+F Repair protein KO
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DNA Repair and Recombination Proteins - Staphylococcus aureus subsp. aureus MW2 (CA-MRSA)
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MW2468 adaB; probable methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MW0653 ORFID:MW0653; hypothetical protein, similar to deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MW0536 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MW2265 ORFID:MW2265; hypothetical protein, similar to DNA-3-methyladenine glycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MW1808 ORFID:MW1808; hypothetical protein, similar to A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MW1342 nth; endonuclease-like protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MW1732 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MW2410 ORFID:MW2410; hypothetical protein, similar to mutator protein mutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MW2468 adaB; probable methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MW0653 ORFID:MW0653; hypothetical protein, similar to deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MW0536 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MW2265 ORFID:MW2265; hypothetical protein, similar to DNA-3-methyladenine glycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MW1808 ORFID:MW1808; hypothetical protein, similar to A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MW1608 tag; DNA-3-methyladenine glycosidase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MW1632 ORFID:MW1632; hypothetical protein, similar to formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MW1342 nth; endonuclease-like protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MW1509 ORFID:MW1509; hypothetical protein, similar to endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E MW1586 ORFID:MW1586; hypothetical protein, similar to single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MW1845 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MW1633 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MW0721 uvrA; exinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E MW0720 uvrB; exinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E MW1029 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E MW1846 pcrA; ATP-depentend DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MW1633 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MW1845 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MW0497 rpoB; RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MW0498 rpoC; RNA polymerase beta-prime chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MW2143 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MW2052 rpoE; probable DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F MW1093 conserved hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MW0458 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MW1178 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E MW1027 mutS2; MutS-like protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E MW1179 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MW1476 ORFID:MW1476; hypothetical protein, similar to exodeoxyribonuclease large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MW1475 ORFID:MW1475; hypothetical protein, similar to exodeoxyribonuclease, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MW1646 dnaE; DNA POLYMERASE III ALPHA SUBUNIT K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MW1147 polC; DNA polymerase III alpha chain PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E MW0002 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MW1538 conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MW0439 holB; probable DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MW1835 ORFID:MW1835; hypothetical protein, similar to DNA polymerase III, alpha chain PolC type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MW0433 dnaX; DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MW1845 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MW1846 pcrA; ATP-depentend DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MW0342 ssb; single-strand DNA-binding protein of phage phi Sa 2mw K03111 ssb; single-strand DNA-binding protein
E MW1921 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MW2021 ORFID:MW2021; hypothetical protein, similar to single strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MW1569 ORFID:MW1569; hypothetical protein, similar to deoxyribonuclease K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MW1168 recA; RecA protein K03553 recA; recombination protein RecA
E MW1592 ruvA; holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E MW1591 ruvB; holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MW1095 priA; primosomal protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E MW1233 ORFID:MW1233; hypothetical protein, similar to exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E MW1232 ORFID:MW1232; hypothetical protein, similar to exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MW1168 recA; RecA protein K03553 recA; recombination protein RecA
E MW0481 radA; DNA repair protein homologue; ORFID:MW0481 K04485 radA; DNA repair protein RadA/Sms
E MW0004 recF; DNA repair and genetic recombination protein K03629 recF; DNA replication and repair protein RecF
E MW0043 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MW1110 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MW1586 ORFID:MW1586; hypothetical protein, similar to single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MW1518 ORFID:MW1518; hypothetical protein, similar to DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MW0435 recR; recombination protein K06187 recR; recombination protein RecR
E MW1472 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E MW1339 recU; ORFID:MW1339; recombination protein U homolog K03700 recU; recombination protein U
E MW1592 ruvA; holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E MW1591 ruvB; holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E MW0849 ORFID:MW0849; hypothetical protein, similar to ATP-dependent nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E MW0848 ORFID:MW0848; hypothetical protein, similar to ATP-dependent nuclease subunit K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E MW1233 ORFID:MW1233; hypothetical protein, similar to exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E MW1232 ORFID:MW1232; hypothetical protein, similar to exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MW0006 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MW0005 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MW1133 DNA topoisomerase I topA homolog; ORFID:MW1133 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MW1362 hu; DNA-binding protein II K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MW1923 hypothetical protein K07455 recT; recombination protein RecT
F MW1586 ORFID:MW1586; hypothetical protein, similar to single-strand DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MW1518 ORFID:MW1518; hypothetical protein, similar to DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MW0435 recR; recombination protein K06187 recR; recombination protein RecR
F MW1845 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MW0683 recQ; probable DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MW1370 probable ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MW0721 uvrA; exinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F MW0720 uvrB; exinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MW1836 ORFID:MW1836; hypothetical protein, similar to DNA-damage inducible protein P K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D MW1168 recA; RecA protein K03553 recA; recombination protein RecA
D MW1226 lexA; SOS regulatory LexA protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D MW1472 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D MW0342 ssb; single-strand DNA-binding protein of phage phi Sa 2mw K03111 ssb; single-strand DNA-binding protein
D MW1921 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MW2021 ORFID:MW2021; hypothetical protein, similar to single strand DNA binding protein K03111 ssb; single-strand DNA-binding protein
D MW1813 conserved hypothetical protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D MW1026 DNA-dependent DNA polymerase beta chain K02347 polX; DNA polymerase (family X)
C DNA helicases
D MW1345 dinG; probable ATP-dependent DNA helicase dinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MW1732 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MW2410 ORFID:MW2410; hypothetical protein, similar to mutator protein mutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MW0693 nrdE; ribonuceloside diphosphate reductase major subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MW0694 nrdF; ribonucleoside-diphosphate reductase minor subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MW1647 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025