+F	Repair protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Rhagoletis zephyria (snowberry fruit fly)</h2>
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A<b>Eukaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      108354015 methylated-DNA--protein-cysteine methyltransferase-like	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
D      108377738 activating signal cointegrator 1 complex subunit 3-like	K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] 
D      108361834 activating signal cointegrator 1 complex subunit 3	K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] 
D      108357897 deoxyribodipyrimidine photo-lyase-like	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
D      108357905 deoxyribodipyrimidine photo-lyase-like	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        108370414 uracil-DNA glycosylase-like	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        108364900 single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        108368089 N-glycosylase/DNA lyase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] 
E        108357950 endonuclease III-like protein 1 isoform X1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
E        108375931 recombination repair protein 1 isoform X1	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
E        108378106 DNA-(apurinic or apyrimidinic site) lyase-like	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
D      Long Patch-BER factors
E        DNA polymerase delta complex
F          108370702 DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
E        DNA polymerase epsilon complex
F          108366321 DNA polymerase epsilon catalytic subunit A isoform X1	K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] 
F          108365984 DNA polymerase epsilon subunit 2	K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 
F          108373200 DNA polymerase epsilon subunit 3	K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] 
F          108359320 DNA polymerase epsilon subunit 4	K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] 
E        108379337 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        108362683 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        108358285 flap endonuclease 1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] 
E        108383079 DNA ligase 1-like	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
D      Short Patch-BER factors
E        108372435 DNA ligase 3 isoform X1	K10776 LIG3; DNA ligase 3 [EC:6.5.1.1] 
D      Other BER factors
E        108371522 probable tyrosyl-DNA phosphodiesterase	K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] 
E        108362914 uncharacterized protein F21D5.5	K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
E        108366815 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        108377269 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        108375438 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        108362246 poly [ADP-ribose] polymerase isoform X1	K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        XPC-HR23B-CETN2 complex
F          108379690 DNA repair protein complementing XP-C cells homolog	K10838 XPC; xeroderma pigmentosum group C-complementing protein 
F          108378675 UV excision repair protein RAD23 homolog B-like	K10839 RAD23; UV excision repair protein RAD23 
F          108362657 UV excision repair protein RAD23 homolog B-like	K10839 RAD23; UV excision repair protein RAD23 
F          108364637 UV excision repair protein RAD23 homolog B-like	K10839 RAD23; UV excision repair protein RAD23 
F          108373309 centrin-2-like	K10840 CETN2; centrin-2 
E        Cul4-DDB2 complex
F          108377436 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108368697 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108368698 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108382225 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108381253 cullin-4A-like	K10609 CUL4; cullin 4 
F          108372663 cullin-4B-like	K10609 CUL4; cullin 4 
F          108358531 cullin-4A	K10609 CUL4; cullin 4 
F          108362985 DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
E        NER4 complex
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase II complex
F          108371873 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          108373899 DNA-directed RNA polymerase II subunit RPB1-like	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          108355351 DNA-directed RNA polymerase II subunit RPB1-like	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          108376425 DNA-directed RNA polymerase II subunit RPB2-like	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          108355452 DNA-directed RNA polymerase II subunit RPB2	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          108372160 DNA-directed RNA polymerase II subunit RPB3	K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 
F          108368669 DNA-directed RNA polymerase II 16 kDa polypeptide-like isoform X1	K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 
F          108381099 DNA-directed RNA polymerase II 16 kDa polypeptide	K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 
F          108381100 LOW QUALITY PROTEIN: transcriptional adapter 2A	K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 
F          108360991 DNA-directed RNA polymerases I, II, and III subunit RPABC1	K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 
F          108368223 DNA-directed RNA polymerases I, II, and III subunit RPABC2	K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 
F          108375303 DNA-directed RNA polymerases I, II, and III subunit RPABC2-like	K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 
F          108382691 DNA-directed RNA polymerase II subunit RPB7-like	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          108365491 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          108367069 DNA-directed RNA polymerases I, II, and III subunit RPABC3-like	K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 
F          108368633 DNA-directed RNA polymerase II subunit RPB9	K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 
F          108365121 DNA-directed RNA polymerase II subunit RPB9-like	K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 
F          108376901 DNA-directed RNA polymerases I, II, and III subunit RPABC5-like	K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 
F          108363420 DNA-directed RNA polymerases I, II, and III subunit RPABC5	K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 
F          108365052 DNA-directed RNA polymerase II subunit RPB11 isoform X1	K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 
F          108364771 DNA-directed RNA polymerases I, II, and III subunit RPABC4	K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 
E        Cul4-CSA complex
F          108377436 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108368697 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108368698 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108382225 RING-box protein 1A-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          108381253 cullin-4A-like	K10609 CUL4; cullin 4 
F          108372663 cullin-4B-like	K10609 CUL4; cullin 4 
F          108358531 cullin-4A	K10609 CUL4; cullin 4 
F          108362985 DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
E        Other TCR factor
F          108376741 transcription elongation factor 1 homolog	K25829 ELOF1; transcription elongation factor 1 
F          108380092 transcription elongation factor 1 homolog	K25829 ELOF1; transcription elongation factor 1 
F          108371861 uncharacterized protein LOC108371861	K25829 ELOF1; transcription elongation factor 1 
D      TFIIH complex
E        108366187 DNA excision repair protein haywire isoform X1	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] 
E        108355982 TFIIH basal transcription factor complex helicase XPB subunit-like	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] 
E        108377387 TFIIH basal transcription factor complex helicase XPD subunit-like	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        108382282 TFIIH basal transcription factor complex helicase XPD subunit-like	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        108363868 general transcription factor IIH subunit 1 isoform X1	K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 
E        108367487 general transcription factor IIH subunit 2	K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 
E        108374846 general transcription factor IIH subunit 2-like	K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 
E        108359041 general transcription factor IIH subunit 3 isoform X1	K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 
E        108366342 general transcription factor IIH subunit 4 isoform X1	K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 
E        108380384 general transcription factor IIH subunit 4-like	K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 
E        108380254 general transcription factor IIH subunit 5-like	K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit 
E        108375131 general transcription factor IIH subunit 5-like	K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit 
E        108368692 cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        108380029 cyclin-dependent kinase 7-like	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        108368190 cyclin-H-like	K06634 CCNH; cyclin H 
E        108377957 cyclin-H-like	K06634 CCNH; cyclin H 
E        108356206 cyclin-H-like	K06634 CCNH; cyclin H 
E        108358518 CDK-activating kinase assembly factor MAT1	K10842 MNAT1; CDK-activating kinase assembly factor MAT1 
D      RPA (replication factor A)
E        108373619 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        108381427 replication protein A 70 kDa DNA-binding subunit-like	K07466 RFA1; replication factor A1 
E        108365672 replication protein A 32 kDa subunit isoform X1	K10739 RFA2; replication factor A2 
E        108368783 uncharacterized protein LOC108368783	K10740 RPA3; replication factor A3 
D      Other NER factors
E        108381908 DNA repair protein complementing XP-A cells homolog	K10847 XPA; DNA-repair protein complementing XP-A cells 
E        108383199 DNA repair protein complementing XP-A cells homolog	K10847 XPA; DNA-repair protein complementing XP-A cells 
E        108362093 DNA excision repair protein ERCC-1	K10849 ERCC1; DNA excision repair protein ERCC-1 
E        108373682 DNA repair endonuclease XPF	K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] 
E        108358143 DNA repair protein complementing XP-G cells homolog	K10846 ERCC5; DNA excision repair protein ERCC-5 
E        108383079 DNA ligase 1-like	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
E        108381036 MMS19 nucleotide excision repair protein homolog isoform X1	K15075 MET18; DNA repair/transcription protein MET18/MMS19 
E        108361423 cullin-3 isoform X1	K03869 CUL3; cullin 3 
E        108373032 cullin-3-like	K03869 CUL3; cullin 3 
E        108364591 cullin-5 isoform X1	K10612 CUL5; cullin 5 
E        108379494 transcription elongation factor B polypeptide 1-like	K03872 ELOC; elongin-C 
E        108360493 transcription elongation factor B polypeptide 1	K03872 ELOC; elongin-C 
E        108373291 transcription elongation factor B polypeptide 2	K03873 ELOB; elongin-B 
E        108356966 transcription elongation factor B polypeptide 2-like	K03873 ELOB; elongin-B 
E        108381981 transcription elongation factor B polypeptide 3-like	K15076 ELOA; elongin-A 
E        108364905 transcription elongation factor B polypeptide 3 isoform X1	K15076 ELOA; elongin-A 
E        108363791 protein lingerer isoform X1	K26545 UBAP2; ubiquitin-associated protein 2 
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
E        108367107 DNA mismatch repair protein spellchecker 1 isoform X1	K08735 MSH2; DNA mismatch repair protein MSH2 
E        108376499 LOW QUALITY PROTEIN: probable DNA mismatch repair protein Msh6	K08737 MSH6; DNA mismatch repair protein MSH6 
D      MutL homologs
E        108379766 DNA mismatch repair protein Mlh1 isoform X1	K08734 MLH1; DNA mismatch repair protein MLH1 
E        108363924 mismatch repair endonuclease PMS2 isoform X1	K10858 PMS2; DNA mismatch repair protein PMS2 
D      DNA polymerase delta complex
E        108370702 DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
D      RPA (replication factor A)
E        108373619 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        108381427 replication protein A 70 kDa DNA-binding subunit-like	K07466 RFA1; replication factor A1 
E        108365672 replication protein A 32 kDa subunit isoform X1	K10739 RFA2; replication factor A2 
E        108368783 uncharacterized protein LOC108368783	K10740 RPA3; replication factor A3 
D      RFC (replication factor C)
E        108373112 replication factor C subunit 1	K10754 RFC1; replication factor C subunit 1 
E        108377455 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
E        108360540 replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
E        108356570 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
E        108358559 replication factor C subunit 2-like	K10755 RFC2_4; replication factor C subunit 2/4 
E        108367120 replication factor C subunit 5-like	K10756 RFC3_5; replication factor C subunit 3/5 
E        108369645 replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
E        108374994 replication factor C subunit 5-like	K10756 RFC3_5; replication factor C subunit 3/5 
D      Other MMR factors
E        108379337 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
E        108362683 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        108365782 exonuclease 1 isoform X1	K10746 EXO1; exonuclease 1 [EC:3.1.-.-] 
E        108366815 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        108377269 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        108375438 high mobility group protein DSP1-like	K10802 HMGB1; high mobility group protein B1 
E        108383079 DNA ligase 1-like	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      MRN(MRX) complex
E        108375868 double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        108359028 DNA repair protein RAD50 isoform X1	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA1-core complex
D      BRCA1-A complex
D      BRCA1-B complex
E        108378843 DNA topoisomerase 2-binding protein 1-A	K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 
D      BRCA1-C complex
E        108375868 double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        108359028 DNA repair protein RAD50 isoform X1	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA complex
E        108379236 DNA repair protein RAD51 homolog 1 isoform X1	K04482 RAD51; DNA repair protein RAD51 
E        108372878 DNA repair protein RAD51 homolog A-like	K04482 RAD51; DNA repair protein RAD51 
D      RecA family proteins
E        108379236 DNA repair protein RAD51 homolog 1 isoform X1	K04482 RAD51; DNA repair protein RAD51 
E        108372878 DNA repair protein RAD51 homolog A-like	K04482 RAD51; DNA repair protein RAD51 
D      Rad52 family proteins
D      Rad54 family proteins
E        108381774 DNA repair and recombination protein RAD54-like	K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] 
E        108364474 DNA repair and recombination protein RAD54-like	K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] 
E        108359281 helicase ARIP4 isoform X1	K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] 
D      RecQ family DNA helicases
E        108369305 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        108375802 Bloom syndrome protein-like	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        108380735 LOW QUALITY PROTEIN: uncharacterized protein LOC108380735	K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4] 
E        108375294 ATP-dependent DNA helicase Q5-like	K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4] 
D      Bloom's syndrome complex (BTR)
E        108369305 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        108375802 Bloom syndrome protein-like	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        108360599 DNA topoisomerase 3-alpha	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        108380593 DNA topoisomerase 3-alpha-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        108365578 DNA topoisomerase 3-beta	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        108375821 DNA topoisomerase 3-beta-1-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
D      RPA (replication factor A)
E        108373619 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        108381427 replication protein A 70 kDa DNA-binding subunit-like	K07466 RFA1; replication factor A1 
E        108365672 replication protein A 32 kDa subunit isoform X1	K10739 RFA2; replication factor A2 
E        108368783 uncharacterized protein LOC108368783	K10740 RPA3; replication factor A3 
D      Protein phosphatase 4
E        108360859 serine/threonine-protein phosphatase 4 catalytic subunit	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        108373749 serine/threonine-protein phosphatase 4 catalytic subunit-like	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        108363268 serine/threonine-protein phosphatase 4 regulatory subunit 3-like isoform X1	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
D      AP-5 complex
D      SMC5-SMC6 complex
E        108373114 structural maintenance of chromosomes protein 5	K22803 SMC5; structural maintenance of chromosomes protein 5 
E        108371035 non-structural maintenance of chromosomes element 1 homolog	K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] 
E        108376349 EP300-interacting inhibitor of differentiation 3	K22825 NSMCE4; non-structural maintenance of chromosomes element 4 
D      Other HR factors
E        108364365 crossover junction endonuclease EME1	K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] 
E        108372674 exonuclease 3'-5' domain-containing protein 2 isoform X1	K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] 
E        108355244 crossover junction endonuclease MUS81	K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] 
E        108356631 structure-specific endonuclease subunit SLX1 homolog	K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] 
E        108363109 flap endonuclease GEN	K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] 
E        108374563 uncharacterized protein LOC108374563 isoform X1	K19026 SPG11; spatacsin 
E        108365968 LOW QUALITY PROTEIN: nuA4 complex subunit EAF3 homolog	K11339 MORF4L1; mortality factor 4-like protein 1 
E        108379386 mortality factor 4-like protein 1	K11339 MORF4L1; mortality factor 4-like protein 1 
E        108354176 nuA4 complex subunit EAF3 homolog	K11339 MORF4L1; mortality factor 4-like protein 1 
E        108360321 fidgetin-like protein 1	K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] 
E        108379584 uncharacterized protein LOC108379584	K23112 BRAT1; BRCA1-associated ATM activator 1 
E        108368382 mediator of RNA polymerase II transcription subunit 15-like isoform X1	K23456 CFAP410; cilla- and flagella-associated protein 
E        108372681 adenylate cyclase, terminal-differentiation specific-like isoform X1	K23456 CFAP410; cilla- and flagella-associated protein 
E        108370062 protein MMS22-like	K26125 MMS22L; protein MMS22-like 
E        108363105 tonsoku-like protein isoform X1	K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 
E        108379168 Werner Syndrome-like exonuclease	K22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-] 
C    NHEJ (non-homologous end-joining)
D      DNA-PK complex
E        108359372 ATP-dependent DNA helicase 2 subunit 1	K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 
E        108359468 X-ray repair cross-complementing protein 5	K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 
D      MRX complex
E        108375868 double-strand break repair protein MRE11-like	K10865 MRE11; double-strand break repair protein MRE11 
E        108359028 DNA repair protein RAD50 isoform X1	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      DNA Ligase 4 complex
E        108361997 DNA ligase 4	K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] 
D      X-family DNA polymerases
D      Other NHEJ factors
C    FA (Fanconi anemia) pathway
D      FA core complex
E        108370599 E3 ubiquitin-protein ligase FANCL	K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] 
E        108363100 uncharacterized protein LOC108363100 isoform X1	K10896 FANCM; fanconi anemia group M protein 
D      FA core complex binding factors
E        108355229 transcription factor HES-1-like	K06054 HES1; hairy and enhancer of split 1 
E        108369345 ubiquitin-conjugating enzyme E2 2-like	K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] 
D      Bloom's syndrome complex (BTR)
E        108369305 Bloom syndrome protein homolog	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        108375802 Bloom syndrome protein-like	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        108360599 DNA topoisomerase 3-alpha	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        108380593 DNA topoisomerase 3-alpha-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        108365578 DNA topoisomerase 3-beta	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        108375821 DNA topoisomerase 3-beta-1-like	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
D      FANCD2-I complex
E        108362531 Fanconi anemia group D2 protein isoform X1	K10891 FANCD2; fanconi anemia group D2 protein 
E        108360076 Fanconi anemia group I protein homolog	K10895 FANCI; fanconi anemia group I protein 
D      Downstream FA components
D      Other FA pathway factors
E        108379236 DNA repair protein RAD51 homolog 1 isoform X1	K04482 RAD51; DNA repair protein RAD51 
E        108372878 DNA repair protein RAD51 homolog A-like	K04482 RAD51; DNA repair protein RAD51 
E        108371490 uncharacterized protein LOC108371490	K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] 
E        108379041 WD repeat-containing protein 48	K15361 WDR48; WD repeat-containing protein 48 
C    Other DSBR factors
D      Protein phosphatase 6
E        108369736 serine/threonine-protein phosphatase 6 catalytic subunit-like	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
E        108358055 serine/threonine-protein phosphatase 6 catalytic subunit	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
D      Ubiquitin ligases
E        108358654 probable E3 ubiquitin-protein ligase HERC2	K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
D      Others
E        108371116 telomerase Cajal body protein 1	K23314 WRAP53; telomerase Cajal body protein 1 
E        108360578 gastrulation defective protein 1 homolog	K24752 WDR70; WD repeat-containing protein 70 
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
D      108375825 DNA polymerase eta	K03509 POLH; DNA polymerase eta [EC:2.7.7.7] 
D      108374635 DNA polymerase iota isoform X1	K03510 POLI; DNA polymerase iota [EC:2.7.7.7] 
D      108372793 DNA repair protein REV1	K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] 
C    B-family DNA polymerases
D      108370160 DNA polymerase zeta catalytic subunit-like	K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] 
D      108370161 DNA polymerase zeta catalytic subunit	K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] 
C    A-family DNA polymerase
C    Rad6 epistasis group
D      108363351 ubiquitin-conjugating enzyme E2-17 kDa	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      108373470 ubiquitin-conjugating enzyme E2 B-like	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      108375424 ubiquitin-conjugating enzyme E2 A	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      108368373 ubiquitin-conjugating enzyme E2 variant 2	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      108364074 ubiquitin-conjugating enzyme E2 N	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      108354125 ubiquitin-conjugating enzyme E2 N	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
C    Other TLS factors
D      108379337 proliferating cell nuclear antigen-like	K04802 PCNA; proliferating cell nuclear antigen 
D      108362683 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
D      108358503 sprT-like domain-containing protein Spartan	K24051 SPRTN; SprT-like domain-contaning protein Spartan 
D      108374879 uncharacterized protein LOC108374879 isoform X1	K26957 GCNA; germ cell nuclear acidic protein 
B  Check point factors
C    Rad9-Hus1-Rad1 complex
D      108375148 checkpoint protein HUS1	K10903 HUS1; HUS1 checkpoint protein 
D      108382730 cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    HRAD17(Rad24)-RFC complex
D      108362507 cell cycle checkpoint protein RAD17 isoform X1	K06662 HRAD17; cell cycle checkpoint protein 
D      108377455 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
D      108360540 replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
D      108356570 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
D      108358559 replication factor C subunit 2-like	K10755 RFC2_4; replication factor C subunit 2/4 
D      108367120 replication factor C subunit 5-like	K10756 RFC3_5; replication factor C subunit 3/5 
D      108369645 replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
D      108374994 replication factor C subunit 5-like	K10756 RFC3_5; replication factor C subunit 3/5 
C    Rad17-Mec3-Ddc1 complex
D      108382730 cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    FPC (fork protection complex)
D      108380856 protein timeless homolog	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      108365666 protein timeless homolog	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      108365781 protein TIPIN homolog	K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 
C    Triple T complex
D      108362916 uncharacterized protein LOC108362916	K20403 TTI1; TELO2-interacting protein 1 
C    BAG6-UBL4A-GET4 complex
D      108369208 ubiquitin-like protein 4A	K23388 UBL4; ubiquitin-like protein 4 
D      108367389 Golgi to ER traffic protein 4 homolog	K23387 GET4; golgi to ER traffic protein 4 
C    Other check point factors
D      108359200 serine/threonine-protein kinase ATR isoform X1	K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] 
D      108366977 serine/threonine-protein kinase ATM isoform X1	K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] 
D      108367897 serine/threonine-protein kinase Chk1-like	K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] 
D      108374399 serine/threonine-protein kinase grp-like	K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] 
D      108366280 ovarian-specific serine/threonine-protein kinase Lok isoform X1	K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
D      108364629 M-phase inducer phosphatase	K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] 
D      108368450 14-3-3 protein zeta	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      108371192 14-3-3 protein zeta	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      108362935 14-3-3 protein epsilon	K06630 YWHAE; 14-3-3 protein epsilon 
D      108367519 protein sickie-like	K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] 
D      108363689 protein sickie	K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] 
D      108369274 wee1-like protein kinase	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      108368088 period circadian protein isoform X1	K02633 PER2; period circadian protein 2 
D      108375162 plastin-3 isoform X1	K17336 PLS3; plastin-3 
D      108375312 plastin-2-like	K17336 PLS3; plastin-3 
D      108368222 protein downstream neighbor of son homolog	K22422 DONSON; protein downstream neighbor of Son 
D      108360385 LOW QUALITY PROTEIN: uncharacterized protein LOC108360385	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      108376350 vacuolar protein sorting-associated protein 4B	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      108378291 vacuolar protein sorting-associated protein 4B-like	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      108354433 LOW QUALITY PROTEIN: abscission/NoCut checkpoint regulator	K24778 ZFYVE19; abscission/NoCut checkpoint regulator 
D      108358707 protein SDE2 homolog	K25059 SDE2; replication stress response regulator SDE2 
B  Other factors with a suspected DNA repair function
C    DNA polymerases
D      108368079 LOW QUALITY PROTEIN: DNA polymerase theta-like	K02349 POLQ; DNA polymerase theta [EC:2.7.7.7] 
C    Nucleases
D      108367268 uncharacterized protein LOC108367268	K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] 
D      108379247 uncharacterized protein LOC108379247	K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1 
C    Helicases
D      108358866 helicase POLQ-like	K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] 
C    PSO4 complex
D      108359686 pre-mRNA-processing factor 19	K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] 
D      108360828 cell division cycle 5-like protein	K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 
D      108364901 pre-mRNA-splicing factor SPF27	K12861 BCAS2; pre-mRNA-splicing factor SPF27 
D      108374513 pleiotropic regulator 1	K12862 PLRG1; pleiotropic regulator 1 
C    Modulation of nucleotide pools
D      108369023 8-oxo-dGDP phosphatase NUDT18-like	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      108378534 8-oxo-dGDP phosphatase NUDT18-like	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      108363247 8-oxo-dGDP phosphatase NUDT18-like	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      108374419 deoxyuridine 5'-triphosphate nucleotidohydrolase-like	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      108366114 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      108378285 ribonucleoside-diphosphate reductase large subunit	K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 
D      108362267 ribonucleoside-diphosphate reductase subunit M2	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
#
A<b>Prokaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      108354015 methylated-DNA--protein-cysteine methyltransferase-like	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
D      108357897 deoxyribodipyrimidine photo-lyase-like	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
D      108357905 deoxyribodipyrimidine photo-lyase-like	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        108370414 uracil-DNA glycosylase-like	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        108364900 single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        108357950 endonuclease III-like protein 1 isoform X1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
D      RecJ
D      DNA ligase
D      DNA polymerase I
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase complex (RNAP)
E        TRCF (transcription-repair coupling factor)
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
D      Molecular matchmaker
D      Strand discrimination factor
D      DNA exonucleases
D      DNA polymerase III holoenzyme
D      DNA ligase
D      Other MMR factors
E        108361449 single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      RecBC pathway proteins
D      RecFOR pathway proteins
D      AddAB pathway proteins
D      Other HR factor
D      Archaeal homologous recombinant proteins
C    NHEJ (non-homologous end-joining)
D      Two-component NHEJ DNA repair complex
D      SHIIR (short-homology-independent illegitimate recombination)
E        Facilitator
F          108370723 DNA gyrase subunit A-like	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] 
E        Supressor
D      SHDIR (short-homology-dependent illegitimate recombination)
E        RecET pathway
E        Facilitator
E        Supressor
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
C    Other SOS response factors
D      108361449 single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  Other factors with a suspected DNA repair function
C    DNA polymerase
C    DNA helicases
C    Modulation of nucleotide pools
D      108374419 deoxyuridine 5'-triphosphate nucleotidohydrolase-like	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      108366114 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
C    Others
!
#<hr>
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#Last updated: March 29, 2024