+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Ruminococcus torques</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    RTO_30930 type I site-specific deoxyribonuclease, HsdR family	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    RTO_30880 Restriction endonuclease S subunits	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    RTO_30870 Type I restriction-modification system methyltransferase subunit	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      RTO_31440 DNA modification methylase	K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] 
D      RTO_14860 DNA-methyltransferase (dcm)	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      RTO_32080 DNA-methyltransferase (dcm)	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
C    RTO_31450 Type III restriction enzyme, res subunit.	K01156 res; type III restriction enzyme [EC:3.1.21.5] 
B  Type IV R-M system
C    RTO_18410 HNH endonuclease.	K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] 
C    RTO_32090 hypothetical protein	K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-] 
C    RTO_30940 Restriction endonuclease	K07448 mrr; restriction system protein 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      RTO_12930 Growth inhibitor	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      RTO_19190 Growth inhibitor	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      RTO_31180 Growth inhibitor	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      RTO_19200 Growth regulator	K07172 mazE; antitoxin MazE 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
D      RTO_11910 addiction module toxin, RelE/StbE family	K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-] 
D      RTO_12180 addiction module toxin, RelE/StbE family	K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-] 
D      RTO_02950 addiction module antitoxin, RelB/DinJ family	K07473 dinJ; DNA-damage-inducible protein J 
D      RTO_11920 addiction module antitoxin, RelB/DinJ family	K07473 dinJ; DNA-damage-inducible protein J 
D      RTO_12170 addiction module antitoxin, RelB/DinJ family	K07473 dinJ; DNA-damage-inducible protein J 
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    SpoIISA-SpoIISB
C    Tse6-Tsi6
C    Type II TA system related factors
D      RTO_16440 rod shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      RTO_21480 Actin-like ATPase involved in cell morphogenesis	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      RTO_17240 glutamyl-tRNA synthetase, bacterial family	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
C    AbiEii-AbiEi
B  Type V TA system
C    GhoT-GhoS
C    Other GhoT/OrtT toxin family protein
B  Type VI TA system
C    SocB-SocA
B  Type VII TA system
C    Hha-TomB
C    TglT-TakA
C    HepT-MntA
B  Type VIII TA system
C    SdsR-RyeA
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    RTO_15520 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    RTO_17400 cysteine desulfurase NifS	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: May 19, 2025