+E Ubiquitin system KO
#
Ubiquitin System - Rhagoletis zephyria (snowberry fruit fly)
%
!
AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 108357389 polyubiquitin-B K04551 UBB; ubiquitin B
C 108358653 polyubiquitin-C K08770 UBC; ubiquitin C
C 108367178 ubiquitin-60S ribosomal protein L40-like K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 108381209 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 108382741 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 108359003 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 108365786 NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 108367466 uncharacterized protein LOC108367466 K02983 RP-S30e; small subunit ribosomal protein S30e
C 108367472 uncharacterized protein LOC108367472 K02983 RP-S30e; small subunit ribosomal protein S30e
C 108379818 ubiquitin-like protein FUBI K02983 RP-S30e; small subunit ribosomal protein S30e
C 108357585 uncharacterized protein LOC108357585 K02983 RP-S30e; small subunit ribosomal protein S30e
C 108377427 small ubiquitin-related modifier-like K12160 SUMO; small ubiquitin-related modifier
C 108375089 small ubiquitin-related modifier 3-like K12160 SUMO; small ubiquitin-related modifier
C 108354842 small ubiquitin-related modifier 3-like K12160 SUMO; small ubiquitin-related modifier
C 108380262 gamma-aminobutyric acid receptor-associated protein-like K08341 GABARAP; GABA(A) receptor-associated protein
C 108364758 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 108369268 autophagy protein 12-like K08336 ATG12; ubiquitin-like protein ATG12
C 108377191 ubiquitin-related modifier 1 homolog K12161 URM1; ubiquitin related modifier 1
C 108378895 ubiquitin-fold modifier 1-like K12162 UFM1; ubiquitin-fold modifier 1
C 108362144 ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
#
AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 108376171 ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
C 108360560 ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 108382018 SUMO-activating enzyme subunit 1-like K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 108362582 SUMO-activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 108358230 SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 108376183 NEDD8-activating enzyme E1 catalytic subunit-like K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 108363382 nedd8-activating enzyme E1 catalytic subunit K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 108359502 nedd8-activating enzyme E1 regulatory subunit K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 108371186 adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 108375579 adenylyltransferase and sulfurtransferase MOCS3-like K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 108374794 ubiquitin-like modifier-activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 108354572 ubiquitin-like modifier-activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 108376275 ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
#
AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 108363351 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 108373470 ubiquitin-conjugating enzyme E2 B-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 108375424 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 108369346 ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 108372488 probable ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 108369614 ubiquitin-conjugating enzyme E2-17 kDa K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 108381321 ubiquitin-conjugating enzyme E2-17 kDa-like K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 108382647 ubiquitin-conjugating enzyme E2-17 kDa-like K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 108372812 ubiquitin-conjugating enzyme E2 4-like K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 108370346 ubiquitin-conjugating enzyme E2 E1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 108380161 ubiquitin-conjugating enzyme E2 15-like K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 108364966 ubiquitin-conjugating enzyme E2 G1 isoform X1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 108374572 probable ubiquitin-conjugating enzyme E2 7 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 108367336 ubiquitin-conjugating enzyme E2 G2 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 108382890 ubiquitin-conjugating enzyme E2 G2-like K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 108370422 ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 108364220 ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 108355779 ubiquitin-conjugating enzyme E2 J2-like K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 108361759 ubiquitin-conjugating enzyme E2-22 kDa K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 108381108 ubiquitin-conjugating enzyme E2-22 kDa-like K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 108367786 ubiquitin-conjugating enzyme E2 L3-like K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 108374499 ubiquitin-conjugating enzyme E2 L3 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 108364074 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 108354125 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 108373579 (E3-independent) E2 ubiquitin-conjugating enzyme K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 108368357 ubiquitin-conjugating enzyme E2 Q2-like K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 108378033 ubiquitin-conjugating enzyme E2Q-like protein 1 isoform X1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 108379134 uncharacterized protein LOC108379134 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 108366340 ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 108377721 ubiquitin-conjugating enzyme E2 S-like K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 108374974 ubiquitin-conjugating enzyme E2 S-like K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 108365975 ubiquitin-conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 108369345 ubiquitin-conjugating enzyme E2 2-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 108382106 ubiquitin-conjugating enzyme E2 W-like K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 108358516 ubiquitin-conjugating enzyme E2 W isoform X1 K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 108354574 baculoviral IAP repeat-containing protein 6 isoform X1 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 108381029 SUMO-conjugating enzyme UBC9-like K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 108373068 SUMO-conjugating enzyme UBC9-like K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 108373623 SUMO-conjugating enzyme UBC9-B K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 108371466 NEDD8-conjugating enzyme UBE2F-like K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 108364119 nedd8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 108380997 ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 108374694 ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 108357913 ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 108376622 ubiquitin-fold modifier-conjugating enzyme 1-like K12165 UFC1; ufm1-conjugating enzyme 1
C 108372998 ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 108363731 ubiquitin-protein ligase E3A K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 108373307 ubiquitin-protein ligase E3B-like K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 108374240 ubiquitin-protein ligase E3B-like K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 108371806 ubiquitin-protein ligase E3C-like K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 108368249 ubiquitin-protein ligase E3C K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 108366817 E3 ubiquitin-protein ligase SMURF1-like K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 108363130 E3 ubiquitin-protein ligase Smurf1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 108366925 E3 ubiquitin-protein ligase Su(dx)-like K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 108374233 E3 ubiquitin-protein ligase Su(dx)-like K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 108369656 E3 ubiquitin-protein ligase TRIP12-like K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 108375026 E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 108360334 E3 ubiquitin-protein ligase Nedd-4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 108378600 E3 ubiquitin-protein ligase Nedd-4-like K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 108362310 E3 ubiquitin-protein ligase HUWE1 isoform X1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 108374627 E3 ubiquitin-protein ligase HUWE1-like K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 108376730 apoptosis-resistant E3 ubiquitin protein ligase 1-like K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 108359930 apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 108364061 E3 ubiquitin-protein ligase hyd isoform X1 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 108358654 probable E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 108360333 probable E3 ubiquitin-protein ligase HERC4 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 108358946 E3 ubiquitin-protein ligase HECW2 isoform X1 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 108374016 E3 ubiquitin-protein ligase HECTD1 isoform X1 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 108372032 NEDD4 family-interacting protein 1-like K25839 NDFIP; NEDD4 family-interacting protein
B U-box type E3
C 108358272 ubiquitin conjugation factor E4 A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 108369082 ubiquitin conjugation factor E4 B isoform X1 K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 108377720 E3 ubiquitin-protein ligase CHIP-like K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 108362435 E3 ubiquitin-protein ligase CHIP-like K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 108371926 peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 108357436 peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 108359686 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 108369464 RING finger protein 37 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 108376115 E3 ubiquitin-protein ligase Bre1-like K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
D 108371274 E3 ubiquitin-protein ligase Bre1-like K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 108376206 probable GPI-anchored adhesin-like protein PGA18 K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 108355018 E3 ubiquitin-protein ligase CBL-like K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 108374689 E3 ubiquitin-protein ligase sina K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 108373710 E3 ubiquitin-protein ligase SIAH1-like K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
C Ligand of Numb proteins
C March proteins
D 108358209 uncharacterized protein LOC108358209 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 108367395 E3 ubiquitin-protein ligase MARCH5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 108363474 E3 ubiquitin-protein ligase MARCH5-like K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 108374741 E3 ubiquitin-protein ligase MARCH6 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
D 108354865 E3 ubiquitin-protein ligase MARCH6-like K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D 108366497 protein shuttle craft K12236 NFX1; transcriptional repressor NF-X1
D 108361601 NF-X1-type zinc finger protein NFXL1 isoform X1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 108356265 protein pellino-like K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 108368521 peroxisome biogenesis factor 10-like K13346 PEX10; peroxin-10
D 108354541 peroxisome biogenesis factor 10-like K13346 PEX10; peroxin-10
D 108370435 peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 108369101 peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 108353944 E3 ubiquitin-protein ligase parkin K04556 PARK2; parkin [EC:2.3.2.31]
D 108372864 E3 ubiquitin-protein ligase ARIH1-like K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 108354450 protein ariadne-1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 108369024 protein ariadne-2-like K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 108353990 protein ariadne-2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 108364452 uncharacterized protein LOC108364452 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 108366198 cell wall protein DAN4 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
C TRAF proteins
D 108364599 TNF receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 108367176 brain tumor protein-like K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 108374020 brain tumor protein K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 108365884 E3 ubiquitin-protein ligase TRIM9-like K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 108373135 E3 ubiquitin-protein ligase TRIM33 isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 108366749 uncharacterized protein LOC108366749 isoform X1 K12021 TRIM45; tripartite motif-containing protein 45
D 108359592 protein wech K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 108363961 RING finger protein nhl-1 isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D 108376750 E3 ubiquitin-protein ligase UBR1 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 108370495 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR3-like K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 108373906 E3 ubiquitin-protein ligase UBR3-like K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 108359089 protein purity of essence K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 108379212 putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
D 108365048 putative E3 ubiquitin-protein ligase UBR7 isoform X1 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 108360652 death-associated inhibitor of apoptosis 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 108365060 death-associated inhibitor of apoptosis 1 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 108380651 BRCA1-associated protein isoform X1 K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 108354776 BRCA1-associated protein-like K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 108361341 uncharacterized protein LOC108361341 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 108366648 protein deltex K06058 DTX; deltex [EC:2.3.2.27]
D 108355361 protein deltex-like K06058 DTX; deltex [EC:2.3.2.27]
D 108370599 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 108366886 E3 ubiquitin-protein ligase KCMF1-like isoform X1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 108372676 E3 ubiquitin-protein ligase MIB2 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 108372779 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase mind-bomb-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 108374582 E3 ubiquitin-protein ligase MIB1-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 108361364 probable E3 ubiquitin-protein ligase makorin-1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 108365506 mitochondrial ubiquitin ligase activator of nfkb 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 108367695 E3 ubiquitin-protein ligase MYLIP isoform X1 K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 108378989 RING finger and CHY zinc finger domain-containing protein 1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 108373609 roquin-2 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 108369856 E3 ubiquitin-protein ligase RFWD3 isoform X1 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 108362401 E3 ubiquitin-protein ligase RING1 isoform X1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 108355459 E3 ubiquitin-protein ligase RING2-like K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 108357765 E3 ubiquitin-protein ligase RING1-like K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 108375750 E3 ubiquitin-protein ligase RNF185-like K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 108381536 E3 ubiquitin-protein ligase RNF185 isoform X1 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 108368520 RING finger protein 10 isoform X1 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 108372025 RING finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 108375575 RING finger protein 11-like K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 108371543 E3 ubiquitin-protein ligase RNF13 isoform X1 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 108355207 E3 ubiquitin-protein ligase RNF25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 108372735 E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 108377940 E3 ubiquitin-protein ligase NRDP1-like K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 108367579 E3 ubiquitin-protein ligase RNF126-B K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 108363287 RING finger protein 121 K15698 RNF121_175; RING finger protein 121/175
D 108354232 RING finger protein 121-like K15698 RNF121_175; RING finger protein 121/175
D 108359477 E3 ubiquitin-protein ligase RNF123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 108381261 LOW QUALITY PROTEIN: protein TRC8 homolog K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 108354195 protein TRC8 homolog K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 108369802 E3 ubiquitin-protein ligase RNF146 isoform X1 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 108382559 E3 ubiquitin-protein ligase MGRN1 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 108379123 E3 ubiquitin-protein ligase RNF181 homolog K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 108382104 E3 ubiquitin-protein ligase RNF181 homolog K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 108360892 E3 ubiquitin-protein ligase RNF220 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 108366249 U4/U6.U5 tri-snRNP-associated protein 1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 108376143 U4/U6.U5 tri-snRNP-associated protein 1-like K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 108383186 E3 ubiquitin-protein ligase SHPRH K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 108366580 E3 ubiquitin-protein ligase SH3RF1 isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 108376802 E3 ubiquitin-protein ligase synoviolin B-like K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 108364979 E3 ubiquitin-protein ligase HRD1 isoform X1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 108367392 E3 ubiquitin-protein ligase TM129 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 108362242 E3 ubiquitin-protein ligase TRAIP-like K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 108363544 E3 ubiquitin-protein ligase TRAIP-like K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 108365840 zinc finger protein 598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 108378313 E3 ubiquitin-protein ligase ZNRF2-like K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 108374550 uncharacterized protein LOC108374550 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
B Atypical E3
C 108371035 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 108371399 interferon regulatory factor 2-binding protein 2-A isoform X1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 108365716 E3 SUMO-protein ligase PIAS2 isoform X1 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 108379994 zinc finger BED domain-containing protein 1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 108359479 E3 UFM1-protein ligase 1 homolog isoform X1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 108359480 E3 UFM1-protein ligase 1 homolog isoform X1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 108377965 DCN1-like protein K17822 DCUN1D1_2; DCN1-like protein 1/2
C 108366237 DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 108369070 DCN1-like protein 5 isoform X1 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108379281 cullin homolog 1 K03347 CUL1; cullin 1
D Adaptor protein
E 108355214 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 108357450 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 108363492 beta-TrCP K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 108361126 F-box/WD repeat-containing protein 5 isoform X1 K10263 FBXW5; F-box and WD-40 domain protein 5
E 108359500 F-box/WD repeat-containing protein 7 isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 108374573 F-box/WD repeat-containing protein 7-like K10260 FBXW7; F-box and WD-40 domain protein 7
E 108365035 uncharacterized protein LOC108365035 isoform X1 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 108363060 F-box/LRR-repeat protein 20 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 108374260 F-box/LRR-repeat protein 20-like K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 108369385 F-box/LRR-repeat protein 4-like K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 108375394 F-box/LRR-repeat protein 4-like isoform X1 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 108363881 uncharacterized protein LOC108363881 isoform X1 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 108359490 F-box/LRR-repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 108363925 EIN3-binding F-box protein 2 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 108380816 jmjC domain-containing histone demethylation protein 1-like K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 108359288 F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 108373038 F-box/LRR-repeat protein 15 isoform X1 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 108377058 F-box/LRR-repeat protein 16-like K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 108363891 F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 108378266 LOW QUALITY PROTEIN: F-box only protein 9 K10295 FBXO9; F-box protein 9
E 108380629 F-box only protein 11-like K10297 FBXO11; F-box protein 11
E 108366052 F-box only protein 11 K10297 FBXO11; F-box protein 11
E 108368830 F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E 108358462 uncharacterized protein LOC108358462 K10306 FBXO28; F-box protein 28
E 108381793 uncharacterized protein LOC108381793 K10306 FBXO28; F-box protein 28
E 108373940 LOW QUALITY PROTEIN: F-box only protein 33 K10310 FBXO33; F-box protein 33
E 108376266 uncharacterized protein LOC108376266 K10314 FBXO39; F-box protein 39
E 108366655 uncharacterized protein LOC108366655 K10317 FBXO42; F-box protein 42
E 108379024 F-box/SPRY domain-containing protein 1-like K10319 FBXO45; F-box protein 45
E 108363840 F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
E 108354269 F-box/SPRY domain-containing protein 1-like K10319 FBXO45; F-box protein 45
C Cul2 complex
D Ring finger protein
E 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108364661 cullin-2 isoform X1 K03870 CUL2; cullin 2
D Adoptor protein
E 108379494 transcription elongation factor B polypeptide 1-like K03872 ELOC; elongin-C
E 108360493 transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 108373291 transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
E 108356966 transcription elongation factor B polypeptide 2-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 108369381 leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 108371481 protein fem-1 homolog CG6966-like K25805 FEM1A_C; protein fem-1 homolog A/C
E 108373094 protein fem-1 homolog CG6966-like K25805 FEM1A_C; protein fem-1 homolog A/C
E 108364893 protein fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 108371902 protein fem-1 homolog B isoform X1 K10349 FEM1B; protein fem-1 homolog B
E 108379255 amyloid protein-binding protein 2 isoform X1 K25806 APPBP2; amyloid protein-binding protein 2
E 108367344 kelch domain-containing protein 3 K25808 KLHDC3; kelch domain-containing protein 3
E 108366405 kelch domain-containing protein 10 homolog K25809 KLHDC10; kelch domain-containing protein 10
E 108365192 protein zer-1 homolog K10350 ZYG11; Zyg-11 protein
E 108363637 zinc finger SWIM domain-containing protein 8 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
E 108374313 zinc finger SWIM domain-containing protein 8-like K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108361423 cullin-3 isoform X1 K03869 CUL3; cullin 3
E 108373032 cullin-3-like K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 108373732 kelch-like protein 5 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 108361348 kelch-like protein 10 isoform X1 K10448 KLHL10; kelch-like protein 10
E 108367931 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 108370662 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 108380160 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 108377457 kelch-like protein 18 K10455 KLHL18; kelch-like protein 18
E 108366667 kelch-like ECH-associated protein 1 K10456 KLHL19; kelch-like protein 19
E 108378179 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 108382325 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 108370067 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 108370748 actin-binding protein IPP isoform X1 K13956 IPP; actin-binding protein IPP
E 108367615 BTB/POZ domain-containing protein 2-like K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 108379782 BTB/POZ domain-containing protein 6-like K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 108380048 BTB/POZ domain-containing protein 6-B-like isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 108360430 BTB/POZ domain-containing protein 6-B-like isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 108376703 BTB/POZ domain-containing protein 7-like K10479 BTBD7; BTB/POZ domain-containing protein 7
E 108379662 BTB/POZ domain-containing protein 7-like K10479 BTBD7; BTB/POZ domain-containing protein 7
E 108370447 BTB/POZ domain-containing protein 9 isoform X1 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 108382814 protein germ cell-less-like K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 108372059 ankyrin repeat and BTB/POZ domain-containing protein 2 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 108380819 rho-related BTB domain-containing protein 1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 108374886 rho-related BTB domain-containing protein 2-like K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 108362549 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 108371301 BTB/POZ domain-containing protein kctd15-like K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 108362112 BTB/POZ domain-containing protein kctd15-like isoform X1 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 108373630 BTB/POZ domain-containing protein KCTD5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 108366053 BTB/POZ domain-containing protein KCTD3 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 108359516 BTB/POZ domain-containing protein KCTD12-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 108381056 BTB/POZ domain-containing protein KCTD12-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 108373562 BTB/POZ domain-containing protein KCTD12-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 108367388 BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 108380129 BTB/POZ domain-containing protein KCTD9-like K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 108366487 protein roadkill K10523 SPOP; speckle-type POZ protein
E 108381122 speckle-type POZ protein-like K10523 SPOP; speckle-type POZ protein
E 108373498 speckle-type POZ protein B-like K10523 SPOP; speckle-type POZ protein
E 108374183 protein roadkill-like K10523 SPOP; speckle-type POZ protein
E 108375843 protein roadkill-like K10523 SPOP; speckle-type POZ protein
E 108369550 leucine-zipper-like transcriptional regulator 1 isoform X1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 108381253 cullin-4A-like K10609 CUL4; cullin 4
E 108372663 cullin-4B-like K10609 CUL4; cullin 4
E 108358531 cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 108362985 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 108371651 DET1- and DDB1-associated protein 1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 108370604 protein cereblon homolog isoform X1 K11793 CRBN; cereblon
E 108364151 protein mahjong isoform X1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 108363488 protein lethal(2)denticleless K11790 DTL; denticleless
E 108380724 DDB1- and CUL4-associated factor 6-like K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 108371421 DDB1- and CUL4-associated factor 7-like K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 108364402 DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 108372886 DDB1- and CUL4-associated factor 8-like isoform X1 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 108360402 WD and tetratricopeptide repeats protein 1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 108367313 DDB1- and CUL4-associated factor 10 homolog K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 108362206 DDB1- and CUL4-associated factor 11 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 108356620 DDB1- and CUL4-associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 108378612 DDB1- and CUL4-associated factor 13-like K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 108369646 DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 108363958 uncharacterized protein LOC108363958 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 108360504 bromodomain and WD repeat-containing protein 3 isoform X1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 108369259 WD repeat-containing protein 26 homolog K22382 WDR26; WD repeat-containing protein 26
E 108378853 WD repeat-containing protein 26-like K22382 WDR26; WD repeat-containing protein 26
E 108360578 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
E 108373556 RING-box protein 2 K10611 RBX2; RING-box protein 2
D Cullin
E 108364591 cullin-5 isoform X1 K10612 CUL5; cullin 5
D Adoptor protein
E 108379494 transcription elongation factor B polypeptide 1-like K03872 ELOC; elongin-C
E 108360493 transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 108373291 transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
E 108356966 transcription elongation factor B polypeptide 2-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 108356875 suppressor of cytokine signaling 6-like K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 108368316 uncharacterized protein LOC108368316 K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 108360160 protein gustavus K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 108380595 SPRY domain-containing SOCS box protein 4-like K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 108368053 SPRY domain-containing SOCS box protein 3 isoform X1 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 108371198 SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 108363182 ras-related protein Rab-40C isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 108355398 ras-related protein Rab-40C-like K07928 RAB40; Ras-related protein Rab-40
E 108365656 RING finger and SPRY domain-containing protein 1-like K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 108355214 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
E 108357450 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 108377436 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368697 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108368698 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E 108382225 RING-box protein 1A-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
D Cullin
E 108359323 anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 108371418 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 108364038 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 108364130 fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E 108354815 fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 108364792 cell division cycle protein 27 homolog K03350 APC3; anaphase-promoting complex subunit 3
E 108370174 anaphase-promoting complex subunit 4 isoform X1 K03351 APC4; anaphase-promoting complex subunit 4
E 108367565 anaphase-promoting complex subunit 5 isoform X1 K03352 APC5; anaphase-promoting complex subunit 5
E 108365998 cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 108373199 anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 108367175 cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 108359257 cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 108362483 anaphase-promoting complex subunit 10-like K03357 APC10; anaphase-promoting complex subunit 10
E 108373788 anaphase-promoting complex subunit 10-like K03357 APC10; anaphase-promoting complex subunit 10
E 108371816 anaphase-promoting complex subunit 13 isoform X1 K12456 APC13; anaphase-promoting complex subunit 13
E 108365407 anaphase-promoting complex subunit 15B isoform X1 K25228 APC15; anaphase-promoting complex subunit 15
C BRCC complex
D 108379236 DNA repair protein RAD51 homolog 1 isoform X1 K04482 RAD51; DNA repair protein RAD51
D 108372878 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 108359477 E3 ubiquitin-protein ligase RNF123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 108367906 ubiquitin-associated domain-containing protein 1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 108364452 uncharacterized protein LOC108364452 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 108361577 protein RMD5 homolog A K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 108354272 protein RMD5 homolog A-like K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 108367929 ran-binding protein 9-like K23334 RANBP9_10; Ran-binding protein 9/10
D 108358400 ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 108379501 armadillo repeat-containing protein 8-like K23336 ARMC8; armadillo repeat-containing protein 8
D 108366685 armadillo repeat-containing protein 8-like K23336 ARMC8; armadillo repeat-containing protein 8
D 108373967 muskelin isoform X1 K23337 MKLN1; muskelin
D 108361972 macrophage erythroblast attacher isoform X1 K18624 MAEA; macrophage erythroblast attacher
D 108365173 macrophage erythroblast attacher-like K18624 MAEA; macrophage erythroblast attacher
D 108372421 glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 108366219 glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 108382576 glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 108376160 protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 108365877 protein yippee K23339 YPEL5; protein yippee-like 5
D 108365878 protein yippee K23339 YPEL5; protein yippee-like 5
D 108369259 WD repeat-containing protein 26 homolog K22382 WDR26; WD repeat-containing protein 26
D 108378853 WD repeat-containing protein 26-like K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 108355051 erlin-1-like K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 108371661 protein Lilipod-like isoform X1 K25215 LMBR1L; protein LMBR1L
D 108374171 protein Lilipod isoform X1 K25215 LMBR1L; protein LMBR1L
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 108374253 cullin-associated NEDD8-dissociated protein 1-like K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 108359147 cullin-associated NEDD8-dissociated protein 1 isoform X1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 108371030 COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 108378012 COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 108368143 COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 108357677 COMM domain-containing protein 4-like K22560 COMMD4; COMM domain containing 4
D 108358183 COMM domain-containing protein 5 K22561 COMMD5; COMM domain containing 5
D 108368561 uncharacterized protein LOC108368561 K22564 COMMD8; COMM domain containing 8
D 108379726 COMM domain-containing protein 10 K22566 COMMD10; COMM domain containing 10
D 108368638 coiled-coil domain-containing protein 22 homolog K23343 CCDC22; coiled-coil domain-containing protein 22
D 108376307 DDRGK domain-containing protein 1-like K23344 DDRGK1; DDRGK domain-containing protein 1
D 108380392 DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 108363904 uncharacterized protein LOC108363904 isoform X1 K23345 GLMN; glomulin
D 108380672 UBX domain-containing protein 7-like K24350 UBXN7; UBX domain-containing protein 7
D 108354047 UBX domain-containing protein 7-like K24350 UBXN7; UBX domain-containing protein 7
D 108364352 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 108363791 protein lingerer isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 108376998 uncharacterized protein LOC108376998 K26546 Dlish; SH3 domain-containing protein Dlish
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 108380443 ubiquitin carboxyl-terminal hydrolase calypso K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 108365077 ubiquitin carboxyl-terminal hydrolase isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 108378888 ubiquitin carboxyl-terminal hydrolase isozyme L5-like K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
D 108382522 ubiquitin carboxyl-terminal hydrolase isozyme L5-like K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
D 108382573 ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 108370652 ubiquitin carboxyl-terminal hydrolase CYLD-like K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 108373990 uncharacterized protein LOC108373990 isoform X1 K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 108371490 uncharacterized protein LOC108371490 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 108372344 uncharacterized protein YMR317W-like K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 108379805 ubiquitin carboxyl-terminal hydrolase 3-like K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 108364222 ubiquitin carboxyl-terminal hydrolase 5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 108375135 ubiquitin carboxyl-terminal hydrolase 5-like K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 108377430 ubiquitin carboxyl-terminal hydrolase 7-like K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 108380415 ubiquitin carboxyl-terminal hydrolase 7-like K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 108381107 ubiquitin carboxyl-terminal hydrolase 7-like K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 108374514 ubiquitin carboxyl-terminal hydrolase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 108359366 ubiquitin carboxyl-terminal hydrolase 8 isoform X1 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 108373855 probable ubiquitin carboxyl-terminal hydrolase FAF K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 108376667 ubiquitin carboxyl-terminal hydrolase 46-like K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 108372942 ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 108355909 ubiquitin carboxyl-terminal hydrolase 14-like K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 108362302 ubiquitin carboxyl-terminal hydrolase 45 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 108363999 ubiquitin carboxyl-terminal hydrolase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 108361683 ubiquitin carboxyl-terminal hydrolase nonstop K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 108381479 ubiquitin carboxyl-terminal hydrolase 22-A-like K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 108362506 ubiquitin carboxyl-terminal hydrolase 30 homolog K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 108365682 ubiquitin carboxyl-terminal hydrolase 31 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 108365187 ubiquitin carboxyl-terminal hydrolase 34 isoform X1 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 108376118 ubiquitin carboxyl-terminal hydrolase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 108372437 ubiquitin carboxyl-terminal hydrolase 64E isoform X1 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
C OTU
D 108374077 ubiquitin thioesterase otubain-like K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 108369215 OTU domain-containing protein 5-A K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 108365178 OTU domain-containing protein 5-B-like K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 108370778 OTU domain-containing protein 6B K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 108372979 OTU domain-containing protein 6B-like K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 108370563 ubiquitin thioesterase trabid K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 108359390 josephin-like protein isoform X1 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 108369306 protein FAM63A-like K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D 108368497 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 108380771 26S proteasome non-ATPase regulatory subunit 14-like K03030 PSMD14; 26S proteasome regulatory subunit N11
D 108380365 STAM-binding protein-like K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D 108360496 desumoylating isopeptidase 2 isoform X1 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
D 108357915 desumoylating isopeptidase 2-like K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C 108364159 uncharacterized protein LOC108364159 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 108373936 sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 108365077 ubiquitin carboxyl-terminal hydrolase isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 108360885 uncharacterized protein LOC108360885 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 108381110 uncharacterized protein LOC108381110 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D 108367047 COP9 signalosome complex subunit 1b K12175 GPS1; COP9 signalosome complex subunit 1
D 108365120 COP9 signalosome complex subunit 1-like K12175 GPS1; COP9 signalosome complex subunit 1
D 108378841 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 108374285 COP9 signalosome complex subunit 2-like K12176 COPS2; COP9 signalosome complex subunit 2
D 108368853 COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 108373267 COP9 signalosome complex subunit 3-like K12177 COPS3; COP9 signalosome complex subunit 3
D 108359703 COP9 signalosome complex subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D 108355358 COP9 signalosome complex subunit 4-like K12178 COPS4; COP9 signalosome complex subunit 4
D 108381419 COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 108354782 COP9 signalosome complex subunit 5-like K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 108376441 COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 108371925 COP9 signalosome complex subunit 6-like K12179 COPS6; COP9 signalosome complex subunit 6
D 108373563 COP9 signalosome complex subunit 7b-like K12180 COPS7; COP9 signalosome complex subunit 7
D 108362671 COP9 signalosome complex subunit 7 isoform X1 K12180 COPS7; COP9 signalosome complex subunit 7
D 108373252 COP9 signalosome complex subunit 8-like isoform X1 K12181 COPS8; COP9 signalosome complex subunit 8
D 108377916 COP9 signalosome complex subunit 8-like K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 1, 2024