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Transfer RNA Biogenesis - Sylvia atricapilla (blackcap)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D 136370499 POP1; (RefSeq) ribonucleases P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 136366676 POP4; (RefSeq) ribonuclease P protein subunit p29 isoform X1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 136368856 POP5; (RefSeq) ribonuclease P/MRP protein subunit POP5 isoform X1 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 136364182 RPP30; (RefSeq) ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 136365874 RPP14; (RefSeq) ribonuclease P protein subunit p14 K14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
D 136367207 RPP25; (RefSeq) ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 136373511 RPP25L; (RefSeq) ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 136359930 RPP38; (RefSeq) ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 136364993 RPP40; (RefSeq) ribonuclease P protein subunit p40 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D 136369360 ELAC2; (RefSeq) zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 136359314 RNASET2; (RefSeq) ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 136367934 PTCD1; (RefSeq) pentatricopeptide repeat-containing protein 1, mitochondrial K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
C CCA adding factors
D 136366236 TRNT1; (RefSeq) CCA tRNA nucleotidyltransferase 1, mitochondrial isoform X1 K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
D 136366094 TSEN2; (RefSeq) tRNA-splicing endonuclease subunit Sen2 K15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]
D 136364681 TSEN15; (RefSeq) tRNA-splicing endonuclease subunit Sen15 K15324 TSEN15; tRNA-splicing endonuclease subunit Sen15
D 136369266 TSEN54; (RefSeq) tRNA-splicing endonuclease subunit Sen54 isoform X1 K15326 TSEN54; tRNA-splicing endonuclease subunit Sen54
C tRNA splicing ligase complex
D 136361818 RTCB; (RefSeq) RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D 136357975 C2H2orf49; (RefSeq) ashwin K15432 ASW; ashwin
D 136362729 RTRAF; (RefSeq) RNA transcription, translation and transport factor protein isoform X1 K15433 CGI99; RLL motif containing protein 1
D 136362683 FAM98B; (RefSeq) protein FAM98B K15434 FAM98B; protein FAM98B
D 136358770 DDX1; (RefSeq) ATP-dependent RNA helicase DDX1 isoform X1 K13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]
D 136371138 ZBTB8OS; (RefSeq) protein archease isoform X1 K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D 136369115 RAN; (RefSeq) GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
D 136361295 XPOT; (RefSeq) exportin-T K14288 XPOT; exportin-T
D 136359691 XPO1; (RefSeq) exportin-1 K14290 XPO1; exportin-1
D 136359325 XPO5; (RefSeq) exportin-5 isoform X1 K14289 XPO5; exportin-5
D 136358886 EEF1A1; (RefSeq) elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
D 136368552 EEF1A2; (RefSeq) elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
D 136361826 GTPBP1; (RefSeq) GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C tRNA import factors
D 136361198 TNPO3; (RefSeq) transportin-3 K15436 TRPO3; transportin-3
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 136359519 EPRS1; (RefSeq) bifunctional glutamate/proline--tRNA ligase isoform X1 K14163 EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
D 136368033 EARS2; (RefSeq) nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 136365113 PARS2; (RefSeq) probable proline--tRNA ligase, mitochondrial K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D 136359521 IARS2; (RefSeq) isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 136366081 IARS1; (RefSeq) isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 136362720 LARS2; (RefSeq) LOW QUALITY PROTEIN: leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 136367657 LARS1; (RefSeq) leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 136370434 MARS2; (RefSeq) methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 136372833 MARS1; (RefSeq) methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 136366188 QARS1; (RefSeq) LOW QUALITY PROTEIN: glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 136358935 RARS2; (RefSeq) probable arginine--tRNA ligase, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 136367392 RARS1; (RefSeq) arginine--tRNA ligase, cytoplasmic isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 136366356 KARS1; (RefSeq) lysine--tRNA ligase isoform X1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 136363711 DARS1; (RefSeq) aspartate--tRNA ligase, cytoplasmic K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 136364741 DARS2; (RefSeq) aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 136360524 AIMP1; (RefSeq) aminoacyl tRNA synthase complex-interacting multifunctional protein 1 K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
D 136367861 AIMP2; (RefSeq) aminoacyl tRNA synthase complex-interacting multifunctional protein 2 K15438 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2
D 136364781 EEF1E1; (RefSeq) eukaryotic translation elongation factor 1 epsilon-1 K15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1
C Other AARSs
D 136359402 AARS2; (RefSeq) alanine--tRNA ligase, mitochondrial K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 136366556 AARS1; (RefSeq) alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 136374022 NARS1; (RefSeq) asparagine--tRNA ligase, cytoplasmic K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 136375634 NARS2; (RefSeq) asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 136357979 GARS1; (RefSeq) glycine--tRNA ligase isoform X1 K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 136367123 TARS3; (RefSeq) threonine--tRNA ligase 2, cytoplasmic K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 136372961 TARS2; (RefSeq) threonine--tRNA ligase, mitochondrial isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 136374312 TARS1; (RefSeq) threonine--tRNA ligase 1, cytoplasmic isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 136371627 SARS1; (RefSeq) serine--tRNA ligase, cytoplasmic K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 136358022 CARS2; (RefSeq) probable cysteine--tRNA ligase, mitochondrial isoform X1 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 136362412 CARS1; (RefSeq) cysteine--tRNA ligase, cytoplasmic isoform X1 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 136367363 histidine--tRNA ligase, cytoplasmic-like K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 136367364 histidine--tRNA ligase, cytoplasmic isoform X1 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 136364925 FARS2; (RefSeq) phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 136365634 FARSB; (RefSeq) phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 136361088 YARS2; (RefSeq) tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 136371318 YARS1; (RefSeq) tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 136362924 WARS1; (RefSeq) tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 136375584 WARS2; (RefSeq) tryptophan--tRNA ligase, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D 136359596 DTD1; (RefSeq) D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 136363066 DTD2; (RefSeq) D-aminoacyl-tRNA deacylase 2 isoform X1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 136372253 AARSD1; (RefSeq) alanyl-tRNA editing protein Aarsd1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D 136371336 TRNAU1AP; (RefSeq) tRNA selenocysteine 1-associated protein 1 isoform X1 K25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1
D 136373568 HINT1; (RefSeq) adenosine 5'-monophosphoramidase HINT1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 136374370 HINT2; (RefSeq) adenosine 5'-monophosphoramidase HINT2 isoform X1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 136359070 HINT3; (RefSeq) adenosine 5'-monophosphoramidase HINT3 K12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
D 136366357 ADAT1; (RefSeq) LOW QUALITY PROTEIN: tRNA-specific adenosine deaminase 1 K15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
D 136359172 ADAT2; (RefSeq) tRNA-specific adenosine deaminase 2 K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
C Dihydorouridine synthases
D 136369382 DUS1L; (RefSeq) tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like isoform X1 K05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]
D 136366628 DUS2; (RefSeq) tRNA-dihydrouridine(20) synthase [NAD(P)+]-like K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D 136371793 DUS3L; (RefSeq) tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
D 136361024 DUS4L; (RefSeq) tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like K05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]
C Methylthiotransferase
D 136364215 CDKAL1; (RefSeq) threonylcarbamoyladenosine tRNA methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D 136368940 TRMT2A; (RefSeq) tRNA (uracil-5-)-methyltransferase homolog A K15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]
D 136370524 TRMT2B; (RefSeq) LOW QUALITY PROTEIN: tRNA (uracil-5-)-methyltransferase homolog B K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D 136359253 TARBP1; (RefSeq) LOW QUALITY PROTEIN: probable methyltransferase TARBP1 K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D 136365965 NSUN2; (RefSeq) RNA cytosine C(5)-methyltransferase NSUN2 K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D 136373270 NSUN3; (RefSeq) tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 136359681 NSUN6; (RefSeq) tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 K21971 NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]
D 136362788 TRMT5; (RefSeq) tRNA (guanine(37)-N1)-methyltransferase isoform X1 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D 136359581 TRMT61B; (RefSeq) tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial isoform X1 K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 136362840 TRMT61A; (RefSeq) tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 136359626 TRMT6; (RefSeq) tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D 136372733 METTL1; (RefSeq) tRNA (guanine-N(7)-)-methyltransferase isoform X1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 136372285 tRNA N(3)-methylcytidine methyltransferase METTL2-like isoform X1 K24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]
D 136362224 METTL6; (RefSeq) tRNA N(3)-methylcytidine methyltransferase METTL6 K00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
D 136357589 ALKBH8; (RefSeq) alkylated DNA repair protein alkB homolog 8 K10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]
D 136360556 TRMT10A; (RefSeq) tRNA methyltransferase 10 homolog A K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 136373633 TRMT10B; (RefSeq) tRNA methyltransferase 10 homolog B K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 136359071 TRMT11; (RefSeq) tRNA (guanine(10)-N2)-methyltransferase homolog isoform X1 K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D 136365019 TRMT13; (RefSeq) tRNA:m(4)X modification enzyme TRM13 homolog isoform X1 K15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]
D 136358192 WDR4; (RefSeq) tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 K15443 TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
D 136366220 THUMPD3; (RefSeq) tRNA (guanine(6)-N2)-methyltransferase THUMP3 isoform X1 K28362 THUMPD3; tRNA (guanine(6/7)-N(2))-methyltransferase [EC:2.1.1.256 2.1.1.-]
D 136359754 TRDMT1; (RefSeq) tRNA (cytosine(38)-C(5))-methyltransferase isoform X1 K15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]
D 136369970 TYW1B; (RefSeq) S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B isoform X1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D 136374231 tRNA wybutosine-synthesizing protein 2 homolog isoform X1 K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D 136365035 TYW3; (RefSeq) tRNA wybutosine-synthesizing protein 3 homolog isoform X1 K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D 136358273 LCMT2; (RefSeq) tRNA wybutosine-synthesizing protein 4 isoform X1 K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
D 136363388 TYW5; (RefSeq) tRNA wybutosine-synthesizing protein 5 K18066 TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]
D 136372771 BCDIN3D; (RefSeq) RNA 5'-monophosphate methyltransferase K25191 BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 136368957 PUS1; (RefSeq) pseudouridylate synthase 1 homolog K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 136370920 PUS3; (RefSeq) tRNA pseudouridine(38/39) synthase K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D 136364011 TRUB1; (RefSeq) LOW QUALITY PROTEIN: pseudouridylate synthase TRUB1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 136361040 PUS7; (RefSeq) pseudouridylate synthase 7 homolog isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 136361265 PUS7L; (RefSeq) pseudouridylate synthase PUS7L isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 136359701 PUS10; (RefSeq) tRNA pseudouridine synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D 136370950 RPUSD4; (RefSeq) pseudouridylate synthase RPUSD4, mitochondrial K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
C Thiolation factors
D 136361007 TRMU; (RefSeq) mitochondrial tRNA-specific 2-thiouridylase 1 isoform X1 K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D 136366419 CTU2; (RefSeq) cytoplasmic tRNA 2-thiolation protein 2 isoform X1 K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D 136368365 NFS1; (RefSeq) cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 136369678 URM1; (RefSeq) ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
D 136368626 MOCS3; (RefSeq) adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D 136368436 TP53RK; (RefSeq) EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 136363351 OSGEPL1; (RefSeq) tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 136361005 TPRKB; (RefSeq) EKC/KEOPS complex subunit TPRKB K15901 TPRKB; EKC/KEOPS complex subunit TPRKB/CGI121
C Elongator complex
D 136373503 ELP1; (RefSeq) LOW QUALITY PROTEIN: elongator complex protein 1 K11373 ELP1; elongator complex protein 1
D 136366531 ELP2; (RefSeq) elongator complex protein 2 K11374 ELP2; elongator complex protein 2
D 136358661 elongator complex protein 3-like isoform X1 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D 136358666 ELP3; (RefSeq) elongator complex protein 3 isoform X1 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D 136362184 ELP4; (RefSeq) elongator complex protein 4 K11375 ELP4; elongator complex protein 4
D 136357813 ELP6; (RefSeq) LOW QUALITY PROTEIN: elongator complex protein 6 K11377 ELP6; elongator complex protein 6
C Elongator related proteins
D 136361558 DPH3; (RefSeq) diphthamide biosynthesis protein 3 K15455 DPH3; diphthamide biosynthesis protein 3
D 136365149 KTI12; (RefSeq) protein KTI12 homolog K15456 KTI12; protein KTI12
C Other tRNA modification factors
D 136371223 YRDC; (RefSeq) threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D 136371373 TRIT1; (RefSeq) tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 136358884 MTO1; (RefSeq) protein MTO1 homolog, mitochondrial K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 136375056 QTRT1; (RefSeq) queuine tRNA-ribosyltransferase catalytic subunit 1 K00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]
D 136375442 QTRT2; (RefSeq) queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1 K15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit
D 136361104 SEPHS1; (RefSeq) selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 136374836 selenide, water dikinase 1-like K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 136367831 THUMPD1; (RefSeq) THUMP domain-containing protein 1 K06963 TAN1; tRNA acetyltransferase TAN1
D 136367536 THG1L; (RefSeq) probable tRNA(His) guanylyltransferase isoform X1 K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D 136363975 ATE1; (RefSeq) arginyl-tRNA--protein transferase 1 isoform X1 K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
D 136365881 DALRD3; (RefSeq) DALR anticodon-binding domain-containing protein 3 K24973 DALRD3; DALR anticodon-binding domain-containing protein 3
B tRNA degradation factors
C TRAMP complex
D 136365946 TENT4A; (RefSeq) terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 136366653 TENT4B; (RefSeq) terminal nucleotidyltransferase 4B K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 136374110 ZCCHC7; (RefSeq) zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
D 136373956 MTREX; (RefSeq) exosome RNA helicase MTR4 isoform X1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C Rapid tRNA decay (RTD) pathway factors
D 136365668 XRN1; (RefSeq) 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D 136359747 XRN2; (RefSeq) 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D 136359524 BPNT1; (RefSeq) 3'(2'),5'-bisphosphate nucleotidase 1 K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
D 136359955 ribonuclease CL2-like K16631 ANG; angiogenin [EC:3.1.27.-]
D 136364187 LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 5-like K24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D 136369360 ELAC2; (RefSeq) zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 136359314 RNASET2; (RefSeq) ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D 136366236 TRNT1; (RefSeq) CCA tRNA nucleotidyltransferase 1, mitochondrial isoform X1 K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D 136361818 RTCB; (RefSeq) RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 136362720 LARS2; (RefSeq) LOW QUALITY PROTEIN: leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 136367657 LARS1; (RefSeq) leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 136365113 PARS2; (RefSeq) probable proline--tRNA ligase, mitochondrial K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D 136361088 YARS2; (RefSeq) tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 136371318 YARS1; (RefSeq) tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 136362924 WARS1; (RefSeq) tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 136375584 WARS2; (RefSeq) tryptophan--tRNA ligase, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 136367123 TARS3; (RefSeq) threonine--tRNA ligase 2, cytoplasmic K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 136372961 TARS2; (RefSeq) threonine--tRNA ligase, mitochondrial isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 136374312 TARS1; (RefSeq) threonine--tRNA ligase 1, cytoplasmic isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 136359521 IARS2; (RefSeq) isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 136366081 IARS1; (RefSeq) isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 136366356 KARS1; (RefSeq) lysine--tRNA ligase isoform X1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 136359402 AARS2; (RefSeq) alanine--tRNA ligase, mitochondrial K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 136366556 AARS1; (RefSeq) alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 136370434 MARS2; (RefSeq) methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 136372833 MARS1; (RefSeq) methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 136371627 SARS1; (RefSeq) serine--tRNA ligase, cytoplasmic K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 136364741 DARS2; (RefSeq) aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 136358022 CARS2; (RefSeq) probable cysteine--tRNA ligase, mitochondrial isoform X1 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 136362412 CARS1; (RefSeq) cysteine--tRNA ligase, cytoplasmic isoform X1 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 136368033 EARS2; (RefSeq) nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 136366188 QARS1; (RefSeq) LOW QUALITY PROTEIN: glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 136358935 RARS2; (RefSeq) probable arginine--tRNA ligase, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 136367392 RARS1; (RefSeq) arginine--tRNA ligase, cytoplasmic isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 136364925 FARS2; (RefSeq) phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 136365634 FARSB; (RefSeq) phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 136367363 histidine--tRNA ligase, cytoplasmic-like K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 136367364 histidine--tRNA ligase, cytoplasmic isoform X1 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 136374022 NARS1; (RefSeq) asparagine--tRNA ligase, cytoplasmic K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 136375634 NARS2; (RefSeq) asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D 136359596 DTD1; (RefSeq) D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 136363066 DTD2; (RefSeq) D-aminoacyl-tRNA deacylase 2 isoform X1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 136372253 AARSD1; (RefSeq) alanyl-tRNA editing protein Aarsd1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D 136372733 METTL1; (RefSeq) tRNA (guanine-N(7)-)-methyltransferase isoform X1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
C Psudouridine synthases
D 136368957 PUS1; (RefSeq) pseudouridylate synthase 1 homolog K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 136364011 TRUB1; (RefSeq) LOW QUALITY PROTEIN: pseudouridylate synthase TRUB1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 136361040 PUS7; (RefSeq) pseudouridylate synthase 7 homolog isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 136361265 PUS7L; (RefSeq) pseudouridylate synthase PUS7L isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D 136368365 NFS1; (RefSeq) cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D 136368436 TP53RK; (RefSeq) EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 136363351 OSGEPL1; (RefSeq) tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D 136358884 MTO1; (RefSeq) protein MTO1 homolog, mitochondrial K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 136371373 TRIT1; (RefSeq) tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 136371015 PTS; (RefSeq) 6-pyruvoyl tetrahydrobiopterin synthase isoform X1 K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D 136361104 SEPHS1; (RefSeq) selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 136374836 selenide, water dikinase 1-like K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 136371223 YRDC; (RefSeq) threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
C 136359712 PNPT1; (RefSeq) polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025