+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Staphylococcus aureus USA300-ISMMS1 (MRSA)</h2>
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A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    AZ30_11095 UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    AZ30_11215 UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    AZ30_03835 murB; UDP-N-acetylenolpyruvoylglucosamine reductase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    AZ30_08805 UDP-N-acetylmuramate--alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    AZ30_05670 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    AZ30_04840 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase	K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] 
C    AZ30_11015 ddl; D-alanine--D-alanine ligase	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
C    AZ30_11940 aminoacyltransferase	K11693 femX; peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16] 
C    AZ30_06695 methicillin resistance protein	K11694 femA; peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17] 
C    AZ30_06700 methicillin resistance protein	K11695 femB; peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18] 
B  Racemase
C    AZ30_06815 alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    AZ30_10950 alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    AZ30_05500 glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
B  Glycosyltransferase
C    AZ30_05665 phospho-N-acetylmuramoyl-pentapeptide-transferase	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    AZ30_06925 UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
C    AZ30_03565 UDP pyrophosphate phosphatase	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] 
B  Flippase
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A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    AZ30_07085 transglycosylase	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
B  DD-Transpeptidase (Class B PBP)
C    AZ30_05660 penicillin-binding protein 1	K12552 pbpA; penicillin-binding protein 1 [EC:3.4.-.-] 
C    AZ30_07910 penicillin-binding protein 3	K12553 pbp3; penicillin-binding protein 3 [EC:3.4.-.-] 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    AZ30_03365 D-alanyl-D-alanine carboxypeptidase	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
B  Glycosyltransferase
C    AZ30_08755 transglycosylase	K12551 sgtA; monofunctional glycosyltransferase [EC:2.4.99.28] 
C    AZ30_09685 glycosyltransferase	K04478 sgtB; monofunctional glycosyltransferase [EC:2.4.99.28] 
C    AZ30_05320 cell division protein FtsW	K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] 
C    AZ30_11020 cell division protein FtsW	K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28] 
B  Transpeptidase
B  Carboxypeptidase
B  Endopeptidase
C    AZ30_03195 mannosyl-glycoprotein endo-beta-N-acetylglucosamidase	K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] 
C    AZ30_01065 peptidase M23	K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] 
C    AZ30_01395 glycyl-glycine endopeptidase	K08259 lytM; lysostaphin [EC:3.4.24.75] 
B  Sortase
C    AZ30_13250 sortase A	K07284 srtA; sortase A [EC:3.4.22.70] 
C    AZ30_05425 sortase B	K08600 srtB; sortase B [EC:3.4.22.71] 
B  Lytic transglycosylase
B  Amidase
C    AZ30_08305 cell wall amidase	K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
B  Structural protein
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#Last updated: May 15, 2025