+F Repair protein KO
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DNA Repair and Recombination Proteins - Ruminococcus sp. SR1/5
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CK1_37280 O-6-methylguanine DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CK1_34100 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CK1_15720 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CK1_15790 Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D CK1_11230 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CK1_34320 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CK1_18870 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CK1_37280 O-6-methylguanine DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CK1_34100 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CK1_15790 Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CK1_18890 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E CK1_11670 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E CK1_31700 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E CK1_05510 pseudouridine synthase family K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CK1_39420 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E CK1_20350 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
E CK1_22210 Superfamily I DNA and RNA helicases K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CK1_31700 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E CK1_05510 pseudouridine synthase family K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F CK1_25000 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F CK1_24990 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F CK1_11380 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CK1_10490 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E CK1_00840 MutS2 family protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E CK1_01930 exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E CK1_01940 Exonuclease VII small subunit. K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E CK1_00520 DNA polymerase III catalytic subunit, PolC type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E CK1_28210 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CK1_39520 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E CK1_28540 hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E CK1_17210 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E CK1_31700 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E CK1_05510 pseudouridine synthase family K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E CK1_22210 Superfamily I DNA and RNA helicases K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CK1_10160 single stranded DNA-binding protein (ssb) K03111 ssb; single-strand DNA-binding protein
E CK1_30150 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E CK1_36390 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E CK1_03130 single stranded DNA-binding protein (ssb) K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E CK1_10200 ATP-dependent exoDNAse (exonuclease V), alpha subunit-helicase superfamily I member K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CK1_26900 helicase, putative, RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CK1_39390 helicase, putative, RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CK1_33750 protein RecA K03553 recA; recombination protein RecA
E CK1_07480 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E CK1_07490 Holliday junction DNA helicase, RuvB subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CK1_22750 replication restart DNA helicase PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E CK1_20490 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E CK1_33750 protein RecA K03553 recA; recombination protein RecA
E CK1_20190 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E CK1_07690 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CK1_18950 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E CK1_17230 recombination protein RecR K06187 recR; recombination protein RecR
E CK1_02010 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E CK1_07880 Penicillin-binding protein-related factor A, putative recombinase K03700 recU; recombination protein U
E CK1_14250 Penicillin-binding protein-related factor A, putative recombinase K03700 recU; recombination protein U
E CK1_07480 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E CK1_07490 Holliday junction DNA helicase, RuvB subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E CK1_36670 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E CK1_36690 ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E CK1_25940 CRISPR-associated protein, Cas1 family K15342 cas1; CRISP-associated protein Cas1
E CK1_18710 CRISPR-associated protein, Cas1 family K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E CK1_20490 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F CK1_18570 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CK1_28590 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CK1_18560 DNA topoisomerase IV subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F CK1_28580 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F CK1_00620 Topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F CK1_35520 Bacterial nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F CK1_14080 RecT family. K07455 recT; recombination protein RecT
F CK1_18950 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F CK1_17230 recombination protein RecR K06187 recR; recombination protein RecR
F CK1_31700 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F CK1_05510 pseudouridine synthase family K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F CK1_20540 ATP-dependent DNA helicase, RecQ-like K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F CK1_39420 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CK1_10730 Nucleotidyltransferase/DNA polymerase involved in DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D CK1_27020 Nucleotidyltransferase/DNA polymerase involved in DNA repair K03502 umuC; DNA polymerase V
C Other SOS response factors
D CK1_33750 protein RecA K03553 recA; recombination protein RecA
D CK1_11080 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D CK1_02010 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D CK1_10160 single stranded DNA-binding protein (ssb) K03111 ssb; single-strand DNA-binding protein
D CK1_30150 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D CK1_36390 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D CK1_03130 single stranded DNA-binding protein (ssb) K03111 ssb; single-strand DNA-binding protein
D CK1_33760 Uncharacterized protein conserved in bacteria K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D CK1_11230 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CK1_34320 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CK1_18870 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024