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Transfer RNA Biogenesis - Sulfolobus acidocaldarius DSM 639
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D Saci_0589 conserved protein K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Saci_0614 conserved protein K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Saci_0615 conserved RNase_P_p30-like protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Saci_0033 conserved protein K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D Saci_1284 metallo-beta-lactamase superfamily protein K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D Saci_1317 universally conserved protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D Saci_0565 conserved Archaeal protein K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D Saci_0685 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D Saci_0920 GTP-binding protein 1 K03231 EEF1A; elongation factor 1-alpha
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Saci_1519 glutamyl- and glutaminyl-tRNA synthetases K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Saci_1553 bifunctional aminoacyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Saci_0599 ileS; isoleucine-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Saci_0373 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Saci_1572 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Saci_1544 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Saci_1396 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Saci_0067 lysS; lysyl-tRNA synthetase type II K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
C Other AARSs
D Saci_1168 alanyl-tRNA like protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Saci_1455 alaRS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Saci_0862 glyRS; glycyl-tRNA synthetase class II K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Saci_1261 threonine-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Saci_1584 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Saci_0152 cysRS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Saci_1430 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Saci_0663 histidyl tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Saci_1511 phenylalanyl-tRNA synthetase K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Saci_1510 phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Saci_0076 tys1; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Saci_0450 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D Saci_0042 conserved Archaeal protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D Saci_1032 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
D Saci_0962 universally conserved protein K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D Saci_1343 trm1; N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D Saci_0559 conserved Archaeal protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Saci_0844 conserved Archaeal protein K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D Saci_1331 conserved protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D Saci_0030 conserved protein K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D Saci_1603 conserved Archaeal protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
C Psudouridine synthases
D Saci_0811 tru; tRNA pseudouridine synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Saci_0769 conserved Archaeal protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
C KEOPS/EKC complex
D Saci_0850 serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Saci_0851 O-sialoglycoprotein endopeptidase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Elongator complex
D Saci_1044 conserved Archaeal protein K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
C Elongator related proteins
C Other tRNA modification factors
D Saci_1642 universally conserved protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Saci_0902 conserved protein K06963 TAN1; tRNA acetyltransferase TAN1
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D Saci_1284 metallo-beta-lactamase superfamily protein K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D Saci_1288 tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
B tRNA spricing factors
C tRNA splicing endonucleases
D Saci_0664 conserved Archaeal protein K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D Saci_0858 tRNA-intron endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
C tRNA splicing ligases
D Saci_1317 universally conserved protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D Saci_1287 2',5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Saci_0373 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Saci_1572 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Saci_1553 bifunctional aminoacyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D Saci_0076 tys1; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Saci_0450 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Saci_1261 threonine-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Saci_0599 ileS; isoleucine-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Saci_0067 lysS; lysyl-tRNA synthetase type II K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Saci_1168 alanyl-tRNA like protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Saci_1455 alaRS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Saci_1430 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Saci_1544 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Saci_1584 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Saci_0152 cysRS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Saci_1519 glutamyl- and glutaminyl-tRNA synthetases K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Saci_1396 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Saci_1511 phenylalanyl-tRNA synthetase K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Saci_1510 phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Saci_0663 histidyl tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Saci_0768 aspS; aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
C Trans-editing factors
D Saci_0042 conserved Archaeal protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D Saci_0717 NOL1/NOP2/sun family protein K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D Saci_1677 conserved Archaeal protein K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221]
D Saci_1283 RNA methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D Saci_0653 conserved Archaeal protein K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
C Psudouridine synthases
D Saci_0811 tru; tRNA pseudouridine synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Saci_0769 conserved Archaeal protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D Saci_0378 pP-loop family protein K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
C KEOPS/EKC complex
D Saci_0850 serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Saci_0851 O-sialoglycoprotein endopeptidase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D Saci_0280 conserved protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Saci_1604 conserved Archaeal protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Saci_0659 queuine tRNA-ribosyltransferase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D Saci_2336 thiI; thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Saci_0732 conserved Archaeal protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D Saci_0127 conserved protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D Saci_0428 hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D Saci_1642 universally conserved protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025