+F Repair protein KO
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DNA Repair and Recombination Proteins - Ralstonia solanacearum Po82
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D RSPO_c00947 methylated-dna--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RSPO_c00908 ogt; methylated-DNA-[protein]-cysteine s-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RSPO_c02697 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E RSPO_c00621 ung; uracil-dna glycosylase (udg) protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E RSPO_c03004 mutY; a/g-specific adenine glycosylase protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E RSPO_c02365 nth; endonuclease III protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D RSPO_c00677 mutT; mutator mutt protein (7, 8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RSPO_m01532 thiE2; thiamine-phosphate pyrophosphorylase protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RSPO_c00982 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase (dutpase) (dutp pyrophosphatase) protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D RSPO_c00947 methylated-dna--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RSPO_c00908 ogt; methylated-DNA-[protein]-cysteine s-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RSPO_c00882 adaptative response regulator AdA K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D RSPO_c02697 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D RSPO_c00884 alkB; alpha-ketoglutarate-dependent dioxygenase alkb K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E RSPO_c00621 ung; uracil-dna glycosylase (udg) protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E RSPO_c01988 uracil-DNA glycosylase,phage-like protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E RSPO_c02203 DNA-3-methyladenine glycosylase protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E RSPO_c00883 alkA; dna-3-methyladenine glycosylase protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E RSPO_c00949 ada; bifunctional methylated-DNA--protein-cysteine methyltransferase/O-6-methylguanine-DNA transcription regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E RSPO_c03004 mutY; a/g-specific adenine glycosylase protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E RSPO_m01003 tag; DNA-3-methyladenine glycosylase I protein K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E RSPO_c03006 mutM; formamidopyrimidine-dna glycosylase protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E RSPO_c02365 nth; endonuclease III protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E RSPO_c03224 exodeoxyribonuclease III protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E RSPO_c01670 xthA; exodeoxyribonuclease III protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E RSPO_c02257 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E RSPO_c01956 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E RSPO_c01200 polA; dna polymeraseIprotein K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E RSPO_c02981 uvrA1; excinuclease abc subunit a (dna repair atp-binding protein) K03701 uvrA; excinuclease ABC subunit A
E RSPO_m01256 uvrA2; excinuclease abc subunit a (dna repair atp-binding protein) K03701 uvrA; excinuclease ABC subunit A
E RSPO_c02358 uvrB; uvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E RSPO_c02295 uvrC; excinuclease abc subunit c (sos response dna repair protein) K03703 uvrC; excinuclease ABC subunit C
E RSPO_c01195 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E RSPO_m00719 uvrD; DNA helicase II protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E RSPO_c01200 polA; dna polymeraseIprotein K02335 polA; DNA polymerase I [EC:2.7.7.7]
E RSPO_c01956 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F RSPO_c00461 rpoB; RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F RSPO_c00462 rpoC; RNA polymerase, beta prime subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F RSPO_c00503 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F RSPO_c01300 rpoZ; rna polymerase omega subunit protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F RSPO_c01726 mfd; transcription-repair ATP-dependent coupling factor, helicase K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E RSPO_c02220 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E RSPO_c00888 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E RSPO_c00357 sbcB; exodeoxyribonucleaseIprotein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E RSPO_c00924 xseA; exonuclease vII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E RSPO_c01207 xseB; exodeoxyribonuclease vII small subunit (exonuclease vII small subunit) protein K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E RSPO_c01227 dnaE1; dna polymerase III (alpha chain) protein K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E RSPO_c00002 dnaN; dna polymerase III (beta chain) protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E RSPO_c01037 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E RSPO_c00758 holA; dna polymerase III (delta subunit) protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E RSPO_c01817 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E RSPO_c01518 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E RSPO_c02177 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E RSPO_c01956 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E RSPO_c01195 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E RSPO_m00719 uvrD; DNA helicase II protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E RSPO_c02979 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E RSPO_c02829 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
E RSPO_c02889 ruvA; holliday junction dna helicase ruva protein K03550 ruvA; holliday junction DNA helicase RuvA
E RSPO_c02890 ruvB; holliday junction dna helicase ruvb protein K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E RSPO_c02887 ruvC; endodeoxyribonuclease subunit C of ruvABC holliday junction resolvasome K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E RSPO_c00144 priA; primosome factor n' (replication factor y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E RSPO_c02049 priB; primosomal replication protein n K02686 priB; primosomal replication protein N
E RSPO_c00357 sbcB; exodeoxyribonucleaseIprotein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E RSPO_c02829 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
E RSPO_c01984 radA; atp-dependent protease, dna repair (atp-binding dna-binding) protein (sms protein) K04485 radA; DNA repair protein RadA/Sms
E RSPO_c00792 recG; atp-dependent dna helicase protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E RSPO_c02257 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E RSPO_c02301 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E RSPO_c02174 recR; recombination protein RecR K06187 recR; recombination protein RecR
E RSPO_c00850 recN; DNA repair protein recn (recombination protein n) K03631 recN; DNA repair protein RecN (Recombination protein N)
E RSPO_c02734 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E RSPO_c02889 ruvA; holliday junction dna helicase ruva protein K03550 ruvA; holliday junction DNA helicase RuvA
E RSPO_c02890 ruvB; holliday junction dna helicase ruvb protein K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E RSPO_c02887 ruvC; endodeoxyribonuclease subunit C of ruvABC holliday junction resolvasome K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E RSPO_c02179 addA; recombinational repair-like protein, atp-dependent exodnase (exonuclease v) beta subunit K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E RSPO_c01089 conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E RSPO_c01245 predicted atpase protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F RSPO_c02458 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F RSPO_c00003 gyrB; dna gyrase (subunit b) protein K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F RSPO_c00081 dbhB; histone-like dna-binding protein hu-beta (ns1) K03530 hupB; DNA-binding protein HU-beta
F RSPO_c00930 hupB2; dna-binding protein hu-beta (ns1) (hu-1) K03530 hupB; DNA-binding protein HU-beta
F RSPO_c01750 hupB1; dna-binding protein hu-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F RSPO_c02257 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F RSPO_c02301 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F RSPO_c02174 recR; recombination protein RecR K06187 recR; recombination protein RecR
F RSPO_c01956 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F RSPO_c01657 ihfA; integration host factor alpha-subunit (ihf-alpha) protein K04764 ihfA; integration host factor subunit alpha
F RSPO_c02448 ihfB; integration host factor beta-subunit (ihf-beta) protein K05788 ihfB; integration host factor subunit beta
E Supressor
F RSPO_c00357 sbcB; exodeoxyribonucleaseIprotein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F RSPO_c00470 recQ; atp-dependent dna helicase protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F RSPO_c02981 uvrA1; excinuclease abc subunit a (dna repair atp-binding protein) K03701 uvrA; excinuclease ABC subunit A
F RSPO_m01256 uvrA2; excinuclease abc subunit a (dna repair atp-binding protein) K03701 uvrA; excinuclease ABC subunit A
F RSPO_c02358 uvrB; uvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
F RSPO_c00259 hns; Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
F RSPO_m00039 hns; hns-like protein K03746 hns; DNA-binding protein H-NS
F RSPO_m00895 hns-like protein K03746 hns; DNA-binding protein H-NS
F RSPO_m01484 hns-like protein K03746 hns; DNA-binding protein H-NS
F RSPO_m01341 conserved hypothetical protein K03746 hns; DNA-binding protein H-NS
F RSPO_c02494 Histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D RSPO_c01663 dinB; DNA polymerase iv, devoid of proofreading, damage-inducible protein p K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D RSPO_c02829 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
D RSPO_c02054 lexA; lexa repressor protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D RSPO_c00850 recN; DNA repair protein recn (recombination protein n) K03631 recN; DNA repair protein RecN (Recombination protein N)
D RSPO_m01103 sulA; cell division inhibitor protein K14160 imuA; protein ImuA
D RSPO_m01105 dinP; dna polymerase iv protein K14161 imuB; protein ImuB
D RSPO_m01106 dnaE2; dna polymerase III (alpha chain) protein K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D RSPO_c02979 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D RSPO_c02828 recX; recombinase X K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D RSPO_c00165 rep; atp-dependent dna helicase rep protein K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D RSPO_c01705 dinG; atp-dependent dna helicase-related protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D RSPO_c00677 mutT; mutator mutt protein (7, 8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RSPO_m01532 thiE2; thiamine-phosphate pyrophosphorylase protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RSPO_c00982 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase (dutpase) (dutp pyrophosphatase) protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D RSPO_c00703 nrdA; ribonucleoside reductase 1 (large chain) protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D RSPO_c00704 nrdB; transmembrane ribonucleoside reductase (small chain) protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024