; endodeoxyribonuclease, subunit C of RuvABC Holliday junction resolvasome K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E CMR15_20396 putative helicase, uvrD subfamily K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E CMR15_20395 putative helicase, C_term RecB family exonuclease K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E CMR15_11190 putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F CMR15_20018 gyrA; DNA gyrase, subunit A, type II topoisomerase K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CMR15_10003 gyrB; DNA gyrase, subunit B (type II topoisomerase) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F CMR15_10109 hupB; DNA-binding protein HU-beta, NS1 (HU-1), plays a role in DNA replication and in rpo translation K03530 hupB; DNA-binding protein HU-beta
F CMR15_10854 hupB; DNA-binding protein HU-beta, NS1 (HU-1), plays a role in DNA replication and in rpo translation K03530 hupB; DNA-binding protein HU-beta
F CMR15_11727 hupB; DNA-binding protein HU-beta, transcriptional regulator, beta subunit K03530 hupB; DNA-binding protein HU-beta
F CMR15_mp10395 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F CMR15_20319 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F CMR15_20183 recO; DNA repair protein recO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
F CMR15_20399 recR; Recombination protein recR K06187 recR; recombination protein RecR
F CMR15_20609 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F CMR15_30399 putative transcriptional regulator, FIS family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F CMR15_11581 ihfA; integration host factor (IHF), alpha subunit K04764 ihfA; integration host factor subunit alpha
F CMR15_20027 ihfB; Integration host factor subunit beta (IHF-beta) K05788 ihfB; integration host factor subunit beta
E Supressor
F CMR15_10275 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F CMR15_10369 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F CMR15_30486 uvrA; ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC K03701 uvrA; excinuclease ABC subunit A
F CMR15_mp20075 uvrA; Excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F CMR15_20126 uvrB; ATP-dependent DNA excision repair enzyme, DNA damage recognition component K03702 uvrB; excinuclease ABC subunit B
F CMR15_mp10308 Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
F CMR15_mp20203 Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
F CMR15_mp20140 conserved hypothethical protein K03746 hns; DNA-binding protein H-NS
F CMR15_mp10030 Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
F CMR15_30020 Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CMR15_11585 dinB; DNA polymerase IV, devoid of proofreading, damage-inducible protein P K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D CMR15_30349 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
D CMR15_20512 lexA; transcriptional lexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D CMR15_10761 recN; DNA repair protein recN (Recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N)
D CMR15_mp10764 imuA; DNA damage-inducible mutagenesis protein K14160 imuA; protein ImuA
D CMR15_mp10765 imuB; required for the error-prone processing of DNA lesions along with dnaE2 and imuA K14161 imuB; protein ImuB
D CMR15_mp10766 dnaE; DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D CMR15_30484 ssb; ssDNA-binding protein, controls activity of RecBCD nuclease K03111 ssb; single-strand DNA-binding protein
D CMR15_30348 recX; recombination regulator RecX (Modulates recA activity) K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D CMR15_10177 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D CMR15_11628 putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D CMR15_10584 mutT; Mutator mutT protein (7, 8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CMR15_mp20067 putative thiamine-phosphate pyrophosphorylase (thiE) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CMR15_10914 dut; deoxyuridinetriphosphatase (dUTP diphosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CMR15_10610 nrdA; Ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CMR15_10611 nrdB; ribonucleoside diphosphate reductase 1, beta subunit, ferritin-like K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024