+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Singulisphaera acidiphila
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C Sinac_6087 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C Sinac_2635 prepilin signal peptidase PulO-like peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C Sinac_6495 prepilin signal peptidase PulO-like peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C Sinac_1935 Flp pilus assembly protein, protease CpaA K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
C Sinac_4498 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C Sinac_2340 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C Sinac_6680 putative glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
B Family C44
C Sinac_2274 glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C Sinac_4868 glutamate synthase family protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C Sinac_6373 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C Sinac_2659 asparagine synthase, glutamine-hydrolyzing K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C Sinac_2476 asparagine synthase, glutamine-hydrolyzing K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C Sinac_5187 asparagine synthase, glutamine-hydrolyzing K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C Sinac_3906 asparagine synthase, glutamine-hydrolyzing K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C Sinac_5465 asparagine synthase, glutamine-hydrolyzing K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C Sinac_0268 asparagine synthase, glutamine-hydrolyzing K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
C Sinac_2339 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 IAL; isopenicillin-N N-acyltransferase like protein
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C Sinac_1710 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124]
C Sinac_6090 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124]
C Sinac_4134 transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K18199 inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C Sinac_0789 putative metal-dependent membrane protease K07052 K07052; CAAX protease family protein
C Sinac_0849 CAAX prenyl protease-related protein K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C Sinac_5685 aminopeptidase N K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C Sinac_6689 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
C Sinac_2369 oligoendopeptidase F K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
B Family M3
C Sinac_1523 oligoendopeptidase, M3 family K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
C Sinac_4737 oligoendopeptidase, pepF/M3 family K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
C Sinac_5355 putative metalloendopeptidase K07386 pepO; putative endopeptidase [EC:3.4.24.-]
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
B Family M16: pitrilysin family
C Sinac_5560 putative Zn-dependent peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
C Sinac_5561 putative Zn-dependent peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
C Sinac_1308 putative Zn-dependent peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
C Sinac_0248 putative Zn-dependent peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
C Sinac_0625 putative Zn-dependent peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
C Sinac_3524 putative Zn-dependent peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C Sinac_4936 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
C Sinac_0908 Zn-dependent dipeptidase, microsomal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C Sinac_1040 Zn-dependent dipeptidase, microsomal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C Sinac_1337 Zn-dependent dipeptidase, microsomal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C Sinac_3887 Zn-dependent dipeptidase, microsomal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C Sinac_5558 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]
B Family M23
B Family M24
C Sinac_0465 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C Sinac_3769 Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
C Sinac_6856 putative aminopeptidase K01301 NAALAD; N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21]
C Sinac_5126 putative aminopeptidase K00683 QPCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]
B Family M29: aminopeptidase T family
C Sinac_6181 leucyl aminopeptidase (aminopeptidase T) K19689 ampS; aminopeptidase [EC:3.4.11.-]
C Sinac_6795 leucyl aminopeptidase (aminopeptidase T) K19689 ampS; aminopeptidase [EC:3.4.11.-]
B Family M32: carboxypeptidase Taq family
C Sinac_2122 Zn-dependent carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C Sinac_1779 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
C Sinac_5400 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C Sinac_3192 Zn-dependent protease with chaperone function K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
B Family M49: dipeptidyl-peptidase III family
C Sinac_4683 Peptidase family M49 K01277 DPP3; dipeptidyl-peptidase III [EC:3.4.14.4]
B Family M50: S2P protease family
C Sinac_3138 Zn-dependent protease K06402 spoIVFB; stage IV sporulation protein FB [EC:3.4.24.-]
C Sinac_2332 RIP metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
C Sinac_6853 multidrug resistance efflux pump K16922 yydH; putative peptide zinc metalloprotease protein
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
C Sinac_2337 antirepressor regulating drug resistance protein K02172 blaR1; bla regulator protein blaR1
C Sinac_6062 antirepressor regulating drug resistance protein K02172 blaR1; bla regulator protein blaR1
C Sinac_4351 antirepressor regulating drug resistance protein K02172 blaR1; bla regulator protein blaR1
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
B Family M90
C Sinac_3436 hypothetical protein K09933 mtfA; MtfA peptidase
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
C Sinac_4604 L-aminopeptidase/D-esterase K01266 dmpA; D-aminopeptidase [EC:3.4.11.19]
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C Sinac_4277 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_1562 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_0451 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_6094 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_5079 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_5148 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_6470 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_7566 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_6514 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_6779 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_0780 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
C Sinac_0130 trypsin-like serine protease with C-terminal PDZ domain K04771 degP; serine protease Do [EC:3.4.21.107]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
B Family S9: prolyl oligopeptidase family
C Sinac_5044 serine protease, S9A family peptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C Sinac_5996 dipeptidyl aminopeptidase/acylaminoacyl peptidase K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C Sinac_2801 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
C Sinac_6651 D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C Sinac_2573 protease subunit of ATP-dependent protease K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
C Sinac_2574 protease subunit of ATP-dependent protease K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C Sinac_3136 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C Sinac_5754 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C Sinac_3206 SOS regulatory protein LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
B Family S28
B Family S31
B Family S32
B Family S33
C Sinac_5915 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
B Family S41: C-terminal processing peptidase family
C Sinac_0729 periplasmic protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C Sinac_5853 C-terminal processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C Sinac_5296 C-terminal processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C Sinac_4730 Tol biopolymer transport system, periplasmic component-related protein K08676 tri; tricorn protease [EC:3.4.21.-]
B Family S45
C Sinac_6391 penicilin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11]
B Family S49: protease IV family
C Sinac_5875 ClpP class periplasmic serine protease K04773 sppA; protease IV [EC:3.4.21.-]
B Family S50
B Family S51
C Sinac_0837 cyanophycinase K13282 cphB; cyanophycinase [EC:3.4.15.6]
B Family S53
B Family S54: Rhomboid family
C Sinac_5702 uncharacterized membrane protein K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]
C Sinac_5094 putative membrane protein K07059 K07059; rhomboid family protein
C Sinac_1327 putative membrane protein K07059 K07059; rhomboid family protein
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
C Sinac_3561 putative MccF-like protein (microcin C7 resistance) K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C Sinac_5341 ATP-dependent protease HslVU, peptidase subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
B Family T3: gamma-glutamyltransferase family
C Sinac_2586 gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C Sinac_6445 gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
C Sinac_5945 collagenase-like protease K08303 prtC; U32 family peptidase [EC:3.4.-.-]
B Family U62
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
C Sinac_0870 large extracellular alpha-helical protein K06894 yfhM; alpha-2-macroglobulin
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C Sinac_7087 membrane protease subunit, stomatin/prohibitin K04087 hflC; modulator of FtsH protease HflC
C Sinac_7088 HflK protein K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024
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Classification taken and modified from MEROPS